scholarly journals Efficacy of Siddha medicine in the treatment of COVID- 19 patients - A pilot study

2021 ◽  
Vol 12 (3) ◽  
pp. 610-617
Author(s):  
Nikil Niva John Raja ◽  
Ashttalakshmi Anjapuli ◽  
Suganya Poongavanam ◽  
Dineshkumar Sivakumar ◽  
Sasirekha Ranganathan ◽  
...  
Keyword(s):  
Pilot Study ◽  
Disease Transmission ◽  
Care Practice ◽  
Health Care Practice ◽  
Pharmacological Activities ◽  
Health Security ◽  
Reactive Protein ◽  
Alternate Therapy ◽  
New Gateway ◽  
Present Pilot Study

The pandemic triggered by coronavirus disease (COVID-19) invariably questions the health security of people around the globe. It’s also strongly advocates the need for unique health care practice that substantially prevents the infection and practice of controlling the disease transmission. Alternate therapy with viable medications that can adequately strengthen the immune system to enhance the speedy recovery of the patients becomes the need of the hour. Siddha system of medicine is one such versatile practice that emerged before centuries that incorporates the practice of availing potential remedies from herbal and another natural origin. Still, now there is no proper documentary evidence on evaluating the efficacy of Siddha treatment in the clinical management of COVID-19, hence the main objective of the present pilot study is to investigate the potential of Siddha formulations such as Aadathodai kudineer, Thaalisaathi chooranam, Thulasi chooranam, Pavala parpam, Bramaanandha Bairava Maathirai and Thoothuvalai nei in treatment and accelerating the recovery of COVID19 patients. A Study was executed in 25 patients with laboratory- confirmed diagnosis of COVID-19. The Outcome of the present clinical study signifies that treatment with Siddha medicines significantly accelerated recovery of patients by stabilising the immune mechanism which was evidenced by pronouncing declination in CRP (C- reactive protein), neutrophil, lymphocytes, Lactate dehydrogenase (LDH), Creatinine, Serum Albumin and Serum Urea level almost back to the normal. In conclusion therapy with Siddha medicines opened a new gateway in the clinical practice on managing COVID-19 due presence of vital phytotherapeutics that showcase multiple pharmacological activities against risky pathogens like SARS-CoV-2. 

A Measure of Family Functioning for Health Care Practice and Research in Israel

1984 ◽  
Vol 15 (2) ◽  
pp. 211-230 ◽  
Author(s):  
S. Linder-Pelz ◽  
S. Levy ◽  
A. Tamir ◽  
T. Spenser ◽  
L. M. Epstein
Keyword(s):  
Health Care ◽  
Family Functioning ◽  
Care Practice ◽  
Health Care Practice

Ethical Visions for the Development of Patient Care in the Health Care Practice

2019 ◽  
Vol 2 (1) ◽  
pp. 27-34
Author(s):  
Richard Moreno ◽  
◽  
Cristinel Ștefănescu ◽  
Beatrice Gabriela Ioan ◽  
Mariana Cuceu ◽  
...  
Keyword(s):  
Health Care ◽  
Patient Care ◽  
Care Practice ◽  
Health Care Practice

scholarly journals The Efficacy of Convalescent Plasma Use in Critically Ill COVID-19 Patients

Medicina ◽  
2021 ◽  
Vol 57 (3) ◽  
pp. 257
Author(s):  
Livius Tirnea ◽  
Felix Bratosin ◽  
Iulia Vidican ◽  
Bianca Cerbu ◽  
Mirela Turaiche ◽  
...  
Keyword(s):  
Pilot Study ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Therapeutic Option ◽  
White Blood Cells ◽  
The United States ◽  
Plasma Therapy ◽  
Reactive Protein ◽  
United States Food ◽  
States Food

