On-Road Investigation of a Vehicle's Longitudinal Response to Wind Gusts

2008 ◽  
Author(s):  
Günter Bischof
Keyword(s):  
Longitudinal Response ◽  
Wind Gusts

scholarly journals Improvement Dependability of Offshore Horizontal-Axis Wind Turbines by Applying New Mathematical Methods for Calculation the Excess Speed in Case of Wind Gusts

Energies ◽  
2021 ◽  
Vol 14 (11) ◽  
pp. 3085
Author(s):  
Konstantin Osintsev ◽  
Seregei Aliukov ◽  
Alexander Shishkov
Keyword(s):  
Computer Simulation ◽  
Wind Turbines ◽  
Experimental Studies ◽  
Offshore Wind ◽  
Approximation Schemes ◽  
Calculation Error ◽  
Strong Wind ◽  
Mathematical Methods ◽  
Wind Gusts ◽  
Gas Dynamic

The problem of increasing the reliability of wind turbines exists in the development of new offshore oil and natural gas fields. Reducing emergency situations is necessary due to the autonomous operation of drilling rigs and bulk seaports in the subarctic and Arctic climate. The relevance of the topic is linked with the development of a methodology for theoretical and practical studies of gas dynamics when gas flows in a pipe, based on a mathematical model using new mathematical methods for calculation of excess speeds in case of wind gusts. Problems in the operation of offshore wind turbines arise with storm gusts of wind, which is comparable to the wave movement of the gas flow. Thus, the scientific problem of increasing the reliability of wind turbines in conditions of strong wind gusts is solved. The authors indicate a gross error in the calculations when approximating through the use of the Fourier series. The obtained results will allow us to solve one of the essential problems of modeling at this stage of its development, namely: to reduce the calculation time and the adequacy of the model built for similar installations and devices. Experimental studies of gas-dynamic flows are carried out on the example of a physical model of a wind turbine. In addition, a computer simulation of the gas-dynamic flow process was carried out. The use of new approximation schemes in processing the results of experiments and computer simulation can reduce the calculation error by 1.2 percent.

scholarly journals A Two-Stage Joint Model for Nonlinear Longitudinal Response and a Time-to-Event with Application in Transplantation Studies

2012 ◽  
Vol 2012 ◽  
pp. 1-18 ◽  
Author(s):  
Magdalena Murawska ◽  
Dimitris Rizopoulos ◽  
Emmanuel Lesaffre
Keyword(s):  
Empirical Bayes ◽  
Cox Model ◽  
Data Sets ◽  
Two Stage ◽  
Nonlinear Mixed Effects Model ◽  
Resistance Evolution ◽  
Longitudinal Response ◽  
Longitudinal Measurements ◽  
Subject Specific ◽  
The Impact

In transplantation studies, often longitudinal measurements are collected for important markers prior to the actual transplantation. Using only the last available measurement as a baseline covariate in a survival model for the time to graft failure discards the whole longitudinal evolution. We propose a two-stage approach to handle this type of data sets using all available information. At the first stage, we summarize the longitudinal information with nonlinear mixed-effects model, and at the second stage, we include the Empirical Bayes estimates of the subject-specific parameters as predictors in the Cox model for the time to allograft failure. To take into account that the estimated subject-specific parameters are included in the model, we use a Monte Carlo approach and sample from the posterior distribution of the random effects given the observed data. Our proposal is exemplified on a study of the impact of renal resistance evolution on the graft survival.

scholarly journals SAT0033 USING CHROMOSOME CONFORMATION FOR INSIGHT INTO PATHOGENESIS OF EARLY RHEUMATOID ARTHRITIS ENDOTYPES

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 946.2-947
Author(s):  
C. Duncan ◽  
E. Hunter ◽  
C. Koutsothanasi ◽  
M. Salter ◽  
A. Akoulitchev ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Disease Activity ◽  
Early Rheumatoid Arthritis ◽  
Inadequate Response ◽  
Loss Of Function ◽  
Inception Cohort ◽  
Chromosome Conformation ◽  
Patient Response ◽  
Early Ra ◽  
Longitudinal Response

