METABOLIC FACTOR: A STABLE MEASURE OF BIOLOGICAL PREDISPOSITION FOR OBESITY

2017 ◽  
Vol 06 (03) ◽  
Author(s):  
Brandon Davis
Keyword(s):  
Stable Measure ◽  
Metabolic Factor ◽  
Biological Predisposition

A Theory Model of the Existence Stable Measure for the Industrial Technology Innovation Strategy Alliance

2013 ◽  
Vol 401-403 ◽  
pp. 2193-2198
Author(s):  
Zhan Zhang ◽  
Bo Qin ◽  
Wei Dong Hu
Keyword(s):  
Risk Sharing ◽  
Technology Innovation ◽  
Theory Model ◽  
Innovation Strategy ◽  
Industrial Technology ◽  
Entropy Weight ◽  
Stable Measure ◽  
Measure Model ◽  
Entropy Weight Method ◽  
Questionnaire Method

This paper aims to establish a existence stable measure model. Use Alliance building, partner selection, the benefit and risk sharing, legal guarantee and policy guidance for one class index. Looking for data sources by Delphi method and questionnaire method and using the entropy weight method to Process those data. Through the model application can sum up the developing experience and provide reference for the Industrial technology innovation strategy alliances future development

Test–Retest Reliability of Dual-Recorded Brainstem versus Cortical Auditory-Evoked Potentials to Speech

2018 ◽  
Vol 29 (02) ◽  
pp. 164-174 ◽  
Author(s):  
Gavin M. Bidelman ◽  
Monique Pousson ◽  
Calli Dugas ◽  
Amy Fehrenbach
Keyword(s):  
Evoked Potentials ◽  
Auditory Evoked Potentials ◽  
Intraclass Correlation ◽  
Auditory Brainstem Responses ◽  
Single Subject ◽  
Neural Responses ◽  
Intrasubject Variability ◽  
Stable Measure ◽  
Retest Reliability ◽  
Test Retest Reliability

AbstractAuditory-evoked potentials have proven useful in the objective evaluation of sound encoding at different stages of the auditory pathway (brainstem and cortex). Yet, their utility for use in clinical assessment and empirical research relies critically on the precision and test–retest repeatability of the measure.To determine how subcortical/cortical classes of auditory neural responses directly compare in terms of their internal consistency and test–retest reliability within and between listeners.A descriptive cohort study describing the dispersion of electrophysiological measures.Eight young, normal-hearing female listeners.We recorded auditory brainstem responses (ABRs), brainstem frequency-following responses (FFRs), and cortical (P1-N1-P2) auditory-evoked potentials elicited by speech sounds in the same set of listeners. We reassessed responses within each of four different test sessions over a period of 1 mo, allowing us to detect possible changes in latency/amplitude characteristics with finer detail than in previous studies.Our findings show that brainstem and cortical amplitude/latency measures are remarkably stable; with the exception of slight prolongation of the P1 wave, we found no significant variation in any response measure. Intraclass correlation analysis revealed that the speech-evoked FFR amplitude and latency measures achieved superior repeatability (intraclass correlation coefficient >0.85) among the more widely used obligatory brainstem (ABR) and cortical (P1-N1-P2) auditory-evoked potentials. Contrasting these intersubject effects, intrasubject variability (i.e., within-subject coefficient of variation) revealed that while latencies were more stable than amplitudes, brainstem and cortical responses did not differ in their variability at the single subject level.We conclude that (1) the variability of auditory neural responses increases with ascending level along the auditory neuroaxis (cortex > brainstem) between subjects but remains highly stable within subjects and (2) speech-FFRs might provide a more stable measure of auditory function than other conventional responses (e.g., click-ABR), given their lower inter- and intrasubject variability.

Influence of ischemia on tissue androgens in eugonadal and androgen-deprived men treated with prostatectomy.

2013 ◽  
Vol 31 (6_suppl) ◽  
pp. 118-118 ◽  
Author(s):  
Robert B. Montgomery ◽  
Michael Christopher Risk ◽  
Daniel W. Lin ◽  
Alvin M. Matsumoto ◽  
Brett Marck ◽  
...  
Keyword(s):  
Linear Trend ◽  
Clinical Trial Design ◽  
Prostate Tissue ◽  
Lhrh Agonist ◽  
Time Intervals ◽  
Stable Measure ◽  
Ischemic Time ◽  
Treatment Groups ◽  
One Way Anova ◽  
Androgen Levels