Background and Objectives: On 24 March 2020, the United States Food and Drug Administration (FDA) announced the approval of convalescent plasma therapy for critically ill patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as an emergency investigational new drug. This pilot study from Romania aimed to determine if convalescent plasma transfusion can be beneficial in the treatment of selected critically ill patients diagnosed with a SARS-CoV-2 infection. Materials and Methods: Donor and receiver eligibility for critically ill coronavirus disease 2019 (COVID-19) patients was based on Romanian guidelines issued at the time of the study. Here, we describe the evolution of a total of five eligible patients diagnosed with COVID-19 who received convalescent plasma (CP) in Romania. Results: In spite of our efforts and convalescent plasma administration, three of the five patients did not survive, while the other two recovered completely. Over the course of our five-day laboratory record, the surviving patients had significantly lower values for C-reactive protein, interleukin-6, and white blood cells. Conclusions: This pilot study provides insufficient evidence to determine the efficacy of convalescent plasma use as a therapeutic option for critically ill COVID-19 patients.

scholarly journals Internal barriers to efficiency: why disinvestments are so difficult. Identifying and addressing internal barriers to disinvestment of health technologies

2021 ◽  
pp. 1-16
Author(s):  
Bjørn Hofmann
Keyword(s):  
Health Care ◽  
Health Economics ◽  
Cognitive Biases ◽  
Care Practice ◽  
Core Concept ◽  
Health Care Practice ◽  
Health Technologies ◽  
Sound Foundation ◽  
Internal Barriers ◽  
Efficient Care

Abstract Although efficiency is a core concept in health economics, its impact on health care practice still is modest. Despite an increased pressure on resource allocation, a widespread use of low-value care is identified. Nonetheless, disinvestments are rare. Why is this so? This is the key question of this paper: why are disinvestments not more prevalent and improving the efficiency of the health care system, given their sound foundation in health economics, their morally important rationale, the significant evidence for a long list of low-value care and available alternatives? Although several external barriers to disinvestments have been identified, this paper looks inside us for mental mechanisms that hamper rational assessment, implementation, use and disinvestment of health technologies. Critically identifying and assessing internal inclinations, such as cognitive biases, affective biases and imperatives, is the first step toward a more rational handling of health technologies. In order to provide accountable and efficient care we must engage in the quest against the figments of our minds; to disinvest in low-value care in order to provide high-value health care.

scholarly journals Preferences for everyday living inventory (PELI): study protocol for piloting a culture-sensitive and setting-specific translated instrument in German care settings (PELI-D)

BMJ Open ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. e030268
Author(s):  
Tobias Ingo Stacke ◽  
Johannes Michael Bergmann ◽  
Armin Michael Ströbel ◽  
René Müller-Widmer ◽  
Daniel Purwins ◽  
...  
Keyword(s):  
Pilot Study ◽  
Older People ◽  
Study Protocol ◽  
Personal Information ◽  
Care Process ◽  
Internal Quality ◽  
Care Practice ◽  
Individual Preferences ◽  
Need Of Care ◽  
Everyday Living

IntroductionRegardless of the healthcare setting, person-centred care and its implementation in caring for older people are a central issue for those who are responsible as professional caregivers and for those in need of care within the care process. Both aspects encompass the possibility of recognising personal preferences. To provide person-centred care, professional caregivers need to know about the individual preferences of the persons being cared for. Therefore, the PELI (an acronym for ‘Preferences for Everyday Living Inventory’) instrument was developed at the Polisher Research Institute (USA) for the systematic recording of individual preferences of older people in need of care. There is currently no comparable instrument available in the German language.MethodsAs part of the proposed project PELI-D, all versions of the original PELI instrument (nursing home version) were (1) culture-sensitively translated into German and will be (2) examined in a pilot study for their reliability, feasibility and practicability. For the project PELI-D, we worked together with our practice partners in Germany (Diaconia and Caritas in North Rhine-Westphalia) and collaborated with our partners in the USA who developed the PELI instrument. This study protocol focuses on the pilot study, which will be conducted by the German Center for Neurodegenerative Diseases (DZNE) (site Witten).Ethics and disseminationThis study was approved by the internal quality control committee of the DZNE (ID number: WI029 PELI-D) and by the ethics committee of the German Society of Nursing Science Duisburg branch office (ID number: 18-010). All personal information will be deidentified with a specific identification code and stored in a secured location apart from the rest of the study data. Only qualified and study-related staff will be allowed access to the data. The results of the study will be distributed nationally and internationally through peer-reviewed journals, conferences and journals for nursing care practice.

