Validation of hearing handicap inventory for the elderly questionnaire among elderly subjects in Sagamu, Nigeria

The purpose of this study was to explore the contributions of audiologic and nonaudiologic factors, including medical, social, economic, and psychological, towards understanding hearing handicap in black elderly. One hundred hearing-impaired black elderly subjects from Harlem Hospital were given audiologic evaluations, including speech recognition tests under varied conditions. Audiologic factors were significantly related to hearing handicap, measured by the Hearing Handicap Scale (HHS) and the Hearing Handicap Inventory for the Elderly (HHIE), with stronger correlations for speech recognition measured at 50 dB HL in a sound field than at 40 dB SL under earphones. Once hearing loss was taken into consideration, nonaudiologic factors (measured on the Multidimensional Functional Assessment Questionnaire), particularly the dependability dimension of social support and the lethargy and paranoid dimensions of mental health, emerged as contributing predictor variables for HHS and HHIE scores. These findings suggest that a multidimensional approach is key to understanding and remediating hearing handicap in black elderly.

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Extra Virgin Olive Oil Prevents the Age-Related Shifts of the Distribution of HDL Subclasses and Improves Their Functionality

Nutrients ◽

10.3390/nu13072235 ◽

2021 ◽

Vol 13 (7) ◽

pp. 2235

Author(s):

Alyann Otrante ◽

Amal Trigui ◽

Roua Walha ◽

Hicham Berrougui ◽

Tamas Fulop ◽

...

Keyword(s):

Olive Oil ◽

Virgin Olive Oil ◽

Density Lipoprotein ◽

Extra Virgin Olive Oil ◽

The Elderly ◽

High Density ◽

Lipoprotein Cholesterol ◽

Elderly Subjects ◽

Age Related ◽

Young Subjects

High-density lipoproteins (HDL) maintain cholesterol homeostasis through the role they play in regulating reverse cholesterol transport (RCT), a process by which excess cholesterol is transported back to the liver for elimination. However, RCT can be altered in the presence of cardiovascular risk factors, such as aging, which contributes to the increase in the incidence of cardiovascular diseases (CVD). The present study was aimed at investigating the effect of extra virgin olive oil (EVOO) intake on the cholesterol efflux capacity (CEC) of HDL, and to elucidate on the mechanisms by which EVOO intake improves the anti-atherogenic activity of HDL. A total of 84 healthy women and men were enrolled and were distributed, according to age, into two groups: 27 young (31.81 ± 6.79 years) and 57 elderly (70.72 ± 5.6 years) subjects. The subjects in both groups were given 25 mL/d of extra virgin olive oil (EVOO) for 12 weeks. CEC was measured using J774 macrophages radiolabeled with tritiated cholesterol ((3H) cholesterol). HDL subclass distributions were analyzed using the Quantimetrix Lipoprint® system. The HDL from the elderly subjects exhibited a lower level of CEC, at 11.12% (p < 0.0001), than the HDL from the young subjects. The CEC of the elderly subjects returned to normal levels following 12 weeks of EVOO intake. An analysis of the distribution of HDL subclasses showed that HDL from the elderly subjects were composed of lower levels of large HDL (L-HDL) (p < 0.03) and higher levels of small HDL (S-HDL) (p < 0.002) compared to HDL from the young subjects. A multiple linear regression analysis revealed a positive correlation between CEC and L-HDL levels (r = 0.35 and p < 0.001) as well as an inverse correlation between CEC and S-HDL levels (r = −0.27 and p < 0.01). This correlation remained significant even when several variables, including age, sex, and BMI as well as low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and glucose levels (β = 0.28, p < 0.002, and β = 0.24, p = 0.01) were accounted for. Consuming EVOO for 12 weeks modulated the age-related difference in the distribution of HDL subclasses by reducing the level of S-HDL and increasing the level of intermediate-HDL/large-HDL (I-HDL/L-HDL) in the elderly subjects. The age-related alteration of the CEC of HDL was due, in part, to an alteration in the distribution of HDL subclasses. A diet enriched in EVOO improved the functionality of HDL through an increase in I-HDL/L-HDL and a decrease in S-HDL.

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POS1288 TUBERCULOUS SPONDYLODISCITIS IN ELDERLY: EPIDEMIOLOGY, CLINICAL, FEATURES, TREATMENT AND OUTCOMES

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2021-eular.4129 ◽

2021 ◽

Vol 80 (Suppl 1) ◽

pp. 926.1-926

Author(s):

M. Mrabet ◽

S. Boussaid ◽

S. Jemmali ◽

H. Sahli ◽

H. Ajlani ◽

...

