Low-Flux Neutron Radiation Detection Technology with High Sensitivity

2014 ◽  
Vol 668-669 ◽  
pp. 924-927
Author(s):  
Yang Liu ◽  
Zhen Ni Xing ◽  
Guo Zheng Zhu

Boron-containing plastic scintillator detectors have a high detection efficiency for low-intensity thermal neutrons and fast neutrons which is currently the preferred types of neutron detector. This article is based on Monte Carlo method, studied boron-containing plastic scintillator for neutron detection performance, and analysis the energy deposition flux characteristics and detection efficiency when low intensity fission neutron incident to the boron plastic scintillator. We obtain the low-flux neutron detector performance in a variety of neutron source energy, boron-containing plastic scintillator diameter and length. Results showed that, when the boron-containing plastic scintillator lengths increase, the energy deposition flux will increase. When the length and diameter is constant, increasing source strength can increase the energy deposition flux brought by the recoil proton to a certain extent. When the source intensity over after thermal neutrons, due to the decrease of the cross section, the energy deposition fluxes brought by the react of neutrons and will decrease. The results provide help for low intensity fission neutron radiation detection technology with high sensitivity.

2014 ◽  
Vol 668-669 ◽  
pp. 1011-1014
Author(s):  
Yang Liu ◽  
Guo Zheng Zhu ◽  
Zhen Ni Xing

Gallium nitride (GaN) is the third generation of semiconductor material; it has a large band gap, high thermal conductivity, low dielectric constant, high drift speed, etc. Radiation detectors based on GaN material have small volume, high radiation resistance, and fast response, can be used to replace the existing Large Hadron Collider vertex detector and track detector. Energy deposition characteristic of GaN detectors to radiation beam is an important factor for detection efficiency, and there are many factors that affect the energy deposition characteristics of the detector, like the detection mechanism, the impact of material properties, the type of incident ray, radiation energy, and many other factors. This paper studies the physical properties of GaN detector by calculation based on Monte Carlo simulation. Energy deposition characteristics are discussed respectively for incident γ-ray with different energy, in the front-end and back-end add PTFE material. The results of our study present the theoretical properties of GaN radiation detectors.


Author(s):  
Elena I. Sarapultseva ◽  
Darya V. Uskalova ◽  
Ksenya V. Ustenko

Despite the fact that there are still conflicting opinions about the damage caused by modern wireless communication technologies, most scientists report on the negative biological effects of low-intensity radio frequency electromagnetic radiation at different levels of the organization of live nature. There is no doubt that there is a need not only for a sanitary and hygienic assessment of man-made electromagnetic effects on humans, but also for an environmental assessment for biota. The purpose of the study was to assess the potential environmental risk of electromagnetic impact in the centimeter range on natural ecosystems. The initial data were the authors' own results in the field of radiobiology of non-ionizing radiation, as well as published of other researchers. The article analyzes the biological effects of radio frequency electromagnetic fields detected in organisms of different systematic groups and levels of organization. The data on the non-thermal biological effects of electromagnetic fields indicate a high sensitivity of different species to this factor. The analyzed research results emphasize the need to take into account the features of non-thermal effects of electromagnetic radiation on biota, since these radiations can have a negative impact on different hierarchical levels in natural ecosystems.


Nanomaterials ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1942
Author(s):  
Xiaoqing Zeng ◽  
Yang Xiang ◽  
Qianshan Liu ◽  
Liang Wang ◽  
Qianyun Ma ◽  
...  

Protein is an important component of all the cells and tissues of the human body and is the material basis of life. Its content, sequence, and spatial structure have a great impact on proteomics and human biology. It can reflect the important information of normal or pathophysiological processes and promote the development of new diagnoses and treatment methods. However, the current techniques of proteomics for protein analysis are limited by chemical modifications, large sample sizes, or cumbersome operations. Solving this problem requires overcoming huge challenges. Nanopore single molecule detection technology overcomes this shortcoming. As a new sensing technology, it has the advantages of no labeling, high sensitivity, fast detection speed, real-time monitoring, and simple operation. It is widely used in gene sequencing, detection of peptides and proteins, markers and microorganisms, and other biomolecules and metal ions. Therefore, based on the advantages of novel nanopore single-molecule detection technology, its application to protein sequence detection and structure recognition has also been proposed and developed. In this paper, the application of nanopore single-molecule detection technology in protein detection in recent years is reviewed, and its development prospect is investigated.


