RATG: implications for nursing care in organ transplantation

1990 ◽  
Vol 10 (9) ◽  
pp. 18-19
Author(s):  
JL Pezze

Proper immunosuppression is a key element determining the survival of patients undergoing organ transplantation. RATG is one of several immunosuppressive agents available for use. Nurses need to recognize the unique challenges that RATG poses for patient and dosage preparation, along with those affecting its administration and post administration. Doing so can effectively aid the transplanted patient in achieving optimal immunosuppression with the least amount of unpleasant effects. The hospital stay for a transplant patient can be very frustrating and exhausting. Nursing interventions that limit these effects can foster a more desirable patient experience.

2008 ◽  
Vol 18 (6) ◽  
pp. 1376-1380 ◽  
Author(s):  
X. Tao ◽  
J. J. Kavanagh

Long-term risk of gynecological malignancies in organ transplantation patients has increased compared with that of the general population owing to the use of immunosuppressive agents. Treatment, especially chemotherapy, in these patients should take into consideration their renal function and the effects of immunosuppressive agents. We here present two case reports of patients with chemotherapy-treated gynecological malignancies who had previously received organ transplantation. The first case, a rare occurrence of simultaneous carcinomas of the uterine corpus and ovary, is the first such report in the English literature describing chemotherapy for concurrent serous papillary ovarian carcinoma and endometrioid endometrial carcinoma in a renal transplant patient. The second case report, describing chemotherapy for cervical cancer following two organ transplantation, also rare, is the first such report in the English literature and the first report of cervical cancer after heart–kidney transplantation.


Impact ◽  
2020 ◽  
Vol 2020 (7) ◽  
pp. 45-47
Author(s):  
Naoko Fujii

The majority of human beings will be admitted to hospital at some point over the course of their lives. For the more fortunate among us, these hospital stays will be brief and will barely register as a significant experience. However, for others, being admitted for weeks or months at a time will be necessary in order to combat and recover from whatever it was that made admittance to hospital necessary. While it is easy to think of many reasons why a prolonged hospital stay might be undesirable, one that may escape our attention is the clothes that are worn by patients during their stay. Once a patient has been assigned a bed, they are often given a gown which they put on without thought and then lie down. The gowns that are given to patients are generally designed with healthcare professionals in mind. For example, in Japan pyjamas and yukata (bathrobes) are used as hospital gowns because they have a front opening that is easy to use during treatment and nursing care. In addition, the other gowns can be opened from the ankle to the crotch using the zip. Dr Naoko Fujii has focused her career on designing clothes for hospital patients and believes that there is a way to satisfy the practical needs of a hospital and the care it gives at the same time as satisfying the requirements of patients. She is now focusing her attention on this challenge.


2020 ◽  
Vol 11 (9) ◽  
pp. 426-431
Author(s):  
Emily Hooper

The patient was presented to a veterinary hospital with acute progressive onset of non-ambulatory tetraparesis. An appropriate diagnosis of acute idiopathic polyradiculoneuritis was made and suitable supportive nursing care implemented. The patient was later diagnosed with pneumonia as a consequence of prolonged recumbency, requiring further nursing interventions. Treatment with intravenous human immunoglobulin therapy was subsequently initiated and the patient improved but was sadly later euthanased.


2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Ann Flanagan Petry

Remember what drew you to health care? And what makes your work meaningful now? Chances are caring for people is the answer to both questions. In fact, healthcare is provided through relationships. Over a decade ago we developed a care delivery framework described in the award-winning book Relationship-Based Care: A Model for Transforming Practice. We were on the vanguard of a revolution toward more patient-centered caring. Indeed, we have always known the importance of connection to patient experience, employee attitudes, interpersonal relations, teams and performance. For nurses, caring relationships are so essential at work that it is inseparable from the work itself. We believe the best nursing care requires understanding of three key relationships: A. Relationship to one’s self, B. Relationship to co-workers and C. Relationship to patients and families. And, the hallmark of meaningful connection is attunement or tuning-in to others with genuine interest and care.


2018 ◽  
Vol 12 (12) ◽  
pp. 3436 ◽  
Author(s):  
Rafaella Vezzoli da Silva Marques ◽  
Vera Lucia Freitas

