scholarly journals Dynamics of Erythrocyte Sedimentation Rate vs. C – reactive protein: Peas in a Pod or Chalk and Cheese?

2021 ◽  
Vol 04 (02) ◽  
Author(s):  
Arash Eatemadi ◽  
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Acute Phase ◽  
Antimicrobial Stewardship ◽  
Sedimentation Rate ◽  
Hospitalized Patients ◽  
C Reactive Protein ◽  
Acute Phase Reactants ◽  
Reactive Protein ◽  
Erythrocyte Sedimentation

Acute phase reactants have a supplementary role in the management of hospitalized patients with fever. While not perfect tools, they have some role in formulating a diagnostic and therapeutic plan and may improve antimicrobial stewardship. The Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), while not specific enough to establish a diagnosis, can be helpful in guiding the intensity and duration of anti-infective therapy. However, they have different dynamics during inflammations and infections.

scholarly journals Role of erythrocyte sedimentation rate and C-reactive protein as a predictor of severity of cellulitis and necrotising fasciitis

2020 ◽  
Vol 7 (7) ◽  
pp. 2176
Author(s):  
Sanjay Jain ◽  
Manish Kumar ◽  
M. C. Songara
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Mean Value ◽  
Necrotising Fasciitis ◽  
Industrialized Countries ◽  
C Reactive Protein ◽  
Specific Test ◽  
Acute Phase Reactants ◽  
Reactive Protein ◽  
Erythrocyte Sedimentation

Background: Skin infections are major cause of morbidity and mortality worldwide, affecting more than one person/1000 person/year. Sepsis has a worldwide incidence of more than 20 million cases a year, with mortality due to septic shock reaching up to 50% even in industrialized countries. Acute phase reactants like erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) have been used traditionally as markers for inflammation and are readily available in most centres. Aim was to study the correlation between the values of ESR and CRP with severity of cellulitis and necrotising fasciitis (in term of hospital stay and disease outcome).Methods: This was a prospective observational study conducted at Department of Surgery, GMC and Hamidia Hospital, Bhopal from a period of March 2016 to August 2018.Results: Skin and soft tissue infections are most commonly affects male, diabetes mellitus most common co-morbid condition. Mean value of ESR and CRP in patients who could not survived was 64.44 and 145.92 respectively and value more than 54.95 and 93.41 requires longer hospital stay.Conclusions: ESR and CRP are non-specific test but they are good predictors of severity of cellulitis and necrotising fasciitis not only in planning of management of these cases but also predicting outcome of the disease.

scholarly journals Hubungan Antara Kadar Laju Endap Darah (LED) Dengan Kadar C-Reaktiv Protein (CRP) Pada Penderita Tuberkulosis (TBC) Di Wilayah Kerja Puskesmas Alas Barat

2020 ◽  
Vol 7 (1) ◽  
pp. 34
Author(s):  
Aini Aini Aini ◽  
Nurmawan Nurmawan ◽  
Jumari Ustiawaty
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Acute Phase ◽  
Sedimentation Rate ◽  
The Body ◽  
Bacterial Invasion ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Erythrocyte Sedimentation ◽  
Positive Smear ◽  
Smear Negative

Tuberculosis is a disease caused by rod-shaped bacteria (basil) with another name Mycrobacterium tuberculosis. Mycrobacterium tuberculosis enters the body then causes inflammation, inflammation and bacterial invasion which then induces liver cells to synthesize acute phase C-reactive protein protein (CRP). CRP will increase sharply after inflammation, as well as the formation of aggregates derived from the acute phase protein hormone which causes an increase in the Erythrocyte sedimentation rate (ESR)). The purpose of this study was to determine the relationship Erytrocyte sedimentation rate (ESR) and levels of C-Reactiv protein (CRP) in tuberculosis (TBC) patients. This research is an analytical descriptive study using cross sectional. Data collectors are done using the Non Random Accidental Sampling technique. The number of respondents in this study were 11 people with tuberculosis. Based on the results of this study it is known that TBC patients with smear negative as much as 7 people (63.6%) and TB patients with positive smear as much as 4 people (36.4%), both in TB patients with negative smear and positive smear both have levels of ESR not normal with an average ESR level in positive smear of 101.3 mm / hour and the average ESR level in smear negative is 20.8 mm / hour. All TBC patients with smear positive CRP levels (not normal) with an average mean value of CRP of 36 mg / L or an average CRP level in TBC smear negative patients of 0.9 mg / L. Based on the Pearson test results between levels of erythrocyte sedimentation rate (ESR) with C-Reactive protein (CRP) in tuberculosis (TBC) patients obtained a value of p <0.01 (0.000 <0.01). This shows a strong relationship between LED and CRP levels in TB patients

