Mechanical reliability of ceramic packages for active implantable medical devices - The IEC hammer test

2014 ◽  
Vol 2014 (1) ◽  
pp. 000319-000324 ◽  
Author(s):  
F. Kohler ◽  
T. Stieglitz ◽  
M. Schuettler
Keyword(s):  
Medical Devices ◽  
High Stress ◽  
Axially Symmetric ◽  
Protective Material ◽  
Implantable Medical Devices ◽  
Mechanical Impact ◽  
Event Simulation ◽  
Laboratory Setup ◽  
Computer Interfaces ◽  
The Impact

Implantable neural prostheses have to fulfill manifold requirements, from the technological side as well as legally. One particular normative demand for active implantable medical devices (AIMDs) which are intended to be implanted in the skull, is withstanding a mechanical impact of 2.5 J, defined by BS EN 45502-2-3:2010 and IEC 60068-2-75:1997. This article shows two computational approaches based on finite element modeling to evaluate the influence of geometrical variations on a brain-computer interfaces' mechanical package stability and the likelihood of withstanding mechanical impact. The presence of a fillet at inner edges (>0.5 mm) as well as a minimum wall thickness of 1 mm could be identified as a mandatory design requirements for axially symmetric packages to avoid extensively high stress levels. Mechanical event simulation (MES) predicted a passing of the hammer test if additional protective material (silicone rubber) is used. This however is postulated by the EN 45502-2-3 standard. The computational findings could be confirmed in a laboratory setup of the impact test.

Formulation and Characterization of Thermoplastic Polyurethane-Based Steroid Eluting Devices

2019 ◽  
Author(s):  
Jessica Doan ◽  
Peter Phommahaxay ◽  
Sarah Olson ◽  
Matthew A. Petersen
Keyword(s):  
Drug Release ◽  
Medical Devices ◽  
Thermoplastic Polyurethane ◽  
Release Behavior ◽  
Implantable Medical Devices ◽  
Industry Standard ◽  
Rapid Characterization ◽  
The Impact ◽  
Standard Components

We describe the formulation and manufacture of thermoplastic polyurethane (TPU)-based steroid-eluting components and the development of a versatile, material-agnostic analytical method for their rapid characterization. The impact of materials, formulation, and processing on controlled release behavior was characterized and compared to current industry standard components under physiologically relevant conditions. The combination of factors modulated drug release, offering new avenues for controlling the release of steroids from implantable medical devices.

Iodinated poly(p-dioxanone) as a facile platform for X-ray imaging of resorbable implantable medical devices

2020 ◽  
Vol 35 (1) ◽  
pp. 39-48
Author(s):  
Fan Zhao ◽  
Haiyan Xu ◽  
Wen Xue ◽  
Yan Li ◽  
Jing Sun ◽  
...  
Keyword(s):  
Medical Devices ◽  
Melt Spinning ◽  
Imaging Techniques ◽  
Fibrous Materials ◽  
Hybrid Fibers ◽  
Implantable Medical Devices ◽  
X Ray ◽  
The Impact

Currently, implantable fibrous medical devices still suffer from invisibility under current clinical imaging techniques. To address this problem, 2, 3, 5-triiodobenzoic acid (TIBA) was recruited as a contrast agent, and then a set of iodinated poly( p-dioxanone) (PPDO) fibers was fabricated via melt-spinning hybrid blends of PPDO with TIBA (PPDO/TIBA). The impact of TIBA content on the rheological behavior of blends was evaluated firstly. The physical, chemical, and thermal properties of PPDO/TIBA fibers were investigated accordingly by SEM, FTIR, DSC, and TGA. Moreover, the radiopaque property of PPDO/TIBA hybrid fibers as a potential radio-opacifying platform for medical devices was verified in vitro and in vivo. Finally, the accumulated release results of the hybrid fibers during in vitro degradation indicate the continual X-ray visibility of the hybrid fibers maintains for 22 days. This intriguing iodinated platform may pave the way for constructing fibrous materials with in-situ X-ray tracking property.

