Investigation of Implant Bone Interface with Non-Invasive Methods: Numerical Simulation, Strain Gauges and Optical Coherence Tomography

2008 ◽  
Vol 399 ◽  
pp. 193-198 ◽  
Author(s):  
Sergiu Antonie ◽  
Cosmin Sinescu ◽  
Meda Negrutiu ◽  
Carmen Sticlaru ◽  
Radu Negru ◽  
...  

The quality of the evaluation of implant insertion could be investigated by implant bone interface analysis. In this study the numerical simulation, tensional stamps and optical coherence tomography as a noninvasive method were used in order to evaluate these interfaces. The system contains two interferometers and one scanner. For each incident analysis a stuck made of 61 slices was obtain. These slices were used in order to obtain a 3D model of the implant bone interface. The results obtained point out the existence of gaps between the implant and the bone. In conclusion the optical coherence tomography could be used for implant bone interface investigation.

Author(s):  
Anoop B. N. ◽  
G. N. Girish ◽  
Sudeep P. V. ◽  
Jeny Rajan

Optical coherence tomography (OCT) is a non-invasive imaging technique widely used in ophthalmology. The presence of speckle affects the quality of OCT images. Despeckling is necessary to improve its visual quality, and it is an integral part of software packages used for the computerized analysis of OCT. Even though a few methods for despeckling OCT are available in the literature, a cross-comparison of their performance is not known to be available. In this chapter, the techniques available in the literature for despeckling the OCT images have been identified. The results of the despeckling algorithms are compared both qualitatively and quantitatively by concerning the noise suppression capability and feature preservation. Among the available techniques, iterative adaptive unbiased (IAUB) filter is found to be superior as far as its performance regarding despeckling on retinal OCT images.


2008 ◽  
Author(s):  
Cosmin Sinescu ◽  
Michael Hughes ◽  
Adrian Bradu ◽  
Meda Negrutiu ◽  
Carmen Todea ◽  
...  

Heliyon ◽  
2021 ◽  
Vol 7 (4) ◽  
pp. e06645
Author(s):  
Charlotte Theresa Trebing ◽  
Sinan Sen ◽  
Stefan Rues ◽  
Christopher Herpel ◽  
Maria Schöllhorn ◽  
...  

2021 ◽  
Vol 137 ◽  
pp. 106861
Author(s):  
Deepa Joshi ◽  
Ankit Butola ◽  
Sheetal Raosaheb Kanade ◽  
Dilip K. Prasad ◽  
S.V. Amitha Mithra ◽  
...  

Pharmaceutics ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 217
Author(s):  
Maria Jesus Rodrigo ◽  
Amaya Pérez del Palomar ◽  
Alberto Montolío ◽  
Silvia Mendez-Martinez ◽  
Manuel Subias ◽  
...  

Intravitreal injection is the gold standard therapeutic option for posterior segment pathologies, and long-lasting release is necessary to avoid reinjections. There is no effective intravitreal treatment for glaucoma or other optic neuropathies in daily practice, nor is there a non-invasive method to monitor drug levels in the vitreous. Here we show that a glaucoma treatment combining a hypotensive and neuroprotective intravitreal formulation (IF) of brimonidine–Laponite (BRI/LAP) can be monitored non-invasively using vitreoretinal interface imaging captured with optical coherence tomography (OCT) over 24 weeks of follow-up. Qualitative and quantitative characterisation was achieved by analysing the changes in vitreous (VIT) signal intensity, expressed as a ratio of retinal pigment epithelium (RPE) intensity. Vitreous hyperreflective aggregates mixed in the vitreous and tended to settle on the retinal surface. Relative intensity and aggregate size progressively decreased over 24 weeks in treated rat eyes as the BRI/LAP IF degraded. VIT/RPE relative intensity and total aggregate area correlated with brimonidine levels measured in the eye. The OCT-derived VIT/RPE relative intensity may be a useful and objective marker for non-invasive monitoring of BRI/LAP IF.


Author(s):  
Linda Tognetti ◽  
Andrea. Carraro ◽  
Elisa Cinotti ◽  
Mariano Suppa ◽  
Veronique Marmol ◽  
...  

2021 ◽  
pp. 29-37
Author(s):  
Irina Aleksandrovna Rakitina ◽  
Alfiya Gumyarovna Iskhakova ◽  
Evgeny Andreevich Zamytsky ◽  
Marina Vladimirovna Makolina ◽  
Farida Sagitovna Goleeva ◽  
...  

Optical Coherence Tomography (OCT) is a modern, highly accurate, non-invasive study of various eye structures. OCT is a non-contact method that allows a specialist to visualize eye tissue with a very high resolution (1–15 microns), the accuracy of which is comparable to microscopic examination. The theoretical foundations of the OCT method were developed in 1995 by the American ophthalmologist K. Pulafito, and already in 1996–1997 Carl Zeiss Meditec introduced the first device for optical coherence tomography into clinical practice. Today, OCT devices are used to diagnose various diseases of the fundus and anterior segment of the eye. Due to the maximum accuracy, the method of light scanning greatly simplifies the diagnosis of pathologies of the organs of vision, regardless of the cause of their occurrence and the stage of the course. In terms of information content, the technique is not inferior to histology, but the advantage of OCT is the absence of the risk of injury to the eye tissues [1, 2].


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