RESUMOObjetivo: descrever a importância da assistência de Enfermagem ao paciente transplantado renal. Método: trata-se de um estudo bibliográfico, tipo revisão integrativa, na base de dados LILACS e bibliotecas virtuais SciELO e BVS, incluindo artigos completos, em português, inglês ou espanhol. Estabeleceu-se, um período de 15 anos para a inclusão dos estudos, e os resultados apresentam-se em figuras. Resultados: encontraram-se 1114 artigos, dos quais, após a leitura dos títulos e dos resumos e a aplicação dos critérios de inclusão e exclusão, foram selecionados dez, sendo dois na SciELO, três na BVS e quatro na LILACS. Verifica-se que os artigos abordam, de forma significativa, a relação dos diagnósticos de Enfermagem na elaboração de intervenções adequadas ao paciente. Conclusão: conclui-se que a Enfermagem possui um papel fundamental no sucesso, na recuperação e na melhoria da qualidade de vida do paciente transplantado renal. Descritores: Assistência ao Paciente; Cuidados de Enfermagem; Nefropatias; Pacientes; Sobrevida; Transplante de Rim.ABSTRACT Objective: to describe the importance of nursing care to the renal transplant patient. Method: this is a bibliographical study, type integrative, in the LILACS database and virtual libraries SciELO and VHL, including complete articles, in Portuguese, English or Spanish. A period of 15 years for the inclusion of the studies was established, and the results are presented in figures. Results: 1114 articles were found, of which, after reading titles and abstracts and applying the inclusion and exclusion criteria, ten were selected, two in SciELO, three in VHL and four in LILACS. It is verified that the articles approach, in a significant way, the relation of Nursing diagnoses in the elaboration of adequate interventions to the patient. Conclusion: it is concluded that Nursing plays a fundamental role in the success, recovery and improvement of the quality of life of the renal transplant patient. Descriptors: Patient Care; Nursing Care; Kidney Diseases; Patients; Survival; Kidney Transplantation.RESUMEN Objetivo: describir la importancia de la asistencia de enfermería al paciente trasplantado renal. Método: se trata de un estudio bibliográfico, revisión integrada de tipo, la base de datos LILACS y SciELO bibliotecas virtuales y BVS, incluyendo los artículos completos en portugués, inglés o español. Se estableció, un período de 15 años para la inclusión de los estudios, y los resultados se presentan en figuras. Resultados: se encontraron 1114 artículos, de los cuales, después de la lectura de los títulos y de los resúmenes y la aplicación de los criterios de inclusión y exclusión, fueron seleccionados diez, siendo dos en la SciELO, tres en la BVS y cuatro en la LILACS. Se verifica que los artículos abordan de forma significativa la relación de los diagnósticos de Enfermería en la elaboración de intervenciones adecuadas al paciente. Conclusión: se concluye que la Enfermería tiene un papel fundamental en el éxito, la recuperación y la mejora de la calidad de vida del paciente trasplantado renal. Descriptores: Atención al Paciente; Atención de Enfermería;  Enfermedades Renales; Pacientes; Supervivencia; Trasplante de Riñón.


2005 ◽  
Vol 133 (Suppl. 1) ◽  
pp. 67-73 ◽  
Author(s):  
Leposava Grbovic ◽  
Miroslav Radenkovic

Pharmacotherapy of autoimmune thyroid disease (AITD) is complex. Apart from the replacement hormone therapy, antithyroid agents, beta adrenoceptor blockers and other drugs, in regard to the present symptoms, it also includes the administration of glucocorticoids and immunosuppressive agents. Physiological actions of glucocorticoids are significant in number, well known and described in details. The most prominent pharmacological properties of glucocorticoids, that are important for their clinical use, are antiinflammatory and immunosuppressive actions. In this article, the most notable clinical pharmacology aspects of glucocorticoids have been presented, including the basic principles of their therapeutic use, as well as the most important indications with the examples of dosing regiments (rheumatic disorders, renal diseases, allergic reactions, bronchial asthma, gastrointestinal inflammatory diseases, thrombocytopenia, organ transplantation, and Graves? ophthalmopathy). In addition, adverse and toxic effects of glucocorticoids as well as their interactions with other drugs have been described. Immunosuppressive agents have important role in treatment of immune disorders, including the reduction of immune response in autoimmune diseases and organ transplantation. Apart from glucocorticoids, immunosuppressive agents consist of calcineurin inhibitors (cyclosporine, tacrolimus), antiproliferative and antimetabolic agents (sirolimus, azathioprine, mycophenolate mofetil, methotrexate, cyclophosphamide), monoclonal antibodies: anti-CD3 antibody (muromonab-CD3), anti- CD25 antibody (daclizumab), anti-TNF-alpha antibody (infliximab). In this part, the most updated facts about mechanism of action, rational therapeutic use, as well as adverse and toxic effects of immunosuppressive agents have been reviewed.


Author(s):  
Aline Barbosa Soares ◽  
Débora Rita Gobbi ◽  
André Moreno Silva ◽  
Gisele Duarte da Silva ◽  
Isabel Cristina Gomes Leite de Siqueira ◽  
...  

