Preparation and Properties of Nanocomposites Containing FGF-2, other Related Dressings and the Primary Animal Tests

2012 ◽  
Vol 535-537 ◽  
pp. 406-410
Author(s):  
Te Hsing Wu ◽  
Hong Ru Lin ◽  
Lie Han Shen
Keyword(s):  
Testing Machine ◽  
Animal Experiments ◽  
Physical And Mechanical Properties ◽  
Healing Environment ◽  
Isopropyl Acrylamide ◽  
Hydrogel Composites ◽  
Enzyme Link Immunosorbent Assay ◽  
Material Testing Machine ◽  
Hydrogel Nanocomposite ◽  
Animal Tests

PU/ hydrogel composites or it containing fibroblast growth factor-2 (FGF-2) composites had been prepared by γ-ray radiation or room temperature(T) method in this paper. We utilized nanosized clay solution, thermosensitive N-isopropyl acrylamide (NIPAAm), Polyurethane (PU), and acrylic acid (AAc) as the starting materials to synthesize PU/hydrogel nanocomposite products. The dipping and weighing tests, Material Testing Machine (LLOYD) were employed to analyze the physical and mechanical properties differentially. In addition, the drug release and the wound closure in animal experiments were also finished by Enzyme-link immunosorbent assay( ELISA) reader and magnifier for five groups of treatment dressings. From the experimental results, we distinctly obtained that animal tests of the PU/hydrogel composite incorporating FGF-2 as a wound dressing was able to effectively interact with the wound in a suitable moist healing environment. From the results, we also gained that these composites make themselves more compatible with skin.

Wound Healing Based on PU/Hydrogel Nanocompounds Containing FGF-2 and Related Dressings by Radiation Method

2009 ◽  
Vol 79-82 ◽  
pp. 437-440 ◽  
Author(s):  
Te Hsing Wu ◽  
Hong Ru Lin ◽  
Lie Hang Shen ◽  
Jia Hau Liu
Keyword(s):  
Wound Closure ◽  
Testing Machine ◽  
Physical And Mechanical Properties ◽  
Healing Environment ◽  
Hydrogel Composite ◽  
Isopropyl Acrylamide ◽  
Radiation Technique ◽  
Enzyme Link Immunosorbent Assay ◽  
Material Testing Machine ◽  
Hydrogel Nanocomposite

PU/hydrogel compounds prepared byγ-ray radiation technique were investigated in this study. We used nanosized clay solution or powder, Polyurethane (PU), thermosensitive N-isopropyl acrylamide (NIPAAm) and acrylic acid (AAc) as starting materials to prepare PU/hydrogel nanocomposite products. The dipping and weighing tests, Material Testing Machine (LLOYD) were utilized to analyze the physical and mechanical properties differentially. In addition, the drug release and wound closure experiments were also finished by Enzyme-link immunosorbent assay (ELISA) reader and five groups of treatment dressings. From the final results, We obtained that the PU/hydrogel composite incorporating FGF-2 as a wound dressing was able to effectively interact with the wound in a suitable moist healing environment. These composites make them more compatible with skin.

scholarly journals Pressure Sensor System for Customized Scoliosis Braces

Sensors ◽  
2021 ◽  
Vol 21 (4) ◽  
pp. 1153
Author(s):  
Franz Konstantin Fuss ◽  
Asliza Ahmad ◽  
Adin Ming Tan ◽  
Rizal Razman ◽  
Yehuda Weizman
Keyword(s):  
Pressure Sensor ◽  
Testing Machine ◽  
Force Plate ◽  
Cost Effective ◽  
Mobile Systems ◽  
Sensor System ◽  
Closed Cell ◽  
Hard Shell ◽  
Energy Absorbers ◽  
Material Testing Machine

