scholarly journals Investigation of the unfused cross cylinder test as an alternative method for the determination of spherical distance refraction end points

2020 ◽  
Vol 79 (1) ◽  
Author(s):  
Nkalebetja T. Makgaba ◽  
Solani D. Mathebula
Keyword(s):  
Adult Population ◽  
Test Results ◽  
End Points ◽  
Room Illumination ◽  
End Point ◽  
Cylinder Test ◽  
Significant Difference ◽  
Young Adult Population ◽  
The Mean

Background: The duochrome test is commonly used to refine the final sphere in refraction at different stages of a subjective refraction. The unfused cross cylinder test is mainly used to determine the near reading addition with a combination of astigmatic lenses.Aim: To investigate if the unfused cross cylinder test can be adapted for distance in finding the spherical end point for distance prescription.Setting: The study was conducted at an Optometry Clinic, University of Limpopo, South Africa.Methods: Fifty-one non-presbyopic subjects aged between 18 and 25 years were examined. The duochrome and unfused cross cylinder examinations were performed monocularly under normal (bright) and dim room illumination.Results: There was no significant difference in the spherical end point determined with either the duochrome or unfused cross cylinder tests (p ≥ 0.05). The mean spherical end points as determined with the duochrome test were −0.09 ± 0.39 diopre sphere (DS) (range: −0.20 to 0.12 dioptres [D]) in bright room illumination and −0.05 ± 0.38 DS (range: −0.16 D to 0.05 D) in dim illumination. The mean spherical end points for the unfused cross cylinder tests were −0.29 ± 0.39 DS (range: −0.18 D to 0.40 D) and −0.32 ± 0.43 DS (range: –0.44 D to –0.19 D) in room dim illuminations, respectively.Conclusion: The unfused cross cylinder test results as performed in this study may provide an accurate measurement of the spherical end point in a young adult population. We recommend the unfused cross cylinder test to be used in normal (bright) room illumination as an alternative to the duochrome test in the determination of distance refractive error.

scholarly journals Anthropogenetic variability in the groups of homo- and heterosexually oriented individuals

Genetika ◽  
2015 ◽  
Vol 47 (2) ◽  
pp. 765-776
Author(s):  
Suzana Cvjeticanin
Keyword(s):  
Genetic Variability ◽  
Population Genetic ◽  
Control Group ◽  
Population Genetic Study ◽  
Test Results ◽  
Mean Values ◽  
Significant Difference ◽  
The Mean ◽  
Distribution Type

This population-genetic study compares morphophysiological and genetic variability in a group of homosexually oriented individuals from Serbia (N=96) with control group of heterosexual individuals (N=96) using a test of determination of homozygously recessive characteristics in humans (HRC-test). Results of our study revealed a statistically significant difference in the mean values of genetic homozygosity (control group 5.0+0.2 ; homosexuals 3.4 +0.1 HRCs, out of 20 observed characteristics) the differences in the distribution type, as well as in the variances of presence of specific combinations of such traits. These results suggest a complex polygenic difference between two observed systems. There is no difference in the degree of genetic homozygosity between the genders in each tested group of individuals. However, both homosexually oriented females and males have significantly lower mean values of HRCs compared to female and male heterosexuals.

Determination of Resistance to Abrasive Wear. X. Investigation of the Durability of a Bonded Abrasive Wheel on the Du Pont Machine

1949 ◽  
Vol 22 (1) ◽  
pp. 264-268 ◽  
Author(s):  
R. G. Newton ◽  
J. R. Scott
Keyword(s):  
Abrasive Wear ◽  
Test Results ◽  
Volume Loss ◽  
Abrasive Wheel ◽  
Abrasive Particles ◽  
Significant Difference ◽  
Statistical Planning ◽  
The Mean ◽  
Test Result

