Using a general purpose spreadsheet software package to estimate exponential plus constant model fits for blood lactate concentration versus work rate data

Author(s):  
Ian Cook ◽  
Gerrit J Van Wyk
1990 ◽  
Vol 68 (3) ◽  
pp. 905-911 ◽  
Author(s):  
S. Oyono-Enguelle ◽  
J. Marbach ◽  
A. Heitz ◽  
C. Ott ◽  
M. Gartner ◽  
...  

Venous lactate concentrations of nine athletes were recorded every 5 s before, during, and after graded exercise beginning at a work rate of 0 W with an increase of 50 W every 4th min. The continuous model proposed by Hughson et al. (J. Appl. Physiol. 62: 1975-1981, 1987) was well fitted with the individual blood lactate concentration vs. work rate curves obtained during exercise. Time courses of lactate concentrations during recovery were accurately described by a sum of two exponential functions. Significant direct linear relationships were found between the velocity constant (gamma 2 nu) of the slowly decreasing exponential term of the recovery curves and the times into the exercise when a lactate concentration of 2.5 mmol/l was reached. There was a significant inverse correlation between gamma 2 nu and the rate of lactate increase during the last step of the exercise. In terms of the functional meaning given to gamma 2 nu, these relationships indicate that the shift to higher work rates of the increase of the blood lactate concentration during graded exercise in fit or trained athletes, when compared with less fit or untrained ones, is associated with a higher ability to remove lactate during the recovery. The results suggest that the lactate removal ability plays an important role in the evolution pattern of blood lactate concentrations during graded exercise.


1989 ◽  
Vol 66 (3) ◽  
pp. 1104-1107 ◽  
Author(s):  
M. E. Campbell ◽  
R. L. Hughson ◽  
H. J. Green

The applicability of a continuous model description of the blood lactate concentration [( La-]) vs. O2 uptake (VO2) relationship was studied in nine healthy male volunteers during three different ramp exercise protocols. The work rate was increased at either 8, 15, or 50 W/min. The continuous model for [La-] = a + b exp(cVO2) was compared statistically with a previously proposed log-log transformation model for the [La-] and VO2 variables. It was found that the mean square error was significantly less for the continuous as opposed to the log-log model (P less than 0.01) by analysis of variance pooled across all three ramp slopes. The mean square errors from the individual ramp slopes were also significantly less for the continuous model by paired t test (P less than 0.05). It was observed that the major contributor to the increased error of the log-log model was at VO2's at or above the intersection point (lactate threshold) of the two linear log-transformed segments. The log-log transformation does not appear to relate to any physiological process. The lactate slope index, taken as the point where the slope of the relationship between [La-] and VO2 (i.e., d[La-]/dVO2) equaled 1, occurred at a mean VO2 of 2.25 and 2.37 l/min for the 15- and 8-W/min ramp slopes, respectively, but at 2.76 l/min for the 50-W/min ramp (P less than 0.05). It is concluded that [La-] increases as a continuous function with respect to VO2 across a wide range of ramp work rate slopes.


1998 ◽  
Vol 85 (6) ◽  
pp. 2118-2124 ◽  
Author(s):  
Veronique L. Billat ◽  
Ruddy Richard ◽  
Valerie M. Binsse ◽  
Jean P. Koralsztein ◽  
Philippe Haouzi

The purpose of this study was to examine the influence of the type of exercise (running vs. cycling) on the O2uptake (V˙o 2) slow component. Ten triathletes performed exhaustive exercise on a treadmill and on a cycloergometer at a work rate corresponding to 90% of maximalV˙o 2 (90% work rate maximalV˙o 2). The duration of the tests before exhaustion was superimposable for both type of exercises (10 min 37 s ± 4 min 11 s vs. 10 min 54 s ± 4 min 47 s for running and cycling, respectively). TheV˙o 2 slow component (difference between V˙o 2 at the last minute and minute 3 of exercise) was significantly lower during running compared with cycling (20.9 ± 2 vs. 268.8 ± 24 ml/min). Consequently, there was no relationship between the magnitude of theV˙o 2 slow component and the time to fatigue. Finally, because blood lactate levels at the end of the tests were similar for both running (7.2 ± 1.9 mmol/l) and cycling (7.3 ± 2.4 mmol/l), there was a clear dissociation between blood lactate and the V˙o 2slow component during running. These data demonstrate that 1) theV˙o 2 slow component depends on the type of exercise in a group of triathletes and 2) the time to fatigue is independent of the magnitude of theV˙o 2 slow component and blood lactate concentration. It is speculated that the difference in muscular contraction regimen between running and cycling could account for the difference in theV˙o 2 slow component.