Background:Rheumatoid arthritis (RA) is a chronic autoimmune disease with substantial immunopathogenic heterogeneity. It is well established that early diagnosis and initiation of effective therapy is crucial to prevent loss of function. Previously, various RA treatment trajectories have been identified, however there are currently no clinically validated biomarkers that can identify these trajectories at the start of treatment. Evaluation of the structural epigenome has revealed that chromosome conformation signatures (CCS) offer great potential as binary, informative biomarkers, and have been previously shown to predict early RA patient response to Methotrexate with 90% sensitivity (1). These signatures can also reveal highly regulated areas of the genome, which may be underpinning disease endotypes.Objectives:The objective of this study was to evaluate the structural epigenome in early RA over longitudinal samples to determine whether it is associated with treatment trajectories.Methods:Patient data and samples were from the Scottish Early Rheumatoid Arthritis (SERA) cohort; a pan-Scotland inception cohort. CDAI, DAS28 ESR and DAS28 CRP measurements were calculated at baseline, 6 months and 12 months to determine longitudinal treatment response. From 3 principal longitudinal response trajectories, 18 patients (who had equivalent disease activity at baseline) were chosen to investigate the structural epigenome. These 18 comprised of responders (R), non-responders (NR) and initial responders (IR; low disease activity/remission at 6 months but moderate/high disease activity at 12 months) with 6 patients per group at each time point. 20 pooled healthy samples were used as a comparator population. EpiSwitch libraries were probed on 180K Agilent SureSelect custom arrays that were designed using EpiSwitch propriety information and publicly available data from Walshet al(2). Microarray data was analysed using the Limma package within R studio.Results:EpiSwitch array analysis showed that there were >10,000 statistically significant differential chromosomal loops between R, NR and IR. Evaluation of the 3 trajectory groups (R, NR and IR), taking into account the healthy chromosomal conformation, revealed an RA-associated structural epigenome that comprised of 10,445 chromosomal loops that were stable, over the three time points. Subsequent analysis of the distinct treatment trajectories demonstrated that 3683 of the stable, disease-associated chromosomal loops were shared by all 3. However, 4496 were associated with distinct response trajectories, with 1221, 2574 and 701 loops unique to R, NR and IR respectively.Conclusion:The stable chromosomal architecture unique to each treatment trajectory suggests that various underlying molecular endotypes may exist. Moreover, the stable loops common to all groups allude to a baseline level of dysregulation in RA and offers the potential to discover novel drivers of disease. This work provides the foundation to further our understanding of RA pathogenesis and the potential of finding a biomarker that would be of significant value in a clinical setting.References:[1] Carini, C., Hunter, E., Scottish Early Rheumatoid Arthritis Inception cohort Investigators, Ramadass, A. S., Green, J., Akoulitchev, A., et al. (2018). Chromosome conformation signatures define predictive markers of inadequate response to methotrexate in early rheumatoid arthritis.Journal of Translational Medicine,16(1), 18–11[2] Walsh, A. M., Whitaker, J. W., Huang, C. C., Cherkas, Y., Lamberth, S. L., Brodmerkel, C., et al. (2016). Integrative genomic deconvolution of rheumatoid arthritis GWAS loci into gene and cell type associations.Genome Biology,17(1), 2205Disclosure of Interests:Caitlin Duncan: None declared, Ewan Hunter: None declared, Christina Koutsothanasi: None declared, Matthew Salter: None declared, Alexandre Akoulitchev: None declared, Iain McInnes Grant/research support from: Bristol-Myers Squibb, Celgene, Eli Lilly and Company, Janssen, and UCB, Consultant of: AbbVie, Bristol-Myers Squibb, Celgene, Eli Lilly and Company, Gilead, Janssen, Novartis, Pfizer, and UCB, Carl Goodyear: None declared

scholarly journals A Robust Control for an Aerial Robot Quadrotor under Wind Gusts

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Li Ding ◽  
Zhenwei Wang
Keyword(s):  
Parameter Tuning ◽  
Stability Control ◽  
Euler Method ◽  
Nonlinear Dynamical ◽  
Active Disturbance Rejection ◽  
Wind Gusts ◽  
Disturbance Rejection Control ◽  
Control Scheme ◽  
Aerial Robot ◽  
Linear Extended State Observer

A robust flight controller based on linear active disturbance rejection control (LADRC) is proposed for stability control of an aerial robot quadrotor under wind gusts. The nonlinear dynamical model of the quadrotor, considering the wind disturbance, is firstly established through Newton-Euler method. Subsequently, a robust LADRC technique is proposed to design the controllers for the inner loop and outer loop of the aircraft. In this control scheme, the linear extended state observer (LESO) serves as a compensator which can effectively reject the wind gusts. Then, a method of parameter tuning is introduced to obtain the optimized control performance. Finally, the effectiveness and advantages of the proposed controller are demonstrated through series of simulation case.

