Reduction of Vaginal Bleeding Following Surgical Evacuation for First Trimester Abortion with Oral Misoprostol: A Randomized Placebo-Controlled Study

2016 ◽  
Vol 6 ◽  
pp. 1-6
Author(s):  
Hesham M. Borg and Ayman Shehata
Keyword(s):  
Vaginal Bleeding ◽  
First Trimester ◽  
Controlled Study ◽  
Trimester Abortion ◽  
Oral Misoprostol ◽  
Surgical Evacuation

scholarly journals Maternal and perinatal outcomes in women with first trimester vaginal bleeding

2019 ◽  
Vol 8 (11) ◽  
pp. 4320
Author(s):  
K. Suganya ◽  
Latha Maheswari Subbarayan
Keyword(s):  
Pregnant Women ◽  
Vaginal Bleeding ◽  
Case Control Study ◽  
Preterm Labour ◽  
Perinatal Outcomes ◽  
First Trimester ◽  
Case Control ◽  
Second Trimester ◽  
Trimester Abortion ◽  
Control Study

Background: First trimester bleeding is one of the common complications during pregnancy which affects almost 16-25% of all pregnancies. To evaluate and ascertain the adverse maternal and perinatal outcomes in pregnant women presenting with first trimester vaginal bleeding.Methods: Prospective case-control study. A case control study involving 60 pregnant women with vaginal bleeding in the first 13 weeks + 6 days of gestational age with 60 matched controls. The study period was from March 2015 to March 2016 and conducted at PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu.Results: The complications seen in the study group were: first trimester abortion (16.7%), second trimester abortion (6.7%), preterm labour (25%), abruption (6.7%), neonatal intensive care admission (25%), ectopic (6.7%), IUGR (10%), IUD (1.7%) and PROM (8.3%). When compared with the parity matched controls there was statistically significant increase in first and second trimester abortions, preterm labour, abruption, NICU admission and ectopic pregnancy whereas there was no significant difference between the two groups with regard to intrauterine growth restriction (IUGR) and intrauterine death (IUD).Conclusions: Women with first trimester vaginal bleeding had several adverse outcomes in both the mother and the fetus, and it is very important to explain about the possibility of these outcomes and ensure proper follow up with close antenatal surveillance.

scholarly journals Comparative study of efficiency of vaginal versus oral misoprostol along with mifepristone for first trimester medical termination of pregnancy

2019 ◽  
Vol 8 (6) ◽  
pp. 2322
Author(s):  
Latika R. Mehta ◽  
Grishma P. Agrawal
Keyword(s):  
Side Effects ◽  
Tertiary Care ◽  
First Trimester ◽  
Termination Of Pregnancy ◽  
Trimester Abortion ◽  
Drug Effectiveness ◽  
Oral Misoprostol ◽  
Oral Group ◽  
Vaginal Misoprostol ◽  
Set Up

Background: Authors estimate that 15.6 million abortions (14.1 million-17.3 million) occurred in India in 2015. Incomplete abortion is a known disadvantage of medical method of abortion reported in 0.2-3% of cases. Though Misoprostol can be used with different routes including oral, sublingual and vaginal, few evidences are available in drug effectiveness as well as its related side effects when used through different routes and more so in India. The present study is aimed to compare the efficacy of misoprostal in first trimester abortion when taken vaginally as compared to orally. Thus, whichever route results in lower rates of incomplete abortions, can be employed in our health set up, minimizing the complications of failed first trimester MTP.Methods: An experimental study was conducted on 74 women seeking termination of pregnancy within 9 weeks of amenorrhea during the period of 9 months in a tertiary care institute. Tablet mifepristone 200 mg was given to all participants. After 48 hours, 37 women were given 800 mcg tablet of Misoprostol for oral consumption while other 37 women were given 800 mcg Misoprostol for self-administering vaginally. Abortion status and complications were checked.Results: The complete abortion rates in vaginal group and oral group were 97.3% and 86.49 % respectively. Satisfaction was more in case of vaginal misoprostol, while side effects were similar in both groups.Conclusions: Mifepristone with vaginal misoprostol was more effective as compared to oral misoprostol for first trimester abortion.

scholarly journals A molar pregnancy detected by following irregular vaginal bleeding after a first trimester evacuation: rare case report

2019 ◽  
Vol 8 (6) ◽  
pp. 2549
Author(s):  
Meena Bhati Salvi
Keyword(s):  
Case Report ◽  
Vaginal Bleeding ◽  
Transvaginal Ultrasound ◽  
Correct Diagnosis ◽  
First Trimester ◽  
Molar Pregnancy ◽  
Sequence Of Events ◽  
Beta Hcg ◽  
Surgical Evacuation ◽  
Invasive Mole

In this case report summarizes the sequence of events that led to detection of a molar pregnancy missed by ultrasound and initial pathology examination. A 29 years old Asian nulliparous patient came to our clinic with missed period. On beta HCG she was 6 weeks pregnant. After 20 days she was diagnosed with 7 weeks missed abortion on ultrasound. surgical evacuation done for same. After 3 weeks she came with irregular vaginal bleeding. After physical and vaginal examination Beta HCG done, which was very high. On transvaginal ultrasound partial molar pregnancy was detected, so she was immediately admitted and repeat surgical evacuation was done. Histopathology report confirmed partial molar pregnancy which was not detected in previous report. She was regularly followed up with Beta HCG value up to 1 year which declined dramatically. Though molar pregnancy is rare, but it has the potential to develop into invasive mole, so any abnormal bleeding post evacuation should be followed up properly. Beta HCG values and histopathological evaluation is important for correct diagnosis and follow up.