2020 ◽  
Vol 19 (1) ◽  
pp. 32
Author(s):  
Gustavo Taques Marczynski ◽  
Luís Carlos Zattar Coelho ◽  
Leonardo Emmanuel De Medeiros Lima ◽  
Rodrigo Pereira Da Silva ◽  
Dilmar Pinto Guedes Jr ◽  
...  

The aim of this study was to analyze the influence of two velocities of execution relative to blood lactate concentration in strength training exercise until the momentary concentric failure. Fifteen men (29.1 ± 5.9 years), trained, participated in the experiment. The volunteers performed three bench press sessions, with an interval of 48 hours between them. At the first session, individuals determined loads through the 10-12 RMs test. In the following two sessions, three series with 90 seconds of interval were performed, in the second session slow execution speed (cadence 3030) and later in the third session fast speed (cadence 1010). For statistical analysis, the Student-T test was used for an independent sample study and considered the value of probability (p) ≤ 0.05 statistically significant. By comparing the number of repetitions and time under tension of the two runs, all series compared to the first presented significant reductions (p < 0.05). The total work volume was higher with the fast speed (p < 0.05). The study revealed that rapid velocities (cadence 1010) present a higher concentration of blood lactate when compared to slow runs (cadence 3030). The blood lactate concentration, in maximum repetitions, is affected by the speed of execution.Keywords: resistance training, cadence, blood lactate.


1993 ◽  
Vol 75 (6) ◽  
pp. 2727-2733 ◽  
Author(s):  
K. H. McKeever ◽  
K. W. Hinchcliff ◽  
D. F. Gerken ◽  
R. A. Sams

Four mature horses were used to test the effects of two doses (50 and 200 mg) of intravenously administered cocaine on hemodynamics and selected indexes of performance [maximal heart rate (HRmax), treadmill velocity at HRmax, treadmill velocity needed to produce a blood lactate concentration of 4 mmol/l, maximal mixed venous blood lactate concentration, maximal treadmill work intensity, and test duration] measured during an incremental treadmill test. Both doses of cocaine increased HRmax approximately 7% (P < 0.05). Mean arterial pressure was 30 mmHg greater (P < 0.05) during the 4- to 7-m/s steps of the exercise test in the 200-mg trial. Neither dose of cocaine had an effect on the responses to exertion of right atrial pressure, right ventricular pressure, or maximal change in right ventricular pressure over time. Maximal mixed venous blood lactate concentration increased 41% (P < 0.05) with the 50-mg dose and 75% (P < 0.05) with the 200-mg dose during exercise. Administration of cocaine resulted in decreases (P < 0.05) in the treadmill velocity needed to produce a blood lactate concentration of 4 mmol/l from 6.9 +/- 0.5 and 6.8 +/- 0.9 m/s during the control trials to 4.4 +/- 0.1 m/s during the 200-mg cocaine trial. Cocaine did not alter maximal treadmill work intensity (P > 0.05); however, time to exhaustion increased by approximately 92 s (15%; P < 0.05) during the 200-mg trial.(ABSTRACT TRUNCATED AT 250 WORDS)


Animals ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 743
Author(s):  
Francesca Arfuso ◽  
Claudia Giannetto ◽  
Elisabetta Giudice ◽  
Francesco Fazio ◽  
Michele Panzera ◽  
...  

