Application of Cold Atmospheric Pressure Plasmas for Biological Tissue Treatment

2015 ◽  
Vol 1084 ◽  
pp. 602-605 ◽  
Author(s):  
Aleksandr N. Aleinik ◽  
Aleksandr N. Baykov ◽  
Georgiy Ts. Dambaev ◽  
Evgeniy V. Semichev
Keyword(s):  
Biological Tissue ◽  
Atmospheric Pressure ◽  
Atmospheric Pressure Plasma ◽  
Air Plasma ◽  
Plasma Technology ◽  
Large Application ◽  
Wet Chemical ◽  
Discharge Gap ◽  
Air Plasma Treatment

New experiments using atmospheric pressure plasma have found large application in biology and medicine. Cold air plasma treatment can be used to modify the surface of different materials for a variety of applications. The emission spectroscopy data confirmed the presence of different reactive species in the discharge gap. Surface treatments using this dry plasma technology offer an environmentally friendly alternative to the conventional wet chemical methods of microorganisms destruction, biological tissue treatment, in vitro and in vivo cell treatment. The use of cold plasma technology removes contaminants at the nanometer level.

Cold atmospheric-pressure air plasma treatment of C6 glioma cells: effects of reactive oxygen species in the medium produced by the plasma on cell death

2017 ◽  
Vol 19 (2) ◽  
pp. 025503 ◽  
Author(s):  
Yuyang Wang (汪宇扬) ◽  
Cheng Cheng (程诚) ◽  
Peng Gao (高鹏) ◽  
Shaopeng Li (李少鹏) ◽  
Jie Shen (沈洁) ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Cell Death ◽  
Plasma Treatment ◽  
Atmospheric Pressure ◽  
Glioma Cells ◽  
C6 Glioma ◽  
C6 Glioma Cells ◽  
Oxygen Species ◽  
Air Plasma ◽  
Air Plasma Treatment

Atmospheric pressure air plasma treatment to improve the 3D printing of polyoxymethylene

2019 ◽  
Vol 16 (7) ◽  
Author(s):  
Ignacio Muro‐Fraguas ◽  
Elisa Sainz‐García ◽  
Alpha Pernía‐Espinoza ◽  
Fernando Alba‐Elías
Keyword(s):  
3D Printing ◽  
Plasma Treatment ◽  
Atmospheric Pressure ◽  
Air Plasma ◽  
Air Plasma Treatment

scholarly journals Effects of Cold Jet Atmospheric Pressure Plasma on the Structural Characteristics and Immunoreactivity of Celiac-Toxic Peptides and Wheat Storage Proteins

2020 ◽  
Vol 21 (3) ◽  
pp. 1012
Author(s):  
Fusheng Sun ◽  
Xiaoxue Xie ◽  
Yufan Zhang ◽  
Jiangwei Duan ◽  
Mingyu Ma ◽  
...  
Keyword(s):  
Atmospheric Pressure ◽  
Storage Proteins ◽  
Structural Characteristics ◽  
Atmospheric Pressure Plasma ◽  
High Energy ◽  
Backbone Cleavage ◽  
Excited Atoms ◽  
Wheat Storage Proteins ◽  
Toxic Peptides

The present research reported the effects of structural properties and immunoreactivity of celiac-toxic peptides and wheat storage proteins modified by cold jet atmospheric pressure (CJAP) plasma. It could generate numerous high-energy excited atoms, photons, electrons, and reactive oxygen and nitrogen species, including O3, H2O2, •OH, NO2− and NO3− etc., to modify two model peptides and wheat storage proteins. The Orbitrap HR-LC-MS/MS was utilized to identify and quantify CJAP plasma-modified model peptide products. Backbone cleavage of QQPFP and PQPQLPY at specific proline and glutamine residues, accompanied by hydroxylation at the aromatic ring of phenylalanine and tyrosine residues, contributed to the reduction and modification of celiac-toxic peptides. Apart from fragmentation, oxidation, and agglomeration states were evaluated, including carbonyl formation and the decline of γ-gliadin. The immunoreactivity of gliadin extract declined over time, demonstrating a significant decrease by 51.95% after 60 min of CJAP plasma treatment in vitro. The CJAP plasma could initiate depolymerization of gluten polymer, thereby reducing the amounts of large-sized polymers. In conclusion, CJAP plasma could be employed as a potential technique in the modification and reduction of celiac-toxic peptides and wheat storage proteins.