Abstract The results reported here entirely confirm those of Lambourn, who found that marked deterioration occurred with all the types of abrasive wheel which he used. In the present investigation on a bonded wheel, it was concluded that the wheel was appreciably less abrasive after each period of. 50 hours' wear, while Lambourn concluded that one side of a wheel can be used for a period of two months when subjected to 40 hours of wear per week. Lambourn also concluded that the deterioration is caused by smoothing or disintegration of the abrasive particles and not by clogging with rubber dust, and points out that variation in abrasive wear can be compensated by daily tests on samples of a standard compound. He also states that a grain coarser than 24 should not be used, since the abrasion is too rapid. Since the standard emery papers vary among themselves, and the bonded abrasive wheel deteriorates when it is used, it is evident that attention should be paid to the statistical planning of these tests, so that these factors can be reduced or eliminated. The coefficient of variation of a test result, i.e., the mean of three 10-minute runs, each on duplicate specimens, (six individual readings) as normally measured, seems to be independent of the type of abrasive employed (emery papers or bonded disc) and the uncertainty of the result is about ±5 per cent when measured on the basis of volume loss per hour and about ±3.5 per cent when determined as the volume loss/H.P.-hr. Test results will therefore be required to differ by about 7 and about 5 per cent, respectively, for a significant difference to be demonstrated.

scholarly journals Sex and side determination of human hip bone by metric parameters of its posterior border

2013 ◽  
Vol 02 (01) ◽  
pp. 016-021
Author(s):  
Sarita R Margam ◽  
Megha A Doshi ◽  
Surekha D Jadhav ◽  
Raosaheb J Patil ◽  
Manoj P Ambali
Keyword(s):  
Sex Determination ◽  
Ischial Tuberosity ◽  
Test Results ◽  
Posterior Border ◽  
Bone Material ◽  
Significant Difference ◽  
The Mean ◽  
Two Parameters ◽  
Superior Border

Abstract Background: Identification of sex from skeletal remains is of medico-legal and anthropological importance for forensic experts, anthropologists and anatomists. Hip bone is considered as an ideal bone for sex determination as it provides the highest accuracy levels for sex determination. Aims: To determine the sex and side of the human hip bones by using different metric parameters of posterior border of hip bone. Material and methods: In present study, 200 (100 males and 100 females) dried adult human hip bones of known sex were collected. Two parameters were studied and statistically analysed by paired and unpaired 't' test. Results: In males, distance from the posterior superior iliac spine to the superior border of ischial tuberosity was the discriminant criteria to sex the hip bones while in females, it was distance between the posterior inferior iliac spine (PITS) to ischial tuberosity (IT). Statistically significant difference between the mean related to side were seen in both the variables. Conclusion: These two parameters can be used for sexual dimorphism as well as side determination of human hip bones or its fragments.

Detection of Circulating Tissue Factor and Factor VII in a Normal Population

1996 ◽  
Vol 75 (05) ◽  
pp. 772-777 ◽  
Author(s):  
Sybille Albrecht ◽  
Matthias Kotzsch ◽  
Gabriele Siegert ◽  
Thomas Luther ◽  
Heinz Großmann ◽  
...  
Keyword(s):  
Tissue Factor ◽  
Normal Population ◽  
Mean Value ◽  
Factor Vii ◽  
Significant Difference ◽  
Age Dependent ◽  
The Mean ◽  
Highly Correlated ◽  
And Gender

SummaryThe plasma tissue factor (TF) concentration was correlated to factor VII concentration (FVIIag) and factor VII activity (FVIIc) in 498 healthy volunteers ranging in age from 17 to 64 years. Immunoassays using monoclonal antibodies (mAbs) were developed for the determination of TF and FVIIag in plasma. The mAbs and the test systems were characterized. The mean value of the TF concentration was 172 ± 135 pg/ml. TF showed no age- and gender-related differences. For the total population, FVIIc, determined by a clotting test, was 110 ± 15% and the factor VIlag was 0.77 ± 0.19 μg/ml. FVII activity was significantly increased with age, whereas the concentration demonstrated no correlation to age in this population. FVII concentration is highly correlated with the activity as measured by clotting assay using rabbit thromboplastin. The ratio between FVIIc and FVIIag was not age-dependent, but demonstrated a significant difference between men and women. Between TF and FVII we could not detect a correlation.

scholarly journals Verbal Fluency Performance in Normal Adult Population in Iran: Norms and Effects of Age, Education and Gender

2021 ◽  
Author(s):  
Saeedeh Shirdel ◽  
◽  
Setareh Esmaeeli ◽  
Kaveh Alavi ◽  
Pezhman Ghaemmaghami ◽  
...  
Keyword(s):  
Clinical Assessment ◽  
Verbal Fluency ◽  
Standardized Test ◽  
Mother Tongue ◽  
Adult Population ◽  
Semantic Fluency ◽  
Semantic Categories ◽  
Persian Language ◽  
Significant Difference ◽  
The Mean

