Self-esteem, metacognition, and coping strategies in cancer patients: A case–control study

Background: The prevalence of Cervical Cancer (CC) is disproportionately higher in developing countries. It is the second most frequent cancer type among Bangladeshi women and the primary cause of morbidity and mortality. However, no previous data reported the association of miR-218-2 gene polymorphisms in Bangladeshi cervical cancer patients. Aim: This case-control study was designed to find the link between the rs11134527 polymorphism in miR-218-2 and CC. Methods: A total of 488 subjects were recruited, comprising 256 cervical cancer patients and 232 healthy females. Genotyping was conducted with the tetra-primer ARMS-PCR technique to detect the association. Results: The results of genotype data showed that rs11134527 obeyed the Hardy-Weinberg equilibrium in both CC cases and controls (P >0.05). Overall, the polymorphism was found to be significantly associated with an increased risk of cervical cancer with AG genotype (AG vs. GG: OR = 2.26, 95% Cl = 1.40-3.66, P = 0.0008), AA genotype (AA vs. GG: OR = 3.64, 95% Cl = 2.17-6.10, P <0.0001), dominant model (AG+AA vs. GG: OR = 2.75, 95% Cl = 1.75-4.31, P <0.0001), recessive model (AA vs. GG+AG: OR = 2.08, 95% Cl = 1.41-3.08, P = 0.0002), and A allele (A vs. G: OR = 1.94, 95% Cl = 1.51-2.51, P <0.0001). All of these correlations remained statistically significant after performing Bonferroni correction (P <0.008). Conclusion: Our study suggests that the rs11134527 polymorphism in the miR-218-2 gene contributes to the susceptibility of CC in Bangladeshi women.

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Mindfulness-based Stress Reduction (MBSR) in cancer patients: prospective single-centre case-control study (MIND4ME study)

Annals of Oncology ◽

10.1093/annonc/mdw342.02 ◽

2016 ◽

Vol 27 ◽

pp. iv92

Author(s):

M. Maur ◽

A. Guida ◽

M.P. Ricchieri ◽

F. Caggia ◽

G. Pontoni ◽

...

Keyword(s):

Cancer Patients ◽

Stress Reduction ◽

Case Control Study ◽

Case Control ◽

Single Centre ◽

Mindfulness Based Stress Reduction ◽

Control Study

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Interaction between serotonin reuptake inhibitors, 5-HT3 antagonists, and NK1 antagonists in cancer patients receiving highly emetogenic chemotherapy: a case–control study

Supportive Care in Cancer ◽

10.1007/s00520-012-1503-y ◽

2012 ◽

Vol 20 (9) ◽

pp. 2235-2239 ◽

Cited By ~ 6

Author(s):

Olivier Mir ◽

Jean-Philippe Durand ◽

Pascaline Boudou-Rouquette ◽

Julie Giroux ◽

Romain Coriat ◽

...

Keyword(s):

Cancer Patients ◽

Serotonin Reuptake ◽

Case Control Study ◽

Case Control ◽

Emetogenic Chemotherapy ◽

Serotonin Reuptake Inhibitors ◽

Highly Emetogenic Chemotherapy ◽

Control Study

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Quantitative Assessment of Serum Magnesium Levels in Head and Neck Cancer: A Tertiary Hospital Based Case Control Study

Journal of Advances in Medicine and Medical Research ◽

10.9734/jammr/2021/v33i2031183 ◽

2021 ◽

pp. 249-257

Author(s):

Surender Kumar ◽

Neha Salaria ◽

Deepak Verma ◽

Uma Garg ◽

Monika Verma

Keyword(s):

Head And Neck Cancer ◽

Head And Neck ◽

Cancer Patients ◽

Neck Cancer ◽

Case Control Study ◽

Serum Magnesium ◽

Tertiary Care ◽

Case Control ◽

Control Group ◽

Control Study

Background- Head and neck squamous cell carcinomas(HNSCC) are one of the most widespread malignancies worldwide. Trace elements such as magnesium are essential at cellular level, and it has been suggested that magnesium plays a role in carcinogenesis. Methods- A hospital based case control study was conducted in a tertiary care medical college with an aim to determine the levels of serum magnesium in patients with head and neck cancer and to compare the levels of serum magnesium of head and neck cancer patients with healthy matched control group and derive significance if any. Results- HNSCC was mainly found in males of age group 46 to 55 years. The mean serum Mg value of head and neck cancer patients was 0.71± 0.18 mmol/l while that seen in controls was 0.85± 0.09 mmol/l which was significantly lower(p<0.001). Average serum magnesium levels in stages I, II, III and IV were 0.85, 0.849, 0.682 and 0.554 mmol/l respectively, and a statistically significant association was determined between the two. Conclusion- As the stage of cancer progressed, average magnesium levels decreased congruently, hence establishing that magnesium levels were undeniably correlated to onset as well as progression of HNC. These evidences could be utilized to identify role of magnesium asa potential prognostic biomarker to assess progression of disease or clinical response to various modes of therapy in head and neck cancer patients.

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