scholarly journals Ongoing processes of managing consent: the empirical ethics of using video-recording in clinical practice and research

2011 ◽  
Vol 6 (4) ◽  
pp. 179-185 ◽  
Author(s):  
Michelle O'Reilly ◽  
Nicola Parker ◽  
Ian Hutchby
Keyword(s):  
Health Care ◽  
Video Recording ◽  
Empirical Ethics ◽  
Video Data ◽  
Care Practice ◽  
Reflecting Team ◽  
Recording Equipment ◽  
Health Care Practice ◽  
Ethical Concerns ◽  
Sensitive Topics

Using video to facilitate data collection has become increasingly common in health research. Using video in research, however, does raise additional ethical concerns. In this paper we utilize family therapy data to provide empirical evidence of how recording equipment is treated. We show that families made a distinction between what was observed through the video by the reflecting team and what was being recorded onto videotape. We show that all parties actively negotiated what should and should not go ‘on the record’, with particular attention to sensitive topics and the responsibility of the therapist. Our findings have important implications for both clinical professionals and researchers using video data. We maintain that informed consent should be an ongoing process and with this in mind we present some arguments pertaining to the current debates in this field of health-care practice.

scholarly journals Effect of treating periodontitis on C-reactive protein levels: a pilot study

2002 ◽  
Vol 2 (1) ◽  
Author(s):  
Kimmo Mattila ◽  
Marja Vesanen ◽  
Ville Valtonen ◽  
Markku Nieminen ◽  
Timo Palosuo ◽  
...  
Keyword(s):  
Pilot Study ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein

scholarly journals Postoperative Albumin Drop Is a Marker for Surgical Stress and a Predictor for Clinical Outcome: A Pilot Study

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Martin Hübner ◽  
Styliani Mantziari ◽  
Nicolas Demartines ◽  
François Pralong ◽  
Pauline Coti-Bertrand ◽  
...  
Keyword(s):  
Stress Response ◽  
Pilot Study ◽  
Clinical Outcomes ◽  
Surgical Stress ◽  
Major Surgery ◽  
Surgical Trauma ◽  
Once Daily ◽  
Reactive Protein ◽  
Estimated Blood Loss ◽  
Postoperative Stress

Background. Surgical stress during major surgery may be related to adverse clinical outcomes and early quantification of stress response would be useful to allow prompt interventions. The aim of this study was to evaluate the acute phase protein albumin in the context of the postoperative stress response.Methods. This prospective pilot study included 70 patients undergoing frequent abdominal procedures of different magnitude. Albumin (Alb) and C-reactive protein (CRP) levels were measured once daily starting the day before surgery until postoperative day (POD) 5. Maximal Alb decrease (Alb Δ min) was correlated with clinical parameters of surgical stress, postoperative complications, and length of stay.Results. Albumin values dropped immediately after surgery by about 10 g/L (42.2±4.5 g/L preoperativelyversus33.8±5.3 g/L at day 1,P<0.001). Alb Δ min was correlated with operation length (Pearsonρ=0.470,P<0.001), estimated blood loss (ρ=0.605,P<0.001), and maximal CRP values (ρ=0.391,P=0.002). Alb Δ min levels were significantly higher in patients having complications (10.0±5.4versus6.1±5.2,P=0.005) and a longer hospital stay (ρ=0.285,P<0.020).Conclusion. Early postoperative albumin drop appeared to reflect the magnitude of surgical trauma and was correlated with adverse clinical outcomes. Its promising role as early marker for stress response deserves further prospective evaluation.

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