The Effects of Calcium Phosphate-Chitosan Block Bone Graft on the Periodontal Regeneration in One Wall Intrabony Defects in Beagle Dogs

2007 ◽  
Vol 342-343 ◽  
pp. 393-396
Author(s):  
Sung Koo Kim ◽  
Jung Seok Lee ◽  
Gyung Joon Chae ◽  
Ui Won Jung ◽  
Yong Keun Lee ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Periodontal Regeneration ◽  
Combination Group ◽  
Control Group ◽  
Experimental Surgery ◽  
Beagle Dogs ◽  
Intrabony Defects ◽  
Chitosan Membrane ◽  
Experimental Group ◽  
Block Bone Graft

This study evaluated periodontal repair and biomaterial reaction following implantation of a newly fabricated calcium phosphate chitosan block bone and chitosan membrane on the regeneration of 1- wall intrabony defects in the beagle dogs. The surgical control group received a flap operation only, while experimental group was treated with calcium phosphate chitosan block bone and/or chitosan membrane. All dogs were uneventful healing without any complication. The subjects were sacrificed 8 weeks after the experimental surgery, and a comparative histological and histometric examination was done. Chitosan membrane group significantly enhanced bone regeneration compared to control, CaP-chitosan block bone and combination group. Chitosan membrane remnants were observed in chitosan and combination group, while CaP-chitosan bone materials were resorbed completely. These results suggest that Chitosan membrnae significantly enhanced bone and cementum formation in advanced periodontal defects.

The Effects of Chitosan-Tetracycline Membrane on Periodontal Regeneration of One-Wall Intrabony Defects in Beagle Dogs

2007 ◽  
Vol 342-343 ◽  
pp. 361-364
Author(s):  
Kwang Hee Han ◽  
Gyung Joon Chae ◽  
Jung Yoo Choi ◽  
Ui Won Jung ◽  
Yong Keun Lee ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Periodontal Regeneration ◽  
Junctional Epithelium ◽  
Experimental Surgery ◽  
Beagle Dogs ◽  
Intrabony Defects ◽  
Tissue Adhesion ◽  
Chitosan Membrane ◽  
Chitosan Membranes ◽  
Regeneration Of Bone

The aim of this study was to evaluate the regenerative effects of chitosan membranes containing tetracycline (TC) applied to surgically created one-wall intrabony defects in beagle dogs. The defects either received chitosan membrane (CH), chitosan membrane containing 0.5%, 1% TC (CH-TC0.5, CH-TC1.0) or flap operation only. The animals were sacrificed 8 weeks after the experimental surgery, and comparative histological and histometric examinations were done. The amount of junctional epithelium migration and connective tissue adhesion did not show any statistically significant differences among the groups. The amount of new cementum regeneration, and new bone regeneration were significantly greater in CH-TC1.0 group than the control (P<0.05). The results suggest that chitosan membrane combined with 1.0% TC may have beneficial effect on the regeneration of bone and cementum in intrabony periodontal defects.

Effect of Calcium Phosphate Glass Scaffold with Chitosan Membrane on the Healing of Alveolar Bone in 1 Wall Intrabony Defect in the Beagle Dogs

2005 ◽  
Vol 284-286 ◽  
pp. 851-854 ◽  
Author(s):  
D.H. Min ◽  
M.J. Kim ◽  
J.H. Yun ◽  
C.S. Kim ◽  
Yong Keun Lee ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Alveolar Bone ◽  
Root Resorption ◽  
Control Group ◽  
Beagle Dogs ◽  
Chitosan Membrane ◽  
Group I ◽  
Group Ii ◽  
Histological Results ◽  
Experimental Group

This study evaluated periodontal repair and biomaterial reaction following implantation of a newly fabricated calcium phosphate block bone with chitosan membrane on the regeneration of 1-wall intrabony defects in the beagle dogs. The surgical control group received a flap operation only, while the experimental group I was treated with a chitosan nonwoven membrane only and the experimental group II was treated with a chitosan nonwoven membrane and a calcium phosphate block bone. The subjects were sacrificed 12 weeks after surgery and a comparative histometric analysis was done. No root resorption or ankylosis were observed in the experimental group. Mann-Whitney U test showed that the experimental group II produced statistically significant higher gain in connective tissue adhesion, new cementum regeneration and new bone formation. Based on histological results, the calcium phosphate block bone successfully functioned as a osteoconductive scaffold for invading cells of host.

