Methanol Extracts of Medicinal Plants Used for Oral Healthcare in Cameroon

Author(s):  
Ashu Michael Agbor
2021 ◽  
Vol 16 (7) ◽  
pp. 15-22
Author(s):  
Paul Giftson ◽  
Jerrine Joseph ◽  
Revathy Kalyanasundaram ◽  
V. Ramesh Kumar ◽  
Wilson Aruni

Tuberculosis (TB) is a communicable disease and remains one of the top 10 causes of death worldwide. One fourth of the world population is infected with TB at a risk of developing disease. The increase in the incidence of drug resistant TB around the world urges the need to develop a new candidate to fight against the disease. Plants were considered as the rich source of bioactive components to be used as potential drugs. Medicinal plants are used in pure as well as crude materials for their medicinal properties. Our research aims in identifying the phyto-molecules which have anti- tuberculosis property. Four medicinal plants namely, Acalyphaciliata (Kuppaimeni), Solanumtrilobatum (Thuthuvalai), Momordicacharantia (Bitter Gourd) and Sennaauriculata (Avaram) were chosen to evaluate their antimicrobial activity focusing on anti-tubercular activity. The methanol extracts of the medicinal plants showed significant inhibitory activity against bacterial and fungal pathogens. Sennaauriculata methanol extracts showed activity against S. aureus, E. coli, P. aeruginosa and C. albicans. In the screening of antimycobacterial activity done by LRP assay, among the plant extracts tested, the hexane crude extracts of Momordicacharantia (Bitter Gourd) showed 82.2% and 81.03% of inhibition against M. tuberculosis H37Rv at 500µg/ml and 250µg/ml concentration respectively. Similarly, the methanol crude extracts of Momordicacharantia showed 87.14% and 63.55% of inhibition at 500µg/ml and 250µg/ml concentration respectively.


2021 ◽  
Vol 10 (3) ◽  
pp. 281-288
Author(s):  
Aswin Rafif Khairullah ◽  
Tridiganita Intan Solikhah ◽  
Arif Nur Muhammad Ansori ◽  
Ristag Hamida Hanisia ◽  
Gavrila Amadea Puspitarani ◽  
...  

Kaempferia galanga included in the Zingiberaceae family is one of the potential medicinal plants with aromatic rhizome. In traditional medicine in Asian countries, this plant is widely used by local practitioners. This plant is widely cultivated in most Southeast Asian countries such as Cambodia, Vietnam, Malaysia, Thailand, and Indonesia. Ethyl-para-methoxycinnamate and ethyl-cinnamate are found as the main compounds in hexane, dichloromethane, and methanol extracts of K. galanga. This plant is traditionally used as an expectorant, stimulant, diuretic, carminative, and antipyretic remedy. In addition, K. galanga is used for treatment of diabetes, hypertension, cough, asthma, joint fractures, rheumatism, urticaria, vertigo, and intestinal injuries. Therefore, this study aimed to give a sneak peek view on galangal’s ethnobotany, toxicology, pharmacology, and phytochemistry.


Pharmacologia ◽  
2017 ◽  
Vol 8 (2) ◽  
pp. 78-82 ◽  
Author(s):  
Md. Jakaria ◽  
Mukimul Islam ◽  
Md. Shariful I ◽  
Mohammad Belal Talu ◽  
Chayan Dhar Clint ◽  
...  

2012 ◽  
Vol 22 (1) ◽  
pp. 9-15 ◽  
Author(s):  
Sanjay Guleria ◽  
A. K. Tiku ◽  
Gurjinder Singh ◽  
Apurva Koul ◽  
Sahil Gupta ◽  
...  

2011 ◽  
Vol 27 (1) ◽  
pp. 31-36 ◽  
Author(s):  
Chang-Geun Kang ◽  
Dae-Sik Hah ◽  
Chung-Hui Kim ◽  
Young-Hwan Kim ◽  
Eui-Kyung Kim ◽  
...  

2013 ◽  
Vol 56 (4) ◽  
pp. 199-204 ◽  
Author(s):  
Dang Minh Chanh Nguyen ◽  
Dong-Jun Seo ◽  
Ro-Dong Park ◽  
Woo-Jin Jung

2014 ◽  
Vol 9 (1) ◽  
pp. 1934578X1400900 ◽  
Author(s):  
Smart J. Mpofu ◽  
Omotayo A. Arotiba ◽  
Lerato Hlekelele ◽  
Derek T. Ndinteh ◽  
Rui W.M. Krause

In this work, we report the identification and quantification of catechins by electrochemistry and UV-Vis spectroscopy in Elephantorrhiza elephantina (Fabaceae) and Pentanisia prunelloides (Rubiaceae), both of which are medicinal plants that are widely used in Southern Africa to remedy various ailments. A comparative study of the catechin content as (-)-epicatechin equivalent is reported for the first time, with E. elephantina exhibiting a higher concentration relative to P. prunelloides in both aqueous and methanol extracts.


2019 ◽  
Vol 9 (4) ◽  
pp. 280-288
Author(s):  
Olugbenga K. Popoola ◽  
Francis J. Faleye ◽  
Folorunso A. Olabiyi ◽  
Olajide Ayodele

Background: Over exposure to Ultra Violet (UV) radiation is one of the most significant external stress-inducing factors resulting into occurrence of skin pigmentation among others in human body. The biological implication of such disorders is not only limited to premature skin aging and cancer, but also resulted into economic loss of perishable agricultural products. Methods: Methanol extracts of ten (10) medicinal plants with skin health traditional history were selected for this study. The biological profile of the extracts was assessed in an in-vitro system using colorimetric assays: tyrosinase inhibition, Ferric-ion Reducing Antioxidant Power (FRAP), Trolox Equivalent Absorbance Capacity (TEAC) and Fe II-induced microsomal lipid peroxidation. Results: Representative of asteraceae such as Laggera pterodonta (S3); Ageratum conyzoides (S4) and Chromolaena odorata (S5), while Euphorbia convoluloides (S8) were found to possess good anti- tyrosinase activity (IC50 = 177.50; 125.08; 167.58; 161.92) μg/ml respectively, in which the rate of formation of dopachrome proceeded via pseudo second order kinetic using the Largergren model. Other notable inhibition of oxidative stress displayed by the methanol extracts includes S7 (FRAP = 1905.12 ± 2.85 µM AAE/g); S1 & S6 (TEAC = 2163.48 ± 2.80; 1044.35 ± 28.99) µM TE/g, while S7 & S9 showed highest inhibitory activities on Fe II-induced microsomal lipid peroxidation (IC50 = 33.625; 35.125) µg/ml, respectively in competitive manner to that of the commercial anti-oxidant EGCG (IC50 = 36.250 µg/ml). Conclusion: The outcome of the biological properties of the selected plant extracts in this study suggested the existence of relationship between the traditional claims and the scientific data therein.


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