1968 ◽  
Vol 58 (1) ◽  
pp. 57-60 ◽  
Author(s):  
F.P. Brady ◽  
J.A. Jungerman ◽  
J.C. Young ◽  
J.L. Romero ◽  
P.J. Symonds

Author(s):  
Zhijia Peng ◽  
Xiaogang Lin ◽  
Weiqi Nian ◽  
Xiaodong Zheng ◽  
Jayne Wu

Early diagnosis and treatment have always been highly desired in the fight against cancer, and detection of circulating tumor DNA (ctDNA) has recently been touted as highly promising for early cancer screening. Consequently, the detection of ctDNA in liquid biopsy gains much attention in the field of tumor diagnosis and treatment, which has also attracted research interest from the industry. However, traditional gene detection technology is difficult to achieve low cost, real-time and portable measurement of ctDNA. Electroanalytical biosensors have many unique advantages such as high sensitivity, high specificity, low cost and good portability. Therefore, this review aims to discuss the latest development of biosensors for minimal-invasive, rapid, and real-time ctDNA detection. Various ctDNA sensors are reviewed with respect to their choices of receptor probes, detection strategies and figures of merit. Aiming at the portable, real-time and non-destructive characteristics of biosensors, we analyze their development in the Internet of Things, point-of-care testing, big data and big health.


2019 ◽  
Vol 24 ◽  
pp. 92
Author(s):  
J. Kalef-Ezra ◽  
S. Valakis

Radon-222 is classified in the Group I of the human carcinogens. The in situ decay of inhaled 222Rn and its short-lived decay products (T1/2 <30 min) is the main source of radiation burden to the general population of natural origin. The corresponding effective dose is routinely calculated as the product of the 222Rn concentration in air, a predetermined dosimetric constant and a factor that depends on the space type (e.g. residential or public building, cave, mine, etc). However, in practice, there are large spatial and temporal variations in the activity ratio of each progeny to 222Rn in air, the characteristics of the progeny carrying particles and the metabolism of each progeny depending on air quality, as well as differences in the anatomic and physiological characteristics between individuals, that vary substantially even with time. Therefore, the currently employed dosimetric approach may introduce large uncertainties. In the hypothetical case of acute deposition and full retention in the human body of equal activities of all 222Rn progeny, about 93% of the effective dose is due to the decaying 214Po. The 214Po activity can be assessed by measurement of its γ-emitting precursor, 214Bi, which is in full equilibrium with 214Po in the human body. The 214Bi activity can be measured using a high-sensitivity whole-body counter with high counting uniformity, such as the one in use at the Ioannina University Medical Physics Department. Its detection efficiency and its dependence on body shape and size were assessed by Monte Carlo simulations. Measurements carried out in healthy adult volunteers residing at a short distance from the counter, indicated a mean total body 214Bi activity (TBBi) of ~100 Bq during the cold season of the year and lower during the hot one. Higher mean TBBi levels were found in male than in female adults. Therefore, TBBi measurements may allow for accurate radon-related risk assessment on individual base.


2015 ◽  
Vol 308 (8) ◽  
pp. H875-H883 ◽  
Author(s):  
Glenn M. Stewart ◽  
Akira Yamada ◽  
Luke J. Haseler ◽  
Justin J. Kavanagh ◽  
Gus Koerbin ◽  
...  

Transient reductions in myocardial strain coupled with cardiac-specific biomarker release have been reported after prolonged exercise (>180 min). However, it is unknown if 1) shorter-duration exercise (60 min) can perturb cardiac function or 2) if exercise-induced reductions in strain are masked by hemodynamic changes that are associated with passive recovery from exercise. Left ventricular (LV) and right ventricular global longitudinal strain (GLS), LV torsion, and high-sensitivity cardiac troponin T were measured in 15 competitive cyclists (age: 28 ± 3 yr, peak O2 uptake: 4.8 ± 0.6 l/min) before and after a 60-min high-intensity cycling race intervention (CRIT60). At both time points (pre- and post-CRIT60), strain and torsion were assessed at rest and during a standardized low-intensity exercise challenge (power output: 96 ± 8 W) in a semirecumbent position using echocardiography. During rest, hemodynamic conditions were different from pre- to post-CRIT60 (mean arterial pressure: 96 ± 1 vs. 86 ± 2 mmHg, P < 0.001), and there were no changes in strain or torsion. In contrast, during the standardized low-intensity exercise challenge, hemodynamic conditions were unchanged from pre- to post-CRIT60 (mean arterial pressure: 98 ± 1 vs. 97 ± 1 mmHg, not significant), but strain decreased (left ventricular GLS: −20.3 ± 0.5% vs. −18.5 ± 0.4%, P < 0.01; right ventricular GLS: −26.4 ± 1.6% vs. −22.4 ± 1.5%, P < 0.05), whereas LV torsion remained unchanged. Serum high-sensitivity cardiac troponin T increased by 345% after the CRIT60 (6.0 ± 0.6 vs. 20.7 ± 6.9 ng/l, P < 0.05). This study demonstrates that exercise-induced functional and biochemical cardiac perturbations are not confined to ultraendurance sporting events and transpire during exercise that is typical of day-to-day training undertaken by endurance athletes. The clinical significance of cumulative exposure to endurance exercise warrants further study.


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