118 Background: Optimizing tissue androgen suppression may provide a higher rate of complete pathologic response in patients with localized prostate cancer (PCa). The ability to accurately assess tissue androgens may be influenced by ischemic time and catabolism after devascularization. This study was performed to determine if ischemia influences tissue androgen in eugonadal men and in men treated with various types of neoadjuvant androgen deprivation (ADT). Methods: Eugonadal men (n=12) or men treated with neoadjuvant ADT using LHRH agonist and Casodex or LHRH agonist with Dutasteride, Casodex or all three with Ketoconazole (n=34) underwent prostatectomy for localized PCa. Tissue was acquired by needle biopsy at the time of ligation of the vascular pedicles, at prostate removal and at 30 minutes after prostate removal. Prostate tissue was flash-frozen and tissue dihydrotestosterone (DHT) and testosterone (T) were determined by LC/MS/MS. Change in tissue androgens from clamp was assessed at each time point. Trends in androgen levels were assessed by ANOVA for eugonadal men and within each treatment group Results: Average time from clamp to removal was 23 minutes (± 8) and from removal to subsequent biopsy 32 minutes (± 2). There was no evidence for a significant change in T or DHT over the time intervals tested (one way ANOVA p>0.05 for all measures) except in patients treated with LHRH agonist and Casodex alone. In this group of patients, T declined by 34%by the time of prostate removal, and by 83% at 30 minutes after removal when compared to levels at clamp (one way ANOVA p=0.017, test for linear trend =0.007). In all other treatment groups, both T and DHT were stable for 60 minutes. Conclusions: Assessment of DHT levels in prostate tissue at prostatectomy is not compromised by ischemia. Tissue sampling from 30-60 minutes after vascular clamping yields a stable measure of tissue DHT in the majority of patients. In the absence of SRD5A blockade, testosterone sampling in castrate men is sensitive to ischemia, and delayed sampling underestimates tissue androgen levels due to ischemia-related metabolism. These results lend important insight into clinical trial design and translational endpoints.

Quantifying Coach Confirmation

2016 ◽  
Vol 5 (6) ◽  
pp. 751-769 ◽  
Author(s):  
Gregory A. Cranmer ◽  
Maria Brann ◽  
Keith Weber
Keyword(s):  
Factor Analysis ◽  
Fit Indices ◽  
Communication Research ◽  
Good Reliability ◽  
Stable Measure ◽  
Sport Communication ◽  
Psychological States ◽  
Confirmatory Factor ◽  
Pearson Correlations ◽  
Structurally Stable

The lack of appropriate measurement to assess athlete-coach interaction and athletes’ psychological states has historically plagued sport studies research (i.e., an encompassing term for sport psychology, management, sociology, and communication) and may partially explain the lack of empirical research regarding athlete-coach interaction within the emerging field of sport communication. Without valid and reliable tools to assess athlete-coach interactions, understanding the antecedents and outcomes of these relationships, which is a central aim of sport communication research, cannot be accomplished. This article develops and demonstrates validity for a measure of the coach confirmation instrument (CCI) via two studies. In Study 1, an exploratory factor analysis and parallel analysis produced a 15-item, two-factor measure (challenge and acceptance). In Study 2, a confirmatory factor analysis confirmed this two-factor structure had an acceptable-to-good fit using a variety of fit indices. Additionally, preliminary degrees of validity for the CCI were demonstrated through Pearson correlations with athletes’ feeling of being confirmed, coach satisfaction, and perceptions of coach verbal aggression. Collectively, these studies indicate the CCI is a structurally stable measure, which demonstrates good reliability and initial degrees of face, concurrent, convergent, discriminant, and content validity.

One-Year Test-Retest Reliability of the Online Version of ImPACT in High School Athletes

2011 ◽  
Vol 39 (11) ◽  
pp. 2319-2324 ◽  
Author(s):  
R.J. Elbin ◽  
Philip Schatz ◽  
Tracey Covassin
Keyword(s):  
High School ◽  
Verbal Memory ◽  
Visual Memory ◽  
Online Version ◽  
Neurocognitive Performance ◽  
High School Athletes ◽  
Stable Measure ◽  
Motor Processing ◽  
Test Retest Reliability ◽  
The Impact

Background: The ImPACT (Immediate Post-Concussion Assessment and Cognitive Testing) neurocognitive testing battery is a popular assessment tool used for concussion management. The stability of the baseline neurocognitive assessment is important for accurate comparisons between postconcussion and baseline neurocognitive performance. Psychometric properties of the recently released online version of ImPACT have yet to be established; therefore, research evaluating the reliability of this measure is warranted. Purpose: The authors investigated the 1-year test-retest reliability of the ImPACT online version in a sample of high school athletes. Study Design: Case series; Level of evidence, 4 Methods: A total of 369 varsity high school athletes completed 2 mandatory preseason baseline cognitive assessments approximately 1 year apart as required by their respective athletics program. No diagnosed concussion occurred between assessments. Results: Intraclass correlation coefficients (ICCs) for ImPACT online indicated that motor processing speed (.85) was the most stable composite score, followed by reaction time (.76), visual memory (.70), and verbal memory (.62). Unbiased estimates of reliability were consistent with ICCs: motor processing speed (.85), reaction time (.76), visual memory (.71), and verbal memory (.62). Conclusion: The online ImPACT baseline is a stable measure of neurocognitive performance across a 1-year time period for high school athletes. These reliability data for online ImPACT are higher than the 2-year ICCs previously reported from the desktop version. Clinical Relevance: It is recommended that the ImPACT baseline assessment (both desktop and online) continue to be updated every 2 years. The online version of ImPACT appears to be a stable measure of neurocognitive performance over a 1-year period, and systematic evaluation of its stability over a 2-year period is warranted.

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