Hard-shell thoracolumbar sacral orthoses (TLSOs) are used for treating idiopathic scoliosis, a deformation of the spine with a sideways curvature. The pressure required inside the TLSO for ideal corrective results remains unclear. Retrofitting TLSOs with commercially available pressure measurement systems is expensive and can only be performed in a laboratory. The aim of this study was to develop a cost-effective but accurate pressure sensor system for TLSOs. The sensor was built from a piezoresistive polymer, placed between two closed-cell foam liners, and evaluated with a material testing machine. Because foams are energy absorbers, the pressure-conductance curve was affected by hysteresis. The sensor was calibrated on a force plate with the transitions from loading to unloading used to establish the calibration curve. The root mean square error was 12% on average within the required pressure range of 0.01–0.13 MPa. The sensor reacted to the changing pressure during breathing and different activities when tested underneath a chest belt at different tensions. The peak pressure reached 0.135 MPa. The sensor was further tested inside the scoliosis brace during different activities. The measured pressure was 0.014–0.124 MPa. The results from this study enable cheaper and mobile systems to be used for clinical studies on the comfort and pressure of braces during daily activities.

Studies on Nanostructured Polyurethane/Clay Interpenetrating Polymer Networks

2005 ◽  
Vol 475-479 ◽  
pp. 1001-1004
Author(s):  
Ninglin Zhou ◽  
Xiao Xian Xia ◽  
Li Li ◽  
Shao Hua Wei ◽  
Jian Shen
Keyword(s):  
Mechanical Properties ◽  
Polymer Networks ◽  
Testing Machine ◽  
Physical And Mechanical Properties ◽  
Interpenetrating Polymer Networks ◽  
Absorption Properties ◽  
Tensile Testing Machine ◽  
Swelling Agent ◽  
Silicate Layers ◽  
Polyurethane Matrix

A novel exfoliated polyurethane (PU)/clay Interpenetrating Polymer Networks (IPNs) nanocomposite has been synthesized with polyurethane and organoclay. MTPAC is used as swelling agent to treat Na-montmorillonite for forming organoclay. The results indicate that there is very good compatibility between organoclay and PU. Nanoscale silicate dispersion was analyzed by XRD. The mechanical properties of the nanocomposites have been measured by tensile testing machine. The nanocomposites show obviously improved physical and mechanical properties when compared with the pure polymer. Additionally, PU /MTPAC- clay shows lower water absorption properties than pure PU do. In addition, the reinforcing and intercalating mechanism of silicate layers in polyurethane matrix are discussed.

A New Stress Sensor Based on Amorphous Alloy for Dynamic Weigh Rail

2011 ◽  
Vol 204-210 ◽  
pp. 608-611
Author(s):  
Yan Ping Shi
Keyword(s):  
Amorphous Alloy ◽  
Testing Machine ◽  
Material Testing ◽  
Static Characteristic ◽  
Stress Sensor ◽  
Actual Experiment ◽  
High Measurement ◽  
Material Testing Machine ◽  
Output Equation

In order to solve some problem of stress sensor in dynamic weigh rail, a new kind of inductive stress sensor based on magnetostriction effect of amorphous alloy was developed. First, the principle of sensor, and inferred its output equation were discussed. Second, the static characteristic experiment and the actual experiment on the material testing machine and the mine haulage rail were separately made. The results of the test have showed that this stress sensor has some characteristics as high measurement sensitiveness and accuracy. Also being simple, convenient and solid to install and use, so it is feasible to apply the sensor for the dynamic weigh rail.

scholarly journals Low-Cost Force Sensors Embedded in Physical Human–Machine Interfaces: Concept, Exemplary Realization on Upper-Body Exoskeleton, and Validation

Sensors ◽  
2022 ◽  
Vol 22 (2) ◽  
pp. 505
Author(s):  
Niclas Hoffmann ◽  
Samet Ersoysal ◽  
Gilbert Prokop ◽  
Matthias Hoefer ◽  
Robert Weidner
Keyword(s):  
Low Cost ◽  
Testing Machine ◽  
Measurement Data ◽  
Upper Body ◽  
Testing Environment ◽  
Physical Support ◽  
Pressure Distributions ◽  
Human Machine Interfaces ◽  
Piezoresistive Pressure Sensor ◽  
Material Testing Machine

