scholarly journals Morbidity and mortality profile of neonates in a tertiary care centre in Tamil Nadu: a study from South India

2018 ◽  
Vol 5 (2) ◽  
pp. 377 ◽  
Author(s):  
Ravikumar S. A. ◽  
Harikrishnan Elangovan ◽  
Elayaraja K. ◽  
Aravind Sunderavel K. K.
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Tamil Nadu ◽  
Tertiary Care ◽  
Birth Asphyxia ◽  
Morbidity And Mortality ◽  
Normal Birth Weight ◽  
Mortality Pattern ◽  
Normal Birth ◽  
Significant Difference

Background: Accurate data on morbidity and mortality pattern are useful for many reasons. The Perinatal and the neonatal period are so short but they are the most critical faces of human life1. It reflects the general health and the socio-biological features of the most vulnerable groups of the society, the mothers and the infants. The objectives of this study was to investigate the morbidity and mortality pattern of neonates admitted in Neonatal Intensive Care Unit (NICU) of tertiary care hospital.Methods: All the neonates admitted to NICU from July 2013 to June 2015, excluding the neonates referred and discharged against medical advice were retrospectively analysed for demographic profile, short term morbidity and outcome.Results: 3118 neonates were admitted in the study period. 57.5% were Males, 72.5% were inborn, 69% were term babies and 53.3% had normal birth weight. Important causes for morbidity were Perinatal asphyxia 490 (15.7%), Preterm/LBW 456 (14.6%), Neonatal jaundice 438 (14%) and then sepsis 402 (12.9%). The mortality rate was 10.4% with statistical significant difference between inborn and outborn babies (P<0.0001). The major causes of mortality are Respiratory syndrome 109 (33.6%), followed by birth asphyxia 82 (25.3%) and sepsis 82 (25.3%). The survival of term as well as normal birth weight babies was statistically significant over preterm (P<0.0001) and Low Birth Weight (LBW), Very Low Birth Weight (VLBW), Extreme Low Birth Weight (ELBW) neonates (P<0.0001> respectively.Conclusions: Birth asphyxia, prematurity, Jaundice and neonatal sepsis respiratory problems were major causes of both mortality and morbidity. There is need to strengthen services to address these problems more effectively. 

scholarly journals Comparing Growth and Development of Low and Normal Birth Weight Children at Age of 60 Months

2020 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Najmeh Maharlouei ◽  
Sogand Farhangian ◽  
Hadi Raeisi Shahraki ◽  
Abbas Rezaianzadeh ◽  
Kamran Bagheri Lankarani
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Growth And Development ◽  
Normal Birth Weight ◽  
Growth Indices ◽  
Normal Birth ◽  
Significant Difference ◽  
Low Birth Weight Children ◽  
Children's Development ◽  
Children’S Development

Background: Low birth weight (LBW < 2500 g) is one of the most serious problems in today’s world. It is also a predictor for mortality and stunting. Objectives: This study aimed to compare the growth and development at the age of 60 months between children born with low and normal birth weight in Shiraz, Iran. Methods: This study is part of the Fars birth cohort (FBC) study with the data of children who were born in 2011. We called mothers and asked them to bring their children to the FBC clinic for further evaluation. We also determined the level of development at the age of 60 months for each child by using the Ages and Stages questionnaire (ASQ) for the children. Results: Of the children, 304 (51.4%) were girls. Most of them had normal birth weight (93.2%), had exclusive breastfeeding for five to six months (79.9%), and did not have any chronic diseases (77.8%). Growth indices at the age of 60 months were significantly higher in children with normal birth weight than in their LBW peers (P < 0.001). However, we found no significant difference in children’s development at the age of 60 months between normal and low birth weight children. Conclusions: Although growth indices of children at the age of 60 months were higher in children with normal birth weight, we found no significant difference in children’s development at the age of 60 months between normal and low birth weight children.

OUTCOME OF LOW BIRTH WEIGHT NEONATES WITH RELATION TO EARLY ANEMIA.

2021 ◽  
pp. 1-3
Author(s):  
Anmol Kaur Sidhu ◽  
Preeti Malhotra
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Cross Sectional Study ◽  
Morbidity And Mortality ◽  
Normal Birth Weight ◽  
Sectional Study ◽  
Exclusion Criteria ◽  
Cross Sectional ◽  
Normal Birth ◽  
Elbw Neonates

