Inhibitory Roles of Nigella sativa seed extracts on in vitro glycation and aggregation

2021 ◽  
Vol 17 (6) ◽  
pp. 220
Author(s):  
Ahmad Ali ◽  
Umme Rubab ◽  
Dinesh Kumar ◽  
MohammadAbul Farah ◽  
KhalidMashay Al-Anazi ◽  
...  
Keyword(s):  
Nigella Sativa ◽  
Nigella Sativa Seed ◽  
Seed Extracts

Exploring anti-yeast activity of Nigella sativa seed extracts

2015 ◽  
Vol 77 ◽  
pp. 624-630 ◽  
Author(s):  
N.H. Nadaf ◽  
S.S. Gawade ◽  
A.S. Muniv ◽  
S.R. Waghmare ◽  
D.B. Jadhav ◽  
...  
Keyword(s):  
Nigella Sativa ◽  
Nigella Sativa Seed ◽  
Seed Extracts

scholarly journals Assessment of Quinone Enriched Fraction in Nigella sativa Seed Extracts

2020 ◽  
Vol 11 (2) ◽  
pp. 1505-1510
Author(s):  
Durga B ◽  
Durga B ◽  
Dass Prakash M V ◽  
Julius A
Keyword(s):  
High Performance ◽  
Nigella Sativa ◽  
Ethanolic Extract ◽  
Ethanol Extract ◽  
Bioactive Compound ◽  
New Drugs ◽  
Natural Sources ◽  
Ethanolic Extracts ◽  
Nigella Sativa Seed ◽  
Seed Extracts

In recent days, the thirst for the identification of the potential bioactive compounds from the natural sources like medicinal plants is on continuous demand. Among scientists and academicians, it has created many interdisciplinary platforms for research in establishing new drugs from the natural sources. According to many recent studies, Nigella sativa is believed to be the rich source of quinone, an effective bioactive compound with lots of medicinal values. The purpose of this study was to isolate and estimate the quinone in Nigella sativa seed extracts (aqueous and ethanol). Based on the qualitative and quantitative determination, the extracts were further focused for isolation of quinone from both aqueous and ethanolic  extracts of Nigella sativa. The isolated compound is identified by thin layer chromatography and purity is analyzed in High performance liquid chromatography. From the results we obtained, it was very clear that among the aqueous and ethanolic extracts of Nigella sativa, the ethanolic extract has been found with the highest quantity of quinine. This would be predicting that the ethanol extract of Nigella sativa may have good efficacy of pharmacological and therapeutic potentials like antidiabetic, anticancer, antimicrobial, anti-inflammatory properties when compared with the aqueous extract due to the presence of more quinone.

In vitro anti-yeast effect of Nigella sativa seed quinones

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
K Halamova ◽  
J Flesar ◽  
J Malik ◽  
L Kokoska
Keyword(s):  
Nigella Sativa ◽  
Nigella Sativa Seed

scholarly journals Synthesis of silver nanoparticles using Nigella sativa seed extracts and assessment of their antibacterial activity

2020 ◽  
Vol 11 (2) ◽  
pp. 2525-2532
Author(s):  
Sheik Shehensha ◽  
Jyothi M V
Keyword(s):  
Silver Nanoparticles ◽  
Antibacterial Activity ◽  
Streptococcus Pyogenes ◽  
Nigella Sativa ◽  
Resistant Bacteria ◽  
Drug Resistant ◽  
Drug Resistant Bacteria ◽  
Resistant Strains ◽  
Nigella Sativa Seed ◽  
Seed Extracts

Silver nanoparticles were biosynthesized from Nigella sativa seed extracts using ethanol and chloroform. The antibacterial activity of silver nanoparticles against some drug-resistant bacteria has been established, but further study is needed to assess whether these particles could be an option for the treatment and prevention of drug-resistant microbial infections. Synthesized nanoparticles were characterized and screened for their antibacterial properties on resistant strains. The biosynthesized silver nanoparticles were characterized by UV-Visible, FTIR, Dynamic light scattering and Scanning Electron Microscope (SEM) analysis. The antibacterial action of biosynthesized silver nanoparticles was assessed by Microtitre Broth dilution process using Ciprofloxacin as standard, against resistant strains like Pseudomonas aeruginosa, Clostridium difficile, Klebsiella pneumoniae and Streptococcus pyogenes. The Silver nanoparticles obtained from chloroform extract of Nigella sativa seeds were more effective against Pseudomonas aeuruginosa, Clostridium difficile and Streptococcus pyogenes; than ethanolic seed extracts at 120 µL. Our data propose that the silver nanoparticles are effective against a variety of drug-resistant bacteria, which makes them a potential candidate for use in pharmaceutical products that may help to treat drug-resistant pathogens in different clinical environments. The present study focuses on the ability of phytoconstituents capped with silver nitrate can be used to treat infections caused by resistant bacteria

Nigella sativa seed extracts enhance glucose-induced insulin release from rat-isolated Langerhans islets

2004 ◽  
Vol 18 (5) ◽  
pp. 525-529 ◽  
Author(s):  
Halima Rchid ◽  
Hugues Chevassus ◽  
Rachid Nmila ◽  
Carine Guiral ◽  
Pierre Petit ◽  
...  
Keyword(s):  
Insulin Release ◽  
Nigella Sativa ◽  
Langerhans Islets ◽  
Nigella Sativa Seed ◽  
Seed Extracts

scholarly journals First Report in Sudan: Detection of Antibacterial Activity of the Black Cumin (Nigella sativa) Seed Extract against Mycoplasma mycoides subsp mycoides (Mmm)

2019 ◽  
pp. 1-6
Author(s):  
Raghad A. H. Onsa ◽  
E. A. Muna ◽  
Samia A. A. Hassan
Keyword(s):  
Seed Oil ◽  
Nigella Sativa ◽  
Local Strain ◽  
Bactericidal Effect ◽  
Black Cumin ◽  
Veterinary Research ◽  
Mycoplasma Mycoides ◽  
Inhibition Zones ◽  
Nigella Sativa Seed

Aims: This study was focused on the effect of Nigella sativa seed oil on the in vitro growth of Mycoplasma mycoides subsp mycoides (Mmm). Study Design: Three strains of (Mmm) were subjected to different dilutions of extracted Nigella sativa seed oil and the inhibitory zones were recorded. Type of effect (bactericidal or bacteriostatic) was studied. Place and Duration of Study: The study was carried out at Mycoplasma and biochemistry departments Central Veterinary Research Laboratory (CVRL) - 2018. Methodology: The tested strains were: Reference strain (T1/44), recent local strain (RH strain) and the last one was an old local strain (F strain). Different dilutions were used from N. sativa (25%, 50%, 75% and 100%) respectively. Results: The N. sativa revealed different inhibition zones on the growth of the three mentioned cultures. In addition to that bactericidal effect on (Mmm) growth was observed. Conclusion: The result of this study suggests the potential use of Cumin seed (N. sativa) against (Mmm) in vitro, and this result contributes in CBPP disease control using this type of natural seeds.

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