Nanofibers/PVA Blended Nano Fibre Matrix for Nervous Tissue Regeneration

2013 ◽  
Vol 404 ◽  
pp. 95-99 ◽  
Author(s):  
Ping Zhang ◽  
Shan Shan Wu
Keyword(s):  
Peripheral Nerve ◽  
Tissue Regeneration ◽  
Nervous Tissue ◽  
Electrospun Nanofibers ◽  
Neurite Growth ◽  
Stem Cell Differentiation ◽  
Poly Vinyl Alcohol ◽  
New Class ◽  
Nanofibrous Scaffolds ◽  
Fibre Matrix

Nanofibers produced by electrospinning represent a new class of promising scaffolds to support nerve regeneration. Here, we found that the blended solutions of chitosan (CS) with Poly (vinyl alcohol) (PVA) are appropriate for electrospinning when they form conductive, unstructured fluids displaying plasticity, rather than elasticity, in the bulk and at the interface. We then studied that utilize electrospun nanofibers to manipulate biological processes relevant to nervous tissue regeneration, including stem cell differentiation, guidance of neurite extension, and peripheral nerve injury treatments. The main objective of this article is to provide valuable methods for investigating the mechanisms of neurite growth on novel nanofibrous scaffolds and optimization of the nanofiber scaffolds and conduits for repairing peripheral nerve injuries.

Metalloproteinases as mediators of tissue regeneration in the peripheral nerve: an important role for metalloproteinase-2

2007 ◽  
Vol 34 (S 2) ◽  
Author(s):  
A Köhne ◽  
HC Lehmann ◽  
O Kiehl ◽  
G Meyer zu Hörste ◽  
HP Hartung ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Tissue Regeneration

Branched/Hyperbranched Copolyesters from Poly(vinyl alcohol) and Citric Acid as Delivery Agents and Tissue Regeneration Scaffolds

2021 ◽  
pp. 2100134
Author(s):  
Srijoni Sengupta ◽  
Abhishek Singh ◽  
Koushik Dutta ◽  
Ram Prasad Sahu ◽  
Satish Kumar ◽  
...  
Keyword(s):  
Citric Acid ◽  
Tissue Regeneration ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol

scholarly journals Electrospun Nanofibers of Natural and Synthetic Polymers as Artificial Extracellular Matrix for Tissue Engineering

Nanomaterials ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 21
Author(s):  
Mina Keshvardoostchokami ◽  
Sara Seidelin Majidi ◽  
Peipei Huo ◽  
Rajan Ramachandran ◽  
Menglin Chen ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Polymer Composite ◽  
Electrospun Nanofibers ◽  
Synthetic Polymer ◽  
Inorganic Materials ◽  
Host Cells ◽  
Natural Polymer ◽  
Reinforced Polymers ◽  
Nanofibrous Scaffolds ◽  
Artificial Extracellular Matrix

Many types of polymer nanofibers have been introduced as artificial extracellular matrices. Their controllable properties, such as wettability, surface charge, transparency, elasticity, porosity and surface to volume proportion, have attracted much attention. Moreover, functionalizing polymers with other bioactive components could enable the engineering of microenvironments to host cells for regenerative medical applications. In the current brief review, we focus on the most recently cited electrospun nanofibrous polymeric scaffolds and divide them into five main categories: natural polymer-natural polymer composite, natural polymer-synthetic polymer composite, synthetic polymer-synthetic polymer composite, crosslinked polymers and reinforced polymers with inorganic materials. Then, we focus on their physiochemical, biological and mechanical features and discussed the capability and efficiency of the nanofibrous scaffolds to function as the extracellular matrix to support cellular function.

Influence of Post-Treatment with Methanol Vapor on the Properties of SF/P(LLA-CL) Nanofibrous Scaffolds

2011 ◽  
Vol 236-238 ◽  
pp. 2221-2224
Author(s):  
Kui Hua Zhang ◽  
Xiu Mei Mo
Keyword(s):  
Electrospun Nanofibers ◽  
Random Coil ◽  
Methanol Vapor ◽  
Nanofibrous Scaffolds ◽  
Nanofibrous Structure ◽  
Α Helix ◽  
Β Sheet ◽  
Ideal Method ◽  
C Nmr

In order to improve water-resistant ability silk fibroin (SF) and SF/P(LLA-CL) blended nanofibrous scaffolds for tissue engineering applications, methanol vapor were used to treat electrospun nanofibers. SEM indicated SF and SF/ P(LLA-CL) scaffolds maintained nanofibrous structure after treated with methanol vapor and possessed good water-resistant ability. Characterization of 13C NMR clarified methanol vapor induced SF conformation from random coil or α- helix to β-sheet. Moreover, treated SF/ P (LLA-CL) nanofibrous scaffolds still kept good mechanical properties. Methanol vapor could be ideal method to treat SF and SF/ P(LLA-CL) nanofibrous scaffolds for biomedical applications.

ChemInform Abstract: Electrosprayed Nanoparticles and Electrospun Nanofibers Based on Natural Materials: Applications in Tissue Regeneration, Drug Delivery and Pharmaceuticals

ChemInform ◽  
2015 ◽  
Vol 46 (15) ◽  
pp. no-no
Author(s):  
Radhakrishnan Sridhar ◽  
Rajamani Lakshminarayanan ◽  
Kalaipriya Madhaiyan ◽  
Veluchamy Amutha Barathi ◽  
Keith Hsiu Chin Lim ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Tissue Regeneration ◽  
Electrospun Nanofibers ◽  
Natural Materials
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