An extensive involvement: the Treasury Portfolio and the OECD

2017 ◽  
pp. 188-212
Keyword(s):  
Extensive Involvement

Top-Ten Tips for Imaging the Brachial Plexus with Ultrasound and MRI

2019 ◽  
Vol 23 (04) ◽  
pp. 405-418 ◽  
Author(s):  
James F. Griffith ◽  
Radhesh Krishna Lalam
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Brachial Plexus ◽  
Muscle Denervation ◽  
Resonance Imaging ◽  
Neural Injury ◽  
Clinical Indications ◽  
Magnetic Resonance Imaging Mri ◽  
High Level ◽  
Extensive Involvement

AbstractWhen it comes to examining the brachial plexus, ultrasound (US) and magnetic resonance imaging (MRI) are complementary investigations. US is well placed for screening most extraforaminal pathologies, whereas MRI is more sensitive and accurate for specific clinical indications. For example, MRI is probably the preferred technique for assessment of trauma because it enables a thorough evaluation of both the intraspinal and extraspinal elements, although US can depict extraforaminal neural injury with a high level of accuracy. Conversely, US is probably the preferred technique for examination of neurologic amyotrophy because a more extensive involvement beyond the brachial plexus is the norm, although MRI is more sensitive than US for evaluating muscle denervation associated with this entity. With this synergy in mind, this review highlights the tips for examining the brachial plexus with US and MRI.

Lactotransferrin-Related Breast Amyloidosis: Report of a First Case

2021 ◽  
pp. 106689692110160
Author(s):  
Mingfei Yan ◽  
Mark Rodgers ◽  
Aparna Harbhajanka ◽  
Hannah Gilmore
Keyword(s):  
Breast Lesion ◽  
Hematologic Malignancy ◽  
Genetic Disorders ◽  
Rare Condition ◽  
Myoepithelial Cells ◽  
Hematological Disorders ◽  
First Case ◽  
Benign Nature ◽  
Extensive Involvement

Breast amyloidosis is a rare condition which is mostly associated with hematological disorders or hereditary genetic disorders. Imaging findings of breast amyloidosis can mimic malignancy, which often leads to biopsy or excision of the lesion. Here, we presented a case of localized lactotransferrin-related breast amyloidosis in an elderly female patient. Histologic examination revealed extensive involvement of breast lobules by amorphous amyloid materials, with attenuation of lobular structures and prominent calcifications. Positive immunostains for myoepithelial cells helped to exclude the possibility of invasive carcinoma. The patient had no hematologic malignancy besides immunoglobulin G lambda monoclonal gammopathy of undetermined significance. Mass spectrometry of the breast amyloid identified lactotransferrin and no immunoglobulin or its light chain. On follow-up, the patient showed no recurrence of the breast lesion after local excision nor showed other systematic comorbidities, indicating the benign nature of the lesion. This first report of lactotransferrin-related amyloidosis may represent a special type of localized breast amyloidosis that has no correlation with systematic disorders.

Management of regional enteritis

1966 ◽  
Vol 4 (23) ◽  
pp. 90-91
Keyword(s):  
Weight Loss ◽  
Small Bowel ◽  
Chronic Inflammation ◽  
Regional Enteritis ◽  
Skin Lesions ◽  
Blind Loop Syndrome ◽  
Electrolyte Disturbance ◽  
Extensive Involvement ◽  
Acute Ileitis ◽  
Disturbance Growth

Regional enteritis (Crohn’s disease) is an uncommon chronic inflammation of unknown cause involving one or more parts of the gut.1–3 The affected parts are often thickened: the mucosa is usually ulcerated and there may be adhesions and fistulae. This can cause diarrhoea, steatorrhoea, pain, and acute and chronic obstruction. Malabsorption occurs in extensive involvement of the small bowel or in the ‘blind loop’ syndrome due to strictures, fistulae or by-pass operations, and in addition protein may be lost in the bowel. The fistulae may occur between loops of bowel, and anal fistulae are common. These disorders can cause malaise, fever, anaemia, weight loss, hypoproteinaemia and electrolyte disturbance. Growth may be arrested. Skin lesions, arthropathy and iritis may develop. The first attack may occur at any age, and the disease usually runs a chronic and unpredictable course. However, acute ileitis, diagnosed surgically, does not usually recur,4–6 and it may be a different condition.6

Fulminant Multisystem Non–Langerhans Cell Histiocytic Proliferation With Hemophagocytosis

2005 ◽  
Vol 129 (2) ◽  
pp. e39-e43 ◽  
Author(s):  
R. Nagarjun Rao ◽  
Chung-che Chang ◽  
Nevin Uysal ◽  
Kenneth Presberg ◽  
Vinod B. Shidham ◽  
...  
Keyword(s):  
Langerhans Cell Histiocytosis ◽  
Clinical Course ◽  
Langerhans Cell ◽  
Variant Form ◽  
Malignant Histiocytosis ◽  
Unique Case ◽  
Multiple Organs ◽  
Biopsy Specimens ◽  
Extensive Involvement ◽  
Erdheim Chester

