scholarly journals Comparative Studies of Some Novel Cu(II) Polymeric Complexes Derived from Cyanoacetylhydrazine (CAH; L). The Role of Solvents Used on the Structure and Geometry of the Isolated Cu<sup>2+</sup> Complexes

2021 ◽  
Vol 10 (04) ◽  
pp. 111-130
Author(s):  
Mohsen M. Mostafa
Keyword(s):  
Comparative Studies ◽  
Polymeric Complexes

Artificial RNA Editing with ADAR for Gene Therapy

2020 ◽  
Vol 20 (1) ◽  
pp. 44-54 ◽  
Author(s):  
Sonali Bhakta ◽  
Toshifumi Tsukahara
Keyword(s):  
Gene Therapy ◽  
Genetic Code ◽  
Molecular Mechanism ◽  
Rna Editing ◽  
Comparative Studies ◽  
Genetic Diseases ◽  
Adenosine Deaminases ◽  
Family Protein ◽  
Hydrolytic Deamination

Editing mutated genes is a potential way for the treatment of genetic diseases. G-to-A mutations are common in mammals and can be treated by adenosine-to-inosine (A-to-I) editing, a type of substitutional RNA editing. The molecular mechanism of A-to-I editing involves the hydrolytic deamination of adenosine to an inosine base; this reaction is mediated by RNA-specific deaminases, adenosine deaminases acting on RNA (ADARs), family protein. Here, we review recent findings regarding the application of ADARs to restoring the genetic code along with different approaches involved in the process of artificial RNA editing by ADAR. We have also addressed comparative studies of various isoforms of ADARs. Therefore, we will try to provide a detailed overview of the artificial RNA editing and the role of ADAR with a focus on the enzymatic site directed A-to-I editing.

scholarly journals Public Consciousness of Kazakhstan in Ethical and Aesthetic Measurement

Adam alemi ◽  
2020 ◽  
Vol 4 (86) ◽  
pp. 123
Author(s):  
G. Solovieva
Keyword(s):  
Comparative Studies ◽  
Social Consciousness ◽  
The Other ◽  
Leading Role ◽  
The Status ◽  
Aesthetic Consciousness ◽  
Public Consciousness ◽  
Ethical Component ◽  
The One

Ethical and aesthetic consciousness is considered in the article as a single phenomenon with a priority of the ethical component. The analysis is carried out in comparative studies of two methods: consideration of the topic in the mirror of modern literature of Kazakhstan as a form of public consciousness and study of the same problem in the mirror of sociological material. These approaches complement each other and make it possible to identify two levels of social consciousness in the ethical and aesthetic dimension: the existing and the due. Sociology enables analysis at the first level. Literature combines both the one and the other, emphasizing the level of due, transformation of reality and resolution of the indicated contradictions. As a result, it was found that the key construct of the ethical and aesthetic consciousness of Kazakhstanis is the idea of cohesion and unity of all ethnic groups with the leading role of the Kazakh people. This idea has the deepest moral meaning and at the same time has the status of beauty, i.e. character aesthetic. Discord is always ugly. Whereas, unity in its essence is beautiful, showing a combination of good and beauty.

scholarly journals O multiculturalismo na literatura para a juventude: tensões, negociações e resistências / The Multiculturalism in Literature for Youth: Tensions, Negotiations and Resistances

2014 ◽  
Vol 3 (1) ◽  
Author(s):  
Maria Auxiliadora Fontana Baseio ◽  
Maria Zilda da Cunha
Keyword(s):  
Comparative Studies ◽  
Contemporary Society ◽  
The Arts ◽  
Literary Art ◽  
Cultural Communities ◽  
Symbolic Production ◽  
Globalized World ◽  
Different Cultures

ABSTRACTIn fact, the cultural relationships between different groups are not something specific to contemporary society, but the globalized world is the place where cultural communities relate in a more intense and complex way. The dynamics of globalization approach groups of different cultures causing tensions and resistances. In the Arts, this phenomenon is represented in different ways. In Literature - in this case addressed to youth - understood as a cultural and symbolic production, there are various practices of meaning, which are responsible to build ways of seeing, being and living. These practices point out the perception of plural identities. Artists, with the construction of their aesthetic and political projects, can refuse hegemonic discourses, fighting against prejudice, disrespect, exclusion, denying the ideology based on dominant values. The main purpose of this study is to analyze, in the new perspectives of Comparative Studies, the role of literary art and their intercultural dialogues.RESUMOApesar de os entrecruzamentos culturais não serem algo específico da sociedade contemporânea, é neste mundo globalizado que as comunidades culturais se relacionam de maneira mais intensa e complexa. A dinâmica da globalização cada vez mais aproxima grupos de culturas diferentes, provocando tensões, negociações e resistências. No campo das artes, esse fenômeno cultural é representado de diferentes formas. Na literatura - neste caso a que se destina à juventude - compreendida como produção cultural e simbólica transformadora, agenciam-se práticas de significação, ou seja, formas de construir modos de ver, de ser e de estar no mundo que favorecem a percepção das identidades múltiplas. Pela elaboração de seus projetos - estético e político -, os artistas põem em revista os discursos hegemônicos, marcados muitas vezes pelo preconceito, pelo desrespeito, pela exclusão, desnudando relações de poder, classificações e rotulações instituídas a partir de uma ideologia forjada a partir de valores dominantes. O objetivo deste estudo é analisar, dentro das novas perspectivas dos Estudos Comparados, o papel da arte literária em seus diálogos interculturais.

