Study of the antinociceptive effect of neem leaf extract and its interaction with morphine in mice

2005 ◽  
Vol 37 (1) ◽  
pp. 37 ◽  
Author(s):  
JagatD Bhatt ◽  
JP Patel ◽  
KG Hemavathi
AGRICA ◽  
2019 ◽  
Vol 1 (2) ◽  
pp. 32-37
Author(s):  
Yustina M.S.W Puu ◽  
Hildegardis Nalti Nansi

Callosobruchus Chinensis is a pest that damages mung bean seeds in storage and causes damage to both the quality and quantity of seeds. This study aims to determine the effectiveness of neem leaf extracts in suppressing the development of the Callosobruchus Chinensis pest as one of the postharvest pests in the commodity green beans. This research conducted at the Laboratory of the Faculty of Agriculture, University of Flores, by using a Completely Randomized Design (CRD) with five treatments and three replications. The concentration of neem leaf extract treatment is 0 ml / l, 25 ml / l, 30 ml / l, 35 ml / l, and 40 ml / l. The results showed that the concentration of neem leaf extract 40 ml / l caused mortality of C. Chinensis imago as contact poison by 99% and nerve poison by 47%. While the effectiveness of the limb leaf extract on spawning activity was 86%.


Author(s):  
Ifeanacho Ezeteonu Abireh ◽  
Onyinye Mary Ozioko ◽  
Ignatius Ikemefuna Ozor ◽  
Elizabeth Finbarrs- Bello ◽  
Uche Sebastine Ozioko ◽  
...  

Aim: This study investigated the curative effect of the aqueous leaf extract of Azadirachta indica on Ibuprofen-induced nephrotoxicity in Wistar rat Study Design: This is an experimental research Place of Research: Department of Anatomy, College of Medicine, Enugu State University of Science and Technology. Methodology: Twenty-four male Wistar rats were divided into 6 groups, with 4 rats in each group. Group 1 was control and received oral normal saline 0.5 ml daily. Group 2-6 had induction of nephrotoxicity using oral Ibuprofen 400 mg/Kg daily for 5 days. Group 3-5 were subsequently treated with gavage Azadirachta indica leaf extract 200 mg/Kg, 400 mg/Kg and 800 mg/Kg, respectively, for 5 days. And Group 6 was treated with oral Vitamin E 1000 iu/kg for 5 days. Results: Ibuprofen induced nephrotoxicity as evidenced by elevation of serum creatinine level in group 2 (1.99 ± 0.83), when compared to 0.48 ± 0.07 obtained in group 1 (control), and Bowman’s capsule enlargement with glomerular degeneration observed in group 2. The serum creatinine levels progressively approached the level of that of the control in groups treated with Azadirachta indica leaf extract, groups 3 (1.69 ± 0.52), 4 (0.69 ± 0.10) and 5 (0.49 ± 0.10). Also, the histoarchitecture progressively normalized to that of control with each increase in dose of the extract. Conclusion: Azadirachta indica (neem) leaf extract administration led to the resolution of Ibuprofen-induced kidney injury in this study. Thus, it can serve as a treatment option for kidney injury resulting from ingestion of Ibuprofen, after the identification of the molecule responsible for this effect.


2021 ◽  
Vol 36 (1) ◽  
pp. 9-15
Author(s):  
I.N Gana ◽  
V.U Ohageria ◽  
U.G Akpan ◽  
I.J Ani

The use of chemicals for the synthesis of photocatalyts poses threat to the environment. In this study, an active photocatalyst, Dalbejiya Dongoyaro (Azadirachta indica)-based zinc oxide (ZnO) was biosynthesized from zinc acetate dihydrate using sol gel and precipitation methods. The synthesized samples were characterized using Fourier Transfer InfraRed (FTIR), X-Ray Diffractometry (XRD), Brunauer Emmet Teller (BET), Energy Dispersive X-ray Spectroscopy (EDS) and Scanning Electron Microscopy (SEM) characterization techniques. The XRD and SEM analysis of the green synthesized and non-green synthesized ZnO demonstrated the formation of hexagonal wurtzite crystalline structure and agglomerated morphology. EDX analysis demonstrated the existence of Zn and O as the major constituents of the as-synthesized nanoparticles with traces of carbon which could be attributed to the carbon tape of the sample holder. The BET analysis displayed that the surface area of the ZnO nanoparticles increased from 23.75 to 97.08 cm3/g after the green synthesis. Based on the surface area values, it can be derived that neem leaf extract enhanced the surface area of the green synthesized sample. Green synthesis is a promising route for the synthesis of photocatalyst nanoparticle which is environmentally friendly and sustainable method. Keywords: Zinc oxide, Neem leaf extract, Photocatalyt, Degradation, Bio-synthesis


2018 ◽  
Vol 16 (3) ◽  
pp. 343-350 ◽  
Author(s):  
Rabeya Akter Sarmin ◽  
Shamim Ahmed Kamal Uddin Khan ◽  
Kanij Fatema ◽  
Sabiha Sultana

The study was carried out to minimize the postharvest loses and extend shelf life of mango fruitby maintaining physico-chemical properties. The variety selected for the study was “Amrapali”. Freshly harvested mango was treated with different concentrations (20% and 40%) of neem leaf and banana pulp extract alone or in combination. Untreated mango was considered as control. All treated and untreated mango was kept into paper cartons at room condition. The treated fruits showed significant differences in case of total soluble solids content, titratable acidity, vitamin C, disease incidence, disease severity and shelf life in comparison to control fruits. Among the treatments, T2 (neem leaf extract at 20%) and T5 (neem leaf extract 40% + banana pulp extract 40%) treatments showed longer shelf life (9.92 and 10.25 days, respectively), slower changes in color (score 2.77 and 2.93, respectively) and firmness (score 2.67 and 2.77, respectively); less disease severity (score 2.93 and 3.57, respectively), disease incidence (46.67% and 60.00%) and lower loss in weight (38.04% and 35.17%, respectively) at 9 DAT (Days after treatment). On the other hand, total soluble solid was highest in T3 (neem leaf extract 40%) treated fruitswith18.73% more Brix at 13 DAT in comparison to control and other treatments. The effectiveness of the treatment T5 (neem leaf extract 40% + banana pulp extract 40%) was meaningful which could be recommended for maintenance of postharvest quality of mango stored in ambient conditions. J. Bangladesh Agril. Univ. 16(3): 343–350, December 2018


2007 ◽  
Vol 14 (4) ◽  
pp. 369-374 ◽  
Author(s):  
A U Mbah ◽  
I J Udeinya ◽  
E N Shu ◽  
C P Chijioke ◽  
T Nubila ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document