The Effect of Calcium Aluminate Bone Cement Incorporating LiF-Maleic Acid on the Bone Regeneration of 1-Wall Intrabony Defects in Beagle Dogs

2005 ◽  
Vol 284-286 ◽  
pp. 847-850
Author(s):  
H.W. Lee ◽  
S.U. Im ◽  
S.E. Song ◽  
C.S. Kim ◽  
Se Young Choi ◽  
...  
Keyword(s):  
Calcium Aluminate ◽  
Maleic Acid ◽  
Control Group ◽  
Graft Material ◽  
Beagle Dogs ◽  
Intrabony Defects ◽  
Defect Site ◽  
Periodontal Tissue Regeneration ◽  
Aluminate Cement ◽  
Experimental Group

This study evaluated periodontal repair and biomaterial reaction following implantation of a newly fabricated calcium aluminate bony cement incorporating LiF-maleic acid on the regeneration of 1-wall intrabony defects in the beagle dogs. The surgical control group received a flap operation only, while the experimental group was treated with calcium aluminate bony cement incorporating LiF-maleic acid. The subjects were sacrificed 12 weeks after surgery and a comparative histologic analysis was done. In the experimental group, the grafted calcium aluminate cement was not absorbed and fibrous connective tissue was epithelized around the particles of the grafted bony cement. Because of certain favorable properties, such as its easy manipulation and its ability to maintain the morphology of the defect site by acting as a scaffold, the newly developed cement is suitable for us as a graft material, and could be used very effectively in alveolar augmentation. However, further study needs to be conducted before it can be used as a bone graft material for periodontal tissue regeneration.

The effects of noncrystalline calcium phosphate glass on the healing of 1-wall intrabony defects in beagle dogs

2004 ◽  
Vol 34 (1) ◽  
pp. 113 ◽  
Author(s):  
Dong-Hoon Baik ◽  
Sung-Joon Hwang ◽  
Chang-Sung Kim ◽  
Yong-Keun Lee ◽  
Kyoo-Sung Cho ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Phosphate Glass ◽  
Beagle Dogs ◽  
Intrabony Defects

Bone Formation of Intrabony Defects in Beagle Dogs Using Calcium Phosphate Glass and Glass-Ceramics

2005 ◽  
pp. 957-960
Author(s):  
Seong Ho Choi ◽  
D.H. Baik ◽  
C.S. Kim ◽  
Chong Kwan Kim ◽  
Kyoung Nam Kim ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Bone Formation ◽  
Phosphate Glass ◽  
Glass Ceramics ◽  
Beagle Dogs ◽  
Intrabony Defects

Effects of Mixture of Fibrin-Fibronectin Sealant System and Calcium Carbonate in Periodontal Intrabony Defects

2006 ◽  
Vol 309-311 ◽  
pp. 1397-1400
Author(s):  
Ui Won Jung ◽  
S.J. Chang ◽  
Seong Ho Choi ◽  
C.S. Kim ◽  
Jung Kiu Chai
Keyword(s):  
Calcium Carbonate ◽  
Gingival Recession ◽  
Control Group ◽  
Intrabony Defects ◽  
Clinical Attachment Level ◽  
Intrabony Defect ◽  
Probing Depth ◽  
Group 2 ◽  
Attachment Level ◽  
Experimental Group

