Antimicrobial Materials Derived from the Endophytic Fungus Fusarium sp. of Eucommia ulmoides

2012 ◽  
Vol 531 ◽  
pp. 346-349 ◽  
Author(s):  
Hong Chi Zhang ◽  
Yang Min Ma ◽  
Rui Liu
Keyword(s):  
Endophytic Fungus ◽  
Spectroscopic Analysis ◽  
Screening Program ◽  
Eucommia Ulmoides ◽  
Antibacterial And Antifungal Activities ◽  
Antimicrobial Materials ◽  
Fusarium Sp ◽  
Reported Data ◽  
Antibacterial And Antifungal ◽  
First Time

Within our screening program for antimicrobial materials, eight compounds (1-8) were isolated from an endophytic fungus Fusarium sp. of Eucommia ulmoides. Compound 1, 2, 5-8 were isolated for the first time from endophytic fungi. Their structures were elucidated on the basis of NMR spectroscopic analysis with the reported data in the literature. All compounds showed potent antibacterial and antifungal activities and can be use as new antimicrobial materials.

Antimicrobial Additives from Endophytic Fungus Fusarium solani of Ficus carica

2012 ◽  
Vol 178-181 ◽  
pp. 783-786 ◽  
Author(s):  
Hong Chi Zhang ◽  
Yang Min Ma ◽  
Rui Liu
Keyword(s):  
Fusarium Solani ◽  
Endophytic Fungus ◽  
Spectroscopic Analysis ◽  
Screening Program ◽  
Ficus Carica ◽  
Antifungal Activities ◽  
Antibacterial And Antifungal Activities ◽  
Antibacterial And Antifungal

Within our screening program for antimicrobial additives, six compounds were isolated from an endophytic fungus Fusarium solani of Ficus carica. Their structures were elucidated on the basis of spectroscopic analysis. Moreover, all of them showed potent antibacterial and antifungal activities.

(–)-Agelasidine A from Agelas clathrodes

2006 ◽  
Vol 61 (7-8) ◽  
pp. 472-476 ◽  
Author(s):  
Maria Augusta Medeiros ◽  
Ana Lourenço ◽  
Maria Regina Tavares ◽  
Maria João Marcelo Curto ◽  
Sónia Savluchinske Feio ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Marine Sponge ◽  
Methanol Extract ◽  
Spectroscopic Methods ◽  
Antifungal Activities ◽  
Antibacterial And Antifungal Activities ◽  
Bacteriostatic Agent ◽  
Antibacterial And Antifungal ◽  
First Time

(-)-Agelasidine A was identified from the methanol extract of the marine sponge Agelas clathrodes for the first time together with zooanemonin, 1-carboxymethylnicotinic acid, hymenidin, mukanadins A and C, monobromodispacamide, agelasidine D, 2-amide-4-bromopyrrole, O-methyltryptophan and an agelasines mixture. The structures were characterized by spectroscopic methods. (-)-Agelasidine A was tested for antibacterial and antifungal activities and shown to act as a bacteriostatic agent as it inhibited the growth of Staphylococcus aureus and partially the growth of other bacteria.

scholarly journals Structures of New Phenolic Glycosides from the Seeds of Cucurbita Moschata

2009 ◽  
Vol 4 (4) ◽  
pp. 1934578X0900400
Author(s):  
Li Fa-Sheng ◽  
Xu Jing ◽  
Dou De-Qiang ◽  
Chi Xiao-Feng ◽  
Kang Ting-Guo ◽  
...  
Keyword(s):  
Spectral Data ◽  
Spectroscopic Analysis ◽  
Phenolic Glycosides ◽  
Phenolic Glycoside ◽  
Cucurbita Moschata ◽  
Reported Data ◽  
First Time ◽  
Chemical Evidence

A new phenolic glycoside and three known compounds were isolated from the seeds of Cucurbita moschata. The structures of the new compound was elucidated as phenylcarbinyl 5-O-(4-hydroxy)benzoyl-β-D-apiofuranosyl (1→2)-β-D-glucopyranoside on the basis of spectroscopic analysis and chemical evidence. Three known compounds were identified as 1-O-benzyl[5-O-benzoyl-β-D-apiofuranosyl(1→2)]-β-D-glucopyranoside 2, cucurbitosides C 3 and A 4, by comparison of the spectral data with reported data. Compound 2 was isolated from this plant for the first time.