Keyword(s):

Clinical Features ◽

The Elderly ◽

Lumbar Pain ◽

Elderly Subjects ◽

Normocytic Anemia ◽

Imaging Features ◽

X Rays ◽

Significant Difference ◽

Young Subjects ◽

Tuberculous Spondylodiscitis

Background:Tuberculosis is still endemic all over the world. The incidence of tuberculous spondylodiscitis (TS) is steadily increasing. Clinical features and outcomes of this affection are various and depending on various parameters, including age.Objectives:Our objective was to explore the differences in presentation and the results of further investigations and the prognosis of TS between young and elderly subjects.Methods:We conduct a retrospective and descriptive study in a single rheumatology department. Data were collected from files of patients hospitalized in the past 20 years (2000-2020) who have been diagnosed with TS. We carried out a comparative study concerning the clinical biological, imaging features and outcomes between young subjects and subjects aged over 65 years.Results:Fifty-two cases of TS were collected (37F/15M). The mean age of the population was 55.21 years ± 17.79 [19-91]. Thirty-three patients (69.2%) were classified as young versus 16 elderly patients (30.8%), with female predominance in both groups (69.4% and 75% respectively, p = 0.57). Young subjects was more frequently vaccinated (88.9%) by Bacillus Calmette–Guérin (BCG) (p < 0.001). A delayed diagnosis was noted in both groups (p = 0.24). Lumbar spine involvement was the most common (57.7%). In the two age ranges, the onset of the disease was progressive (p = 0.22), characterized by segmental spine stiffness (p = 0.57) and lumbar pain with general signs (p = 0.27), such as: impaired general condition, fever, night sweats and weight loss. Biological inflammatory syndrome and normochrome normocytic anemia were encountered in both cases (p = 0.08 and p = 0.2, respectively). Standard X-rays and Computed tomography were more performed in young subjects (94.4% and 69.4%, respectively; p < 0.001), unlike magnetic resonance imaging which was more common in elderly subjects but with no statistically significant difference (p = 0.22). Disc pinch, erosion of vertebral plateaus and vertebral collapse were the major signs (82.7%, 65.4% and 67.3%, respectively). Clinical, biological and imaging arguments contributed to positive diagnosis in both groups (p = 0.24). Common medical treatment was anti-tuberculosis: Isoniazid (H), Rifampicin (R), Pyrazinamide (Z), Ethambutol (E) and physical treatment such as immobilization witch was more common in the eldery (56.3%, p = 0.16). The evolution of the disease was characterized by a clear improvement of young subjects during the second week of treatment (p < 0.001). A more frequent clinical improvement in older subjects was during the fourth week but with no statistically significant difference (p = 0.13). The occurrence of immediate complications was more frequent in the elderly (p = 0.23) with a predominance for drug complications (56.3%) such as: hepatic cytolysis (12.5%), hyperuricemia (18.8%) and major intolerance to anti-tuberculosis (18.8%).Conclusion:TS is a frequent condition that needs to be treated rapidly. the clinical presentation of TS in the elderly is less noisy which leads to more frequent complications and mortality.Disclosure of Interests:None declared

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Audiometric Correlates of the Hearing Handicap Inventory for the Elderly

Journal of Speech and Hearing Disorders ◽

10.1044/jshd.4804.379 ◽

1983 ◽

Vol 48 (4) ◽

pp. 379-384 ◽

Cited By ~ 77

Author(s):

Barbara E. Weinstein ◽

Ira M. Ventry

Keyword(s):

The Elderly ◽

Hearing Handicap

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Decreased Neutrophil Cyclic AMP Response to Isoprenaline Stimulation in the Elderly

Clinical Science ◽

10.1042/cs0650155 ◽

1983 ◽

Vol 65 (2) ◽

pp. 155-157 ◽

Cited By ~ 13

Author(s):

T. G. Cotter ◽

K. O'Malley

Keyword(s):

Monoclonal Antibodies ◽

Cyclic Amp ◽

The Elderly ◽

Population Heterogeneity ◽

Elderly Subjects ◽

Age Related ◽

Significant Difference ◽

Young Subjects ◽

Drug Free

1. Neutrophils from drug-free elderly subjects produced approximately 50% less cyclic AMP in response to isoprenaline than did neutrophils from young subjects. A significant difference in basal cyclic AMP levels was also evident (elderly 2.8 ± 0.37; young 4.9 ± 0.36 pmol of cAMP/107 cells; P < 0.05). 2. With a range of anti-neutrophil monoclonal antibodies no evidence of age-related neutrophil population heterogeneity was found. 3. These findings indicate that the age-related decline in β-adrenoceptor responsiveness is not due to changes in the neutrophil population. 4. The present results support the hypothesis that there is a generalized decline in β-adrenoceptor-mediated responsiveness in the elderly.