In modern times, the collaboration between humans and machines increasingly rises, combining their respective benefits. The direct physical support causes interaction forces in human–machine interfaces, whereas their form determines both the effectiveness and comfort of the collaboration. However, their correct detection requires various sensor characteristics and remains challenging. Thus, this paper presents a developed low-cost sensor pad working with a silicone capsule and a piezoresistive pressure sensor. Its measurement accuracy is validated in both an isolated testing environment and a laboratory study with four test subjects (gender-balanced), and an application integrated in interfaces of an active upper-body exoskeleton. In the material-testing machine, it becomes apparent that the sensor pad generally features the capability of reliably determining normal forces on its surface until a certain threshold. This is also proven in the real application, where the measurement data of three sensor pads spatially embedded in the exoskeletal interface are compared to the data of an installed multi-axis load cell and a high-resolution flexible pressure map. Here, the consideration of three sensor pads potentially enables detection of exoskeletal support on the upper arm as well as “poor” fit conditions such as uneven pressure distributions that recommend immediate system adjustments for ergonomic improvements.

scholarly journals METHOD OF SAMPLE MANUFACTURING FROM MULTILAYER COMPOSITE MATERIALS FOR STUDYING THEIR MECHANICAL PROPERTIES

2018 ◽  
pp. 16-23
Author(s):  
Alsaid Mazen ◽  
Ali Salamekh
Keyword(s):  
Mechanical Properties ◽  
Composite Materials ◽  
Polymer Composite ◽  
Testing Machine ◽  
Physical And Mechanical Properties ◽  
Polymer Composite Materials ◽  
Technological Parameters ◽  
Cutting Out ◽  
Method Of Production ◽  
Economic Considerations

In the last decades there is increasing the need to apply polymer composite materials in different industries, particularly in shipbuilding. There are developing single structures made from polymer composite materials to be used on board ships. The article focuses on technology of manufacturing slabs from polymer composite materials to carry out mechanical testing in the laboratory special standard units. Mechanical properties of polymer composite materials depend on molding technologies. There has been described a technology of sample manufacturing from polymer composite materials reinforced with glass fiber mat with fiberglass plastics. The technique of testing the specified samples for tensile strength has been considered. The sizes and shapes of the samples as well as the technological parameters of the manufacturing process have been validated, depending on the standard requirements and the technological features of the testing machine. The physical and mechanical properties of the components that make up the composite materials are considered. The sequence of stacking layers for preparation of plates from composite materials is indicated. The dimensions of the plates for cutting out finished samples are determined, depending on the method of production. The way of laying plates from composite materials has been chosen on the base of economic considerations and conditions of accessibility. The obtained results of mechanical properties can be used in solving problems of application of polymer composite materials in shipbuilding, for example, in manufacturing superstructures of some dry cargo vessels.

scholarly journals Characterization of Three-Dimensional Printed Composite Scaffolds Prepared with Different Fabrication Methods

2016 ◽  
Vol 61 (2) ◽  
pp. 645-650 ◽  
Author(s):  
K. Szlązak ◽  
J. Jaroszewicz ◽  
B. Ostrowska ◽  
T. Jaroszewicz ◽  
M. Nabiałek ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Fused Deposition Modeling ◽  
Testing Machine ◽  
Three Dimensional ◽  
Gravimetric Analysis ◽  
Solution Casting ◽  
Micro Computed Tomography ◽  
Optimal Method ◽  
Fused Deposition ◽  
Material Testing Machine