Aspernolides L and M, new butyrolactones from the endophytic fungus Aspergillus versicolor

2017 ◽  
Vol 72 (5-6) ◽  
pp. 155-160 ◽  
Author(s):  
Sabrin R.M. Ibrahim ◽  
Gamal A. Mohamed ◽  
Samir A. Ross
Keyword(s):  
Endophytic Fungi ◽  
Endophytic Fungus ◽  
Spectroscopic Analysis ◽  
2D Nmr ◽  
Systematic Search ◽  
Aspergillus Versicolor ◽  
Active Compounds ◽  
Etoac Extract ◽  
First Time

Abstract During the systematic search of active compounds from endophytic fungi, two new butyrolactones, namely aspernolides L (2) and M (4), together with four known compounds: 1-O-acetylglycerol (1), butyrolactone I (3), butyrolactone VI (5), and (+) alantrypinone (6) were characterized from the EtOAc extract of the endophytic fungus Aspergillus versicolor isolated from the roots of Pulicaria crispa (Asteraceae). Extensive spectroscopic analysis, including 1D, 2D NMR, and HRESIMS, was used to elucidate their structures. Compounds 1, 5, and 6 are reported for the first time from this fungus.

Secondary anti-fungi metabolites from the endophytic fungus Fusarium sp. in Eucommia ulmoides

2012 ◽  
Vol 48 (1) ◽  
pp. 170-171
Author(s):  
Yang-Min Ma ◽  
Hong-Chi Zhang ◽  
Jie Zhao ◽  
Xian-Qi Li
Keyword(s):  
Endophytic Fungus ◽  
Eucommia Ulmoides ◽  
Fusarium Sp

scholarly journals Screening for Genes Coding for Putative Antitumor Compounds, Antimicrobial and Enzymatic Activities from Haloalkalitolerant and Haloalkaliphilic Bacteria Strains of Algerian Sahara Soils

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Okba Selama ◽  
Gregory C. A. Amos ◽  
Zahia Djenane ◽  
Chiara Borsetto ◽  
Rabah Forar Laidi ◽  
...  
Keyword(s):  
Extreme Environments ◽  
Extreme Environment ◽  
Antibacterial And Antifungal Activities ◽  
Algerian Sahara ◽  
Antitumor Compounds ◽  
Haloalkaliphilic Bacteria ◽  
Novel Bacteria ◽  
Antibacterial And Antifungal ◽  
First Time ◽  
Bacterial Groups

Extreme environments may often contain unusual bacterial groups whose physiology is distinct from those of normal environments. To satisfy the need for new bioactive pharmaceuticals compounds and enzymes, we report here the isolation of novel bacteria from an extreme environment. Thirteen selected haloalkalitolerant and haloalkaliphilic bacteria were isolated from Algerian Sahara Desert soils. These isolates were screened for the presence of genes coding for putative antitumor compounds using PCR based methods. Enzymatic, antibacterial, and antifungal activities were determined by using cultural dependant methods. Several of these isolates are typical of desert and alkaline saline soils, but, in addition, we report for the first time the presence of a potential new member of the genusNocardiawith particular activity against the yeastSaccharomyces cerevisiae. In addition to their haloalkali character, the presence of genes coding for putative antitumor compounds, combined with the antimicrobial activity against a broad range of indicator strains and their enzymatic potential, makes them suitable for biotechnology applications.

scholarly journals Ring B Aromatic Steroids from an Endophytic Fungus, Colletotrichum sp.

2009 ◽  
Vol 4 (11) ◽  
pp. 1934578X0900401 ◽  
Author(s):  
Wen Zhang ◽  
Siegfried Draeger ◽  
Barbara Schulz ◽  
Karsten Krohn
Keyword(s):  
Escherichia Coli ◽  
Antimicrobial Activity ◽  
Bacillus Megaterium ◽  
Endophytic Fungus ◽  
Spectroscopic Analysis ◽  
Chemical Diversity ◽  
Chlorella Fusca ◽  
Microbotryum Violaceum ◽  
Reported Data ◽  
Insight Into

The new (22E,24R)-3-acetoxy-19(10→6)-abeo-ergosta-5,7,9,22-tetraen-3β-ol (1) and the known (22E,24R)-19(10→6)-abeo-ergosta-5,7,9,22-tetraen-3β-ol (2), two interesting ergosteroids with rare aromatized ring B, together with seven known derivatives, namely (22E,24R)-ergosta-5,7,22-trien-3β-ol (3), (22E,24R)-ergosta-4,7,22-trien-3-one (4), (22E,24R)-ergosta-4,6,8(14),22-tetraen-3-one (5), (22E,24R)-5α,8α-epidioxyergosta-6,22-dien-3β-ol (6), (22E,24R)-ergosta-7,22-dien-3β,5α,6β-triol (7), (22E,24R)-6-acetoxy-ergosta-7,22-dien-3β,5α,6β-triol (8), and (22E,24R)-3,6-diacetoxy-ergosta-7,22-dien-3β,5α,6β-triol (9), were isolated from Colletotrichum sp., an endophytic fungus isolated from Ilex canariensis from Gomera. The structures of these compounds were elucidated by detailed spectroscopic analysis, comparison with reported data, and chemical interconversion. The isolation of these metabolites not only displays a beautiful array of chemical diversity, but also gives insight into the biosynthetic interconnections. Preliminary studies showed antimicrobial activity of these compounds against the fungus Microbotryum violaceum, the alga Chlorella fusca, and the bacteria Escherichia coli and Bacillus megaterium.