Background: Weight of newborn is a universal predictor of health during childhood. Haematological prole varies with period of gestation in low birth weight neonates i.e., <2500 grams. They have different haematological prole as compared to normal birth weight neonates. Aim of this study is to relate early morbidity and mortality of low birth weight neonates and their haemoglobin at days 1, 4 and 7. Materials and methods: A prospective cross-sectional study was conducted from January 2019 to June 2020 on children weighing below 2500 grams admitted within 24 hours of birth in Department of Paediatrics, SGRDIMSR, Amritsar. A total of 110 neonates were enrolled in this study following the inclusion and exclusion criteria. Haemoglobin levels of these were measured on days 1, 4 and 7. The data obtained was compiled and analysed to reach valid conclusions in relation to outcome in form of morbidity and mortality of the subjects. Results: Among 110 neonates majority belong to category of birth weight between 1500-2500 grams (70%). Lowest mean haemoglobin levels were seen in ELBW (<1000 grams) neonates. Fall in haemoglobin from day 1 to 7 in all the neonates was seen and was statistically signicant. Anaemia was signicantly related to PNA and mortality. Lowest mean haemoglobin values were seen in neonates with PNA as a morbidity on day 7 (13.04±2.32). Neonates who died had even lower haemoglobin level on day 7 (12.17±2.03). Conclusion: It was concluded that ELBW neonates had higher risk of early anaemia as compared to LBW and VLBW neonates. Anaemia was also signicantly present in neonates who died and those who had PNA. Thus early anaemia is associated with PNA, ELBW and Mortality.

scholarly journals Morbidity and Mortality of Low Birth Weight Baby

1970 ◽  
Vol 21 (1) ◽  
pp. 35-39 ◽  
Author(s):  
MI Bari ◽  
MA Ullah ◽  
M Khatun
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Birth Asphyxia ◽  
Analytical Techniques ◽  
Neonatal Morbidity ◽  
Morbidity And Mortality ◽  
Chi Square ◽  
College Hospital ◽  
Normal Birth ◽  
A Prospective Study

This was a prospective study conducted in a cohort of live normal full term singleton newborns delivered in Rajshahi Medical College Hospital with the objective to explore their early neonatal health as well as the role of low birth weight on it. A total 770 live normal newborns were Included in this study. For data collection APGAR Score Estimating Checklist and one protested structured questionnaire were used. Simple descriptive as well as analytical techniques including Chi-square t test were done. The results of this study suggested that low weight (LBW) babies were more prone to develop early neonatal morbidity and mortality than normal birth weight (NBW) babies. LBW infants needed more resuscitation and responded less to resuscitative effort than the infants of NBW. Birth asphyxia was the commonest cause of early neonatal morbidity and mortality.    doi: 10.3329/taj.v21i1.3216 TAJ 2008; 21(1): 35-39

scholarly journals Morbidity profile and immediate outcome of low birth weight neonates in a rural tertiary care hospital of Gujarat, India

2018 ◽  
Vol 5 (4) ◽  
pp. 1272
Author(s):  
Manish Rasania ◽  
Sunil Pathak ◽  
Prerna Dogra ◽  
Ayushi Jain ◽  
Neil Shah ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Tertiary Care ◽  
Normal Weight ◽  
Health Improvement ◽  
Care Hospital ◽  
Normal Birth Weight ◽  
Mortality And Morbidity ◽  
Normal Birth ◽  
Partnership Model

Background: Low birth weight (LBW) has been defined as a birth weight of <2.5 kilogram regardless of gestational age. In India, every 3rd born child is of LBW. LBW is associated with increased neonatal mortality and morbidity, compromised growth and cognitive development.Methods: This is a retrospective cohort study using previously collected data from January 2015 to December 2015.Results: Out of 1238 live births, 485 (39.17%) were LBW. 456(94.01%) were LBW weighing >1500 grams (LBW), 22(4.53%) were VLBW, and 07(1.44%) were ELBW. 361(74.43%) were LBW2 (birth weight ≥2000 - <2500 grams), 95(19.58%) were LBW1 (birth weight ≥1500 - <2000 grams). 289(59.58%) of LBW neonates were full term. SNCU admission is significantly higher in LBW neonates (25.8% vs 9.61%). Morbidities were higher in LBW neonates compared to normal birth weight neonates. Difference was more significant in incidence of sepsis (3.72% vs 0.83%), RDS (2.19% vs 0%), TTN (5.48% vs 2.36%), hypoglycemia (1.31% vs 0%), feed intolerance (1.09% vs 0%) and risk of major congenital malformation (1.97% vs 0.27%). Need for respiratory support was 4.82% in LBW vs 2.36% in normal birth weight neonates. Morbidities were significantly higher in VLBW and ELBW neonates. Immediate poor outcome was in 3.92% in LBW neonates, while it was 0.56% in normal weight neonates. Poor immediate outcome was 1.11% in LBW2, 2.10% in LBW1, 10% in VLBW1, 41.66% IN VLBW2, and 100% in ELBW.Conclusions: LBW neonates are at higher risk of morbidities and mortalities. The major determinant for mortality in LBW babies is the birth weight. The best option to prevent LBW is by improving maternal health. Improvement of perinatal and neonatal services   in government sector and public private partnership model of free neonatal care can help to achieve the INAP goal of NMR <10 by 2030. 

scholarly journals Histological Study of Placental Changes in Low Birth Weight Neonates in a Tertiary Care Hospital

2020 ◽  
Author(s):  
Geethapriya Govindarajan ◽  
Shivashekar Ganapathy ◽  
Muthu Sudalaimuthu
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Tertiary Care ◽  
Research Centre ◽  
Care Hospital ◽  
Normal Birth Weight ◽  
Histological Changes ◽  
Major Health Problem ◽  
Maternal Risk ◽  
Normal Birth