Abstract An optimal method for composites preparation as an input to rapid prototyping fabrication of scaffolds with potential application in osteochondral tissue engineering is still needed. Scaffolds in tissue engineering applications play a role of constructs providing appropriate mechanical support with defined porosity to assist regeneration of tissue. The aim of the presented study was to analyze the influence of composite fabrication methods on scaffolds mechanical properties. The evaluation was performed on polycaprolactone (PCL) with 5 wt% beta-tricalcium phosphate (TCP) scaffolds fabricated using fused deposition modeling (FDM). Three different methods of PCL-TCP composite preparation: solution casting, particles milling, extrusion and injection were used to provide material for scaffold fabrication. The obtained scaffolds were investigated by means of scanning electron microscope, x-ray micro computed tomography, thermal gravimetric analysis and static material testing machine. All of the scaffolds had the same geometry (cylinder, 4×6 mm) and fiber orientation (0/60/120°). There were some differences in the TCP distribution and formation of the ceramic agglomerates in the scaffolds. They depended on fabrication method. The use of composites prepared by solution casting method resulted in scaffolds with the best combination of compressive strength (5.7±0.2 MPa) and porosity (48.5±2.7 %), both within the range of trabecular bone.

scholarly journals Compression Characteristics of Solid Wastes as Backfill Materials

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Meng Li ◽  
Jixiong Zhang ◽  
Rui Gao
Keyword(s):  
Large Diameter ◽  
Testing Machine ◽  
Deformation Modulus ◽  
Compression Tests ◽  
Initial Portion ◽  
Filling Materials ◽  
Backfill Materials ◽  
Material Testing Machine ◽  
Compression Characteristics ◽  
The Relationship

A self-made large-diameter compression steel chamber and a SANS material testing machine were chosen to perform a series of compression tests in order to fully understand the compression characteristics of differently graded filling gangue samples. The relationship between the stress-deformation modulus and stress-compression degree was analyzed comparatively. The results showed that, during compression, the deformation modulus of gangue grew linearly with stress, the overall relationship between stress and compression degree was approximately nonlinear, and the deformation of gangue was rather large during the initial portion of the test. Gangue sample mixed with Talbot Formula provides the best deformation resistance capacity, followed by fully graded and single-graded gangue samples. For applications, with adjustment of the gradation of filling materials and optimal design of compacting equipment, surface subsidence may be better controlled.

scholarly journals Effects of Zr, Y on the Microstructure and Properties of As-Cast Cu-0.5Y-xZr (wt.%) Alloys

Metals ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. 1084
Author(s):  
Dong Liang ◽  
Ning Wang ◽  
Yuxiang Wang ◽  
Zhenjie Liu ◽  
Ying Fu
Keyword(s):  
Electron Microscopy ◽  
Mechanical Properties ◽  
Tensile Strength ◽  
Copper Alloys ◽  
Testing Machine ◽  
Elongation Rate ◽  
Nominal Composition ◽  
Microstructure And Properties ◽  
Universal Material Testing Machine ◽  
Material Testing Machine

In this paper, the microstructure and properties of as-cast Cu-Y-Zr alloys with different Zr content were studied in order to investigate whether the precipitates in copper alloys would interact with each other by adding Y and Zr simultaneously. As-cast Cu-0.5Y-xZr (wt.%, x = 0.05 and 0.1, nominal composition) alloys were prepared by vacuum melting in this study. Scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), X-ray diffraction (XRD), and transmission electron microscopy (TEM) were used to observe the microstructure of the alloys. The mechanical properties of the alloys were tested by universal material testing machine at room temperature. The effects of Zr content on the microstructure and mechanical properties of the alloys were explored. As shown by the research results, in the as-cast Cu-0.5Y-xZr (wt.%) alloys, the precipitated phase was the Cu5Y/Cu5Zr phase and ranged from 10 nm to 70 nm in size; when the Zr content increased from 0.05 wt.% to 0.1 wt.%, both the tensile strength and elongation rate of the alloys increased; when the Zr content was 0.1 wt.%, the tensile strength was 225 MPa and the elongation rate was 22.5%.

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