Research and Development of Low-Cost Titanium Alloys for Biomedical Applications

2013 ◽  
Vol 551 ◽  
pp. 133-139 ◽  
Author(s):  
Mitsuo Niinomi ◽  
Masaaki Nakai ◽  
Junko Hieda ◽  
Ken Cho ◽  
Toshikazu Akahori ◽  
...  

β-type titanium alloys comprising low cost elements such as Fe, Mn, Cr, Sn, Al, O and N and having low Young’s modulus are currently being developed. Examples of such alloys include Ti-10Cr-Al, Ti-Mn, Ti-Mn-Fe, Ti-Mn-Al, Ti-Cr-Al, Ti-Sn-Cr, Ti-Cr-Sn-Zr, Ti-(Cr, Mn)-Sn, and Ti-12Cr. Ti-5Fe-3Nb-3Zr belongs to that class of titanium alloys in which rare metals such as Nb, Ta, and Zr have been reduced using Fe. Ti-5Fe-3Nb-3Zr has a Young’s modulus of around 76 GPa and has greater strength than that of Ti-6Al-4V ELI for biomedical applications. The characteristics of Ti-5Fe-3Nb-3Zr and other low-cost beta-type titanium alloys with low Young’s moduli are discussed from the viewpoint of biomedical applications.

2011 ◽  
Vol 2011 ◽  
pp. 1-10 ◽  
Author(s):  
M. Niinomi ◽  
M. Nakai

β-type titanium alloys with low Young's modulus are required to inhibit bone atrophy and enhance bone remodeling for implants used to substitute failed hard tissue. At the same time, these titanium alloys are required to have high static and dynamic strength. On the other hand, metallic biomaterials with variable Young's modulus are required to satisfy the needs of both patients and surgeons, namely, low and high Young's moduli, respectively. In this paper, we have discussed effective methods to improve the static and dynamic strength while maintaining low Young's modulus forβ-type titanium alloys used in biomedical applications. Then, the advantage of low Young's modulus ofβ-type titanium alloys in biomedical applications has been discussed from the perspective of inhibiting bone atrophy and enhancing bone remodeling. Further, we have discussed the development ofβ-type titanium alloys with a self-adjusting Young's modulus for use in removable implants.


2011 ◽  
Vol 197-198 ◽  
pp. 32-35
Author(s):  
Yun Neng Wang ◽  
Yun Qing Ma ◽  
Shui Yuan Yang ◽  
Xu Liang Liu ◽  
Cui Ping Wang ◽  
...  

The effects of Nb addition on microstructures, Young’s moduli, tensile properties of Ti-30Ta-xNb (x = 21, 24, 27, 30, wt. %) alloys were investigated in this study. The results show that dual phases containing β phase and a little α" martensite were observed when x = 21 and 24, whereas single β phase is present when x = 27 and 30. A minimum Young’s modulus of 52.13 GPa was obtained in Ti-30Ta-21Nb alloy. Ti-30Ta-xNb alloys exhibit high strength-to-modulus ratios, showing their great potentials to develop as new candidates for biomedical applications.


2010 ◽  
Vol 654-656 ◽  
pp. 2138-2141 ◽  
Author(s):  
Xiu Song ◽  
Mitsuo Niinomi ◽  
Harumi Tsutsumi ◽  
Toshikazu Akahori ◽  
Masaaki Nakai ◽  
...  

Y2O3 was added to β-type Ti-29Nb-13Ta-4.6Zr (TNTZ) in order to achieve excellent mechanical performance and low Young’s modulus. TNTZ specimens with 0.05%–1.0% Y are all found to be composed of a β phase. Young’s moduli of TNTZ with 0.05–1.0% Y are all maintained low, and are almost the same as that of TNTZ without Y2O3. The grain size of TNTZ with 0.05%–1.0% Y is smaller than that of TNTZ without Y2O3. Moreover, Y2O3 precipitates can prevent the texture movement, and this effect becomes more obvious with an increase in the Y concentration. The tensile strength of TNTZ is successfully improved by adding Y2O3. TNTZ specimens with 0.2% and 1.0% Y exhibit good balance between the tensile strength and the elongation.