scholarly journals On the review of electronic technologies applied to implantable medical devices

2021 ◽  
Author(s):  
Ronny García-Ramírez ◽  
Gabriel Madrigal-Boza ◽  
Edgar Solera-Bolaños ◽  
Muhammad Ali Siddiqi ◽  
Christos Strydis ◽  
...  
Keyword(s):  
Medical Devices ◽  
Scientific Community ◽  
Heterogeneous Systems ◽  
Point Of View ◽  
Proof Of Concept ◽  
Implantable Medical Devices ◽  
Heart Arrhythmia ◽  
Sql Database ◽  
The Impact ◽  
Electronic Technologies

The development of electronic implantable medical devices (IMD) has been increasing over the years, targeting very diverse applications and implementing different technologies. The impact of IMDs in the treatment of different ailments like Parkinson’s disease, hearing impairment, heart arrhythmia, and chronic pain, among many others, has been notorious and inspired their exploration to treat other health problems. Even when there is great interest in the scientific community for the exploration and development of IMDs, no standards are ruling its development. This lack of standardization is the reason why the analysis of the tendencies of this area from the technical point of view becomes complex. The analysis of the tendencies in the development of IMD devices required the exploration of diverse sources, which describe heterogeneous systems using very different approaches and methodologies for similar problems. In this paper an open SQL database intended for collecting information from IMD publications is presented; at this point, more than 200 published works are feed in the database covering a period from 1974 to 2018. This database is extensible and enables researchers to find trends and explore the development of IMDs from a broader perspective. We also used this database as a proof of concept to explore some general trends in the design of  IMDs based on the included works.

Воздействиеультразвуковогополянадинамическуювязкостьводы

2019 ◽  
pp. 27-29
Author(s):  
P. Vikulin ◽  
K. Khlopov ◽  
M. Cherkashin
Keyword(s):  
Dynamic Viscosity ◽  
Experimental Studies ◽  
Ultrasonic Field ◽  
Maximum Effect ◽  
Ultrasonic Frequency ◽  
Ultrasonic Vibrations ◽  
Wastewater Disposal ◽  
Laboratory Setup ◽  
Sonic Treatment ◽  
The Impact

Enhancing water purification processes is provided by various methods including physical ones, in particular, exposure to ultrasonic vibrations. The change in the dynamic viscosity of water affects the rate of deposition of particles in the aquatic environment which can be used in natural and wastewater treatment. At the Department Water Supply and Wastewater Disposal of the National Research Moscow State University of Civil Engineering experimental studies were conducted under laboratory conditions to study the effect of ultrasound on the change in the dynamic viscosity of water. A laboratory setup has been designed consisting of an ultrasonic frequency generator of the relative intensity, a transducer (concentrator) that transmits ultrasonic vibrations to the source water, and sonic treatment tanks. Experimental studies on the impact of the ultrasonic field in the cavitation mode on the dynamic viscosity of the aqueous medium were carried out the exposure time was obtained to achieve the maximum effect.Интенсификация процессов очистки воды осуществляется с помощью различных методов, в том числе и физических, в частности воздействием ультразвуковых колебаний. Изменение динамической вязкости воды влияет на скорость осаждения частиц в водной среде, что может быть использовано в процессах очистки природных и сточных вод. На кафедре Водоснабжение и водоотведение Национального исследовательского Московского государственного строительного университета в лабораторных условиях проведены экспериментальные исследования по изучению влияния ультразвука на изменение динамической вязкости воды. Разработана схема лабораторной установки, состоящая из генератора ультразвуковых частот с соответствующей интенсивностью, преобразователя (концентратора), передающего ультразвуковые колебания в исходную воду, и емкости для озвучивания. Выполнены экспериментальные исследования по влиянию ультразвукового поля в режиме кавитации на динамическую вязкость водной среды, получено время экспозиции для достижения максимального эффекта.

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