scholarly journals Prognostic Roles of C-Reactive Protein and Erythrocyte Sedimentation Rate As Acute Phase Reactants in Mentally Challenged Subjects

2018 ◽  
Vol 13 (4) ◽  
pp. 311
Author(s):  
Adedeji David Atere ◽  
Bashiru S. A. Oseni ◽  
Ifelola Patience Adebua ◽  
Joshua Seun Fapohunda ◽  
Idomeh Festus Aigbokheo
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Acute Phase ◽  
Sedimentation Rate ◽  
Mental Illnesses ◽  
Psychiatric Disease ◽  
Economic Downturn ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Markers Of Inflammation ◽  
Erythrocyte Sedimentation

Background: A mental disorder is a psychiatric disease that presents as mild or severe disturbances in a person’s behavior, mood, or thought. Mental illnesses are very common because of excessive stress. Recent studies show that mental illnesses are on the rise generally because of increasing stress. In Nigeria, medical records suggest an upsurge in mental health cases since the onset of the country’s economic downturn and the consequent trauma following it. The erythrocyte sedimentation rate (ESR) is an indirect marker of serum acute-phase protein concentrations, whereas C-reactive protein (CRP) is a direct protein measurement and it is inherently more well-defined. This study thus evaluated the roles of ESR and CRP as sensitive markers of inflammation and correlated their levels with severity stratification and prognosis in schizophrenic patients. 

Diagnostic value of procalcitonin, erythrocyte sedimentation rate (ESR), quantitative C-reactive protein (CRP) and clinical findings associated with osteomyelitis in patients with diabetic foot

2021 ◽  
pp. 1-7
Author(s):  
Zahra Soleimani ◽  
Fatemeh Amighi ◽  
Zarichehr Vakili ◽  
Mansooreh Momen-Heravi ◽  
Seyyed Alireza Moravveji
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Roc Curve ◽  
Diabetic Foot ◽  
Diagnostic Value ◽  
Clinical Findings ◽  
Diabetic Patients ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Erythrocyte Sedimentation

BACKGROUND: The diagnosis of osteomyelitis is a key step of diabetic foot management. Procalcitonin (PCT) is a novel infection marker. This study aimed to investigate the diagnostic value of procalcitonin and other conventional infection markers and clinical findings in diagnosis of osteomyelitis in diabetic foot patients. METHODS AND MATERIALS: This diagnostic value study was carried out on ninety patients with diabetic infected foot ulcers admitted in Kashan Beheshti Hospital, 2016. After obtaining consent, 10 cc blood sample was taken for measuring serum PCT, CBC, ESR, CRP and FBS. Clinical characteristics of the wounds were noted. Magnetic resonance imaging of the foot was performed in all patients to diagnose osteomyelitis. All statistical analyses were done with the use of SPSS-16. RESULTS: PCT levels were 0.13 ± 0.02 ng/mili patients with osteomyelitis (n= 45) and 0.04 ± 0.02 ng/ml in patients without osteomyelitis (n= 45). PCT, Erythrocyte sedimentation rate and C-reactive protein was found significantly higher in patients with osteomyelitis (p< 0.001). The ROC curve was calculated for PCT. The area under the ROC curve for infection identification was 1 (p< 0.001). The best cut-off value for PCT was 0.085 ng/ml. Sensitivity, specificity, and positive and negative predictive values were 100%, 97.8%,97.8% and 100%, respectively. CONCLUSION: In this group of patients, PCT was useful to discriminate patients with bone infection. Also, Erythrocyte sedimentation rate and C-reactive protein can be used as a marker of osteomyelitis in diabetic patients.

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