scholarly journals A Cross-Sectional Study to Determine the Prevalence of Gastroesophageal Reflux in Children with Persistent Cough and Wheezing

2020 ◽  
Vol 8 (4) ◽  
pp. 36-40
Author(s):  
Praveen P N ◽  
Kushvanth K N ◽  
Ashish Mallige

Background: Gastroesophageal reflux (GER) occurs in more than two-thirds of otherwise healthy infants and is the topic of discussion with pediatricians at one-quarter of all routine 6-month infant visits. GER is considered a normal physiologic process that occurs several times a day in healthy infants, children, and adults. GER is generally associated with transient relaxations of the lower esophageal sphincter independent  of swallowing, which permits gastric contents to enter the esophagus. The Objective to find out the prevalence of GER in children with cough and wheezing and its associated factors. Subjects and Methods: A cross-sectional study was done at A tertiary care hospital at the Institute of Naval Medicine, INHS, Mumbai from August 2016 to December 2017. A total of 30 study subjects Aged between the age of one to twelve years with persistent cough and wheezing lasting for more than three months despite treatment were included for the study. Results: The prevalence of gastroesophageal reflux (GER) in our study was 63.3%.The logistic regression analysis showed that Age, Height, Weight, BMI, duration of cough, Duration of asthma were not significantly associated with Gastroesophageal reflux (GER) (p>0.05). Conclusion: GER seems to have a high prevalence in children with chronic cough. However, no definite recommendations can be made regarding the management of such cases from our study.

2021 ◽  
Vol 11 (2) ◽  
pp. 102-106
Author(s):  
Akhtar Ali Khan ◽  
Anwar Ali ◽  
Hussan Zeb ◽  
Bakht Rahman ◽  
Ijaz Arif ◽  
...  

Background: This research aimed to assess the current care management processes for COVID-19 and determine patient outcomes. Methods: An analytical cross-sectional study was conducted at Saidu group of teaching hospital, a tertiary care hospital with more than a thousand-bed capacity. The target population was all patients admitted to the corona isolation ward and the hospital's critical unit. All the patients admitted through the emergency and inpatient department with Positive PCR, and respiratory symptoms were included in the study. Results: In total, data of 151 patients were collected. Of these, 90 (59.6%) were male and 61 (40.4%) were female with a mean age of 59.17±13.79. The most common presenting symptoms were difficulty in breathing (n=147, 97.4%) and dry cough (n=104, 68.9%), followed by aches and pain (n=71, 47%) and fever (n=60, 39.7%). Most of the patients had an underlying health condition (n=96, 63.6%). The most common underlying conditions were hypertension (n=65, 43%) and diabetes (n=56, 37.1%). The mean time for the hospital stay was 11.68±15.31. About 64% of the patients recovered with the treatment and care protocols (n=97, 64.2%), while the remaining (n=54, 35.8%) died. Conclusion: This study provides an overview of the clinical presentation and treatment protocol for COVID-19. Most of the patients received supportive treatment comprising of antivirals, steroids, and oxygen therapy. However, the mortality rate was low compared to other hospitals across the country.


2019 ◽  
Vol 6 (4) ◽  
pp. 1153
Author(s):  
Anshuman . ◽  
S. R. Kulkarni

Background: Gastroesophageal reflux disease (GERD) is one of the main gastrointestinal diseases. It is due to the abnormal reflux of gastric contents into the esophagus or beyond. It has many symptoms and also many complications.Methods: Authors carried out this study to know the common symptoms, complications of GERD and the endoscopic study results regarding the same. 100 patients attending the surgery department at a tertiary care hospital were included in the study.Results: Mean age of participants was 54.09±14.75 years. Authors divided the 100 patients into two groups, GERD with complications (28 patients) and GERD without complications (72 patients). In the present study, out of 100 GERD patients, 73 patients were males (73%) and 27 patients were females (27%) with male to female ratio of 2.7:1. In this study, among 100 GERD patients, body mass index was <25 in 70 patients (70%) and ≥25 in 30 patients (30%). Heartburn was present in 72% patients, regurgitation in 71%, retrosternal chest pain was seen in 68% patients and dysphagia was seen in 29%. Out of 100 GERD patients, 16 patients (16%) had esophageal ulcers, 8 patients (8%) had Barrett’s esophagus, 4 patients (4%) had esophageal stricture and 72 patients (72%) didn’t have any complications.Conclusions: Age and BMI (both p <0.001) of the patients showed significant statistical difference between two groups. Some other studies also showed similar results with higher complications seen in increasing age and increased frequency of symptoms.


Vacunas ◽  
2020 ◽  
Vol 21 (2) ◽  
pp. 95-104 ◽  
Author(s):  
Y.M. AlGoraini ◽  
N.N. AlDujayn ◽  
M.A. AlRasheed ◽  
Y.E. Bashawri ◽  
S.S. Alsubaie ◽  
...  

Author(s):  
Nandini Chatterjee ◽  
Supratick Chakraborty ◽  
Mainak Mukhopadhyay ◽  
Sinjon Ghosh ◽  
Bikramjit Barkandaj ◽  
...  

2020 ◽  
Vol 32 (1) ◽  
Author(s):  
Nearmeen M. Rashad ◽  
Marwa G. Amer ◽  
Waleed M. Reda Ashour ◽  
Hassan M. Hassanin

Abstract Background Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system with varied clinical features. Disease-modifying drugs (DMDs) of MS associated with different types of thyroiditis. In this cross-sectional study, we aimed to assess the prevalence of thyroid dysfunction in MS and to investigate the association between DMDs and the risk of thyroiditis in MS. A cross-sectional study included 100 patients with relapsing-remitting multiple sclerosis (RRMS) in relapse, and the diagnosed was according to revised McDonald’s criteria 2010. Results Our results revealed that the prevalence of thyroiditis was 40%; autoimmune (34%) and infective (6%) among patients with RRMS in relapse and cerebellar symptoms were significantly higher in patients with thyroiditis compared to patients without thyroiditis. Regarding the association between DMDs and thyroiditis, the prevalence of patients treated with interferon-beta-1b was higher in MS patients with thyroiditis compared to MS patients without thyroiditis. However, the prevalence of patients treated with interferon-beta-1a was lower in MS patients with thyroiditis compared to MS patients without thyroiditis. In addition, we found CMV infection was more common in patients treated by interferon beta-1b and candida infection was common in patients treated by fingolimod. Conclusions Thyroiditis is commonly observed in patients with RRMS in relapse and higher prevalence of patients treated with interferon-beta-1b which is commonly associated with thyroiditis and CMV infection; however, candida thyroid infection was common in MS patients treated by fingolimod.


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