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Reliability and Stability of Various Hearing-Aid Outcome Measures in a Group of Elderly Hearing-Aid Wearers

Journal of Speech Language and Hearing Research ◽

10.1044/jshr.3905.923 ◽

1996 ◽

Vol 39 (5) ◽

pp. 923-935 ◽

Cited By ~ 61

Author(s):

Larry E. Humes ◽

Dan Halling ◽

Maureen Coughlin

Keyword(s):

Outcome Measures ◽

Hearing Aids ◽

Repeated Measures ◽

Nonsense Syllable ◽

Hearing Aid ◽

Objective Measure ◽

The Elderly ◽

Elderly Persons ◽

Hearing Aid Use ◽

Hearing Handicap

Twenty elderly persons with hearing impairment were fit with binaural in-the-ear hearing aids and followed for a 6-month period post-fit. Several hearing-aid outcome measures were obtained at 0, 7, 15, 30, 60, 90, and 180 days post-fit. Outcome measures included (a) objective measures of benefit obtained with nonsense-syllable materials in quiet (CUNY Nonsense Syllable Test, NST) and sentences in multitalker babble (Hearing in Noise Test, HINT); (b) two subjective measures of benefit, one derived from pre-fit/post-fit comparisons on a general scale of hearing handicap (Hearing Handicap Inventory for the Elderly, HHIE) and the other based on a subjective scale of post-fit hearing-aid benefit (Hearing Aid Performance Inventory, HAPI); (c) a questionnaire on hearing-aid satisfaction; (d) an objective measure of hearing-aid use; and (e) a subjective measure of hearing-aid use. Reliability and stability of each measure were examined through repeated-measures analyses of variance, a series of test-retest correlations, and, where possible, scatterplots of the scores against their corresponding 95% critical differences. Many of the measures were found to be both reliable and stable indicators of hearing-aid outcome.

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Cold-induced Increases in Erythrocyte Count, Plasma Cholesterol and Plasma Fibrinogen of Elderly People without a Comparable Rise in Protein C or Factor X

Clinical Science ◽

10.1042/cs0860043 ◽

1994 ◽

Vol 86 (1) ◽

pp. 43-48 ◽

Cited By ~ 110

Author(s):

Penelope J. Neild ◽

Denise Syndercombe-Court ◽

W. R. Keatinge ◽

G. C. Donaldson ◽

M. Mattock ◽

...

Keyword(s):

Elderly People ◽

Plasma Volume ◽

Arterial Thrombosis ◽

Protein C ◽

Plasma Cholesterol ◽

The Elderly ◽

Erythrocyte Count ◽

Elderly Subjects ◽

Factor X ◽

Young Subjects

1. Six elderly (66-71 years) and six young (20-23 years) subjects (half of each group women) were cooled for 2 h in moving air at 18°C to investigate possible causes of increased mortality from arterial thrombosis among elderly people in cold weather. Compared with thermoneutral control experiments, skin temperature (trunk) fell from 35.5 to 29.5°C, with little change in core temperature. 2. Erythrocyte count rose in the cold from 4.29 to 4.69 × 1012/l, without a change in mean corpuscular volume, indicating a 14% or 438 ml decline in plasma volume; increased excretion of water, Na+ and K+ accounted for loss of only 179 ml of extracellular water. 3. Plasma cholesterol and fibrinogen concentrations rose in the elderly subjects from 4.9 mmol/l and 2.97 g/l (control) to 5.45 mmol/l and 3.39 g/l in the cold, and in the young subjects from 3.33 mmol/l and 1.84 g/l (control) to 3.77 mmol/l and 2.07 g/l in the cold. Increases were significant for the elderly subjects, the young subjects and the group as a whole, except for cholesterol in the young subjects, and all were close to those expected from the fall in plasma volume. 4. Plasma levels of Protein C and factor X did not increase significantly in the cold in the elderly subjects, young subjects, or the group as a whole. 5. The results suggest that loss of plasma fluid in the cold concentrates major risk factors for arterial thrombosis, while small molecules, including protective Protein C, redistribute to interstitial fluid.

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Implicações do uso do Aparelho de Amplificação Sonora Individual na qualidade de vida de idosos

CoDAS ◽

10.1590/2317-1782/20172016241 ◽

2017 ◽

Vol 29 (5) ◽

Cited By ~ 2

Author(s):

Camila Zorzetto Carniel ◽

Juliana Cristina Ferreira de Sousa ◽

Carla Dias da Silva ◽

Carla Aparecida de Urzedo Fortunato-Queiroz ◽

Miguel Ângelo Hyppolito ◽

...

