Modelling and Fabrication of 3-D Carbon-MEMS for Dielectrophoretic Manipulation of Micro/Nanoparticles in Fluids

2009 ◽  
Vol 628-629 ◽  
pp. 435-440 ◽  
Author(s):  
Zi Rong Tang ◽  
M.Rizwan Malik ◽  
Tie Lin Shi ◽  
J. Gong ◽  
L. Nie ◽  
...  

Carbon-MEMS (C-MEMS) have emerged as a new category of devices for micro/nano technology with many potential applications. Dielectrophoretic manipulation of micro/nanoparticles with C-MEMS is studied in this paper. Through electric field distribution modeling in carbon electrode array, we analyze the strongest simulation effect results of electric field in three dimensional (3-D) surface plots depicting the magnitude of electric field in various cross sections at different heights above the channel floor for 2, 10, 30 and 50 μm high carbon electrodes. It is represented here that maximum intensity of electric field generates with the equality between the height above the channel floor and the height of the electrodes. Simulation parameters involved are for dielectrophoretic manipulation of micro/nano particles based on 3-D C-MEMS. The advantages of using 3-D C-MEMS electrodes over other techniques of creating high-throughput systems for dielectrophoretic manipulation environment surrounded by micro/nano horizons are: (i) complex microscale 3-D electrodes with high-aspect ratios can easily be shaped and patterned using conventional lithography (ii) carbon has a high window of stability thus allowing application of higher voltages (iii) there is no need for bulk micromachining or patterning electrodes on multiple planes (iv) the distance between electrodes can precisely be controlled through the lithography process. FEMLAB 3.4 Multiphysics Modeling software (COMSOL, Stockholm, Sweden) is used for the modeling of electric fields and one-layer C-MEMS microelectrode array was fabricated with SU-8 photoresist.

2003 ◽  
Vol 773 ◽  
Author(s):  
Shalini Prasad ◽  
Mo Yang ◽  
Xuan Zhang ◽  
Yingchun Ni ◽  
Vladimir Parpura ◽  
...  

AbstractCharacterization of electrical activity of individual neurons is the fundamental step in understanding the functioning of the nervous system. Single cell electrical activity at various stages of cell development is essential to accurately determine in in-vivo conditions the position of a cell based on the procured electrical activity. Understanding memory formation and development translates to changes in the electrical activity of individual neurons. Hence, there is an enormous need to develop novel ways for isolating and positioning individual neurons over single recording sites. To this end, we used a 3x3 multiple microelectrode array system to spatially arrange neurons by applying a gradient AC field. We characterized the electric field distribution inside our test platform by using two dimensiona l finite element modeling (FEM) and determined the location of neurons over the electrode array. Dielectrophoretic AC fields were utilized to separate the neurons from the glial cells and to position the neurons over the electrodes. The neurons were obtained from 0-2-day-old rat (Sprague-Dawley) pups. The technique of using electric fields to achieve single neuron patterning has implications in neural engineering, elucidating a new and simpler method to develop and study neuronal activity as compared to conventional microelectrode array techniques.


2020 ◽  
Author(s):  
Arup Sarkar ◽  
Rajaraman Gopalan

<i>Single-Molecule Magnets have potential applications in several nano-technology applications including in high-dense information storage devices and realization of this potential application lies in enhancing the barrier height for magnetization reversal (U<sub>eff</sub>). Recent literature examples suggest that the maximum values that one can obtain using a ligand field are already accomplished. Here we have explored using a combination of DFT and ab initio CASSCF calculations, the way to enhance the barrier height using an oriented external electric field for top three Single-ion Magnets ([Dy(Py)<sub>5</sub>(O<sup>t</sup>Bu)<sub>2</sub>]<sup>+</sup> (<b>1</b>) and [Er{N(SiMe<sub>3</sub>)<sub>2</sub>}<sub>3</sub>Cl]<sup>-</sup> (<b>2</b>) and [Dy(Cp<sup>Me3</sup>)Cl] (<b>3</b>)). For the first time our study reveals that, for apt molecules, if appropriate direction and value of electric fields are chosen, the barrier height could be enhanced twice that of the limit set by the ligand field. This novel non-chemical-fine tuning approach to modulate the magnetic anisotropy is expected to yield new generation SIMs.</i>


2010 ◽  
Vol 6 (1) ◽  
pp. 31 ◽  
Author(s):  
Cristina Peratta ◽  
Andres Peratta ◽  
Dragan Poljak

The paper introduces a three dimensional multidomainboundary element model of a pregnant woman and foetus for the analysis of exposure to high voltage extremely low frequency electric fields. The definition of the differentphysical and geometrical properties of the relevant tissues is established according to medical information available in existing literature. The model takes into account changes in geometry, body mass, body fat, and overall chemical composition in the body which influence the electrical properties, throughout the different gestational periods. The developed model is used to solve the case of exposure to overhead power transmission lines at different stages of pregnancy including weeks 8, 13, 26 and 38. The results obtained are in line with those published in the earlier works considering different approaches. In addition, a sensitivity analysis involving varying scenarios of conductivity, foetus postures and geometry for each stage is defined and solved. Finally, a correlation between the externally applied electric field and the current density inside the foetus is established and the zones of maximum exposure are identified.