scholarly journals Infrared Absorption Spectroscopic Study on Reaction between Self-Assembled Monolayers and Atmospheric-Pressure Plasma

2015 ◽  
Vol 2015 ◽  
pp. 1-7
Author(s):  
Masanori Shinohara ◽  
Katsuhiro Amano ◽  
Naoki Maruno ◽  
Yuta Yoshida ◽  
Yoshinobu Matsuda ◽  
...  
Keyword(s):  
Protein Interactions ◽  
Atmospheric Pressure ◽  
Water Clusters ◽  
Atmospheric Pressure Plasma ◽  
Air Plasma ◽  
Self Assembled Monolayer ◽  
Pressure Plasma ◽  
Assembled Monolayers ◽  
Self Assembled ◽  
Living Tissues

Plasma is becoming increasingly adopted in bioapplications such as plasma medicine and agriculture. This study investigates the interaction between plasma and molecules in living tissues, focusing on plasma-protein interactions. To this end, the reaction of air-pressure air plasma with NH2-terminated self-assembled monolayer is investigated by infrared spectroscopy in multiple internal reflection geometry. The atmospheric-pressure plasma decomposed the NH2components, the characteristic units of proteins. The decomposition is attributed to water clusters generated in the plasma, indicating that protein decomposition by plasma requires humid air.

scholarly journals The Effects of Atmospheric Pressure Argon Plasma Treated Bovine Bone Substitute on Bone Regeneration

Coatings ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. 790
Author(s):  
Jong-Ju Ahn ◽  
Ji-Hyun Yoo ◽  
Eun-Bin Bae ◽  
Gyoo-Cheon Kim ◽  
Jae Joon Hwang ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Atmospheric Pressure ◽  
Bone Substitute ◽  
Argon Plasma ◽  
Atmospheric Pressure Plasma ◽  
Regeneration Ability ◽  
Bovine Bone ◽  
Significant Difference

This study was undertaken to compare new bone formation between non-expired and expired bovine-derived xenogeneic bone substitute (expired, out-of-use period) and to evaluate the efficacy of argon (Ar)-based atmospheric pressure plasma (APP) treatment on expired bone substitute in rat calvarial defect. The groups were divided into (1) Non/Expired group (Using regular xenografts), (2) Expired group (Using expired xenografts), and (3) Ar/Expired group (Using Ar-based APP treated expired xenografts). Surface observation and cell experiments were performed in vitro. Twelve rats were used for in vivo experiment and the bony defects were created on the middle of the cranium. The bone substitute of each group was implanted into the defective site. After 4 weeks, all the rats were sacrificed, and the volumetric, histologic, and histometric analyses were performed. In the results of osteogenic differentiation and mineralization, Non/Expired and Ar/Expired groups were significantly higher than Expired group (p < 0.05). However, there was no significant difference between groups in the animal study (p > 0.05). Within the limitations of this study, the surface treatment of Ar-based APP has a potential effect on the surface modification of bone grafts. However, there was no significant difference in bone regeneration ability between groups in vivo; thus, studies on APP to enhance bone regeneration should be carried out in the future.

In Vitro Killing of Clinical Fungal Strains by Low-Temperature Atmospheric-Pressure Plasma Jet

2011 ◽  
Vol 39 (2) ◽  
pp. 815-821 ◽  
Author(s):  
Georg Daeschlein ◽  
Sebastian Scholz ◽  
Thomas von Woedtke ◽  
Maria Niggemeier ◽  
Eckhard Kindel ◽  
...  
Keyword(s):  
Low Temperature ◽  
Atmospheric Pressure ◽  
Atmospheric Pressure Plasma ◽  
Plasma Jet ◽  
Atmospheric Pressure Plasma Jet ◽  
Fungal Strains ◽  
Pressure Plasma

Influence of air plasma treatment at atmospheric pressure on wood extractives

2012 ◽  
Vol 97 (3) ◽  
pp. 469-471 ◽  
Author(s):  
G. Avramidis ◽  
L. Klarhöfer ◽  
W. Maus-Friedrichs ◽  
H. Militz ◽  
W. Viöl
Keyword(s):  
Plasma Treatment ◽  
Atmospheric Pressure ◽  
Air Plasma ◽  
Wood Extractives ◽  
Air Plasma Treatment
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