Comparative studies on glial markers

1981 ◽  
Vol 95 (1) ◽  
pp. 167-180
Author(s):  
B. I. Roots
Keyword(s):  
Manduca Sexta ◽  
Comparative Studies ◽  
Nervous Tissue ◽  
Functional Role ◽  
Functional Interactions ◽  
Lower Vertebrates ◽  
Fresh Insight ◽  
Insight Into ◽  
Biochemical Differentiation

Macromolecular markers for glial cells have been sought for a variety of reasons. One of the earliest was the need for a means of assessing the purity of cell and subcellular fractions prepared from nervous tissue. While there is still a requirement for this kind of tool, emphasis has shifted towards seeking information on biochemical differentiation among cells and their functional interactions. A brief general review will be made of glial markers and two of these, 2′,3′-cyclic nucleotide 3′-phosphohydrolase (CNP) and glutamine synthetase (GS), will be considered in detail. Until recently studies of markers have been concentrated on the higher vertebrates and those on lower vertebrates and invertebrates have hardly begun. However, such comparative studies may lead to fresh insight into old problems. For example, CNP has long been regarded as a marker for myelin and oligodendrocytes but it has not been possible to attribute a functional role to it and its relation to myelination has remained obscure. The finding that it is present in the glia of a moth Manduca sexta which lacks myelin provides a stimulus for a fresh approach to the problem. Another example is provided by studies on GS. This enzyme is found in astrocyte feet and preliminary results indicate that it is localized also in the perineurial glia of Aplysia ganglia. These results lead to a reconsideration of the perennial question of the possible role of astrocyte feet in barrier mechanisms. Extension of comparative studies may not only raise new questions but also provide some answers.

A Role for Religion?

2021 ◽  
pp. 191-224
Author(s):  
Philip Kitcher
Keyword(s):  
Immanuel Kant ◽  
Comparative Studies ◽  
Secular Humanism ◽  
Role Of Religion

The perspective of the preceding chapters has been humanistic but non-religious. This chapter is concerned with the possible role of religion in education. Endeavoring to steer between two kinds of fundamentalists—those who view particular scriptures as morally authoritative, and the “new atheists” who aim to abolish religion entirely—it argues that the crucial insight (stemming from Immanuel Kant) is to recognize the priority of morality. Once that is appreciated, secular humanists can ally with devotees of any religion, provided that the faithful have reached an ecumenical stage of religious progress. The educational consequences allow religion a role in the classroom, for comparative studies that promote dialogue among religions (and between religions and forms of secular humanism), and that appreciate both the contributions and the blemishes of the world’s major religions.

The Role of Religious Ideas and the Use of Models in Max Weber's Comparative Studies of Non-Capitalist Societies

1970 ◽  
Vol 30 (1) ◽  
pp. 74-99 ◽  
Author(s):  
R. Stephen Warner
Keyword(s):  
Economic Theory ◽  
Political Science ◽  
Comparative Studies ◽  
Max Weber ◽  
Historical Sociology ◽  
Economic Life ◽  
Classical Economic ◽  
Use Of Models ◽  
Significant Question

The theme of this conference, “The Organizational Forms of Economic Life and Their Evolution,” implies a concern for specifying the limits of the applicability of classical and neo-classical economic theory. Presumably because we sociologists have been in the forefront of those who insist on the recognition of these limits, I have been asked to present a paper from the viewpoint of historical sociology. Now I suppose that your field and mine are alike in at least one respect: the infrequency of finding any one view on a broad and significant question. I am sure you will understand, therefore, my concentration on some lessons to be learned from the work of one of the heroes of my discipline, Max Weber (1864–1920). Weber, as you may know, was, among his other titles, a professor of economics and avoided the epithet of “sociologist.” Yet because sociology has changed since his day, largely under his influence, and because he was also a professor of law and of political science, we sociologists have now claimed him. Nevertheless, many of the issues that informed his massive scholarly research were and are issues central to both your field and mine.

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