HYGIENIC ANALYSIS OF WORKING CONDITIONS IN THE PRODUCTION OF TABLETS AND CAPSULE

2021 ◽  
pp. 39-44
Author(s):  
S.V. Arabei ◽  
◽  
А.V. Hindziuk ◽  

In the present research, the working conditions of workers employed in the production of medicines in the form of tablets and capsules of a modern enterprise of the pharmaceutical industry have been studied. Based on the results of attestation of workplaces and data of industrial laboratory control of the factors of the production environment for the period from 2016 to 2019, a complex of harmful production factors at workplaces was determined and a comprehensive hygienic assessment of the working conditions of a general purpose machine operator of chemical and pharmaceutical preparations, packaging machine operator, stacker-packer and processor of technological containers and tares. It has been established that the labor activity of the leading professional groups of workers in production is associated with the influence of a predominantly chemical factor due to the presence of harmful chemicals in the air of the working area. According to the data obtained, the air of the working area at the workplace of the operator of a wide profile of chemical and pharmaceutical preparations of the tableting and filling of capsules section is contaminated with harmful chemicals (doxycycline, nystatin, lincomycin, rifampicin, tetracycline, etc.), the concentrations of which exceed the maximum permissible. A hygienic assessment of the parameters of the microclimate, noise and tension of the labor process at the studied workplaces established that there are no deviations from hygienic standards and the working conditions according to these factors are permissible. Thus, the data obtained allow us to conclude that the working conditions of the operator of a wide profile of chemical and pharmaceutical preparations belong to class 3.3, the stacker-packer — 3.1, and the working conditions of the operator of filling and packaging machines and the processor of technological containers and tares are assessed as acceptable.

Author(s):  
I. V. Bukhtiyarov

The article presents the results of the analysis of health, working conditions and prevalence of adverse production factors, the structure of the detected occupational pathology in the working population of the Russian Federation. The article presents Statistical data on the dynamics of the share of workplaces of industrial enterprises that do not meet hygienic standards, occupational morbidity in 2015-2018 for the main groups of adverse factors of the production environment and the labor process. The indicators of occupational morbidity over the past 6 years in the context of the main types of economic activity, individual subjects of the Russian Federation, classes of working conditions, levels of specialized occupational health care. The role of the research Institute of occupational pathology and occupational pathology centers in solving organizational, methodological and practical tasks for the detection, treatment, rehabilitation and prevention of occupational diseases is shown. The basic directions of activity in the field of preservation and strengthening of health of workers, and also safety at a workplace are defined.


Author(s):  
Elena Abrakhmanova ◽  
Lyaylya Masyagutova ◽  
Aynur Gabbasov ◽  
Akhat Bakirov ◽  
Galina Gimranova ◽  
...  

The work presents data analysis of the results of special assessment of working conditions for workers of various branches of economy in the Bashkortostan Republic. Results of special assessment of working conditions (SAWC) and medical examinations were used for the analysis. It is noted, that some professional groups, for example, persons performing their work in the sphere of agriculture, have no exposure to the biological factor. Construction workers were not exposed to industrial vibration, while the noise level for half of the analyzed cases was of class 2.0, although in most cases, industrial noise and vibration have single source. Proportion of facilities that revealed a discrepancy between levels of harmful industrial factors and requirements of sanitary legislation remains high. The greatest share of objects does not correspond to sanitary and epidemiological requirements according to the chemical and physical factor. At the moment, SAWC does not fully reflect the working conditions of employees in different sectors of production. Underestimation of its influence on working conditions of workers is typical for a considerable number of professional groups and individual jobs. Analysis on the basis of SAWC is not sufficient for a hygienic assessment of the impact of production environment factors and labour process on health and requires comprehensive assessment methods.


2021 ◽  
pp. 38-42
Author(s):  
L. F. Horzov ◽  
M. V. Krivtsova ◽  
E. Ya. Kostenko ◽  
M. I. Balega ◽  
V. I. Voitovich

One of the most socially important types of work is the work of medical workers. Due to the presence of a significant number of harmful and dangerous factors, the medical profession is divided into a separate group, which in turn is characterized by unique aspects of work. The work of doctors and nurses of different specialties of the dental profile differs significantly in the density of the working day, the volume and nature of professional activities; responsibility for the life of the patient, which affects many physiological processes. The purpose. Assessment and comparative characterization of the presence of occupational risks in the dental field, which are daily exposed to factors of aggressive and dangerous nature, as well as the development of a set of preventive measures aimed at reducing occupational morbidity. Materials and methods. Hygienic research of working conditions of medical staff of the University Dental Clinic in the form of a questionnaire. Statistical analysis of data of special assessment of working conditions; sanitary and hygienic characteristics, acts, maps of cases of nosocomial diseases; laboratory and instrumental research conducted as part of production control; dosimetric control, air sampling with subsequent sowing on the nutrient medium of IPA. Results. It was found that in the studied premises, the total microbial count varied from 756 ± 0.8 CFU / 1m3 to 6497 ± 3.4 CFU / 1m3. In most medical institutions, the level of artificial lighting in the workplaces of medical workers was insufficient. The largest negative contribution was provided by such production factors as: labor intensity and intensity - 26.41%; physical: noise, vibration, non-ionizing and ionizing radiation - 25.32%; chemical - 12.77%. The total contribution of the main factors was 91.78%. Assessment of working conditions is based on hygienic criteria to assess the degree of deviations of the parameters of the production environment and labor process from the current hygienic standards, as well as after analysis and processing of data submitted by employees in the format of their questionnaires. In this regard, the distribution of harmful production factors and their degree of impact on the health of medical personnel was established with the help of multifactor analysis. Conclusions. Thus, the research interprets the results, which clearly in the format of a specific percentage, identify those factors that have a strong driving impact on the health of dental professionals. The most substantiated are such production factors as: chemical (exposure to drugs and chemicals), physical (noise and vibration, non-ionizing and ionizing radiation), the severity and intensity of the labor process, lighting (non-compliance with regulations for artificial lighting in the workplace) and microclimate and biological (work with biological, potentially contaminated material, samples, patients), non-ionizing and ionizing radiation, labor intensity (tension of the visual organs).