Objective: Verbal fluency is a cognitive function that can be easily assessed in bedside and provide useful data for clinical assessment of a variety of cognitive functions. We decided to provide a standardized test for the assessment of verbal fluency in Persian language, including both phonemic and semantic fluency subtests. Method: First, three letters (P, D, and Sh) and three categories (animals, fruits, and objects of kitchen) were selected based on a pilot study and a panel of specialists. Then, we selected 500 Persian speaking participants (47.8% male) that were 18 to 65 years old via convenient sampling from general population. Participants were stratified according to age, gender, and education. They performed the verbal fluency test. Results: The mean number of generated words in letter fluency and semantic fluency (±SD) were 8.3±4.1 and 18.0±5.5, respectively. Age, educational level, and mother tongue were associated with letter fluency. Semantic fluency was associated with age, gender, education level, and mother tongue. Conclusion: For a more reliable clinical assessment, we suggest to use all of the three letters and three semantic categories for each subject, calculate the mean of the produced words and compare them with the suggested cut-points provided for each subcategory. Age was negatively correlated with the number of generated words in letter fluency (r=-0.33; p<0.001) and semantic fluency tasks (r=-0.26; p<0.001). In letter fluency task, there was not a statistically significant difference between males and females according to the number of generated words (P=0.057). However, in semantic fluency, female participants generated more words (p=0.005). Mother tongue (Farsi) showed a significant effect both on letter fluency (t=5.55, p<0.001) and semantic fluency (t=9.41, p<0.001). Level of education had a significant association with both letter fluency (F=117.23, p<0.001) and semantic fluency (F=64.48, p<0.001).

Colorimetric Method for Rapid Determination of Serum Arginase

1967 ◽  
Vol 13 (10) ◽  
pp. 900-908 ◽  
Author(s):  
Brigitta Mellerup
Keyword(s):  
Rapid Determination ◽  
Colorimetric Method ◽  
Normal Range ◽  
Clinical Routine ◽  
Mean Values ◽  
Enzymatic Formation ◽  
Significant Difference ◽  
The Mean ◽  
Normal Men

Abstract A method for the determination of serum arginase is given which combines the enzymatic formation of urea with the sensitive method of Coulombe (1) for measuring this substance. This procedure allows more accurate determinations in the normal range than do previous methods described and is convenient for clinical routine. Significant difference is found between the mean values of normal men and women, 3.9 units/L. for the former and 2.9 units/L. for the latter.

scholarly journals Zero order and area under curve spectrophotometric methods for determination of Levocetirizine in pharmaceutical formulation

2015 ◽  
Vol 1 (6) ◽  
pp. 270
Author(s):  
Audumbar Digambar Mali ◽  
Ritesh Bathe ◽  
Manojkumar Patil ◽  
Ashpak Tamboli
Keyword(s):  
Area Under The Curve ◽  
Zero Order ◽  
Pharmaceutical Dosage Forms ◽  
Mean Values ◽  
Spectrophotometric Methods ◽  
Ich Guidelines ◽  
Significant Difference ◽  
Curve Method ◽  
The Mean

Simple, fast and reliable spectrophotometric methods were developed for determination of Levocetirizine in bulk and pharmaceutical dosage forms. The solutions of standard and the sample were prepared in methanol. The quantitative determination of the drug was carried out using the zero order derivative values measured at 230 nm and the area under the curve method values measured at 227-234 nm (n=2). Calibration graphs constructed at their wavelengths of determination were linear in the concentration range of Levocetirizine using 5-25?g/ml (r=0.998 and r=0.999) for zero order and area under the curve spectrophotometric method. All the proposed methods have been extensively validated as per ICH guidelines. There was no significant difference between the performance of the proposed methods regarding the mean values and standard deviations. Developed spectrophotometric methods in this study are simple, accurate, precise and sensitive to assay of Levocetirizine in tablets.