An Invitro Study: Antioxidant, Phytochemical Analysis and Antimicrobial Activities of Achranthes aspera

2021 ◽  
pp. 268-277
Author(s):  
Masiraben Vahora ◽  
Falaknaaz Shaikh
Keyword(s):  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Antibacterial Activities ◽  
Antimicrobial Activities ◽  
Positive Control ◽  
Diffusion Method ◽  
Phytochemical Analysis ◽  
Antibacterial And Antifungal Activities ◽  
Fusarium Sp ◽  
Antibacterial And Antifungal

Medicaments, plants and plant-based are the basis of many of the modern pharmaceuticals we use today for our various purposes. The aim of the present study was to evaluate the antioxidant, phytochemical and antibacterial and antifungal activities of the Achyranthes aspera plant extract in different organic solvents. The radical scavenging activity of the different extracts of root, stem, leaf, and seed were evaluated by DPPH assay and the antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa, and antifungal activity against Fusarium sp. and Aspergillus niger was studied by Agar well cut diffusion method. All of the extracts exhibited different antioxidant and antibacterial activities and the activities varied from solvent to solvent, and the activities are concentrated. The antioxidant and antimicrobial activities were compared with the positive control Ascorbic acid and Cefuroxime. A qualitative phytochemical analysis was carried out and found to possess bioactive compounds like alkaloids, glycosides, terpenoids, steroids, flavonoids, tannins.

scholarly journals Puccinellia maritima, Spartina maritime, and Spartina patens Halophytic Grasses: Characterization of Polyphenolic and Chlorophyll Profiles and Evaluation of Their Biological Activities

Molecules ◽  
2019 ◽  
Vol 24 (20) ◽  
pp. 3796 ◽  
Author(s):  
Maria V. Faustino ◽  
Maria A. F. Faustino ◽  
Helena Silva ◽  
Ângela Cunha ◽  
Artur M. S. Silva ◽  
...  
Keyword(s):  
Biological Activities ◽  
Photophysical Properties ◽  
Spartina Patens ◽  
Point Of View ◽  
Antibacterial And Antifungal Activities ◽  
Antibacterial And Antifungal ◽  
Ferulic Acids ◽  
First Time ◽  
Halophytic Grasses

Halophytic grasses have been recently targeted as possible sources of nutraceutical and medicinal compounds. Nonetheless, few studies have been conducted on the phytochemistry and biological activities of metabolites produced by these plants. Among these, Spartina maritima (Curtis) Fernald, Spartina patens (Aiton.) Muhl., and Puccinellia maritima (Hudson) Parl. are three halophytic grasses whose chemical composition and bioactivities are unknown. The present work broadens the knowledge on the polyphenolic and chlorophyll composition of these species identifying for the first time hydroxycinnamic acids and their derivatives, flavones, flavonols, lignans, as well as chlorophylls and xantophylls. The extracts were particularly rich in caffeic and ferulic acids as well as in trihydroxymethoxyflavone, apigenin and tricin derivatives. Interestingly, several of the identified compounds are relevant from a medicinal and nutraceutical point of view putting in evidence the potential of these species. Thus, the antioxidant, anti-acetylcholinesterase, antibacterial, and antifungal activities of the polyphenolic extracts were assessed as well as the photophysical properties of the chlorophyll-rich extracts. The results, herein presented for the first time, reinforce the nutritional and the medicinal potential of these halophytic grasses.

scholarly journals Two Compounds from the Endophytic Colletotrichum sp. of Ginkgo biloba

2011 ◽  
Vol 6 (8) ◽  
pp. 1934578X1100600
Author(s):  
Sheng-Liang Zhou ◽  
Song-Lin Zhou ◽  
Mei-Xia Wang ◽  
Shuang-Lin Chen
Keyword(s):  
Spectral Data ◽  
Ginkgo Biloba ◽  
Endophytic Fungus ◽  
Spectroscopic Analysis ◽  
2D Nmr ◽  
Fermentation Products ◽  
First Time

Two compounds, apigenin-8- C-β-D-glucopyranoside and 2-(hydroxymethylthio)ethanol, were extracted from the fermentation products of a strain of endophytic fungus, Colletotrichum sp. NTB-2, isolated from the leafstalk of Ginkgo biloba. The structures of the two compounds were determined on the basis of extensive spectroscopic analysis, including 1D and 2D NMR spectral data. The compounds were obtained from microorganisms for the first time.

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