Hydroxyapatite-Collagen Composite Made from Coral and Chicken Claws for Bone Implant Application

2019 ◽  
Vol 966 ◽  
pp. 145-150
Author(s):  
Siswanto ◽  
Dyah Hikmawati ◽  
Aminatun ◽  
Miranda Zamawi Ichsan
Keyword(s):  
Compressive Strength ◽  
Pore Size ◽  
Functional Groups ◽  
Strength Test ◽  
Precipitation Method ◽  
Cytotoxicity Test ◽  
Bone Implant ◽  
Porous Hydroxyapatite ◽  
Collagen Formation ◽  
Compressive Strength Test

Synthesis of porous hydroxyapatite-collagen composites for bone implant applications has been carried out. Hydroxyapatite synthesized from coral by the precipitation method, while Collagen synthesized from chicken claws. Collagen formation was carried out by freeze-dry technique with variations in freezing time of 2, 4 and 6 hours at -80 ° C. The next process was by drying in a lyophilizer. Characterization of samples was carried out using Fourier Transform Infra Red (FTIR), Scanning Electron Microscopy (SEM), compressive strength test and cytotoxicity test with Microtetrazolium (MTT) assay. FTIR results proved that collagen uptake and hydroxyapatite combine chemically. This is indicated by the absorption of functional groups that did not coincide between collagen and hydroxyapatite functional groups with composites. SEM observations showed that the largest pore size was obtained at freezing for 2 hours which was 774 μm and the smallest in freezing for 6 hours was 640 μm. This pore size was an important parameter of the bone implant because it played a role in the osteoinductive process. The composite compressive strength test results for freezing 2 hours, 4 hours and 6 hours respectively was 737 KPa, 842 KPa and 707.7 KPa. The results of the cytotoxicity test with MTT showed the percentage of cell viability above 100%. This means that the Hydroxyapatite-collagen composite is non-toxic. So, the sample formed has qualified as a bone implant candidate.

The Effect of Glutaraldehyde on Hydroxyapatite-Gelatin Composite with Addition of Alendronate for Bone Filler Application

2018 ◽  
Vol 37 ◽  
pp. 107-116 ◽  
Author(s):  
Alfian Pramudita Putra ◽  
Annisa Aulia Rahmah ◽  
Nia Fitriana ◽  
Sayyidati Arristifanniy Rohim ◽  
Miftakhul Jannah ◽  
...  
Keyword(s):  
Compressive Strength ◽  
Crosslinking Agent ◽  
Strength Test ◽  
Osteoporotic Bone ◽  
Cytotoxicity Test ◽  
Health Ministry ◽  
Bone Filler ◽  
Significant Difference ◽  
Compressive Strength Test ◽  
Per Oral

Based on data from Indonesian Health Ministry in 2009, osteoporosis case reached 19,7 % of the populations in Indonesia, especially women in menopause period. The treatment was performed by consuming bisphosphonate drugs per oral which was not effective since the absorption intake of the drug was only less than 55% of the intake dosage. Because of that, the bone filler which also has a function as drug delivery system was developed. The hydroxyapatite-gelatin bone filler with the addition of alendronate was studied. To increase the characteristics of this bone filler, glutaraldehyde was introduced in the composite as a crosslinking agent. The concentration of 0.25%, 0.5%, and 0.75% were used. The bone filler was then characterized based on FTIR test, morphology test, compressive strength test, cytotoxicity test, and degradation test. The FTIR result showed that there was no significant difference between the sample with and without glutaraldehyde since the crosslinking bond of glutaraldehyde and gelatin was C=N bond which also presented in the gelatin. The morphology of the samples depicted a bigger pore size for higher glutaraldehyde concentration which also supported by lower compressive strength. All the samples were non-toxic based on the cytotoxicity test which had cell viability more than 100%. The degradation tests showed that with the presence of glutaraldehyde in the bone filler could maintain its form longer than the bone filler without glutaraldehyde. In conclusion, the presence of glutaraldehyde could increase the characteristics of the hydroxyapatite-gelatin composite with the addition of alendronate as a bone filler candidate for osteoporotic bone.

scholarly journals Properties of Self-curing High Strength Concrete by using Baby Polymer Diapers

