scholarly journals Phenomenology of COPD: interpreting phenotypes with the ECLIPSE study

2016 ◽  
Vol 83 (1-2) ◽  
Author(s):  
Alberto Papi ◽  
Maria Sandra Magnoni ◽  
Carmelo Caio Muzzio ◽  
Gianmarco Benso ◽  
Andrea Rizzi
Keyword(s):  
Longitudinal Study ◽  
Disease Progression ◽  
Systemic Inflammation ◽  
Genetic Parameters ◽  
International Study ◽  
Medicinal Products ◽  
End Points ◽  
Clinical Prognosis ◽  
Predict Disease Progression

<p>The Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE) study was a large 3-year observational multicentre international study aimed at defining COPD phenotypes and identifying biomarkers and/or genetic parameters that help to predict disease progression. The study has contributed to a better understanding of COPD heterogeneity, with the characterization of clinically important subtypes/phenotypes of patients, such as the frequent exacerbators or patient with persistent systemic inflammation, who may have different prognosis or treatment requirements. Because of the big amount of information that is starting to be produced from metabolomic, proteomic and genomic approaches, one of the biggest challenges is the integration of data in a biological prospective such as clinical prognosis and response to medicinal products. In this article we highlight some of the progress in phenotyping the heterogeneity of the disease that have been made thanks to the analyses of this longitudinal study.</p>

scholarly journals Characterization of Retinal Disease Progression in a 1-Year Longitudinal Study of Eyes With Mild Nonproliferative Retinopathy in Diabetes Type 2

2015 ◽  
Vol 56 (9) ◽  
pp. 5698 ◽  
Author(s):  
Luisa Ribeiro ◽  
Francesco Bandello ◽  
Amparo Navea Tejerina ◽  
Stela Vujosevic ◽  
Monica Varano ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Disease Progression ◽  
Retinal Disease ◽  
Diabetes Type 2 ◽  
Diabetes Type

scholarly journals Characterization of Disease Progression in the Initial Stages of Retinopathy in Type 2 Diabetes: A 2-Year Longitudinal Study

2020 ◽  
Vol 61 (3) ◽  
pp. 20 ◽  
Author(s):  
Inês P. Marques ◽  
Dalila Alves ◽  
Torcato Santos ◽  
Luís Mendes ◽  
Conceição Lobo ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Longitudinal Study ◽  
Disease Progression

Comprehensive analysis of clinical prognosis and molecular immune characterization of tropomyosin 4 in pancreatic cancer

2021 ◽  
Author(s):  
Xue Zhou ◽  
Xiaowei Zhu ◽  
Junchao Yao ◽  
Xue Wang ◽  
Ning Wang
Keyword(s):  
Pancreatic Cancer ◽  
Comprehensive Analysis ◽  
Clinical Prognosis

M2044 Genetic Variations in GLI-1 and MDR-1 Do Not Predict Disease Progression in Patients with Ulcerative Colitis

2008 ◽  
Vol 134 (4) ◽  
pp. A-457
Author(s):  
Marc Ferrante ◽  
Tamara Coopmans ◽  
Isabelle Cleynen ◽  
Nathalie Vermeulen ◽  
Marie Joossens ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Disease Progression ◽  
Genetic Variations ◽  
Gli 1 ◽  
Mdr 1 ◽  
Predict Disease Progression

scholarly journals A longitudinal study of systemic inflammation and recovery of lean body mass among malnourished HIV-infected adults starting antiretroviral therapy in Tanzania and Zambia

2016 ◽  
Vol 70 (4) ◽  
pp. 499-504 ◽  
Author(s):  
G PrayGod ◽  
M Blevins ◽  
S Woodd ◽  
A M Rehman ◽  
K Jeremiah ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Antiretroviral Therapy ◽  
Lean Body Mass ◽  
Body Mass ◽  
Systemic Inflammation

Public networks for SME applications: implications for future SME networks

2004 ◽  
Vol 23 (3) ◽  
pp. 151-159
Author(s):  
Dong-Hee Shin
Keyword(s):  
New York ◽  
Longitudinal Study ◽  
Small Businesses ◽  
New York State ◽  
Network Development ◽  
York State ◽  
Public Network ◽  
Out Of The Loop ◽  
Public Networks

I discuss experiences in the development of four broadband public networking projects in New York State in order to see an implication for future small or medium-sized enterprise over such public networks. The projects were funded under a state program to diffuse broadband/advanced telecommunication technologies in economically depressed areas of the state. Through the broadband networks, I critically argue characterization of next generation public network (NGPN) in reference to small medium-sized enterprises (SMEs). I identify several facets of an NGPN drawing on a longitudinal study of the network development in four New York communities. As broadband public networks diffuse, small businesses being left out of the loop. The idea of SME application and service may itself be at risk. My approach to the socio-technical challenges involved in the design and development of broadband public networks is outlined.

scholarly journals Minimal Residual Disease in Melanoma:molecular characterization of in transit cutaneous metastases and Circulating Melanoma Cells recognizes an expression panel potentially related to disease progression

2020 ◽  
Vol 25 ◽  
pp. 100262
Author(s):  
Maria Cristina Rapanotti ◽  
Tara Mayte Suarez Viguria ◽  
Giulia Spallone ◽  
Alessandro Terrinoni ◽  
Piero Rossi ◽  
...  
Keyword(s):  
Disease Progression ◽  
Minimal Residual Disease ◽  
Residual Disease ◽  
Melanoma Cells ◽  
Cutaneous Metastases ◽  
In Transit ◽  
Minimal Residual
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