Anemia Falciforme é uma doença autossômica recessiva com elevada prevalência e morbimortalidade no Brasil. Apresenta uma variedade de complicações que se manifestam de forma peculiar em cada paciente, principalmente na infância e na adolescência. Levantar os diagnósticos e intervenções de enfermagem mais relevantes às crianças e aos adolescentes portadores da doença para proporcionar uma melhor qualidade de vida. Realizou-se o levantamento bibliográfico sobre o tema nas bases de dados SciELO, LILACS e AAFESP, além de dados sobre mortalidade da doença no portal DATASUS. Em 2008, 38,6% das mortes por Anemia Falciforme no Brasil compreendeu a faixa etária entre 0 e 19 anos, evidenciando a necessidade de uma assistência de enfermagem específica, baseada na prevenção e no tratamento das principais complicações da doença. O preparo do enfermeiro é fundamental para individualizar essa assistência junto às crianças e adolescentes portadores da doença para que se obtenha sucesso na prevenção das crises e no tratamento para amenizar os sintomas.Descritores: Enfermagem, Anemia Falciforme, Crianças e Adolescentes. Nursing care in children and adolescents with sickle cell anemiaAbstract: Sickle cell anemia is an autosomal recessive disease with a high prevalence, morbidity and mortality in Brazil. Features a variety of complications that manifest in a peculiar way in each patient, especially in childhood and adolescence. Raise the diagnoses and nursing interventions most relevant to children and adolescents with the disease to provide a better quality of life. We carried out the literature on the subject in the databases SciELO, LILACS and AAFESP, plus data on mortality rates in DATASUS portal. In 2008, 38.6% of deaths from sickle cell disease in Brazil comprised the age group between 0 and 19 years, highlighting the need for specific nursing care based on prevention and treatment of major complications of the disease. The preparation of nurses is critical to individualize this intervention with children and adolescents with the disease in order to achieve success in crisis prevention and treatment to alleviate the symptoms.Descriptors: Nursing, Sickle Cell Anemia, Children and Adolescents. Enfermería de atención a la infancia y la adolescencia con anemia de células falciformesResumen: La anemia falciforme es una enfermedad autosómica recesiva, con una alta prevalencia, morbilidad y mortalidad en Brasil. Cuenta con una variedad de complicaciones que se manifiestan de una manera peculiar en cada paciente, especialmente en la infancia y la adolescencia. Elevar los diagnósticos e intervenciones de enfermería más relacionados con los niños y adolescentes con la enfermedad de proporcionar una mejor calidad de vida. Hemos llevado a cabo la literatura sobre el tema en la bases de datos SciELO, LILACS y AAFESP, además de datos sobre las tasas de mortalidad en DATASUS portal. En 2008, el 38,6% de las muertes por la enfermedad de células falciformes en Brasil comprende el grupo de edad entre 0 y 19 años, destacando la necesidad de cuidados de enfermería específicos basados en la prevención y tratamiento de las principales complicaciones de la enfermedad. La preparación de las enfermeras es fundamental para individualizar la intervención con niños y adolescentes que padecen la enfermedad con el fin de lograr el éxito en la prevención de crisis y el tratamiento para aliviar los síntomas.Descriptores: Enfermería, Anemia de Células Falciformes, la Niñez y la Adolescencia.


Author(s):  
Nathália da Silva Pimentel Reis ◽  
Camilla da Silva Dias ◽  
Valéria de Oliveira Monteiro ◽  
Carla Tatiana Garcia Barreto ◽  
Raíla de Souza Santos ◽  
...  

Objectives: The study’s purpose has been to build Standard Operating Procedures (SOPs) for nursing care while performing diagnostic exams in secondary health care. Methods: A committee for Nursing Care Systematization (NCS) was then established, which assessed the sectors in which new diagnostic technologies were being implemented and raised the need for training of the technical team that performed these tests to standardize procedures, then reducing errors and failures in its realization. The SOPs were described through tables comprised by the following: definition of the diagnostic procedure, necessary material, nursing interventions and special care. Results: Four SOPs were elaborated, related to the exams of spirometry, polysomnography, retinography and hydrogen breath test. Conclusion: It was possible not only to know the execution of the exams, but also to understand the applicability of NCS with a focus on diagnostic technologies, besides providing subsidies for future implementation of NCS in the study institution.


2021 ◽  
Vol 11 ◽  
Author(s):  
Manuel Alfredo Podestà ◽  
Giuseppe Remuzzi ◽  
Federica Casiraghi

Transplantation is the gold-standard treatment for the failure of several solid organs, including the kidneys, liver, heart, lung and small bowel. The use of tailored immunosuppressive agents has improved graft and patient survival remarkably in early post-transplant stages, but long-term outcomes are frequently unsatisfactory due to the development of chronic graft rejection, which ultimately leads to transplant failure. Moreover, prolonged immunosuppression entails severe side effects that severely impact patient survival and quality of life. The achievement of tolerance, i.e., stable graft function without the need for immunosuppression, is considered the Holy Grail of the field of solid organ transplantation. However, spontaneous tolerance in solid allograft recipients is a rare and unpredictable event. Several strategies that include peri-transplant administration of non-hematopoietic immunomodulatory cells can safely and effectively induce tolerance in pre-clinical models of solid organ transplantation. Mesenchymal stromal cells (MSC), non-hematopoietic cells that can be obtained from several adult and fetal tissues, are among the most promising candidates. In this review, we will focus on current pre-clinical evidence of the immunomodulatory effect of MSC in solid organ transplantation, and discuss the available evidence of their safety and efficacy in clinical trials.


Surgery Today ◽  
1997 ◽  
Vol 27 (10) ◽  
pp. 883-891
Author(s):  
Takenori Ochiai ◽  
Kaichi Isono

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