2007 ◽  
Vol 135 (7) ◽  
pp. 2525-2544 ◽  
Author(s):  
Eric C. Bruning ◽  
W. David Rust ◽  
Terry J. Schuur ◽  
Donald R. MacGorman ◽  
Paul R. Krehbiel ◽  
...  

Abstract On 28–29 June 2004 a multicellular thunderstorm west of Oklahoma City, Oklahoma, was probed as part of the Thunderstorm Electrification and Lightning Experiment field program. This study makes use of radar observations from the Norman, Oklahoma, polarimetric Weather Surveillance Radar-1988 Doppler, three-dimensional lightning mapping data from the Oklahoma Lightning Mapping Array (LMA), and balloon-borne vector electric field meter (EFM) measurements. The storm had a low flash rate (30 flashes in 40 min). Four charge regions were inferred from a combination of LMA and EFM data. Lower positive charge near 4 km and midlevel negative charge from 4.5 to 6 km MSL (from 0° to −6.5°C) were generated in and adjacent to a vigorous updraft pulse. Further midlevel negative charge from 4.5 to 6 km MSL and upper positive charge from 6 to 8 km (from −6.5° to −19°C) were generated later in quantity sufficient to initiate lightning as the updraft decayed. A negative screening layer was present near the storm top (8.5 km MSL, −25°C). Initial lightning flashes were between lower positive and midlevel negative charge and started occurring shortly after a cell began lofting hydrometeors into the mixed phase region, where graupel was formed. A leader from the storm’s first flash avoided a region where polarimetric radar suggested wet growth and the resultant absence of noninductive charging of those hydrometeors. Initiation locations of later flashes that propagated into the upper positive charge tracked the descending location of a polarimetric signature of graupel. As the storm decayed, electric fields greater than 160 kV m−1 exceeded the minimum threshold for lightning initiation suggested by the hypothesized runaway breakdown process at 5.5 km MSL, but lightning did not occur. The small spatial extent (≈100 m) of the large electric field may not have been sufficient to allow runaway breakdown to fully develop and initiate lightning.


Author(s):  
Sophie Loire ◽  
Yanting Zhang ◽  
Frederic Bottausci ◽  
Noel C. MacDonald ◽  
Igor Mezic

We present numerical simulations and experiments on dielectrophoretic (DEP) separation and trapping performed in a titanium-based microchannel linear electrode array. The use of electric fields and in particular dielectrophoresis (DEP) have a great potential to help miniaturize and increase the speed of biomedical analysis. Precise control and manipulation of micro/nano/bio particles inside those miniaturized devices depend greatly on our understanding of the phenomena induced by AC electric fields inside microchannels and how we take advantage of them. The studied DEP devices are composed of two parts: the inter-digitated titanium electrodes and the channel. The electrode substrate is constituted of two layers to form 4-phase traveling wave. Each electrode is 20 μm wide and separated from the other by a gap of 20 μm. The channel is 200 μm wide, 50 μm deep and 6 mm long. The device is designed to generate inhomogeneities in electric-field magnitude. This allows positive and negative DEP (p-DEP and n-DEP). Moreover, it can also produce inhomogeneities in electric-field phase, hence authorizing traveling wave DEP (twDEP). It is also capable of inducing two-frequency DEP, in contrast with most of the previous, single-frequency, designs. The advantages of two-frequency DEP were shown by theoretical work (Chang et al. 2003) and permit precise and optimal control of particles movements. We show that fluid flow effects are substantial and can affect the particle motion in a positive (enhanced trapping) and negative (trapping when separation is desired) way. We discuss the effects of AC-electroosmosis, electrothermal and dielectrophoresis combined. We discuss the advantages of two-frequency dielectrophoretic handling of bioparticles. We investigate the limits of particle size that can be accurately controlled.