The current study aimed to investigate whether peripheral modulators of serotoninergic function and neurohumoral factors’ changes in athletic horses during an official jumping competition, and to evaluate their relationship with the physical performance of competing horses. From 7 Italian Saddle mares (6–9 years; mean body weight 440 ± 15 kg), performing the same standardized warm-up and jumping course during an official class, heart rate (HR) was monitored throughout the competition. Rectal temperature (RT) measurement, blood lactate and glucose concentration, serum tryptophan, leucine, valine, the tryptophan/branched-chain amino-acids ratio (Try/BCAAs), dopamine, prolactin, and non-esterified fatty acids (NEFAs) were assessed before the exercise event (T0), at the end of the competition stage (5 min ± 10 s following the cessation of the exercise, TPOST5), and 30 min after the end of competition (TPOST30). Highest HR values were recorded during the course and at the outbound (p < 0.0001); blood lactate concentration and RT increased after exercise with respect to the rest condition (p < 0.0001). Lower leucine and valine levels (p < 0.01), and higher tryptophan, Try/BCAAs ratio, and NEFAs values were found at TPOST5 and TPOST30 with respect to T0 (p < 0.0001). A higher prolactin concentration was found at TPOST5 and TPOST30 compared to T0 (p < 0.0001), whereas dopamine showed decreased values after exercise compared to rest (p < 0.0001). Statistically significant correlations among the peripheral indices of serotoninergic function, neurohumoral factors, and athletic performance parameters were found throughout the monitoring period. The findings provide indirect evidence that the serotoninergic system may be involved in fatigue during jumper exercise under a stressful situation, such as competition, in which, in addition to physical effort, athletic horses exhibit more passive behavior.


2011 ◽  
Vol 6 (3) ◽  
pp. 419-426 ◽  
Author(s):  
Dale I. Lovell ◽  
Dale Mason ◽  
Elias Delphinus ◽  
Chris McLellan

Purpose:The aim of this study was to compare asynchronous (AS Y) arm cranking (cranks at 180° relative to each other) with synchronous (SYN) arm cranking (parallel crank setting) during the 30 s Wingate anaerobic test.Methods:Thirty-two physically active men (aged 22.1 ± 2.4 y) completed two Wingate tests (one ASY and one SYN) separated by 4 d in a randomized counterbalanced order. The Wingate tests were completed on a modified electromagnetically braked cycle ergometer. Performance measures assessed during the two tests include peak power, mean power, minimum power, time to peak power, rate to fatigue and maximum cadence (RPMmax). Blood lactate concentration was also measured before and 5 min after the tests.Results:Peak and mean power (both absolute and relative to body weight) during SYN arm cranking were significantly (p < 0.001) less than during ASY arm cranking. Rate to fatigue and RPMmax were also significantly (p = 0.012) lower during SYN arm cranking compared with ASY arm cranking. No significant difference was found between test conditions for minimum power, time to peak power or blood lactate concentration.Conclusions:These findings demonstrate that ASY arm cranking results in higher peak and mean anaerobic power compared with SYN arm cranking during the Wingate test. Therefore, an ASY arm crank configuration should be used to assess anaerobic power in most individuals although specific population groups may require further testing to determine which crank configuration is most suitable for the Wingate test.


2017 ◽  
Vol 12 (4) ◽  
pp. 527-532 ◽  
Author(s):  
F. Javier Núñez ◽  
Luis J. Suarez-Arrones ◽  
Paul Cater ◽  
Alberto Mendez-Villanueva

The aim of this study was to examine the kinematics and kinetics (force, velocity, and acceleration) and blood lactate concentration with the VersaPulley (VP) device in comparison with free-weight (FW) exercise at a similar external load. Fifteen rugby players randomly performed 2 training sessions of 6 sets of 6 repetitions with 20 s of recovery between sets of the high-pull exercise with the VP and the FW. The training sessions were separated by 72 h. Barbell displacement (cm), peak velocity (m/s), peak acceleration (m/s2), mean propulsive velocity (m/s), mean propulsive acceleration (m/s2), propulsive phase (%), and mean and maximal force (N) were continuously recorded during each repetition. Blood lactate concentration was measured after each training session (end) and 3 min and 5 min later. Barbell displacement (+4.8%, small ES), peak velocity (+4.5% small ES), mean propulsive acceleration (+8.8%, small ES), and eccentric force (+26.7, large ES) were substantially higher with VP than with FW. Blood lactate concentration was also greater after the VP exercise (end +32.9%, 3 min later +36%, 5 min later +33.8%; large ES). Maximal concentric force was substantially higher with FW than VP during the 6th set (+6.4%, small ES). In the cohort and exercise investigated in the current study, VP training can be considered an efficient training device to induce an accentuated eccentric overload and augmented metabolic demands (ie, blood lactate concentration).


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