The Importance of Wind Gusts in Distributing Fungal Spores Among Crop Foliage

EPPO Bulletin ◽  
1983 ◽  
Vol 13 (2) ◽  
pp. 133-137 ◽  
Author(s):  
H.A. McCARTNEY ◽  
A. BAINBRIDGE ◽  
D.E. AYLOR
Keyword(s):  
Fungal Spores ◽  
Wind Gusts

Untersuchungen zur Ableitung von Windböen aus Doppler-Lidar-Messungen

2021 ◽  
Author(s):  
Carola Detring ◽  
Eileen Päschke ◽  
Julian Steinheuer ◽  
Ronny Leinweber ◽  
Markus Kayser ◽  
...  
Keyword(s):  
Field Experiment ◽  
Temporal Variability ◽  
Surface Wind ◽  
Doppler Lidar ◽  
Signal To Noise ◽  
Observation Volume ◽  
Wind Gusts ◽  
Die Profile ◽  
Spatio Temporal

<p>Mit Hilfe von Doppler-Lidar-Systemen, lassen sich die Profile von Windgeschwindigkeit und -richtung in der Atmosphärischen Grenzschicht (AGS) auf der Basis klassischer Messstrategien wie einem VAD-24 Scan (Velocity Azimuth Display mit 24 Strahlrichtungen) zuverlässig bestimmen (Päschke et al., 2015). Für praktische Anwendungen von großem Interesse sind jedoch neben dem mittleren Windprofil auch kurzzeitige Fluktuationen des Windes, wie sie zum Beispiel in Verbindung mit Windböen auftreten. Untersuchungen zu Windböen waren ein wesentlicher Aspekt der Messkampagne FESSTVaL (Field Experiment on Sub-Mesoscale Spatio-Temporal Variability in Lindenberg, www.fesstval.de).</p><p>Eine Studie von Suomi et al. (2017) hat gezeigt, dass eine Ableitung von Windböen aus Doppler Lidar Messungen prinzipiell möglich ist. Allerdings wird mit üblichen Messstrategien die hierfür erforderliche hohe zeitliche Auflösung in der Ermittlung des Windvektors nicht erreicht, so dass mit Skalierungsansätzen unter Verwendung von in-situ Windmessungen eine Korrektur der aus den Lidar-Daten abgeleiteten Böenwerte erfolgen muss.</p><p>Im Rahmen der vorliegenden Arbeit wurde eine alternative Messstrategie für Doppler-Lidar-Systeme vom Typ „Streamline“ (Halo Photonics) entwickelt und über mehrere Monate in den Jahren 2020/21 auf dem Grenzschichtmessfeld Falkenberg des DWD erprobt. Die Böenableitung basiert auf einem sog. Continous Scan Mode (CSM); dabei werden die während einer vollständigen Rotation des Lidar-Scan-Kopfes kontinuierlich durchgeführten Messungen 10-11 Strahlrichtungen zugeordnet und die Radialwindgeschwindigkeiten wiederum mit dem VAD-Verfahren ermittelt. Die Dauer eines Scans beträgt etwa 3.4s, damit kann eine Zeitauflösung erreicht werden, die der heute weit verbreiteten Definition einer Windbö entspricht (3s gleitendes Mittel; WMO (2018)).</p><p>Diese neue Konfiguration bringt Herausforderungen an die Datenverarbeitung mit sich. Im CSM muss mit vergleichsweise wenigen Lidar-Pulsen pro Messstrahl gearbeitet werden, so dass klassische Ansätze der Datenfilterung (Signal-to-Noise Schwellwert, Consensus Filterung) nicht verwendet werden können. Es wird ein alternatives Verfahren für die Prozessierung der Lidar-Rohdaten vorgeschlagen. Die Ergebnisse der Ableitung sowohl des mittleren Windvektors als auch der jeweiligen maximalen Windbö in einem 10-Minuten-Mittelungsintervall werden mit Sonic-Messungen in 90m Höhe verglichen. </p><p>Im Rahmen des FESSTVaL Experimentes wurde diese neue Messkonfiguration an drei Standorten, die ein annähernd gleichseitiges Dreieck mit einer Kantenlänge von etwa 5 km bildeten, genutzt. Es werden Fallbeispiele aus der FESSTVaL Kampagne für die Variabilität im Auftreten von Windböen gezeigt.</p><p><strong>Referenzen</strong></p><p>Päschke, E., Leinweber, R., and Lehmann, V. (2015): An assessment of the performance of a 1.5 μm Doppler lidar for operational vertical wind profiling based on a 1-year trial, Atmos. Meas. Tech., 8, 2251–2266, https://doi.org/10.5194/amt-8-2251-2015</p><p>Suomi, I., Gryning, S.‐E., O'Connor, E.J. and Vihma, T. (2017): Methodology for obtaining wind gusts using Doppler lidar. Q.J.R. Meteorol. Soc., 143: 2061-2072. https://doi.org/10.1002/qj.3059</p><p>World Meteorological Organization (WMO) (2018): Measurement of surface wind. In Guide to Meteorological Instruments and Methods of Observation, Volume I -Measurement of Meteorological Variables, No.8: 196–213, URL: https://library.wmo.int/doc_num.php?explnum_id=10616 (accessed November 2021)</p>