Manual Versus Electric Vacuum Aspiration for Early First-Trimester Abortion: A Controlled Study of Complication Rates

2004 ◽  
Vol 103 (1) ◽  
pp. 101-107 ◽  
Author(s):  
Alisa B. Goldberg ◽  
Gillian Dean ◽  
Mi-Suk Kang ◽  
Sarah Youssof ◽  
Philip D. Darney
Keyword(s):  
First Trimester ◽  
Controlled Study ◽  
Complication Rates ◽  
Trimester Abortion ◽  
Vacuum Aspiration ◽  
Electric Vacuum

scholarly journals Comparison of sublingual, vaginal, and oral misoprostol in cervical ripening for first trimester abortion

2011 ◽  
Vol 43 (2) ◽  
pp. 172 ◽  
Author(s):  
VishalR Tandon ◽  
S Hakak ◽  
Z Singh ◽  
Shagufta Yasmeen ◽  
ShakeelA Mir ◽  
...  
Keyword(s):  
First Trimester ◽  
Cervical Ripening ◽  
Trimester Abortion ◽  
Oral Misoprostol

scholarly journals Fetomaternal outcome of pregnancy complicated by first and second trimester vaginal bleeding

2021 ◽  
Vol 10 (5) ◽  
pp. 1953
Author(s):  
Bhamini Jakhetiya ◽  
Ruhina Khan ◽  
Arun Gupta ◽  
Rama Chundawat ◽  
Meenakshi Singh
Keyword(s):  
Risk Factor ◽  
Vaginal Delivery ◽  
Vaginal Bleeding ◽  
Caesarean Delivery ◽  
Birth Asphyxia ◽  
First Trimester ◽  
High Rate ◽  
Second Trimester ◽  
Trimester Abortion ◽  
Nicu Admission

Background: To determine the effects of vaginal bleeding occurring in first and second trimester on maternal and fetal outcome.Methods: The present prospective observational study was conducted at department of obstetrics and gynecology, Geetanjali medical college and hospital, Udaipur and 90 Patients with first and second trimester pregnancy (till 24 weeks of gestation) presented with  the complaint of vaginal bleeding at antenatal clinic or emergency were included in this study.Results: In our study the result showed that bleeding in early pregnancy is associated with high rate of abortion (32.22%) in which first trimester abortion constitute 44.83% while second trimester abortion constitute around 55.17%.  Outcome observed in women having bleeding with SCH 58.4% had caesarean delivery followed by 25% had vaginal delivery, 16.7% had preeclampsia, 8.3% had PPROM and 5.6% had APH. Similarly, in women having bleeding without SCH 64% had caesarean delivery followed by 36% had vaginal delivery, 12% had preeclampsia, PPROM and APH in 8% each  and also women having bleeding with SCH, 37.1% had low birth babies, 22.8% had NICU admission and 8.6% had birth asphyxia. Similarly, in women having bleeding without SCH, 16% had low birth babies, 16% had NICU admission and 8% had birth asphyxia.Conclusions: First and second trimester vaginal bleeding is an independent risk factor for an adverse obstetric outcome and this risk factor should be taken into consideration when deciding upon antenatal surveillance and management.

scholarly journals First trimester bleeding and pregnancy outcome

2017 ◽  
Vol 6 (4) ◽  
pp. 1484
Author(s):  
Pradnya Digambar Kamble ◽  
Amarjeetkaur Bava ◽  
Mansi Shukla ◽  
Y. S. Nandanvar
Keyword(s):  
Vaginal Bleeding ◽  
Tertiary Care ◽  
First Trimester ◽  
Care Hospital ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Trimester Abortion ◽  
Uterine Growth ◽  
Fetal Complications ◽  
One Year

Background: The outcome of first trimester vaginal bleeding is a matter of debate. This study sought to determine the maternal and perinatal outcome in patients presenting with first trimester vaginal bleeding.Methods: This prospective observational study was done on 1007 women with first trimester vaginal bleeding at a tertiary care hospital in Mumbai over a period of one year. A detailed history was taken and USG was done to confirm diagnosis. All these patients were evaluated for the outcomes including  threatened abortions, spontaneous, complete or incomplete abortions, sub-chorionic hematoma, Intra-uterine Fetal Demise, missed abortions, second and third trimester bleeding, Intra-uterine Growth Restriction, premature rupture of membranes and preterm deliveries.Results: Out of the 11835 confinements 1007 patients presented with first trimester vaginal bleeding. The incidence was highest (52.3%) in the age group of 21-30 years. 63.9% primigravidas presented with first trimester bleeding as compared to 36.1% of multigravidas.  It was seen that 76.9% patients who presented before 6 weeks aborted whereas only 7% patients who presented after 10 weeks aborted. Out of the 163 patients that continued pregnancy after first trimester vaginal bleeding 1.8% had a second trimester abortion, 15.3% went into preterm labour 6.75% has premature rupture of membranes and 1.8% had antepartum hemorrhage.Conclusions: According to the results of present study, first trimester vaginal bleeding predicts auxiliary maternal and fetal complications. Also, as the clinical intermediation has an important role in continuance of pregnancy and in reducing the fetal complications precise management and planning by physician is important.

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