scholarly journals Effect of water deficits on the growth and secondary metabolites of Salvia dolomitica Codd. and Salvia namaensis Schinz

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Shaheed Roos ◽  
Felix Nchu
Keyword(s):  
Medicinal Plants ◽  
Secondary Metabolites ◽  
Water Deficit ◽  
Water Deficits ◽  
Bioactive Natural Products ◽  
Fungal Activity ◽  
University Of Technology ◽  
Cape Peninsula ◽  
Number Of Stems ◽  
Anti Fungal

Background: Salvia dolomitica Codd. and Salvia namaensis Schinz. are indigenous to southern Africa and are used as medicinal plants in folk medicine.Aim: This study aimed to assess the effects of different levels of water deficit treatments on the growth, concentration of secondary metabolites, and anti-Fusarium oxysporum activity of S. dolomitica and S. namaensis.Setting: Experiments were carried out on the Bellville campus of the Cape Peninsula University of Technology, Cape Town.Methods: Four weeks old seedlings of the two species were subjected to 3-, 6-, 9- and 12-day water deficit regimes. Secondary metabolites such as polyphenols, alkaloids, and flavanols were assessed using spectroscopic methods. The anti-fungal activities of crude extracts obtained from plants were evaluated in a micro-dilution bioassay.Results: In all treatments, the plant height, crown width, number of stems and leaves, and fresh and dry weights reduced with increased water deficits. Acetone extracts from all treatments showed anti-fungal activity. However, extracts from the treatment with moderate water deficit (6-day watering interval) recorded significantly (P 0.01) better inhibition of F. oxysporum at the 18 h post incubation than the commercial fungicide, Mancozeb.Conclusion: This research has revealed that mild to moderate water deficit level favours the accumulation of alkaloids in S. dolomitica. Meanwhile, mild to severe water deficit significantly lowered flavanol content in S. namaensis. There was a correlation between the increase in total alkaloid contents and the enhanced anti-fungal activity of extracts of S. dolomitica. The present findings pave the way for optimised cultivation of medicinal plants and development of bioactive natural products.

Basotho Medicinal Plants Second Edition - Meriana ya dimela tsa Basotho Kgatiso ya Bobedi

2020 ◽  
Author(s):  
Rodney Moffett
Keyword(s):  
Medicinal Plants ◽  
Medicinal Plant ◽  
Indigenous Knowledge ◽  
Comprehensive List ◽  
Vernacular Names ◽  
Plant Use ◽  
Vice Chancellor ◽  
University Of Technology ◽  
Cape Peninsula ◽  
Plant Uses

As a Mosotho I believe this publication assists in documenting the deep indigenous knowledge of our forefathers and helps preserve the proud tradition of the Basotho Nation. Dr Chris Nhlapo Vice-Chancellor, Cape Peninsula University of Technology This publication is an important contribution to the documentation of medicinal plant use by the Basotho. It contains a comprehensive list of known medicinal plants, their up-to-date scientific names, their vernacular names, as well as their uses. This book will appeal to experts, as well as to readers who are unfamiliar with traditional medicinal plant uses. Professor Ntsamaeeng Moteetee Department of Botany and Plant Technology, University of Johannesburg

scholarly journals Efficacy of anti-bacterial and anti-fungal action on four medicinal plants extract the A.arabica, T.chebula, A.indica, and V.vinifera against Streptococcus mutans and Candida albicans -An in-vitro study

2019 ◽  
Vol 10 (4) ◽  
pp. 3121-3126
Author(s):  
Sunayana Manipal ◽  
Lubna Fathima ◽  
Sajid T Hussain ◽  
Venkat R
Keyword(s):  
Candida Albicans ◽  
Medicinal Plants ◽  
Medicinal Plant ◽  
Plant Extract ◽  
The Other ◽  
Dilution Method ◽  
Fungal Activity ◽  
Anti Fungal ◽  
Streptococcus Mutants ◽  
Plants Extract