Keyword(s):

Quality Of Life ◽

World Health Organization ◽

The Elderly ◽

World Health ◽

World Health Organization Quality ◽

Hearing Handicap ◽

Organization Quality ◽

Health Organization ◽

Post Hoc

RESUMO Objetivo Avaliar, por meio de questionários padronizados, a qualidade de vida de idosos com deficiência auditiva diagnosticada que utilizam ou não a prótese auditiva (AASI) e de idosos sem queixa auditiva. Método Trata-se de um estudo transversal, com amostra não probabilística, distribuída em três grupos divididos da seguinte forma: 30 idosos com perda auditiva diagnosticada e com indicação para uso do aparelho de amplificação sonora individual (AASI), mas que ainda não faziam uso da prótese; 30 idosos com deficiência auditiva que usavam o AASI; e 30 idosos sem queixa auditiva. Os participantes completaram um questionário que investigava dados sociodemográficos e familiares, o Hearing Handicap Inventory for the Elderly Screening Version (HHIE-S) e o World Health Organization Quality of Life - versão breve (WHOQOL-Breve). Além das análises descritivas dos dados, foram realizados testes para comparação dos três grupos, aplicando-se a análise de variância (ANOVA) e o teste post hoc de Bonferroni. Resultados Os três grupos se diferenciaram significativamente em todos os domínios de qualidade de vida. O grupo de idosos com perda auditiva diagnosticada e com indicação para uso do AASI apresentou menores escores que o grupo de idosos com deficiência auditiva que usavam o AASI e que o grupo de referência. O grupo com AASI apresentou os melhores resultados de qualidade de vida. Conclusão A perda auditiva afeta a qualidade de vida do idoso. O uso efetivo da prótese auditiva é benéfico a esta população, melhorando suas condições de vida e saúde.

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Human Nonmercaptalbumin Is a New Biomarker of Motor Function

Journal of Clinical Medicine ◽

10.3390/jcm10112464 ◽

2021 ◽

Vol 10 (11) ◽

pp. 2464

Author(s):

Sadayuki Ito ◽

Hiroaki Nakashima ◽

Kei Ando ◽

Kazuyoshi Kobayashi ◽

Masaaki Machino ◽

...

Keyword(s):

Oxidative Stress ◽

Logistic Regression ◽

Regression Analysis ◽

Grip Strength ◽

Motor Function ◽

Walking Speed ◽

The Elderly ◽

Elderly Subjects ◽

Locomotive Syndrome ◽

Reduced Mobility

The ratio of human nonmercaptalbumin (HNA) and reduced albumin (HMA) may be a new marker for oxidative stress. Locomotive syndrome (LS) is reduced mobility due to impairment of locomotive organs. We investigated whether the HNA/HMA ratio could be a new biomarker of LS. This study included 306 subjects (mean age 64.24 ± 10.4 years) who underwent LS tests, grip strength, walking speed, and tests for HNA and HMA. Oxidative stress was measured by the ratio of HMA (f(HMA) = (HMA/(HMA + HNA) × 100)), and the subjects were divided into normal (N group; f[HMA] ≥ 70%) and low (L group; f[HMA] < 70%) groups. There were 124 non-elderly (<65 years) and 182 elderly subjects (≥65 years). There were no significant differences in LS, grip strength, and walking speed between the L and N groups in the non-elderly subjects. However, significant differences were found in the elderly subjects. In logistic regression analysis, there was an association between f(HMA) and the LS severity at older ages. LS in the elderly is associated with a decline in HMA and, thus, an increase in oxidative stress. Thus, f(HMA) is a new biomarker of LS.

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The influence of dynamic visual environments on postural sway in the elderly

Journal of Vestibular Research ◽

10.3233/ves-1999-9307 ◽

1999 ◽

Vol 9 (3) ◽

pp. 197-205

Author(s):

L.L. Borger ◽

S.L. Whitney ◽

M.S. Redfern ◽

J.M. Furman

Keyword(s):

Visual Information ◽

Postural Sway ◽

Center Of Pressure ◽

Age Groups ◽

The Elderly ◽

Visual Scene ◽

Elderly Subjects ◽

Mean Velocity ◽

Healthy Elderly ◽

Young Subjects

Postural sway during stance has been found to be sensitive to moving visual scenes in young adults, children, and those with vestibular disease. The effect of visual environments on balance in elderly individuals is relatively unknown. The purpose of this study was to compare postural sway responses of healthy elderly to those of young subjects when both groups were exposed to a moving visual scene. Peak to peak, root mean squared, and mean velocity of the center of pressure were analyzed under conditions combining four moving scene amplitudes ( 2 . 5 ∘ , 5 ∘ , 7 . 5 ∘ , 10 ∘ ) and two frequencies of scene movement (0.1 Hz, 0.25 Hz). Each visual condition was tested with a fixed floor and sway referenced platform. Results showed that elderly subjects swayed more than younger subjects when experiencing a moving visual scene under all conditions. The elderly were affected more than the young by sway referencing the platform. The differences between the two age groups were greater at increased amplitudes of scene movement. These results suggest that elderly are more influenced by dynamic visual information for balance than the young, particularly when cues from the ankles are altered.

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