The Effects of Calcium Phosphate-Chitosan Block Bone Graft on the Periodontal Regeneration in One Wall Intrabony Defects in Beagle Dogs

2007 ◽  
pp. 393-396
Author(s):  
Sung Koo Kim ◽  
Jung Seok Lee ◽  
Gyung Joon Chae ◽  
Ui Won Jung ◽  
Yong Keun Lee ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Bone Graft ◽  
Periodontal Regeneration ◽  
Beagle Dogs ◽  
Intrabony Defects ◽  
Block Bone Graft

The Effects of Calcium Phosphate-Chitosan Block Bone Graft on the Periodontal Regeneration in One Wall Intrabony Defects in Beagle Dogs

2007 ◽  
Vol 342-343 ◽  
pp. 393-396
Author(s):  
Sung Koo Kim ◽  
Jung Seok Lee ◽  
Gyung Joon Chae ◽  
Ui Won Jung ◽  
Yong Keun Lee ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Periodontal Regeneration ◽  
Combination Group ◽  
Control Group ◽  
Experimental Surgery ◽  
Beagle Dogs ◽  
Intrabony Defects ◽  
Chitosan Membrane ◽  
Experimental Group ◽  
Block Bone Graft

This study evaluated periodontal repair and biomaterial reaction following implantation of a newly fabricated calcium phosphate chitosan block bone and chitosan membrane on the regeneration of 1- wall intrabony defects in the beagle dogs. The surgical control group received a flap operation only, while experimental group was treated with calcium phosphate chitosan block bone and/or chitosan membrane. All dogs were uneventful healing without any complication. The subjects were sacrificed 8 weeks after the experimental surgery, and a comparative histological and histometric examination was done. Chitosan membrane group significantly enhanced bone regeneration compared to control, CaP-chitosan block bone and combination group. Chitosan membrane remnants were observed in chitosan and combination group, while CaP-chitosan bone materials were resorbed completely. These results suggest that Chitosan membrnae significantly enhanced bone and cementum formation in advanced periodontal defects.

The effects of noncrystalline calcium phosphate glass on the healing of 1-wall intrabony defects in beagle dogs

2004 ◽  
Vol 34 (1) ◽  
pp. 113 ◽  
Author(s):  
Dong-Hoon Baik ◽  
Sung-Joon Hwang ◽  
Chang-Sung Kim ◽  
Yong-Keun Lee ◽  
Kyoo-Sung Cho ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Phosphate Glass ◽  
Beagle Dogs ◽  
Intrabony Defects

Bone Formation of Intrabony Defects in Beagle Dogs Using Calcium Phosphate Glass and Glass-Ceramics

2005 ◽  
pp. 957-960
Author(s):  
Seong Ho Choi ◽  
D.H. Baik ◽  
C.S. Kim ◽  
Chong Kwan Kim ◽  
Kyoung Nam Kim ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Bone Formation ◽  
Phosphate Glass ◽  
Glass Ceramics ◽  
Beagle Dogs ◽  
Intrabony Defects

Effect of Nano Biphasic Calcium Phosphate Bioceramics on Periodontal Regeneration in the Treatment of Alveolar Defects

2012 ◽  
Vol 486 ◽  
pp. 422-425 ◽  
Author(s):  
Lan Lei Wang ◽  
Ji Hua Li ◽  
Yong Tao Xie ◽  
Pi Shan Yang ◽  
Yun Mao Liao ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Biphasic Calcium Phosphate ◽  
Alveolar Bone ◽  
Periodontal Regeneration ◽  
Bone Defects ◽  
Beagle Dogs ◽  
Control Groups ◽  
Negative Controls ◽  
Osseous Defects ◽  
Positive Controls

The aim of the present study is to investigate the efficacy of nanobiphasic calcium phosphate (nanoBCP) bioceramic in the treatment of periodontal osseous defects. Alveolar bone defects were surgically created bilaterally at the buccal aspects of four second premolars in two beagle dogs. After root leveling, nanoBCP was randomly filled in one defect and nothing was put into the contralateral defect as negative controls. Bioglass was randomly filled in one of left defect as positive controls and nothing was put into the contralateral defect as negative controls. Dogs were killed at the 12th week. Histological observations were processed through a light microscopy. The results reveal that a great amount of functional periodontal fissures formed in the defects in the nanoBCP groups and bioglass groups while no new bone formed in the control groups at all. In this study, nanoBCP has proven to work well as a biocompatible and bioactive material to promote periodontal regeneration effectively.