The aim of the study was to test the anti-bacterial, and anti-fungal activity of four medical plants extract the A.arabica, T.chebula, A.indica, and V.vinifera against the streptococcus mutants and Candida albicans organisms. The extracts obtained from the medicinal plant of A.arabica, T.chebula, A.indica, and V.vinifera was procured and powdered. The minimum inhibitory concentration of the obtained extracts was determined by using the tube dilution method, and the bacterial strains of Streptococcus mutants and Candida albicans were cultured into the extract obtained at a concentration of 1mg/ml, 500µg/ml, 250µg/ml, and 100µg/ml respectively. The extracts obtained from A.arabica and T.chebula had a better anti-bacterial property when compared to the other two medicinal plants and the extracts obtained from A.indica and V.vinifera had a better anti-fungal property when compared to the other two medicinal plants. These plants extracts showed the anti-bacterial property in previous studies to add on to the review of literature in our study it proved that A.indica and V.vinifera had a better anti-fungal activity when compared to another two medicinal plant extract. The clinical significance of the medicinal plant extract can be effectively used as an anti-bacterial and anti-fungal agent as it was compared with the gold standard values of Streptomycin and Amphotericin B.

scholarly journals Identification and Bioactivities of Secondary Metabolites Derived from Endophytic Fungi Isolated from Ethnomedicinal Plants of Tujia in Hubei Province: A Review

2021 ◽  
Author(s):  
Ke Ye ◽  
Hong-Lian Ai ◽  
Ji-Kai Liu
Keyword(s):  
Medicinal Plants ◽  
Secondary Metabolites ◽  
Endophytic Fungi ◽  
Aromatic Compounds ◽  
Heterocyclic Compounds ◽  
New Drugs ◽  
National Minority ◽  
Natural Plant ◽  
Aliphatic Compounds ◽  
Bioactive Natural Products

AbstractTujia is a national minority, inhabiting in the mountainous Wuling area in China. Since 1978, Tujia medicine has been studied, summarized and developed, leading to numerous achievements by Chinese researchers, such as the publishing of approximately 30 monographs of Tujia medicine. These publications are focused on summarizing and improving the theory of Tujia medicine and developing clinical therapies from this system of medicine. The shortage of natural medicinal plants used in Tujia medicine has created the need to discover new resources to replace them and protect endangered natural plant species. Endophytic fungi are one of the conservation options, are considered a source of new bioactive natural products, and are a renewable and inexhaustible source of new drugs and agrochemicals. This review summarizes 260 compounds from endophytic fungi that have been previously isolated from the medicinal plants of Tujia. These compounds include steroids, terpenoids, meroterpenoids, polyketides, alkaloids, peptides, aliphatic compounds, aromatic compounds, and heterocyclic compounds. Graphic Abstract

In vitro anti-fungal activity of a plant-based ear gel and its essential oils

Planta Medica ◽  
2006 ◽  
Vol 72 (11) ◽  
Author(s):  
JK Ketzis ◽  
N Nolard ◽  
NS Ryder
Keyword(s):  
Essential Oils ◽  
Fungal Activity ◽  
Anti Fungal

scholarly journals Cylindromicin from Arctic-Derived Fungus Tolypocladium sp. SCSIO 40433

Molecules ◽  
2021 ◽  
Vol 26 (4) ◽  
pp. 1080
Author(s):  
Imran Khan ◽  
Jing Peng ◽  
Zhuangjie Fang ◽  
Wei Liu ◽  
Wenjun Zhang ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Nuclear Overhauser Effect ◽  
Inhibition Activity ◽  
Tyrosinase Inhibition ◽  
Bioactive Natural Products ◽  
Chemical Structures ◽  
Overhauser Effect ◽  
Spectroscopic Analyses ◽  
Potential Resource ◽  
Nuclear Overhauser

The fungus strain SCSIO 40433 was isolated from an Arctic-derived glacier sediment sample and characterized as Tolypocladium cylindrosporum. A new compound, cylindromicin (1), and seven known secondary metabolites (2–8) were isolated from this strain. The chemical structures of these compounds were elucidated by comprehensive spectroscopic analyses. Cylindromicin (1) featured a 3,4-dihydro-2H-pyran skeleton. The absolute configuration of compound 1 was assigned via interpretation of key Nuclear Overhauser Effect Spectroscopy (NOESY) correlations and Electronic Circular Dichroism (ECD) calculation. Cylindromicin (1) exhibited significant tyrosinase inhibition activity. This study highlights Polar fungi as a potential resource for new bioactive natural products.

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