scholarly journals Effect of dietary methionine on chlorobenzene-induced variation in hepatic glutathione and lipid peroxide levels in rats.

1985 ◽  
Vol 38 (4) ◽  
pp. 279-283
Author(s):  
Munehiro YOSHIDA ◽  
Ichiro HARA
Keyword(s):  
Lipid Peroxide ◽  
Hepatic Glutathione ◽  
Induced Variation

Hypolipidemic and antioxidant effects of curcumin and capsaicin in high-fat-fed rats

2007 ◽  
Vol 85 (6) ◽  
pp. 588-596 ◽  
Author(s):  
H. Manjunatha ◽  
K. Srinivasan
Keyword(s):  
Ascorbic Acid ◽  
Glutathione Peroxidase ◽  
Total Cholesterol ◽  
Glutathione Transferase ◽  
Lipid Peroxide ◽  
Tocopherol Content ◽  
High Fat ◽  
Hepatic Glutathione ◽  
Thiol Content ◽  
Antioxidant Effects

The beneficial hypolipidemic and antioxidant influences of the dietary spice compounds curcumin and capsaicin were evaluated. Curcumin, capsaicin, or their combination were included in the diet of high-(30%)-fat-fed rats for 8 weeks. Dietary high-fat-induced hypertriglyceridemia was countered by dietary curcumin, capsaicin, or their combination by 12%–20%. Curcumin, capsaicin, and their combination also produced a slight decrease in serum total cholesterol in these animals. Serum α-tocopherol content was increased by dietary curcumin, capsaicin, and their combination in high-fat-fed rats. Serum total thiol content in high-fat-fed animals and serum ascorbic acid in normal animals was elevated by the combination of curcumin and capsaicin. Hepatic glutathione was increased by curcumin, capsaicin, or their combination in normal animals. Hepatic glutathione and α-tocopherol were increased, whereas lipid peroxide level was reduced by dietary curcumin and combination of curcumin and capsaicin in high-fat-fed animals. Serum glutathione peroxidase and glutathione transferase in high-fat-fed rats were generally higher as a result of dietary curcumin, capsaicin, and the combination of curcumin and capsaicin. Hepatic glutathione reductase and glutathione peroxidase were significantly elevated by dietary spice principles in high-fat-fed animals. The additive effect of the 2 bioactive compounds was generally not evident with respect to hypolipidemic or antioxidant potential. However, the effectiveness of the combination was higher in a few instances.

Effects of Vitamin E Administration on Platelet Function and Serum Lipid Peroxides in DOCA-Salt Hypertensive Rats

1991 ◽  
Vol 65 (04) ◽  
pp. 411-414 ◽  
Author(s):  
Keizo Umegaki ◽  
Hiromi Saegusa ◽  
Masato Kurokawa ◽  
Tomio Ichikawa
Keyword(s):  
Vitamin E ◽  
Platelet Function ◽  
Serum Lipid ◽  
Lipid Peroxide ◽  
Lipid Peroxides ◽  
Hypertensive Rats ◽  
Serotonin Content ◽  
Serum Lipid Peroxide ◽  
Salt Hypertension

SummaryEffects of vitamin E on platelet function and serum lipid peroxide levels were investigated in DOCA-salt hypertensive rats. In the hypertensive rats, ADP- and collagen-induced platelet aggregation in whole blood were markedly attenuated and accompanied by a reduction of serotonin content as compared with the normotensive controls. These facts indicated the appearance of exhausted platelets, which have already been activated in vivo, due to the hypertension. Platelet vitamin E levels were decreased by 50%, while serum lipid peroxide levels were increased 3.6-fold in the hypertensive rats. Vitamin E administration (10 times the dietary intake) during the experimental periods did not influence either the aggregability or the serotonin content of platelets from the hypertensive rats. However, vitamin E administration significantly prevented the elevation of serum tipid peroxides due to the hypertension. These results suggest that vitamin E administration has little effect on platelet activation in vivo due to DOCA-salt hypertension.