2018 ◽  
Vol 203 ◽  
pp. 06022
Author(s):  
Salmia Beddu ◽  
Daud Mohamad ◽  
Fadzli Mohamed Nazri ◽  
Siti Nabihah Sadon ◽  
Mohamed Galal Elshawesh
Keyword(s):  
Compressive Strength ◽  
High Strength Concrete ◽  
Drying Shrinkage ◽  
High Strength ◽  
Strength Test ◽  
Curing Process ◽  
Compressive Strength Test ◽  
Mechanical And Physical Properties ◽  
Compressive Strength Of Concrete ◽  
Strength And Durability

This study investigates the self-curing concrete using baby polymer diapers as substitute method of curing process in order to improve mechanical and physical properties of concrete. Three different proportion of baby polymer diapers which are 1%, 3% and 5% were mix with concrete. Slump, compressive strength and drying shrinkage test were performed in order to study the workability, strength and durability of the concrete. All concrete were tested for 1, 3, 7, 14, and 28 days for drying shrinkage test. Meanwhile, all concrete were test at 3, 7 and 28 days for compressive strength test. Compressive strength of concrete containing 5% baby polymer diapers show the highest strength at 28 days compared to others percentage. Thus, it indicates that application of baby polymer diaper as self-cure agent can improve the concrete performances.

scholarly journals Effect of Mound Soil on Concrete Produced with River Sand

2014 ◽  
Vol 2 (1) ◽  
pp. 75-82
Author(s):  
Elivs M. Mbadike ◽  
N.N Osadebe
Keyword(s):  
Compressive Strength ◽  
Research Work ◽  
Strength Test ◽  
Control Test ◽  
River Sand ◽  
Cement Ratio ◽  
Water Cement Ratio ◽  
Compressive Strength Test ◽  
Average Compressive Strength

In this research work, the effect of mound soil on concrete produced with river sand was investigated. A mixed proportion of 1.1.8:3.7 with water cement ratio of 0.47 were used. The percentage replacement of river sand with mound soil is 0%, 5%, 10%, 20%, 30% and 40%. Concrete cubes of 150mm x 150mm x150mm of river sand/mound soil were cast and cured at 3, 7, 28, 60 and 90 days respectively. At the end of each hydration period, the three cubes for each hydration period were crushed and their average compressive strength recorded. A total of ninety (90) concrete cubes were cast. The result of the compressive strength test for 5- 40% replacement of river sand with mound soil ranges from 24.00 -42.58N/mm2 a against 23.29-36.08N/mm2 for the control test (0% replacement).The workability of concrete produced with 5- 40% replacement of river sand with mound soil ranges from 47- 62mm as against 70mm for the control test.

scholarly journals Analysis of The Rock Fracture on Uniaxial Compressive Strength Test

2021 ◽  
Vol 2 (1) ◽  
Author(s):  
Edward Dinoy ◽  
Yohanes Gilbert Tampaty ◽  
Imelda Srilestari Mabuat ◽  
Joseph Alexon Sutiray Dwene
Keyword(s):  
Compressive Strength ◽  
Uniaxial Compressive Strength ◽  
Poisson Ratio ◽  
Rock Fracture ◽  
Strength Test ◽  
Maximum Pressure ◽  
Test Results ◽  
Average Value ◽  
Compressive Strength Test ◽  
Uniaxial Compressive Strength Test

The compressive strength test is one of the technical properties or compressive strength tests that are commonly used in rock mechanics to determine the collapse point or the elasticity of rock against maximum pressure. The rock collapse point is a measure of the strength of the rock itself when the rock is no longer able to maintain its elastic properties. The purpose of this test is to find out how long the rock maintains its strength or elasticity properties when pressure is applied, and to find out the difference between the strength of compact rock and rock that has fractures when pressure is applied. Rocks that have fractures will break more easily or quickly when pressure is applied compared to compact rocks. This analysis is carried out by comparing the rock strength of each sample, both those that have fractures and compact rocks. To find out these differences, laboratory testing was carried out. The test results show the value (compressive strength test 57.76 MPa), (elastic modulus 5250.000MPa), (Poisson ratio 0.05) and the average value of rock mechanical properties test (axial 0.91), (lateral-0.279), and (volumetric 0.252) . Based on the test results above, it shows that rocks that have fractures will break more easily when pressure is applied, compared to compact rocks that have a long time in the uniaxial compressive strength test.

