Despeckling Algorithms for Optical Coherence Tomography Images

Author(s):  
Anoop B. N. ◽  
G. N. Girish ◽  
Sudeep P. V. ◽  
Jeny Rajan

Optical coherence tomography (OCT) is a non-invasive imaging technique widely used in ophthalmology. The presence of speckle affects the quality of OCT images. Despeckling is necessary to improve its visual quality, and it is an integral part of software packages used for the computerized analysis of OCT. Even though a few methods for despeckling OCT are available in the literature, a cross-comparison of their performance is not known to be available. In this chapter, the techniques available in the literature for despeckling the OCT images have been identified. The results of the despeckling algorithms are compared both qualitatively and quantitatively by concerning the noise suppression capability and feature preservation. Among the available techniques, iterative adaptive unbiased (IAUB) filter is found to be superior as far as its performance regarding despeckling on retinal OCT images.

2009 ◽  
Vol 24 (2) ◽  
pp. 128
Author(s):  
Julia K.S. Gallwas ◽  
Herbert Stepp ◽  
Lisa Turk ◽  
Klaus Friese ◽  
Christian Dannecker

2011 ◽  
Vol 152 (28) ◽  
pp. 1125-1132
Author(s):  
Attila Óvári ◽  
Hans-Wilhelm Pau ◽  
Tino Just

Optical coherence tomography is an imaging technique based on coherence interferometry. It is used in many medical fields due to its non-invasive imaging capabilities with micrometer resolution. The aim of the authors was to review the applicability of the optical coherence tomography in otolaryngology. Literature data and their own studies show that optical coherence tomography is a reliable method for identifying and targeted biopsy of inflammated, pre-malignant or cancer tissue in human laryngeal and pharyngeal mucosa. Another emerging field for optical coherence tomography is diagnosis of middle ear diseases, especially stapes ankylosis and cholesteatoma. Orv. Hetil., 2011, 152, 1125–1132.[Formula: see text]


2008 ◽  
Vol 399 ◽  
pp. 193-198 ◽  
Author(s):  
Sergiu Antonie ◽  
Cosmin Sinescu ◽  
Meda Negrutiu ◽  
Carmen Sticlaru ◽  
Radu Negru ◽  
...  

The quality of the evaluation of implant insertion could be investigated by implant bone interface analysis. In this study the numerical simulation, tensional stamps and optical coherence tomography as a noninvasive method were used in order to evaluate these interfaces. The system contains two interferometers and one scanner. For each incident analysis a stuck made of 61 slices was obtain. These slices were used in order to obtain a 3D model of the implant bone interface. The results obtained point out the existence of gaps between the implant and the bone. In conclusion the optical coherence tomography could be used for implant bone interface investigation.


Heliyon ◽  
2021 ◽  
Vol 7 (4) ◽  
pp. e06645
Author(s):  
Charlotte Theresa Trebing ◽  
Sinan Sen ◽  
Stefan Rues ◽  
Christopher Herpel ◽  
Maria Schöllhorn ◽  
...  

2021 ◽  
Vol 137 ◽  
pp. 106861
Author(s):  
Deepa Joshi ◽  
Ankit Butola ◽  
Sheetal Raosaheb Kanade ◽  
Dilip K. Prasad ◽  
S.V. Amitha Mithra ◽  
...  

Pharmaceutics ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 217
Author(s):  
Maria Jesus Rodrigo ◽  
Amaya Pérez del Palomar ◽  
Alberto Montolío ◽  
Silvia Mendez-Martinez ◽  
Manuel Subias ◽  
...  

Intravitreal injection is the gold standard therapeutic option for posterior segment pathologies, and long-lasting release is necessary to avoid reinjections. There is no effective intravitreal treatment for glaucoma or other optic neuropathies in daily practice, nor is there a non-invasive method to monitor drug levels in the vitreous. Here we show that a glaucoma treatment combining a hypotensive and neuroprotective intravitreal formulation (IF) of brimonidine–Laponite (BRI/LAP) can be monitored non-invasively using vitreoretinal interface imaging captured with optical coherence tomography (OCT) over 24 weeks of follow-up. Qualitative and quantitative characterisation was achieved by analysing the changes in vitreous (VIT) signal intensity, expressed as a ratio of retinal pigment epithelium (RPE) intensity. Vitreous hyperreflective aggregates mixed in the vitreous and tended to settle on the retinal surface. Relative intensity and aggregate size progressively decreased over 24 weeks in treated rat eyes as the BRI/LAP IF degraded. VIT/RPE relative intensity and total aggregate area correlated with brimonidine levels measured in the eye. The OCT-derived VIT/RPE relative intensity may be a useful and objective marker for non-invasive monitoring of BRI/LAP IF.


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