Author(s):  
Weiyu Liu ◽  
Yukun Ren ◽  
Ye Tao ◽  
Xiaoming Chen ◽  
Qisheng Wu

In this work, we focus on investigating electrothermal flow in a rotating electric field (ROT-ETF), with primary attention paid to the horizontal traveling-wave electrothermal (TWET) vortex induced at the center of the electric field. The frequency-dependent flow profiles in the microdevice are analyzed using different heat transfer models. Accordingly, we address in particular the importance of electrode cooling in ROT-ETF as metal electrodes of high thermal conductivity while substrate material of low heat dissipation capability are employed to develop such microfluidic chips. Under this circumstance, cooling of electrode array due to external natural convection on millimeter-scale electrode pads for external wire connection occurs and makes the internal temperature maxima shift from the electrode plane to a bit of distance right above the cross-shaped interelectrode gaps, giving rise to reversal of flow rotation from a typical repulsion-type to attraction-type induction vortex, which is in good accordance with our experimental observations of co-field TWET streaming at frequencies on the order of reciprocal charge relaxation time of the bulk fluid. These results point out a way to make a correct interpretation of out-of-phase electrothermal streaming behavior, which holds great potential for handing high-conductivity analytes in modern microfluidic systems.


Author(s):  
Yin Ma ◽  
Tong Li ◽  
Jun Yan ◽  
Xiaorong Wang ◽  
Ji Gao ◽  
...  

Electric field assisted combustion is an important means to improve fuel combustion efficiency. This paper conducts extensive research on flame characteristics under different forms and different application methods of electric fields, emission of soot particles and simulation status. Different flame parameter measurement methods will lead to different degrees of error, and perfect numerical simulation can make simple predictions on experimental data. Most of the current numerical simulations are in two dimensions, and it is necessary to develop a complete and accurate three-dimensional model to simulate and predict the characteristics of the flame under an electric field. The emission of soot particles is also affected by the electric field, and reasonable electric field parameters can greatly reduce the emission of soot particles. It is recommended to conduct centralized measurement of different fuels under the electric field under high pressure and temperature conditions, so as to be able to develop a wider and more accurate flame dynamics and chemical model under the electric field.


2011 ◽  
Vol 25 (07) ◽  
pp. 919-925
Author(s):  
YAN SHEN ◽  
ZHIYONG QIU ◽  
SHIGERU TADA

When neutrally buoyant poly alpha olefin particles in corn oil were exposed to a gradient ac electric field generated by a spatially periodic electrode array, these particles experienced the negative dielectrophoresis and instability in all the suspensions of concentration range from 0.01% to 5% (v/v). One critical particle concentration was experimentally determined as 1% (v/v) below which the particles in corn oil were segregated to form island-like structures in the lower electric field regions; and above which, particles only formed straight stripes. The island-like structure was suspended in the lowest electric field area. Specially designed experiments with a suspension of 1.126% (v/v) confirmed that there exists particle instability. Anisotropic properties of electric interactions are responsible for particle instability in all the suspensions of different concentrations and island-like structures were formed only in the dilute suspensions in which the particle instability has enough space to be developed.


2022 ◽  
Author(s):  
Timothy Wilson ◽  
Mark Eberhart

Bond bundles are chemical bonding regions, analogous to Bader atoms, uniquely defined according to the topology of the gradient bundle condensed charge density, itself obtained by a process of infinitesimal partitioning of the three-dimensional charge density into differential zero-flux surface bounded regions. Here we use bond bundle analysis to investigate the response of the charge density to an oriented electric field in general, and the catalytic effect of such a field on Diels-Alder reactions in particular, which in this case is found to catalyze by allowing the transition state valance bond bundle configuration to be achieved earlier along the reaction pathway. Using precise numerical values, we arrive at the conclusion that chemical reactions and electric field catalysis can be understood in terms of intra-atomic charge density redistribution, i.e., that charge shifts within more so than between atoms account for the making and breaking of bonds.


2021 ◽  
Author(s):  
Timothy Wilson ◽  
Mark Eberhart

Bond bundles are chemical bonding regions, analogous to Bader atoms, uniquely defined according to the topology of the gradient bundle condensed charge density, itself obtained by a process of infinitesimal partitioning of the three-dimensional charge density into differential zero-flux surface bounded regions. Here we use bond bundle analysis to investigate the response of the charge density to an oriented electric field in general, and the catalytic effect of such a field on Diels-Alder reactions in particular, which in this case is found to catalyze by allowing the transition state valance bond bundle configuration to be achieved earlier along the reaction pathway. Using precise numerical values, we arrive at the conclusion that chemical reactions and electric field catalysis can be understood in terms of intra-atomic charge density redistribution, i.e., that charge shifts within more so than between atoms account for the making and breaking of bonds.


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