scholarly journals Effect of Zinc Sulphate (ZnSO4) on the Gall Bladder of Clarias batrachus (Linn. 1758)

2021 ◽  
Vol 21 (2) ◽  
pp. 75-81
Author(s):  
Saba Khursheed Khan ◽  
Irfan Ashraf Badroo
Keyword(s):  
Heavy Metal ◽  
Gall Bladder ◽  
Zinc Sulphate ◽  
Aquatic Organisms ◽  
Clarias Batrachus ◽  
Metal Exposure ◽  
Heavy Metal Exposure ◽  
Muscular Layer ◽  
Simultaneous Control ◽  
Mucosal Folds

Heavy metal exposure to biota has become a severe thread to the environment, as its bioaccumulation, toxicity and persistence is happing at an alarming rate. Heavy metal presence in water bodies has been reported by various researchers. Henceforth their exposure to aquatic organisms is certain. An investigation on the possible toxicological impact of Zinc sulphate on fish Clarias batrachus is carried out in laboratory. Histology of gall bladder was used as a marker for evaluation of toxicity after sub lethal exposure. Fish were exposed to sub-lethal concentrations of 5mg/L, 10mg/L and 15mg/L for 20 days. Simultaneous control was also maintained. Principle histological alterations were deformities in the normal structures of columnar epithelial line, muscular layer, and mucosal folds. 15mg/L and 20mg/L exposure of zinc sulphate altered the sub mucosa besides leading the formation of bile crystals, an indication of water loss. The severity of histopathology was exposure dependent. Histopathological alteration in gall bladder can be regarded as sensitive biomarkers of Zinc sulphate toxicological manifestations hence can be utilized for ecotoxicological biomonitoring of aquatic bodies.

Bioaccessibility-corrected health risk of heavy metal exposure via shellfish consumption in coastal region of China

2021 ◽  
Vol 273 ◽  
pp. 116529
Author(s):  
Minwei Chai ◽  
Ruili Li ◽  
Yuan Gong ◽  
Xiaoxue Shen ◽  
Lingyun Yu
Keyword(s):  
Heavy Metal ◽  
Health Risk ◽  
Coastal Region ◽  
Metal Exposure ◽  
Heavy Metal Exposure

scholarly journals Relationship between heavy metal exposure and type 2 diabetes: a large-scale retrospective cohort study using occupational health examinations

BMJ Open ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. e039541
Author(s):  
Jun Ho Ji ◽  
Mi Hyeon Jin ◽  
Jung-Hun Kang ◽  
Soon Il Lee ◽  
Suee Lee ◽  
...  
Keyword(s):  
Heavy Metals ◽  
Type 2 Diabetes ◽  
Heavy Metal ◽  
Cohort Study ◽  
Retrospective Cohort ◽  
Metal Exposure ◽  
Heavy Metal Exposure ◽  
Lead And Cadmium

ObjectivesTo investigate the associations between heavy metal exposure and serum ferritin levels, physical measurements and type 2 diabetes mellitus (DM).DesignA retrospective cohort study.SettingChangwon, the location of this study, is a Korean representative industrial city. Data were obtained from medical check-ups between 2002 and 2018.ParticipantsA total of 34 814 male subjects were included. Of them, 1035 subjects with lead exposure, 200 subjects with cadmium exposure and the 33 579 remaining were assigned to cohort A, cohort B and the control cohort, respectively. Data including personal history of alcohol and smoking, age, height, weight, the follow-up duration, haemoglobin A1c (HbA1c), fasting blood sugar (FBS), ferritin levels, and lead and cadmium levels within 1 year after exposure were collected.Primary outcome measureIn subjects without diabetes, changes in FBS and HbA1c were analysed through repeated tests at intervals of 1 year or longer after the occupational exposure to heavy metals.ResultsIn Cohort A, DM was diagnosed in 33 subjects. There was a significant difference in lead concentrations between the subjects diagnosed with DM and those without DM during the follow-up period (3.94±2.92 mg/dL vs 2.81±2.03 mg/dL, p=0.002). Simple exposure to heavy metals (lead and cadmium) was not associated with DM in Cox regression models (lead exposure (HR) 1.01, 95% CI: 0.58 to 1.77, p 0.971; cadmium exposure HR 1.48, 95% CI: 0.61 to 3.55, p=0.385). Annual changes in FBS according to lead concentration at the beginning of exposure showed a positive correlation (r=0.072, p=0.032).ConclusionOur findings demonstrated that simple occupational exposure to heavy metals lead and cadmium was not associated with the incidence of DM. However, lead concentrations at the beginning of the exposure might be an indicator of DM and glucose elevations.