2010 ◽  
Vol 638-642 ◽  
pp. 495-500 ◽  
Author(s):  
Toshikazu Akahori ◽  
Mitsuo Niinomi ◽  
Masaaki Nakai ◽  
Harumi Tsutsumi ◽  
Tomokazu Hattori ◽  
...  

A new -type Ti alloy composed of non-toxic and allergy-free elements like Nb, Ta, and Zr, Ti-29Nb-13Ta-4.6Zr alloy (TNTZ) proposed by present authors, has been developed in order to achieve relatively low Young’s modulus and excellent mechanical performance. On the other hand, Zr has been also paid attention as metallic biomaterial for the next generation because of good biocompatibility nearly equal to Ti or a few GPa smaller Young’s modulus as compared to one. In this study, mechanical performances such as tensile properties and Young's modulus of TNTZ subjected to thermo-mechanical treatments or severe deformation, and the mechanical properties and biocompatibility of Zr-Nb system alloys were investigated in order to judge their potential for biomedical applications. Young’s modulus of as-solutionized TNTZ, which is around 63 GPa, is pretty similar to that of as-cold-rolled TNTZ. The Young’s moduli of hot-rolled Ti-6Al-4V ELI alloy are respective around 110 GPa. The Young’s moduli of as-solutionized and as-cold-rolled TNTZ are around a half of those, and are twice as large as that of the cortical bone. The tensile strengths of TNTZ aged after solution treatment and those aged after cold rolling decrease with an increase in the aging temperature, although the elongation shows the reverse trend. The tensile strength of as-cold-rolled TNTZ is improved drastically through severe deformation such as high pressure torsion and shows more than 1000 MPa. Zr-XNb system alloy (X: 5-30mass%) shows the smallest value of Young’s modulus (around 58 GPa) at Nb content of 20mass%. In the case of implantation of the bars made of Zr-XNb system alloys into the lateral femoral condyles of Japanese white rabbits, the tendency of contact between the cancellous bone and the bar becomes remarkably at 24 weeks after the implantation according to increasing with Nb content.


2014 ◽  
Vol 1024 ◽  
pp. 308-311 ◽  
Author(s):  
Abdel Hady Gepreel Mohamed ◽  
Ibrahim Mervat ◽  
Sengo Kobayashi

The low Young's modulus of Ti-alloys is of particular importance for biomedical applications to prevent or reduce the occurrence of stress shielding. This paper shows some ways that are used to produce new Ti-alloys with low Young's modulus for biomedical applications. The different factors that affect the Young's modulus such as the phase's stability, role of alloying elements, plastic deformation, and texturing are discussed. The low-cost and low-Young's modulus Ti-alloys (i.e., alloys composed mainly of the common elements and/or contains a minimum amount of the high-cost rare elements) are also discussed.


Holzforschung ◽  
2002 ◽  
Vol 56 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Ugai Watanabe ◽  
Minoru Fujita ◽  
Misato Norimoto

Summary The relationship between transverse Young's moduli and cell shapes in coniferous early wood was investigated using cell models constructed by two dimensional power spectrum analysis. The calculated values of tangential Young's modulus qualitatively explained the relationship between experimental values and density as well as the difference in experimental values among species. The calculated values of radial Young's modulus for the species having hexagonal cells agreed well with the experimental values, whereas, for the species having square cells, the calculated values were much larger than the experimental values. This result was ascribed to the fact that the bending moment on the radial cell wall of square cell models was calculated to be small. It is suggested that the asymmetrical shape of real wood cells or the behavior of nodes during ell deformation is an important factor in the mechanism of linear elastic deformation of wood cells.


2019 ◽  
Vol 1347 ◽  
pp. 012022
Author(s):  
Shewei Xin ◽  
Jingli Zhang ◽  
Xiaonan Mao ◽  
Yongqing Zhao ◽  
Quan Hong

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