Histopathological Review and Distribution of Granulomatous Inflammatory Disorders in Makurdi, North Central Nigeria

2021 ◽  
Vol 2 (2) ◽  
pp. 1-6
Author(s):  
JA Ngbea ◽  
MN Agwa ◽  
DT Gyenger ◽  
T Nyaga ◽  
OI Akpor ◽  
...  
Keyword(s):  
Plasma Cells ◽  
Granulomatous Inflammation ◽  
University Teaching ◽  
State University ◽  
Cervical Lymph Nodes ◽  
North Central ◽  
Inflammatory Disorders ◽  
Special Stain ◽  
Tissue Site ◽  
Anatomical Pathology

Granulomatous inflammation is a pattern of chronic inflammation characterized by the presence of granulomas consisting of microscopic aggregates of macrophages transformed into epithelioid cells surrounding by a collar of lymphocytes and occasioned plasma cells. The study aimed to determine the distribution by tissue site, histological patterns of granulomatous inflammatory disorders in Benue State University Teaching Hospital (BSUTH), Makurdi over a 5-year period. This was a 5 year (March 2013 – February 2018) retrospective study of all cases diagnosed as granulomatous inflammatory disorders on Haematoxylin and Eosin-stained sections at the Anatomical pathology Department. Ziehl-Neelsen special stain was also done on all specimens. A total of two hundred and thirty-six (236) cases of granulomatous inflammatory disorders were diagnosed, analysed and categorized based on the tissue site, on Haematoxylin and Eosin-stained sections; Ziehl-Neelsen special stain was done on all cases. The most common sites were cervical lymph nodes, appendix, skin, testicular tissues etc with the Eyelid been the least common site.

scholarly journals Auditing Appendectomy in Benue State University Teaching Hospital, Makurdi, Nigeria.

2019 ◽  
Vol 6 (4) ◽  
pp. 123-125
Author(s):  
Barnabas Eke ◽  
Babarinde Ojo ◽  
Bamidele Omolobake ◽  
Umobong Emanso ◽  
Issac Akpor ◽  
...  
Keyword(s):  
Teaching Hospital ◽  
Granulomatous Inflammation ◽  
University Teaching ◽  
Total Leukocyte Count ◽  
Negative Appendectomy ◽  
State University ◽  
Surgical Specimen ◽  
Reactive Protein ◽  
Resource Center ◽  
Negative Appendectomy Rate

Appendicitis is the leading cause of surgical admission in most hospitals in Nigeria and the removed appendix, a frequent surgical specimen in most routine histopathological laboratories in Nigeria. The aim of this study is to audit the appendectomy procedures in Benue State University Teaching Hospital. Sixty-two appendices removed for acute appendix in Benue State University Teaching Hospital, Makurdi, Nigeria middle belt, over an 8-year period were analyzed. Twenty-eight (45%) were found to be normal, while 29 (46%) showed histopathological evidence of acute inflammation. There were 5 (9%) cases of unusual pathologies which include a case each of metastatic adenocarcinoma and chronic granulomatous inflammation (2% each) and 3 (5%) cases of schistosomiasis. The Negative Appendectomy Rate (NAR) was 27% in females compared with 18% in males. Adult (>16 years) represented 29% of the NAR. The overall NAR was 45%. The NAR in this study is considerable higher when compared with existing literature. In a poor resource center like Benue State University Teaching Hospital, due diligence in taking detailed history coupled with good clinical examination cannot be over emphasized. The use of a combination of Total Leukocyte Count (TCC) and C-Reactive Protein (CPR) in every patient may help in reducing NAR, though it’s definitely going to be impossible to eradicate it.

Clinico-pathological characteristics of Skin Cancers at Benue State University Teaching Hospital, Makurdi, North Central Nigeria

2016 ◽  
Vol 12 (2) ◽  
pp. 56 ◽  
Author(s):  
ChukwukadibiaN Ahachi ◽  
PriscillaDenen Akaa ◽  
ItodoC Elachi ◽  
DanielD Mue ◽  
JosephA Ngbea ◽  
...  
Keyword(s):  
Teaching Hospital ◽  
University Teaching ◽  
State University ◽  
North Central ◽  
Pathological Characteristics ◽  
Skin Cancers

scholarly journals Cord Blood Haematological Profiling Study: Predictive Markers of Neonatal Health Status at Birth in Anyigba, North Central Nigeria

2021 ◽  
pp. 33-39
Author(s):  
Shedrack Egbunu Akor ◽  
Dickson Achimugu Musa ◽  
S. P. O. Akogu ◽  
Akpa Matthew ◽  
Adeyemi Alapo Funmilola ◽  
...  
Keyword(s):  
Health Status ◽  
Cord Blood ◽  
Neonatal Mortality ◽  
Umbilical Cord ◽  
Teaching Hospital ◽  
Umbilical Cord Blood ◽  
University Teaching ◽  
Haematological Parameters ◽  
State University ◽  
North Central

Background: Neonatal mortality refers to the death of a live-born babies within the first 28 days of life remains a global public health challenge. Cord blood being the medium of communication, transmission of nutrients and wastes between mothers and fetus can reflect the health status of baby at birth if properly utilized. Owing to multiple factors involved in neonatal mortality, this study used umbilical cord blood haematological parameters to ascertain the health status of neonates at birth, the aim of this study is to use umbilical cord blood haematological parameters for management of neonates at birth. Methodology: This research is a cross-sectional study carried out at the Departments of Obstetrics and Gynaecology and Medical Laboratory Department, Kogi State University Teaching Hospital, Anyigba, North Central Nigeria between January, and December, 2020.  Cord blood from 164 babies delivered in Kogi State University Teaching Hospital, Grimard Catholic Hospital, and Amazing Grace Hospital between January and December, 2020 were analyzed for haematological parameters using Sysmex XP-300 automated haematology analyzer. The data obtained were expressed as mean ±standard deviation using SPSS statistical software, version 23.0. The indicator level of statistical significance was set at p<0.05. Results: The results showed significant increase (p<0.05) of WBC, RBC, MCV, MCH and MCHC in unstable babies compared to the stable babies, significant decrease (p<0.05) in the platelets, neutrophil and mixed among unstable babies compared to the stable babies, but no significant difference in PCV,  haemoglobin and lymphocyte counts of both stable and unstable babies. The results also demonstrated 25 deaths per 1000 live newborn neonates within 48hour during the period of study. Conclusion: This study shows that cord blood haematological parameters at birth can be used to ascertain the health status of neonates.

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