scholarly journals Effect of fine recycled aggregates on the properties of non-cement blended materials

2020 ◽  
Vol 323 ◽  
pp. 01018
Author(s):  
Wei-Ting Lin ◽  
Lukáš Fiala ◽  
An Cheng ◽  
Michaela Petříková
Keyword(s):  
Compressive Strength ◽  
Blast Furnace Slag ◽  
Interface Structure ◽  
Strength Test ◽  
Recycled Aggregates ◽  
Test Results ◽  
Granulated Blast Furnace Slag ◽  
Fine Aggregates ◽  
Compressive Strength Test ◽  
Furnace Slag

In this study, the different proportions of co-fired fly ash and ground granulated blast-furnace slag were used to fully replace the cement as non-cement blended materials in a fixed water-cement ratio. The recycled fine aggregates were replaced with natural fine aggregates as 10%, 20%, 30%, 40% and 50%. The flowability, compressive strength, water absorption and scanning electron microscope observations were used as the engineered indices by adding different proportions of recycled fine aggregates. The test results indicated that the fluidity cannot be measured normally due to the increase in the proportion of recycled fine aggregates due to its higher absorbability. In the compressive strength test, the compressive strength decreased accordingly as the recycled fine aggregates increased due to the interface structure and the performance of recycled aggregates. The fine aggregates and other blended materials had poor cementation properties, resulting in a tendency for their compressive strength to decrease. However, the compressive strength can be controlled above 35 MPa of the green non-cement blended materials containing 20% recycled aggregates.

scholarly journals PENGARUH PENGGUNAAN LIMBAH PLASTIK POLYPROPYLENE (PP) SEBAGAI CAMPURAN AGREGAT KASAR TERHADAP KUAT TEKAN DAN TARIK PADA BETON FC’ 25 MPA

2019 ◽  
Vol 3 (2) ◽  
pp. 81-89
Author(s):  
Angga Pirman Firdaus ◽  
Jonbi
Keyword(s):  
Tensile Strength ◽  
Compressive Strength ◽  
Strength Test ◽  
Plastic Waste ◽  
Concrete Mixture ◽  
Strength Testing ◽  
Concrete Compressive Strength ◽  
Tensile Strength Test ◽  
Compressive Strength Test ◽  
Waste Mixture

Indonesia ranks second in the world's largest plastic waste producer after China. Each year, Indonesia can contributeup to 187.2 million tons of plastic waste, while China reaches 262.9 million tons of plastic waste. Based on the data, one way to utilize plastic waste by using plastic waste as a mixture of concrete, where the plastic used is polypropylene (PP) plastic with different percentage of concrete mixture, the test includes compressive strength test and tensile concrete. The results of concrete compressive strength testing with polypropylene (PP) plastic waste mixture of 5%, 10% and 15% at age 28 in aggregate aggregate mixture decreased by 5.15%, 6.89% and 13.53%. As for the result of concrete tensile strength test with polypropylene (PP) plastic waste mixture of 5%, 10% and 15% at age 28 in crude aggregate mixture decreased 17,61%, 24,13% dan 23,24%.

The Effect of Different Curing Conditions on Compressive Strength of Concrete

2017 ◽  
Vol 60 (3) ◽  
pp. 147-153
Author(s):  
Muhammad Arslan ◽  
Muhammad Asif Saleem ◽  
Maria Yaqub ◽  
Muhammad Saleem Khan
Keyword(s):  
Compressive Strength ◽  
Research Work ◽  
Concrete Structures ◽  
Strength Test ◽  
The Other ◽  
Cylindrical Shape ◽  
Curing Conditions ◽  
Compressive Strength Test ◽  
Different Types ◽  
Compressive Strength Of Concrete

The focus of this research work was to analyse the effect of different types of curing oncompressive strength of concrete structures. For this purpose, 54 test specimens of cylindrical shape wereprepared. These specimens were cured with different methods and were tested on different age days toanalyse the effect of curing on compressive strength. Test specimens cured with conventional water curingmethod gives the highest results as compared to the other adopted methods.

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