The Effects of Chitosan-Tetracycline Membrane on Periodontal Regeneration of One-Wall Intrabony Defects in Beagle Dogs

2007 ◽  
Vol 342-343 ◽  
pp. 361-364
Author(s):  
Kwang Hee Han ◽  
Gyung Joon Chae ◽  
Jung Yoo Choi ◽  
Ui Won Jung ◽  
Yong Keun Lee ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Periodontal Regeneration ◽  
Junctional Epithelium ◽  
Experimental Surgery ◽  
Beagle Dogs ◽  
Intrabony Defects ◽  
Tissue Adhesion ◽  
Chitosan Membrane ◽  
Chitosan Membranes ◽  
Regeneration Of Bone

The aim of this study was to evaluate the regenerative effects of chitosan membranes containing tetracycline (TC) applied to surgically created one-wall intrabony defects in beagle dogs. The defects either received chitosan membrane (CH), chitosan membrane containing 0.5%, 1% TC (CH-TC0.5, CH-TC1.0) or flap operation only. The animals were sacrificed 8 weeks after the experimental surgery, and comparative histological and histometric examinations were done. The amount of junctional epithelium migration and connective tissue adhesion did not show any statistically significant differences among the groups. The amount of new cementum regeneration, and new bone regeneration were significantly greater in CH-TC1.0 group than the control (P<0.05). The results suggest that chitosan membrane combined with 1.0% TC may have beneficial effect on the regeneration of bone and cementum in intrabony periodontal defects.

The Effects of Chitosan-Tetracycline Membrane on Periodontal Regeneration of One-Wall Intrabony Defects in Beagle Dogs

2007 ◽  
pp. 361-364
Author(s):  
Kwang Hee Han ◽  
Gyung Joon Chae ◽  
Jung Yoo Choi ◽  
Ui Won Jung ◽  
Yong Keun Lee ◽  
...  
Keyword(s):  
Periodontal Regeneration ◽  
Beagle Dogs ◽  
Intrabony Defects

Bone Formation of Intrabony Defects in Beagle Dogs Using Calcium Phosphate Glass and Glass-Ceramics

2005 ◽  
Vol 284-286 ◽  
pp. 957-960 ◽  
Author(s):  
Seong Ho Choi ◽  
D.H. Baik ◽  
C.S. Kim ◽  
Chong Kwan Kim ◽  
Kyoung Nam Kim ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Phosphate Glass ◽  
Alveolar Bone ◽  
Root Resorption ◽  
Glass Ceramics ◽  
Beagle Dogs ◽  
Sprague Dawley ◽  
Intrabony Defects ◽  
Prepared Glass ◽  
Significant Difference

The purpose of this study was to compare the bone regenerative effect of calcium phosphate glass and glass-ceramics in the system of CaO-CaF2-P2O5-MgO-ZnO, which is already reported that promoted the bone-like tissue formation in vitro and formed new bone in Sprague-Dawley rats. We prepared calcium phosphate glass and glass-ceramics with Ca/P ratio of 0.6 using the system CaO-CaF2-P2O5-MgO-ZnO and subsequently milled to 400 µm. 4×4 mm 1-wall intrabony defects of six beagle dogs were surgically created and used in this study. 8 weeks after transplantation of the prepared calcium phosphate glass and glass-ceramics in the experimental group 1 and 2, respectively, the animals were sacrificed. No root resorption or ankylosis were observed in all groups. It can be examined that the prepared glass-ceramics were more effective in alveolar bone regeneration with statistical signigicant difference. In cementum regeneration, both the prepared glass and glass-ceramics showed significantly different effect. However, there were no statistical significant difference neither in glass nor glass-ceramics in the amounts of junctional epithelium migration and connective tissue adhesion. Further study is required to control the flowability as well as reduce the absorption rate in vivo.

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