scholarly journals Environmental Heavy Metal Exposure and Chronic Kidney Disease in the General Population

2015 ◽  
Vol 30 (3) ◽  
pp. 272 ◽  
Author(s):  
Nam Hee Kim ◽  
Young Youl Hyun ◽  
Kyu-Beck Lee ◽  
Yoosoo Chang ◽  
Seungho Rhu ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Heavy Metal ◽  
Kidney Disease ◽  
General Population ◽  
Metal Exposure ◽  
Heavy Metal Exposure

Prospective associations between environmental heavy metal exposure and renal outcomes in adults with chronic kidney disease

Nephrology ◽  
2018 ◽  
Vol 23 (9) ◽  
pp. 830-836 ◽  
Author(s):  
Chun-Chieh Tsai ◽  
Chia-Lin Wu ◽  
Chew-Teng Kor ◽  
Ie-Bin Lian ◽  
Chin-Hua Chang ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Heavy Metal ◽  
Kidney Disease ◽  
Metal Exposure ◽  
Heavy Metal Exposure ◽  
Renal Outcomes

Effect of Probiotic and Amla Powder Supplementation on Metabolic Profile and Milk Production of Summer Stressed Buffaloes Residing in Heavy Metal Polluted Areas of Ludhiana

2021 ◽  
Author(s):  
Pranesh V. Yeotikar ◽  
Shashi Nayyar ◽  
Chanchal Singh ◽  
C.S. Mukhopadhyay ◽  
Sandeep Sodhi Kakkar ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Heavy Metal ◽  
Milk Production ◽  
Metabolic Profile ◽  
Antioxidant Status ◽  
Live Cells ◽  
Metal Exposure ◽  
Heavy Metal Exposure ◽  
Exposed Area ◽  
Oral Supplementation

Background: Oxidative stress is a unified concept for the assessment of metabolic status of buffaloes affected by a cocktail of heavy metal exposure from environment and it may significantly affect the metabolic profile and milk production during summer season. The present study aimed at evaluation of effect of probiotic (Saccharomyces cerevisiae strain 1026) and amla powder (Embilica officinalis) supplementation on levels of heavy metals, antioxidant status, oxidative stress in lymphocytes, metabolic profile and milk production of summer stressed buffaloes exposed to environmental heavy metal pollution. Methods: Twenty summer stressed lactating Murrah buffaloes of the same age group, close parity and in early lactation from the heavy metal exposed area were divided into two groups: Control (without supplementation) and Treatment group (supplemented with Saccharomyces cerevisiae1026) @ 50 billion live cells / animal /day and Amla powder @ 86 mg/kg body weight for 30 days. Blood and milk samples were collected from both the groups on the day of starting of supplementation (i.e. day 0) and on there after days 15 and 30 and analyzed for antioxidant status, metabolic profile, milk yield and quality.Result: Oral supplementation of probiotic and amla powder for 30 days improved the antioxidant status, metabolic profile and milk production of summer stressed buffaloes residing in heavy metal exposed area. The percentage monetary gains from buffaloes fed probiotic and amla powder was 13.68% more as compared to control.

Association between Heavy Metal Exposure and Prevalence of Metabolic Syndrome in Adults of South Korea

2017 ◽  
Vol 7 (2) ◽  
pp. 172-178 ◽  
Author(s):  
Jae-man Lee ◽  
Kyo-jin Seok ◽  
Joo-young Ryu ◽  
Woo-sung Jung ◽  
Joon-beom Park ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Heavy Metal ◽  
South Korea ◽  
Metal Exposure ◽  
Heavy Metal Exposure
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