Introduction: Low Birth Weight (LBW) in the newborn is a major health problem in our country and across the world. Identifying the pathological changes in placenta can help in understanding the pathogenesis of LBW babies. Aim: To compare histological changes in placenta of LBW baby and normal birth weight baby and to find out the maternal risk factors associated with LBW baby. Materials and Methods: A case-control study was done on a total of 140 samples which were collected in the study period of August 2017-August 2019 in SRM Medical College Hospital and Research Centre, Chennai, Tamil Nadu, India, with 70 placentas from LBW delivery and 70 placentas from normal birth weight delivery. Placentas from preterm delivery were excluded from this study. Histological changes in placenta were assessed in both the groups. Statistical analysis was done with Statistical Package for the Social Sciences (SPSS) version 17. Independent sample Student’s t-test and Chi-square test were used for comparison between two groups. Results: Histological changes like chorioamnionitis, syncitial knots, calcification, Perivillous Fibrin Deposition (PVFD), stromal fibrosis and basement membrane thickening were observed more frequently in placentas from LBW delivery. The commonest histological finding in present study was villous stromal fibrosis in 58 cases (82.9%) followed by excessive syncytial knots in 57 cases (81.4%). In this study, anaemia was the commonest maternal risk factor associated with LBW baby. Conclusion: The structure of placenta has strong relationship with the pregnancy outcome. There are few significant histological changes in placenta of LBW neonates. These changes have an impact in the development of the baby. Study about these changes provides a scope for prevention of certain morbidities in subsequent pregnancies.

scholarly journals Frequency, risk factors and materno-foetal outcomes among cases of Placenta previa at a tertiary care hospital: a two year study

2019 ◽  
Vol 8 (6) ◽  
pp. 2240
Author(s):  
Pamulaparthi Bindu Reddy ◽  
Gurram Swetha Reddy
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Tertiary Care Hospital ◽  
Placenta Previa ◽  
Tertiary Care ◽  
Previous History ◽  
Morbidity And Mortality ◽  
Care Hospital ◽  
Early Date

Background: Placenta previa refers to the presence of placental tissue that extends over the internal cervical os.  Placenta previa is linked to maternal hypovolemia, anaemia, and long hospital stay and with prematurity, low birth weight, low APGAR score in newborn. So it is very important to identify the condition at an early date to warn the condition thereby reducing the maternal and foetal morbidity and mortality. The present study was aimed to estimate the prevalence of PP, its associated predisposing risk factors and maternal morbidity, mortality and the perinatal outcome.Methods: A prospective observational study for two years was conducted at a tertiary care hospital. Pregnant mothers with >28 weeks of age with H/o ante partum haemorrhage were screened for placenta previa, confirmed by ultra sonography and included in the study. Clinical history, obstetric examination was done and followed up till the delivery. Maternal and foetal outcomes were recorded. Data analyzed by using SPSS version 20.Results: 1.4% incidence of PP was noted, mean age of group was 29.17±1.6 years. Age group of 21-30 years, multiparity Gravida 2-4, previous history of caesarean section and less number of ante natal checkups were significant risk factors and LSCS was most common outcome. Prematurity, low birth weight and APGAR <7 score for 1 minute was common foetal outcomes.Conclusions: Our study strongly suggests foetal surveillance programmes in cases of placenta previa. Measures should be made to bring awareness about PP, in urban slums and to increase medical checkups regularly. Making USG mandatory during every ANC and referral of cases of PP to tertiary care centres would definitely reduce the chances of morbidity and mortality.

Antioxidant Levels in Cord Blood of Term Low Birth Weight Neonates Requiring Delivery Room Resuscitation

2021 ◽  
pp. 097321792199140
Author(s):  
Rimjhim Sonowal ◽  
Anamika Jain ◽  
V. Bhargava ◽  
H.D. Khanna ◽  
Ashok Kumar
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Vitamin A ◽  
Cord Blood ◽  
Serum Levels ◽  
Study Groups ◽  
Delivery Room ◽  
Normal Birth Weight ◽  
Normal Birth ◽  
Major Congenital Malformations

Objective: The objective of this study was to evaluate the serum levels of various antioxidants, namely, vitamin A and E, superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPx) in the cord blood of term low birth weight (LBW) neonates who required delivery room resuscitation (DRR). Materials and Methods: This case control study included 37 term LBW neonates who needed DRR as cases and 44 term neonates as controls (15 term LBW and 29 term normal birth weight) who did not require resuscitation at birth. Neonates suffering from major congenital malformations, infection, or hemolytic disease were excluded. Standard methods were used to measure the levels of vitamin A, vitamin E, SOD, catalase, and GPx levels in the cord blood. Results: Vitamin A and E levels were significantly low in cases compared to term LBW controls as well as term normal birth weight controls. Levels of SOD, GPx, and catalase were comparable in different study groups. Conclusion: Our study shows that term LBW neonates requiring DRR had significantly low levels of vitamin A and E in their cord blood. This might compromise their ability to tolerate oxidative stress during DRR.

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