This study evaluated the effects of mixture of fibrin-fibronectin sealant system(FFSS) and calcium carbonate(CC) in periodontal intrabony defects. Thirty six sites with two or three wall intrabony defect were used. 14 defects treated with periodontal flap surgery were assigned as the control group. 11 defects treated with CC implantation were designed as experimental group 1 and 11 defects, treated with CC and FFSS implantation as experimental group 2. The control and experimental groups all achieved statistically significant improvements in probing depth and clinical attachment level from the baseline (P<0.01). In mean postsurgery probing depth and gingival recession reduction, there were no statiscally significant differences between the experimental groups and the controls. However, mean postsurgery clinical attachment levels of both experimental groups improved significantly more than that of the controls. As a result, we suggest that mixture of FFSS and CC can be used effectively in intrabony defect as osteoconductive materials.

Effect of Nano Biphasic Calcium Phosphate Bioceramics on Periodontal Regeneration in the Treatment of Alveolar Defects

2012 ◽  
Vol 486 ◽  
pp. 422-425 ◽  
Author(s):  
Lan Lei Wang ◽  
Ji Hua Li ◽  
Yong Tao Xie ◽  
Pi Shan Yang ◽  
Yun Mao Liao ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Biphasic Calcium Phosphate ◽  
Alveolar Bone ◽  
Periodontal Regeneration ◽  
Bone Defects ◽  
Beagle Dogs ◽  
Control Groups ◽  
Negative Controls ◽  
Osseous Defects ◽  
Positive Controls

The aim of the present study is to investigate the efficacy of nanobiphasic calcium phosphate (nanoBCP) bioceramic in the treatment of periodontal osseous defects. Alveolar bone defects were surgically created bilaterally at the buccal aspects of four second premolars in two beagle dogs. After root leveling, nanoBCP was randomly filled in one defect and nothing was put into the contralateral defect as negative controls. Bioglass was randomly filled in one of left defect as positive controls and nothing was put into the contralateral defect as negative controls. Dogs were killed at the 12th week. Histological observations were processed through a light microscopy. The results reveal that a great amount of functional periodontal fissures formed in the defects in the nanoBCP groups and bioglass groups while no new bone formed in the control groups at all. In this study, nanoBCP has proven to work well as a biocompatible and bioactive material to promote periodontal regeneration effectively.

scholarly journals Plasma Treatment Maintains Surface Energy of the Implant Surface and Enhances Osseointegration

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Fernando P. S. Guastaldi ◽  
Daniel Yoo ◽  
Charles Marin ◽  
Ryo Jimbo ◽  
Nick Tovar ◽  
...  
Keyword(s):  
Surface Energy ◽  
Photoelectron Spectroscopy ◽  
Nonthermal Plasma ◽  
Control Group ◽  
Beagle Dogs ◽  
Implant Surface ◽  
X Ray ◽  
Significant Difference ◽  
Bone To Implant Contact ◽  
Experimental Group

The surface energy of the implant surface has an impact on osseointegration. In this study, 2 surfaces: nonwashed resorbable blasting media (NWRBM; control) and Ar-based nonthermal plasma 30 days (Plasma 30 days; experimental), were investigated with a focus on the surface energy. The surface energy was characterized by the Owens-Wendt-Rabel-Kaelble method and the chemistry by X-ray photoelectron spectroscopy (XPS). Five adult beagle dogs received 8 implants (n=2per surface, per tibia). After 2 weeks, the animals were euthanized, and half of the implants (n=20) were removal torqued and the other half were histologically processed (n=20). The bone-to-implant contact (BIC) and bone area fraction occupancy (BAFO) were evaluated on the histologic sections. The XPS analysis showed peaks of C, Ca, O, and P for the control and experimental surfaces. While no significant difference was observed for BIC parameter (P>0.75), a higher level for torque (P<0.02) and BAFO parameter (P<0.01) was observed for the experimental group. The surface elemental chemistry was modified by the plasma and lasted for 30 days after treatment resulting in improved biomechanical fixation and bone formation at 2 weeks compared to the control group.

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