scholarly journals A clinicopathologic study of placentae of low birth weight and normal birth weight babies born at a tertiary care center in western India

2021 ◽  
Vol 14 (2) ◽  
pp. 166
Author(s):  
JasvinderKaur Bhatia ◽  
Manish Sharma ◽  
Ajay Malik
PEDIATRICS ◽  
1986 ◽  
Vol 77 (2) ◽  
pp. 158-166
Author(s):  
Nigel Paneth ◽  
Sylvan Wallenstein ◽  
John L. Kiely ◽  
Curtis P. Snook ◽  
Mervyn Susser

Preterm infants of normal birth weight (born before 37 completed weeks of gestation and weighing more than 2,250 g) experience a neonatal mortality risk almost four times higher than do term infants in the same weight range. In an analysis of the effect of hospital level of birth on neonatal mortality, such preterm normal weight infants were found to experience higher mortality if born outside of a Level 3 (tertiary care) center. For all singleton infants in this weight-gestation category born in New York City maternity services during a 3-year period (N = 23,257), the relative mortality risk for Level 1 births (compared with Level 3) was 1.72 (P < .01) and for Level 2 births 1.47 (P < .05). The excess mortality at Level 1 and Level 2 units was almost entirely due to a more than twofold higher death rate in black infants born in these units. Several potentially confounding socioeconomic, demographic, and biologic variables entered into a logistic regression model could not account for the higher mortality rates for black infants born in Level 1 and Level 2 units. Among black infants born at Level 1 units, deaths in preterm normal birth weight infants were less likely to occur in a receiving tertiary care center than were either deaths in low birth weight infants or deaths in term normal weight infants, suggesting that the need for special care of preterm normal birth weight infants is underestimated in some hospitals without newborn intensive care units.


2018 ◽  
Vol 89 (4) ◽  
pp. 224-232 ◽  
Author(s):  
Hala Tfayli ◽  
Lama Charafeddine ◽  
Hani Tamim ◽  
Joanne Saade ◽  
Rose T. Daher ◽  
...  

Background/Aims: Preterm newborns with a very low birth weight (VLBW) of < 1,500 g have an atypical form of hypothyroidism with a delayed rise in TSH, necessitating a second newborn screening specimen collection. The aims of this study were to survey the compliance with second newborn screening to detect delayed TSH rise in VLBW preterm infants at a tertiary care center, and to determine the rate of atypical hypothyroidism. Methods: Retrospective review of the records of 104 preterm VLBW infants. Late TSH rise was defined as an increase in TSH concentration after 14 days of age in the presence of a normal initial screen. Results: The compliance rate was 92% for the second screening. High rates of hypothyroidism (16.3%) and of late TSH rise (4.8%) were detected. Patients with hypothyroidism had a significantly lower birth weight (p = 0.01) and longer hospital stay (p = 0.004). Patients with late versus those with early TSH rise had a significantly lower mean birth weight (851 ± 302 vs. 1,191 ± 121 g, p = 0.004). Conclusion: The rates of early and late TSH rise in this VLBW population were higher than those in the literature and could be due to the use of povidone-iodine disinfectants. The yield of a second TSH screening in this study was high indicating the need for vigilance in screening VLBW preterm infants.


2021 ◽  
pp. 22-25
Author(s):  
Yogesh Thawal ◽  
Meenal M. Patvekar ◽  
Prashant Suryarao ◽  
Dipak Suresh Kolate ◽  
Shayari Jain ◽  
...  

Background: Teenage pregnancies are associated with high degree of maternal and neonatal complications. As many adolescents are neither physically nor psychologically ready for pregnancy or childbirth, this reproductive event makes them more vulnerable to complications resulting in devastating health sequences for them. Objectives: Our objective is to study feto-maternal outcomes in teenage pregnancy for betterment of society & for abetting economic burden on country. This observational Materials & Methods: study was done over 2 years at our tertiary care center - Dr DY Patil Medical College, Hospital and Research Institute, Pimpri, Pune. A total of 205 participants were included in the study after obtaining informed consent from the patients who satised the inclusion of age more than or equal to 18 years and lesser than 20 years. Operative interventions like D&E Results : , LSCS were increased in teenage pregnancies with emergency LSCS in 36.58% of the participants. First trimester & Antepartum complications were common in teenage pregnancies. Even Intrapartum & Post partum complications were contributed signicantly to feto-maternal morbidity & mortality . 54.04% had low birth weight and only 40.91% had normal birth weight. A total 64 NICU admissions were needed from 193 live births. Of these 12 expired in early neonatal period (<7 days) whereas 7 expired between 7 to 28 days. Among those who survived, almost 40 % had perinatal hypoxia. There were 96.98% live births whereas 3.01% IUD. Conclusion : Teenage pregnancy is a condition which gives rise to further complications and affects both the maternal as well as the neonatal health. Hence it is important that at every level of the society there is awareness regarding sexual education, use of contraceptives and the ill effects of teenage pregnancy.


2018 ◽  
Vol 5 (4) ◽  
pp. 1272
Author(s):  
Manish Rasania ◽  
Sunil Pathak ◽  
Prerna Dogra ◽  
Ayushi Jain ◽  
Neil Shah ◽  
...  