Cytogenotoxicity and Lipid Peroxide Induction in Actinomycin D Post-treated Mice

2011 ◽  
Vol 3 (3) ◽  
pp. 15-16
Author(s):  
Ratnakar Parida ◽  
◽  
Ramesh C Choudhury
Keyword(s):  
Actinomycin D ◽  
Lipid Peroxide

Bergenin Exhibits Hepatoprotective Activity Against Ethanol-Induced Oxidative Stress in ICR Mice

2019 ◽  
Vol 18 (4) ◽  
pp. 297-302
Author(s):  
Sriset Yollada ◽  
Chatuphonprasert Waranya ◽  
Jarukamjorn Kanokwan
Keyword(s):  
Reactive Oxygen Species ◽  
Gallic Acid ◽  
Aspartate Aminotransferase ◽  
Alanine Aminotransferase ◽  
Hepatic Injury ◽  
Reduced Glutathione ◽  
Reactive Oxygen ◽  
Hepatoprotective Activity ◽  
Oxygen Species ◽  
Hepatic Glutathione

Bergenin is a C-glucoside derivative of gallic acid but its antioxidant and hepatoprotective effects have not previously been compared with gallic acid. Male ICR mice were administered bergenin (10, 50, and 250 mg/kg/day) or gallic acid (100 mg/kg/day) for 7 consecutive days before a single administration of ethanol (5 g/kg). Liver sections were histopathologically examined. Aspartate aminotransferase, alanine aminotransferase, reactive oxygen species, and malondialdehyde levels were determined in plasma. Total glutathione, reduced glutathione, and oxidized glutathione levels were determined in liver homogenates. Ethanol induced hepatic injury with prominent histopathological markers including nuclear pyknosis and necrotic areas and this accorded with increases in the plasma levels of aspartate aminotransferase, alanine aminotransferase, reactive oxygen species, and malondialdehyde. Moreover, ethanol disturbed hepatic glutathione homeostasis by reducing glutathione stores. Hepatic injury in the ethanol-induced mice was prevented with bergenin and gallic acid by significant decreases in plasma aspartate aminotransferase, alanine aminotransferase, reactive oxygen species, and malondialdehyde levels and restoration of the hepatic glutathione profile through an increase in the reduced glutathione/oxidized glutathione ratio. Bergenin at 10 mg/kg/day showed comparable hepatoprotective activity to gallic acid in an ethanol-induced mouse model of oxidative stress. Therefore, bergenin might be a promising candidate for further development as a novel hepatoprotective product.

Photo-induced variation of magnetism in coordination polymers with ligand-based electron transfer

2021 ◽  
Author(s):  
Yan-Lei Lu ◽  
Wen-Long Lan ◽  
Wei Shi ◽  
Qionghua Jin ◽  
Peng Cheng
Keyword(s):  
Electron Transfer ◽  
Coordination Polymers ◽  
Optical Memory ◽  
High Density ◽  
Information Storage ◽  
Memory Devices ◽  
Storage Materials ◽  
Potential Applications ◽  
Induced Variation

Photo-induced variation of magnetism from ligand-based electron transfer have been extensively studied because of their potential applications in magneto-optical memory devices, light-responsive switches, and high-density information storage materials. In this...

scholarly journals Morpho-Physio-Biochemical Attributes of Roadside Trees as Potential Tools for Biomonitoring of Air Quality and Environmental Health in Urban Areas

Land ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 236
Author(s):  
Ha Na You ◽  
Myeong Ja Kwak ◽  
Sun Mi Je ◽  
Jong Kyu Lee ◽  
Yea Ji Lim ◽  
...  
Keyword(s):  
Air Pollution ◽  
Air Quality ◽  
Environmental Health ◽  
Urban Areas ◽  
Biochemical Parameters ◽  
Lipid Peroxide ◽  
Platanus Occidentalis ◽  
Physiological Variables ◽  
Sources Of Pollution ◽  
Species Specific

Environmental pollution is an important issue in metropolitan areas, and roadside trees are directly affected by various sources of pollution to which they exhibit numerous responses. The aim of the present study was to identify morpho-physio-biochemical attributes of maidenhair tree (Ginkgo biloba L.) and American sycamore (Platanus occidentalis L.) growing under two different air quality conditions (roadside with high air pollution, RH and roadside with low air pollution, RL) and to assess the possibility of using their physiological and biochemical parameters as biomonitoring tools in urban areas. The results showed that the photosynthetic rate, photosynthetic nitrogen-use efficiencies, and photochromic contents were generally low in RH in both G. biloba and P. occidentalis. However, water-use efficiency and leaf temperature showed high values in RH trees. Among biochemical parameters, in G. biloba, the lipid peroxide content was higher in RH than in RL trees, but in P. occidentalis, this content was lower in RH than in RL trees. In both species, physiological activities were low in trees planted in areas with high levels of air pollution, whereas their biochemical and morphological variables showed different responses to air pollution. Thus, we concluded that it is possible to determine species-specific physiological variables affected by regional differences of air pollution in urban areas, and these findings may be helpful for monitoring air quality and environmental health using trees.

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