European Network on the Determination of Site End Points for Radiologically Contaminated Land

2007 ◽  
Author(s):  
Peter Booth ◽  
Chris Lennon
Keyword(s):  
Best Practice ◽  
Good Practice ◽  
State Agency ◽  
European Network ◽  
End Points ◽  
Contaminated Land ◽  
End Point ◽  
Land Site ◽  
High Level

Nexia Solutions are currently running a small European network entitled “European Network on the Determination of Site End Points for Radiologically Contaminated Land (ENDSEP)”. Other network members include NRG (Netherlands), UKAEA (UK), CEA (France), SOGIN (Italy), Wismut (Germany), Saxon State Agency of Environment and Geology (Germany). The network is focused on the technical and socio-economical issues associated with the determination of end points for sites potentially, or actually, impacted by radiological contamination. Such issues will cover: • Those associated with the run up to establishing a site end point; • Those associated with verifying that the end points have been met; and • Those associated with post closure. The network’s current high level objectives can be summarized as follows: • Share experience and best practice in the key issues running up to determining site end points; • Gain a better understanding of the potential effects of recent and forthcoming EU legislation; • Assess consistency between approaches; • Highlight potential gaps within the remit of site end point determination and management; and • Consider the formulation of research projects with a view to sharing time and expense. The programme of work revolves around the following key tasks: • Share information, experience and existing good practice. • Look to determine sustainable approaches to contaminated land site end point management. • Through site visits, gain first hand experience of determining an appropriate end point strategy, and identifying and resolving end point issues. • Highlight the key data gaps and consider the development of programmes to either close out these gaps or to build confidence in the approaches taken. • Production of position papers on each technical area highlighting how different countries approach/resolve a specific problem.

Effect of Administration Method on Near Point of Convergence Scores in a Healthy, Active, Young Adult Population

2018 ◽  
Vol 23 (4) ◽  
pp. 156-161
Author(s):  
Jacqueline Phillips ◽  
Kelly Cheever ◽  
Jamie McKeon ◽  
Ryan Tierney
Keyword(s):  
Young Adults ◽  
Young Adult ◽  
Assessment Tool ◽  
Adult Population ◽  
Significant Difference ◽  
Young Adult Population ◽  
Administration Method ◽  
Administration Methods

Near point of convergence (NPC) is an emerging concussion assessment tool and researchers have reported NPC scores using different administration methods which may influence assessment interpretation. The purpose of this study is to investigate the effect of different administrative methods on NPC scores in healthy, active young adults. NPC was measured using two different accommodative rulers and a fingertip, with three different placements. No significant difference in NPC score was observed between rulers. Significant differences were observed between ruler placements. Furthermore, fingertip use was significantly different compared to all ruler placements.

scholarly journals Orexitropic Signaling Proteins in Obese Children

2007 ◽  
Vol 7 ◽  
pp. 1263-1271 ◽  
Author(s):  
Ljiljana Saranac ◽  
Bojko Bjelakovic ◽  
Hristina Stamenkovic ◽  
Borislav Kamenov
Keyword(s):  
Body Mass ◽  
Central Obesity ◽  
Energy Homeostasis ◽  
Leptin Resistance ◽  
Signaling Proteins ◽  
Obese Children ◽  
Significant Difference ◽  
The Mean ◽  
Very High

Adipose tissue is not only the main organ for energy storage, but it also has endocrine properties, producing “adipokines” responsible for energy homeostasis, insulin sensitivity, and inflammation. Leptin, produced by adipocytes, is the key hormone in appetite regulation and suppression of orexigenic, hypothalamic neuropeptide Y (NPY). We wanted to establish and compare levels of leptin and NPY in different obesity types in childhood, and to investigate their correlations with auxological parameters. Twenty-one obese children (seven girls and 14 boys), divided into two groups, were compared with 14 controls. The mean age of the study group was 10.81 ± 3.69 years and the mean puberty stage was 2.21. The mean body mass index (BMI) was 32.80 kg/m2(range 23.30– 47.02) and the mean overweight 30.73 kg (range 8.00–74.00). The mean leptin level was higher in boys and in the group with central obesity, but was not significant. Leptin/NPY ratio and leptin/BMI ratio was also higher in the central obesity group and there was a more significant difference compared with controls. We found significant correlation of the leptin level with body mass (BM), body mass excess (BME), and BMI (p < 0.05). The mean leptin level in obese children was very high (36.39 ng/ml). Leptin and NPY levels showed inverse values in two different obesity types. Results are suggestive for leptin resistance rather than leptin deficiency in our group of obese children. Orexitropic signaling proteins correlated significantly with auxological parameters. Determination of the leptin and NPY concentrations provided evidence that obesity represents disease with neuroendocrine dysfunction and high leptin/NPY ratio, which could be a useful marker for central obesity.

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