Midlatitude cyclones in convection permitting climate simulations: the added value offered for extreme wind speeds and sting-jets

2021 ◽  
Author(s):  
Colin Manning ◽  
Elizabeth Kendon ◽  
Hayley Fowler ◽  
Nigel Roberts ◽  
Segolene Berthou ◽  
...  
Keyword(s):  
Climate Model ◽  
Surface Wind ◽  
Added Value ◽  
Large Contribution ◽  
High Wind ◽  
Wind Speeds ◽  
Wind Gusts ◽  
Climate Simulations ◽  
Extreme Wind ◽  
Extreme Wind Speeds

<p>Extra-tropical windstorms are one of the costliest natural hazards affecting Europe, and windstorms that develop a phenomenon known as a sting-jet account for some of the most damaging storms. A sting-jet (SJ) is a mesoscale core of high wind speeds that occurs in particular types of cyclones, specifically Shapiro-Keyser (SK) cyclones, and can produce extremely damaging surface wind gusts. High-resolution climate models are required to adequately model SJs and so it is difficult to gauge their contribution to current and future wind risk. In this study, we develop a low-cost methodology to automate the detection of sting jets, using the characteristic warm seclusion of SK cyclones and the slantwise descent of high wind speeds, within pan-European 2.2km convection-permitting climate model (CPM) simulations. Following this, we quantify the contribution of such storms to wind risk in Northern Europe in current and future climate simulations, and secondly assess the added value offered by the CPM compared to a traditional coarse-resolution climate model. This presentation will give an overview of the developed methods and the results of our analysis.</p><p>Comparing with observations, we find that the representation of wind gusts is improved in the CPM compared to ERA-Interim reanalysis data. Storm severity metrics indicate that SK cyclones account for the majority of the most damaging windstorms. The future simulation produces a large increase (>100%) in the number of storms exceeding high thresholds of the storm metric, with a large contribution to this change (40%) coming from windstorms in which a sting-jet is detected. Finally, we see a systematic underestimation in the GCM compared to the CPM in the frequency of extreme wind speeds at 850hPa in the cold sector of cyclones, likely related to better representation of sting-jets and the cold conveyor belt in the CPM. This underestimation is between 20-40% and increases with increasing wind speed above 35m/s. We conclude that the CPM adds value in the representation of severe surface wind gusts, providing more reliable future projections and improved input for impact models.</p>

Length-tension relationship of vascular smooth muscle in single arterioles

1989 ◽  
Vol 256 (3) ◽  
pp. H630-H640 ◽  
Author(s):  
M. J. Davis ◽  
R. W. Gore
Keyword(s):  
Smooth Muscle ◽  
Vascular Smooth Muscle ◽  
Wall Stress ◽  
Physiological Saline ◽  
Intraluminal Pressure ◽  
Cheek Pouch ◽  
Hamster Cheek Pouch ◽  
Longitudinal Response ◽  
Physiological Saline Solution ◽  
Relationship Of

Longitudinal response gradients in the microcirculation may in part be explained in terms of the length-tension relationship of vascular smooth muscle at different points along the vascular tree. To test this hypothesis, four branching orders of arterial vessels (20-80 microns ID) were dissected from the hamster cheek pouch and cannulated with concentric micropipettes. Intraluminal pressure was monitored with a servo-null micropipette, and arteriolar dimensions were measured using a videomicrometer. All arterioles developed spontaneous tone in physiological saline solution. Pressure-diameter curves were recorded for maximally activated vessels and for passive vessels. Maximal active wall tension varied nearly threefold, but maximal active medial wall stress (approximately 4 x 10(6) dyn/cm2) varied only approximately 20% between the different vessel orders. These data support the concept that smooth muscle cells from vessels of different sizes are mechanically similar but do not completely explain the longitudinal response gradients reported in the cheek pouch microcirculation. An analysis of the effect of arteriolar wall buckling suggests that the luminal folds that develop at short vessel radii may broaden the peak of the active stress-length curve and extend the pressure range over which arterioles are most sensitive to physical and chemical stimuli.

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