Correlation of burn injury and family history of burns among patients hospitalized at a public hospital in Nairobi, Kenya: A case–control study

Abstract Background Previous studies have indicated inconsistent relationships of diabetes with thyroid cancer risk, yet little is known in China. In this study, we aimed to investigate the associations between diabetes, diabetes duration and the risk of thyroid cancer in Chinese population. Methods A 1:1 matched case-control study was performed between 2015 and 2017 in Zhejiang Province including 2,937 thyroid cancer cases and 2,937 healthy controls. Odds ratios (ORs) with 95 % confidence intervals (CIs) for thyroid cancer were estimated in logistic regression models. Specific effects stratified by age, as well as sex, body mass index (BMI) and family history of diabetes were also examined. Results Overall, neither diabetes (OR = 0.75, 95 % CI: 0.21–2.73) nor diabetes duration (OR = 0.14, 95 % CI: 0.02–1.22 for diabetes duration ≦ 5 years; OR = 2.10, 95 % CI: 0.32–13.94 for diabetes duration > 5 years) was significantly associated with thyroid cancer. In stratified analyses, significant lower risk of thyroid cancer was observed among subjects with diabetes and shorter diabetes duration ( ≦ 5 years), but limited to those who were aged more than 40 years, female, overweight/obese and had positive family history of diabetes. Conclusions Diabetes and shorter diabetes duration were significantly associated with decreased risk of thyroid cancer in individuals characterized by older age, female sex, higher BMI and positive family history of diabetes.

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Family history of hypertension increases risk of preeclampsia in pregnant women: a case-control study

Zinc supplementation improves heme biosynthesis in rats exposed to lead ◽

10.18051/univmed.2016.v35.181-191 ◽

2016 ◽

Vol 35 (3) ◽

pp. 181 ◽

Cited By ~ 1

Author(s):

Mulualem Endeshaw ◽

Fantu Abebe ◽

Melkamu Bedimo ◽

Anemaw Asrat ◽

Abebaw Gebeyehu ◽

...

Keyword(s):

Family History ◽

Pregnant Women ◽

Case Control Study ◽

Multiple Logistic Regression Analysis ◽

Multiple Pregnancy ◽

Case Control ◽

Outcome Variable ◽

History Of ◽

Family History Of Hypertension ◽

Control Study

Background Preeclampsia is one of the leading causes of maternal and fetal morbidity and mortalities worldwide. Despite extensive research, the underlying cause of preeclampsia remains poorly understood. This study aimed to offer compelling evidence on the important risk factors of preeclampsia in Amhara region, Ethiopia. Methods A case control study was conducted in public health facilities of Bahir Dar city from September 2014 to January 2015. A total of 453 (151 cases and 302 controls) pregnant women were enrolled in this study. Hemoglobin level and urinary tract infection (UTI) status were collected from clinical notes. Oral examination was performed by a dentist for detection of periodontal diseases. Univariate and multiple logistic regression analysis was conducted to determine the relationship of all the independent variables with the outcome variable. A p-value <0.05 was declared statistically significant. Result Advanced maternal age (AOR=4.79;95% CI 1.031-22.18), family history of hypertension (AOR=11.16;95% CI 5.41-41.43), history of diabetes mellitus (AOR=6.17;95% CI 2.11-20.33), UTI in the current pregnancy (AOR=6.58;95% CI 2.93-14.73), failure to comply with iron and folic acid supplement during pregnancy (AOR=8.32;95% CI 3.35-20.62), lack of exercise (AOR=3.33;95% CI 1.35-8.17), multiple pregnancy (AOR=4.05;95% CI 1.57-12.27), anemia (AOR=4.19;95% CI 1.27-13.92), and periodontal disease or gingivitis (AOR =3.51;95% CI 1.14-10.83) were associated with preeclampsia. Conclusion Family history of hypertension was the most dominant risk factor for preeclampsia in pregnant women. Encouraging pregnant women to have health seeking behavior during pregnancy would provide a chance to diagnose preeclampsia as early as possible.

