scholarly journals Glycated hemoglobin and red blood cell indices in non-diabetic pregnant women

2017 ◽  
Vol 7 (4) ◽  
Author(s):  
Awad-Elkareem Abass ◽  
Imad R. Musa ◽  
Duria A. Rayis ◽  
Ishag Adam ◽  
Gasim I. Gasim

Hemoglobin A1c (HbA1c) is affected by the red blood cell (RBC) lifespan. The association of HbA1c with RBC indices in pregnant women is not widely investigated. In this study, we investigated the association between HbA1c and Hb/RBCs count and RBCs indices; specifically, Hb/RBCs count and indices in non- diabetic pregnant women. Across-sectional study was carried- out at the antenatal care of Saad Abu Elela Hospital, Khartoum, Sudan. Obstetrics history was gathered using questionnaire and body mass index was calculated. Fasting blood sugar, at one hour, at two hours post prandial and HbA1c were investigated. Complete blood count parameters of RBCs count was performed, including, hematocrit, Hb, RBCs indices of MCV, MCH, and MCHC. One hundred twenty three women were enrolled. The mean age of the participants was 28±5.6 years and a mean body mass index was 27.65±6.8 k/m<sup>2</sup>. There was significant positive correlation between HbA1c and Hb (r=0.174, P=0.037), Hct (r=0.174, P=0.037), and MCHC (r=0.180, P=0.031). A negative correlation between HbA1c and the platelet index PDW (r= –0.198, P=0.017) was documented. The rest of the other factors showed no correlation with HbA1c. In linear regression analysis, HbA1c correlated positively with Hb (P=0.044) and Hct (P=0.047). The present study shows a significant positive correlation between HbA1c value with Hb, Hct, and MCHC. No significant correlation between HbA1c and other RBCs parameters was observed.

2020 ◽  
Vol 28 (1) ◽  
pp. 60-66
Author(s):  
Tabassum Ghani ◽  
Subinoy Krishna Paul ◽  
Afrina Begum ◽  
Noorjahan ◽  
Mandira Sarkar ◽  
...  

Menopause is commonly associated with rapid bone loss and this bone loss manifests as a significant decrease in bone mineral density (BMD). Body weight or body mass index is the most important factor which influences BMD. Aim of this study was to evaluate the association between BMI and BMD in post menopausal women. Also to measure the correlation between age, duration of menopause, weight with BMD. This cross-sectional study was undertaken in the Department of Obstetrics and Gynaecology in Dhaka Medical College Hospital, Dhaka from January, 2012 to December, 2012. The study included women of 50 to 70 years who had menopause with three or more parity. Total 100 women were evaluated by history taking, physical examination and laboratory investigation (BMD).The results showed that there was significant positive correlation between BMI and BMD value of L1-4 and total femur (Pearson‘s coefficient was +0.285, P<0.01 and +.350, P<.001). There was also significant positive correlation between weight and T- score of L1-4 (r =+ .482, P<.01) and Total femur (r = +.513, P< .01). In addition, significant negative correlation was found between BMD with age and duration of menopause. It can be concluded that in postmenopausal women as the BMI decreases bone mineral density also decreases. So, adequate weight and BMI necessary for the prevention of osteoporosis. J Dhaka Medical College, Vol. 28, No.1, April, 2019, Page 60-66


Transfusion ◽  
2019 ◽  
Vol 59 (11) ◽  
pp. 3362-3370 ◽  
Author(s):  
Nareg H. Roubinian ◽  
Matt Westlake ◽  
Elizabeth M. St. Lezin ◽  
Gustaf Edgren ◽  
Don J. Brambilla ◽  
...  

2016 ◽  
Vol 27 (9) ◽  
pp. 2765-2775 ◽  
Author(s):  
A. B. Pedersen ◽  
D. Cronin Fenton ◽  
M. Nørgaard ◽  
N. R. Kristensen ◽  
B. Kuno Møller ◽  
...  

2020 ◽  
pp. 7-9
Author(s):  
Preethi. M ◽  
Ashraf A.Z ◽  
A.S. Anand ◽  
Yaranal P.J