Background: Low birth weight (LBW) has been defined as a birth weight of <2.5 kilogram regardless of gestational age. In India, every 3rd born child is of LBW. LBW is associated with increased neonatal mortality and morbidity, compromised growth and cognitive development.Methods: This is a retrospective cohort study using previously collected data from January 2015 to December 2015.Results: Out of 1238 live births, 485 (39.17%) were LBW. 456(94.01%) were LBW weighing >1500 grams (LBW), 22(4.53%) were VLBW, and 07(1.44%) were ELBW. 361(74.43%) were LBW2 (birth weight ≥2000 - <2500 grams), 95(19.58%) were LBW1 (birth weight ≥1500 - <2000 grams). 289(59.58%) of LBW neonates were full term. SNCU admission is significantly higher in LBW neonates (25.8% vs 9.61%). Morbidities were higher in LBW neonates compared to normal birth weight neonates. Difference was more significant in incidence of sepsis (3.72% vs 0.83%), RDS (2.19% vs 0%), TTN (5.48% vs 2.36%), hypoglycemia (1.31% vs 0%), feed intolerance (1.09% vs 0%) and risk of major congenital malformation (1.97% vs 0.27%). Need for respiratory support was 4.82% in LBW vs 2.36% in normal birth weight neonates. Morbidities were significantly higher in VLBW and ELBW neonates. Immediate poor outcome was in 3.92% in LBW neonates, while it was 0.56% in normal weight neonates. Poor immediate outcome was 1.11% in LBW2, 2.10% in LBW1, 10% in VLBW1, 41.66% IN VLBW2, and 100% in ELBW.Conclusions: LBW neonates are at higher risk of morbidities and mortalities. The major determinant for mortality in LBW babies is the birth weight. The best option to prevent LBW is by improving maternal health. Improvement of perinatal and neonatal services   in government sector and public private partnership model of free neonatal care can help to achieve the INAP goal of NMR <10 by 2030. 


Author(s):  
Binit Singh ◽  
Rizwan Haider ◽  
Ved Prakash Gupta

Background: Premature infants have avascular or incompletely vascularized retina at birth and ROP evolves over 4-5 weeks after birth. The aim of this study is to know the prevalence of retinopathy of prematurity in preterm infants, with birth weight ? 1500 grams and/or gestational age ?32 weeks in a tertiary care center. Material and methods: The study was conducted in a tertiary care center of Bihar region India The sample size is 145 babies. All preterm infants admitted with a birth weight of ?1500 grams and/or ? 32 weeks of gestation and baby those at risk of ROP. Results: 145 babies have enrolled during the study period of which 124 babies fulfilled the inclusion criteria and completed this prospective study.15 babies could not complete the follow-up protocol and 6 babies died before full vascularization of the retina. 124 babies who fulfilled the inclusion criteria were screened and 33 babies were found to have ROP. The prevalence of ROP in this study is 26.6%. Conclusions: Among the preventable causes of blindness in children, ROP figures very high on the agenda. Low birth weight and gestational age were found to be the most important risk factors for the development of ROP. Keywords: Low birth weight, Prematurity in preterm infant, Retinopathy, Oxygen therapy


2018 ◽  
Vol 5 (2) ◽  
pp. 377 ◽  
Author(s):  
Ravikumar S. A. ◽  
Harikrishnan Elangovan ◽  
Elayaraja K. ◽  
Aravind Sunderavel K. K.

Background: Accurate data on morbidity and mortality pattern are useful for many reasons. The Perinatal and the neonatal period are so short but they are the most critical faces of human life1. It reflects the general health and the socio-biological features of the most vulnerable groups of the society, the mothers and the infants. The objectives of this study was to investigate the morbidity and mortality pattern of neonates admitted in Neonatal Intensive Care Unit (NICU) of tertiary care hospital.Methods: All the neonates admitted to NICU from July 2013 to June 2015, excluding the neonates referred and discharged against medical advice were retrospectively analysed for demographic profile, short term morbidity and outcome.Results: 3118 neonates were admitted in the study period. 57.5% were Males, 72.5% were inborn, 69% were term babies and 53.3% had normal birth weight. Important causes for morbidity were Perinatal asphyxia 490 (15.7%), Preterm/LBW 456 (14.6%), Neonatal jaundice 438 (14%) and then sepsis 402 (12.9%). The mortality rate was 10.4% with statistical significant difference between inborn and outborn babies (P<0.0001). The major causes of mortality are Respiratory syndrome 109 (33.6%), followed by birth asphyxia 82 (25.3%) and sepsis 82 (25.3%). The survival of term as well as normal birth weight babies was statistically significant over preterm (P<0.0001) and Low Birth Weight (LBW), Very Low Birth Weight (VLBW), Extreme Low Birth Weight (ELBW) neonates (P<0.0001> respectively.Conclusions: Birth asphyxia, prematurity, Jaundice and neonatal sepsis respiratory problems were major causes of both mortality and morbidity. There is need to strengthen services to address these problems more effectively. 


Cureus ◽  
2021 ◽  
Author(s):  
Mohammed Y Al-Hindi ◽  
Bashaer H Almahdi ◽  
Dinah A Alasmari ◽  
Raghad K Alwagdani ◽  
Wujud M Hunjur ◽  
...  

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