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Relation of Family History of Cancer and Environmental Factors to the Risk of Colorectal Cancer: A Case-control Study

Japanese Journal of Clinical Oncology ◽

10.1093/oxfordjournals.jjco.a039777 ◽

1995 ◽

Cited By ~ 1

Keyword(s):

Colorectal Cancer ◽

Family History ◽

Environmental Factors ◽

Case Control Study ◽

Case Control ◽

Family History Of Cancer ◽

History Of ◽

Control Study ◽

History Of Cancer

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Maternal interview reports of family history of birth defects: Evaluation from a population-based case-control study of orofacial clefts

American Journal of Medical Genetics ◽

10.1002/(sici)1096-8628(19971112)72:4<422::aid-ajmg10>3.0.co;2-t ◽

1997 ◽

Vol 72 (4) ◽

pp. 422-429 ◽

Cited By ~ 3

Author(s):

Paul A. Romitti ◽

Trudy L. Burns ◽

Jeffrey C. Murray

Keyword(s):

Family History ◽

Birth Defects ◽

Case Control Study ◽

Population Based ◽

Case Control ◽

Orofacial Clefts ◽

History Of ◽

Control Study

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346. Factors Associated with Hypertension in Young Adults with Perinatally-Acquired HIV Infection: a Case–Control Study

Open Forum Infectious Diseases ◽

10.1093/ofid/ofz360.419 ◽

2019 ◽

Vol 6 (Supplement_2) ◽

pp. S184-S184

Author(s):

Patrick O’Neil ◽

Patrick Ryscavage ◽

Kristen A Stafford

Keyword(s):

Risk Factors ◽

Young Adults ◽

Family History ◽

Case Control Study ◽

Case Control ◽

Systemic Hypertension ◽

Early Management ◽

Factors Associated ◽

History Of ◽

Control Study

Abstract Background The incidence of systemic hypertension (HTN) among perinatally-HIV-infected (PHIV) patients appears to increase as they enter adulthood. Among non-perinatally HIV-infected adults both traditional and HIV-associated risk factors have been found to contribute to HTN. Whether these same factors contribute to HTN in PHIV is unknown. The purpose of this study was to determine the socio-demographic, clinical, virologic, and immunologic factors associated with HTN among a cohort of PHIV adolescents and young adults, aged ≥18 years. Methods We conducted a case–control study among a population of 160 PHIV adults with and without HTN who were receiving care at the University of Maryland and aged 18–35 years as of December 31, 2017. Covariates assessed included traditional risk factors such as age, family history of HTN, and smoking, as well as HIV- and antiretroviral-associated covariates. Results We identified 49 HTN cases (30.6%) and 111 (69.4%) controls. There were no significant differences in the odds of most traditional (age, gender, race, family history of HTN, tobacco, alcohol, and/or other drug use) or HIV-associated (CD4 nadir <100 cells/mm3, individual ART exposure, ART interruption) risk factors among PHIV adults with HTN compared with those with no diagnosis of HTN. Cases had lower odds of a history of treatment with lopinavir/ritonavir (LPV/r). Cases had 3.7 (95% CI 1.11, 12.56) times the odds of a prior diagnosis of chronic kidney disease (CKD) compared with controls after controlling for CD4 nadir and ARV treatment history. Conclusion The results of this study suggest that most traditional and HIV-related risk factors do not appear to increase the odds of having HTN in this PHIV cohort. However, HTN among PHIV may be driven in part by CKD, and a focus on the prevention and early management of CKD in this group may be necessary to prevent the development of HTN. Additionally, there may be as yet unidentified risk factors for HTN among PHIV which require further exploration. Given the large and growing population of PHIV entering adulthood worldwide, it is imperative to explore risk factors for and effects of HTN in large, diverse PHIV populations. Disclosures All authors: No reported disclosures.

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