scholarly journals Multiple Roles of the PI3K/PKB (Akt) Pathway in Cell Cycle Progression

Cell Cycle ◽  
2003 ◽  
Vol 2 (4) ◽  
pp. 336-342 ◽  
Author(s):  
Jiyong Liang ◽  
Joyce M. Slingerland
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Progression ◽  
Multiple Roles ◽  
Akt Pathway ◽  
Cycle Progression

scholarly journals Exogenous hydrogen sulfide exerts proliferation, anti-apoptosis, migration effects and accelerates cell cycle progression in multiple myeloma cells via activating the Akt pathway

2016 ◽  
Vol 36 (4) ◽  
pp. 1909-1916 ◽  
Author(s):  
Dong Zheng ◽  
Ziang Chen ◽  
Jingfu Chen ◽  
Xiaomin Zhuang ◽  
Jianqiang Feng ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Multiple Myeloma ◽  
Hydrogen Sulfide ◽  
Cell Cycle Progression ◽  
Akt Pathway ◽  
Cycle Progression ◽  
Myeloma Cells

scholarly journals The Multiple Roles of the Cdc14 Phosphatase in Cell Cycle Control

2020 ◽  
Vol 21 (3) ◽  
pp. 709
Author(s):  
Javier Manzano-López ◽  
Fernando Monje-Casas
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Progression ◽  
Current Knowledge ◽  
Cell Cycle Control ◽  
Multiple Roles ◽  
Special Focus ◽  
Cyclin Dependent Kinase ◽  
Yeast Saccharomyces Cerevisiae ◽  
Cycle Progression

The Cdc14 phosphatase is a key regulator of mitosis in the budding yeast Saccharomyces cerevisiae. Cdc14 was initially described as playing an essential role in the control of cell cycle progression by promoting mitotic exit on the basis of its capacity to counteract the activity of the cyclin-dependent kinase Cdc28/Cdk1. A compiling body of evidence, however, has later demonstrated that this phosphatase plays other multiple roles in the regulation of mitosis at different cell cycle stages. Here, we summarize our current knowledge about the pivotal role of Cdc14 in cell cycle control, with a special focus in the most recently uncovered functions of the phosphatase.

scholarly journals Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy

Leukemia ◽  
2003 ◽  
Vol 17 (3) ◽  
pp. 590-603 ◽  
Author(s):  
F Chang ◽  
J T Lee ◽  
P M Navolanic ◽  
L S Steelman ◽  
J G Shelton ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cancer Chemotherapy ◽  
Cell Cycle Progression ◽  
Neoplastic Transformation ◽  
Akt Pathway ◽  
Cycle Progression
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