Background: Red Blood Cell (RBC) histogram is a graphic representation of particle size distribution (cell frequencies verses size). RBC histogram with complete blood cell counts by automated analyser provides an idea about morphological changes of red blood cells in anaemias. Peripheral smear examination (PBS) helps in diagnosing different types of anaemias by visualizing abnormal shape and size, arrangement and immature red cells. This study was intended to analyze various types of anemia in pregnant women and to correlate RBC indices, RBC histogram with peripheral smear. Aims and Objectives: 1) To Correlate RBC indices, RBC histogram with peripheral smear in anemic pregnant women. 2) To categorize the type of anemia based on RBC indices, histogram and peripheral smear. Materials and Methods: Venous blood sample was run in SYSMEX XNL/350 six-part analyser. The haematological investigations of CBC, red blood cell indices (MCV, MCH, MCHC) and RBC histogram were obtained by analyser. Peripheral blood smear study was performed. Results: The present study included 55 cases among which in decreasing order of frequency, NNA (50.9%) was more common followed by MHA (40%), macrocytic anaemia (3.63%) and dimorphic anaemia (5.45%), as categorized by peripheral smear examination. Analysis by erythrocyte indices and histogram showed similar findings except in normocytic, microcytic and dimorphic which were 13.63%, 32.14% and 1.8% respectively. The correlation was done between the diagnosis made by the two methods which showed 76% concordance and discordance of 23.63%. Conclusion: Findings of the present study shows automated analyzer correlated well with PBS in cases of macrocytic and dimorphic anemia, compared to normocytic normochromic and microcytic hypochromic anaemia. As, RBC histogram with RBC indices and PBS are supplementary to each other, both should be used in conjunction for accurate diagnosis.


Author(s):  
Tazeen Khan ◽  
Zahid A. Khan ◽  
Sonia Kochhar ◽  
Baljinder Singh ◽  
Gurdev L. Goyal ◽  
...  

Background: Low hemoglobin concentration and unfeasible body mass index adversely affect the health of people, consequently increasing morbidity and mortality among them. Hemoglobin concentration among individuals is associated with their body mass index. The prevalence of iron deficiency anemia is higher among underweight and overweight/obese people compared to those with normal BMI. Thus, the present study aimed to determine the correlation between hemoglobin concentration and BMI of undergraduate medical students.Methods: A cross-sectional study was carried out among 210 undergraduate medical students. Body mass index was calculated and hemoglobin estimation was done by Sahli's hemoglobinometer. Correlation between hemoglobin concentration and body mass index of subjects was assessed by Pearson’s correlation coefficient.Results: Underweight students had lowest mean hemoglobin concentration and the mean hemoglobin concentrations increased significantly (p<0.001) with increase in the BMI of subjects. A highly significant positive correlation (r=0.307, p<0.001) between BMI and hemoglobin concentration was observed. Further, significant positive correlation was observed among males (r=0.268, p=0.013), students with normal BMI (r=0.283, p=0.003) and overweight students (r=0.415, p=0.035) only.Conclusions: Hemoglobin concentration and BMI show a positive correlation, however this correlation tends to become negative in obese individuals. As both low hemoglobin concentration and unfeasible body mass index have detrimental effects on the health, diligent screening and management of both is essential for better outcome.


PLoS ONE ◽  
2019 ◽  
Vol 14 (7) ◽  
pp. e0219549
Author(s):  
Isabela Borges Ferreira ◽  
Emanuelle do Nascimento Santos Lima ◽  
Nayara Cristina da Silva ◽  
Isaías Valente Prestes ◽  
Geórgia das Graças Pena

2019 ◽  
Vol 9 (3) ◽  
pp. 74-78
Author(s):  
Deepak Adhikari ◽  
Sudil Paudyal ◽  
Bigyan Paudel ◽  
Dipesh Paudel ◽  
Ishwor Acharya

 Background: Superior mesenteric artery syndrome is a rare but vital cause of upper gastrointestinal obstruction which occurs when the third portion of the duodenum is trapped between aorta and superior mesenteric artery. The sig­nificant decrease of the angle and distance between the superior mesenteric artery and aorta is the etiology of Superior mesenteric artery syndrome.The study aimed to identify the angulations and distance of superior mesenteric artery from aorta and their correlation with body mass index in patients re­ferred for contrast enhanced computed tomography of abdomen examination in Chitwan Medical College. Methods: The angle between the aorta and superior mesenteric artery was measured in arterial phase of the abdominal scan in the multiplanar recon­structed image in sagittal plane. The distance between the superior mesen­teric artery and aorta was measured in axial plane at the level of 3rd part of duodenum. Results: The aortomesenteric distance was obtained to be 13.30 ± 4.75 mm and the aortomesenteric angle was obtained to be 54.7±16.91 degree for a to­tal of 210 patients. There was a positive correlation between body mass index and aortomesenteric distance (p=0.086) and significant positive correlation between body mass index and aortomesenteric angle (p=0.122). Additionally, it showed there was significant positive correlation between aortomesenteric angle and aortomesenteric distance. Conclusions: The distance and angle between the superior mesenteric artery and the aorta correlates significantly with the body mass index which indicates that the decrease in body mass index can be used as a risk factor of superior mesenteric artery syndrome.


2018 ◽  
Vol 109 (5-6) ◽  
pp. 684-691 ◽  
Author(s):  
Kait Duncan ◽  
Anders C. Erickson ◽  
Grace M. Egeland ◽  
Hope Weiler ◽  
Laura T. Arbour

Sign in / Sign up

Export Citation Format

Share Document