Abstract Hemophagocytosis (HP), a feature seen in malignant histiocytosis and infection- and lymphoma-associated disorders, has not been previously emphasized in Erdheim-Chester disease (ECD). Generally, ECD is recognized as a rare, systemic, non–Langerhans cell histiocytosis with a variable clinical course. Herein, we describe a unique case of multisystem non–Langerhans cell histiocytic proliferation with a fulminant clinical course (death occurred within 3 months of presentation) that showed prominent HP and extensive involvement of multiple organs, including the lungs, resulting in respiratory failure. Hemophagocytosis led to severe anemia that required transfusion and thrombocytopenia. Antemortem lung and bone marrow biopsy specimens revealed involvement by a histiocytic infiltrate with features highly suggestive of ECD and HP. Furthermore, the autopsy documented the presence of HP and the histiocytic infiltrate in multiple other organs. This case is best categorized as a variant form of ECD. Recognizing this variant has the following important implications: (1) HP may be a marker for fulminant clinical course in ECD, (2) the presence of HP does not exclude a diagnosis of ECD, and (3) ECD should be considered in the differential diagnosis of HP.

scholarly journals Kearns-Sayre syndrome with facial and white matter extensive involvement: a (mitochondrial and nuclear gene related?) neurocristopathy?

2017 ◽  
Author(s):  
Agostino Berio ◽  
Attilia Piazzi ◽  
Carlo Enrico Traverso
Keyword(s):  
Nervous System ◽  
White Matter ◽  
Neural Crest Cell ◽  
Nuclear Gene ◽  
Mtdna Mutations ◽  
Kearns Sayre Syndrome ◽  
Mtdna Deletion ◽  
The Common ◽  
Crest Cell ◽  
Extensive Involvement

The Authors report on a patient with Kearns-Sayre syndrome, large mtDNA deletion (7/kb), facial abnormalities and severe central nervous system (CNS) white matter radiological features, commonly attributed to spongy alterations. The common origin from neural crest cell (NCC) of facial structures (cartilagineous, osseous, vascular and of the peripheral nervous system) and of peripheral glia and partially of the CNS white matter are underlined and the facial and glial abnormalities are attributed to the abnormal reproduction/migration of NCC. In this view, the CNS spongy alterations in KSS may be not only a dystrophic process (leukodystrophy) but also a dysplastic condition (leukodysplasia). The Authors hypothesize that the symptoms may be related to mtDNA mutations associated to NCC nuclear gene abnormality. SOX 10 gene may be a nuclear candidate gene, as reported in some case of Waardenburg IV syndrome.

Multi-organ hydatidosis with extensive involvement of the hemi-pelvis and ipsilateral femur

2013 ◽  
Vol 62 (1) ◽  
pp. 82-85 ◽  
Author(s):  
Sudhir K. Kapoor ◽  
Himanshu Kataria ◽  
Satya Ranjan Patra ◽  
Meenakshi Bharadwaj ◽  
Vipul Vijay ◽  
...  
Keyword(s):  
Extensive Involvement

scholarly journals Recycling pathways of glucosylceramide in BHK cells: distinct involvement of early and late endosomes

1992 ◽  
Vol 103 (4) ◽  
pp. 1139-1152
Author(s):  
J.W. Kok ◽  
K. Hoekstra ◽  
S. Eskelinen ◽  
D. Hoekstra
Keyword(s):  
Plasma Membrane ◽  
Intracellular Ph ◽  
Brefeldin A ◽  
Fluid Phase ◽  
Endocytic Pathway ◽  
Late Endosomes ◽  
Early Endosomes ◽  
Recycling Pathway ◽  
Golgi Network ◽  
Extensive Involvement

Recycling pathways of the sphingolipid glucosylceramide were studied by employing a fluorescent analog of glucosylceramide, 6(-)[N-(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoylglucosyl sphingosine (C6-NBD-glucosylceramide). Direct recycling of the glycolipid from early endosomes to the plasma membrane occurs, as could be shown after treating the cells with the microtubule-disrupting agent nocodazole, which causes inhibition of the glycolipid's trafficking from peripheral early endosomes to centrally located late endosomes. When the microtubuli are intact, at least part of the glucosylceramide is transported from early to late endosomes together with ricin. Interestingly, also N-(lissamine rhodamine B sulfonyl)phosphatidylethanolamine (N-Rh-PE), a membrane marker of the fluid-phase endocytic pathway, is transported to this endosomal compartment. However, in contrast to both ricin and N-Rh-PE, the glucosylceramide can escape from this organelle and recycle to the plasma membrane. Monensin and brefeldin A have little effect on this recycling pathway, which would exclude extensive involvement of early Golgi compartments in recycling. Hence, the small fraction of the glycolipid that colocalizes with transferrin (Tf) in the Golgi area might directly recycle via the trans-Golgi network. When the intracellular pH was lowered to 5.5, recycling was drastically reduced, in accordance with the impeding effect of low intracellular pH on vesicular transport during endocytosis and in the biosynthetic pathway. Our results thus demonstrate the existence of at least two recycling pathways for glucosylceramide and indicate the relevance of early endosomes in recycling of both proteins and lipids.

scholarly journals The Evolution of China’s Sporting Diplomacy since 1949

2021 ◽  
Vol 45 (3) ◽  
pp. 271-283
Author(s):  
Yalun An ◽  
Xueshuang Wang ◽  
Fujun Xiang
Keyword(s):  
Soft Power ◽  
Sports Events ◽  
Chinese Characteristics ◽  
Emerging Issues ◽  
Practical Experiences ◽  
Peaceful Development ◽  
Mega Sports Events ◽  
Decision Environments ◽  
Extensive Involvement ◽  
China’S Economy

The sporting diplomacy in China, as an integral part of China’s overall diplomacy, unswervingly upholds the fundamental foreign policy goal of preserving world peace and promoting common development since New China was founded. After adopting the policy of reform and opening, the sporting diplomacy in China has made historical achievements through intensive participation in international sporting competitions, extensive involvement in international sporting organizations, active hosting of mega sports events, and frequent engagement in cultural sporting exchanges with other countries. In the last decade, with a constant increase in China’s economy, cultural soft power and international influence of sports, China makes an all-round effort in the pursuit of major countrywide sporting diplomacy with Chinese characteristics. Currently, despite the severe challenges outside China, Beijing is making smooth preparations for the 2022 Winter Olympic and Paralympic Games, which embraces another milestone in the diplomacy of sport in China. This paper analyzes decision environments, goals, actions and defining features of China’s sporting diplomacy in different periods and follows on to summarize practical experiences in the development of the sporting diplomacy in China. The paper shows that the resounding success of China’s sporting diplomacy can be attributed to its commitment to serving the country’s diplomatic strategy and core interests, its commitment to following the Chinese path of sporting diplomacy, and its commitment to the traditional Chinese value of peaceful development. Finally, emerging issues and promotion strategies are presented.

scholarly journals Extensive Primary Anetoderma Refractory to Erbium YAG Fractionally Ablative Laser

2020 ◽  
Vol 4 (3) ◽  
pp. 284
Author(s):  
James C Prezzano ◽  
Christopher T Richardson ◽  
Glynis A Scott ◽  
Sherrif F Ibrahim
Keyword(s):  
Laser Treatment ◽  
Surface Area ◽  
Body Surface ◽  
Normal Skin ◽  
Small Body ◽  
Elastic Fibers ◽  
Clinically Normal ◽  
Psychosocial Difficulties ◽  
Extensive Involvement ◽  
Ablative Laser

Primary anetoderma is a rare elastolytic disorder characterized by well-circumscribed flaccid, atrophic macules and patches caused by focal loss of elastic fibers. Anetoderma is divided into two forms: primary, which is idiopathic and occurs on clinically normal skin, and secondary, which follows a prior dermatosis. Although it is indolent, the lesions of anetoderma persist and may be associated with significant aesthetic changes causing potential psychosocial difficulties. Anetoderma has been successfully treated with ablative, pulsed dye and non-ablative fractionated lasers. Patients with secondary anetoderma and anetoderma limited to a relatively small body surface area may be more amenable to laser treatment than patients with extensive involvement.

scholarly journals The Transformation of Greek Orthodox Ecclesiastical Institutions in Cyprus, 1878-1931

Chronos ◽  
2019 ◽  
Vol 22 ◽  
pp. 7-23 ◽  
Author(s):  
Victor Roudometof
Keyword(s):  
Political Agenda ◽  
Greek Orthodox ◽  
British Rule ◽  
Greek Cypriot ◽  
National Sentiment ◽  
The Face ◽  
The One ◽  
Elected Representatives ◽  
The Church ◽  
Extensive Involvement

In this discussion, I outline the transformation of Greek Orthodox identity in Cyprus during the first 50 years of British rule over the island. The year 1931 marks the first Greek Cypriot anti-colonial revolt (Oktomvriana), and the post-1931 period constitutes the period in which the Greek Cypriot goal of union (enosis) with Greece is forcefully put forth in the political agenda. In the article's opening section, I outline the main institutional and political changes of the post-1878 period. In this era, ecclesiastical institutions underwent a major internal transformation as the religious hierarchy reasserted its authority in the face of new and threatening legislation enacted by the British. In pursuing this goal the church hierarchs became increasingly involved in the politics of Greek Cypriot nationalism. This involvement was expressed in a twofold manner: on the one hand, the hierarchs succeeded in legitimizing themselves as elected representatives of the Greek Cypriot community in the colonial administrative and legislative structures; while on the other hand, the church's extensive involvement in education allowed it to identify its own authority with the defense and propagation of pro-Greek national sentiment.

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