10.12737/6676 ◽  
2014 ◽  
Vol 8 (1) ◽  
pp. 0-0
Author(s):  
Шевелева ◽  
T. Sheveleva ◽  
Честнова ◽  
Tatyana Chestnova

The literary review of hygienic assessment of working conditions and health of workers of rubber industry is carried out. This paper is devoted to necessity of studying harmful factors affecting on workers of rubber production and hygienic evaluation of the working conditions of the basic professional groups at the present stage of industry development, according to combined action of various chemical and physical factors. It is established that in the manufacture of rubber products along with highly mechanized production processes, there are numerous time-consuming operation. During the hygiene assessment of work condition it is found that the chemical factor retains a dominant role in the diversity of the production environment. The workers in the chemical industries in their work are subjected to combined effects of various toxic substances in concentrations that often exceed maximum allowable concentrations which, coming together in unmanaged reactions, create various combinations of several substances, combined with the action of physical factors associated with high labor intensity.


2021 ◽  
Vol 65 (1) ◽  
pp. 50-53
Author(s):  
Natalya I. Nikolaeva ◽  
Andrey S. Filin ◽  
Glafira S. Dikaya

Introduction. During oil production, drillers are exposed to harmful occupation production factors: noise, vibration, the severity and intensity of work, microclimatic conditions, oil, and components. The purpose of the study was to conduct comprehensive investigations of working conditions and health status, to assess the occupational risk of drillers at an oil production enterprise. Material and methods. The work was carried out within the framework of the special assessment of working conditions carried out according to the plan. The influence of occupational factors of the production environment on workers’ health was assessed by indices of occupational morbidity and the results of periodic medical examinations of drillers servicing the drilling rig for oil production driller 5000.320 ERO for the period 2013-2018. Results. Analysis of the measured parameters of harmful occupation factors indicates noise, vibration, and psychophysiological indices to be the leading indices of working conditions that affect the employees’ health. The general assessment of employees’ working conditions corresponds to the class- 3.3 (harmful), the category of occupational risk - high (unbearable). The source of harmful effects on workers is the equipment of the drilling rig 5000.320 ERO. Analysis of medical documents drillers over 5 years revealed a link between working conditions and the development of occupational diseases (vibration disease, sensorineural hearing loss); between operating conditions and the development of career-related diseases: musculoskeletal system (arthrosis, arthritis, osteochondrosis, etc.); the peripheral nervous system (radiculitis, plexitis, polyneuritis, etc.); diseases of the respiratory system (bronchitis, pneumonia, asthma, and respiratory diseases, etc.). Conclusion. To prevent the negative impact of harmful production factors at the enterprise it is necessary to provide many preventive measures: automation, mechanization, sealing of equipment, employees have to be equipped with personal protective equipment, improving the quality of preliminary and periodic medical examinations.


2018 ◽  
Vol 22 (1) ◽  
pp. 212-216
Author(s):  
A.V. Basanets ◽  
M.M. Bulavko

The work carried out the comparative evaluation of sanitary and hygienic working conditions of mining workers of breakage face and machinists of shearer mining machines of the SE "Lvivvuhillia". The technology of underground coal mining caused by the interconnected set of basic and auxiliary production processes of extraction and transportation of coal, as well as conducting appropriate preparatory works. The main mining occupations, without which it is impossible to carry out the coal mining cycle of works, include "mining worker of breakage face" (MWBF) and "machinist of shearer mining machines" (МSMM). The aim of the study was the estimation of the influence of sanitary and hygienic working conditions of MWBF and МSMM on the development of deforming arthrosis. The research evaluated the sanitary and hygienic working conditions of mining workers of breakage face and machinists of shearer mining machines of the SE "Lvivvuhillia" on the basis of the processed and generalized data of 40 sanitary and hygienic characteristics of labor activity (29 MWBF and 11 МSMM) for 2015-2017. The obtained data were compared with the normative values of the State Sanitary Norms and Regulations according to the Order № 248 dated from 08.04.2014 "Hygienic Classification of Labor on the Indicators of Hazard and Danger of the Factors of the Production Environment, the Severity and Stress of the Labor Process". Installed that the levels of the main production factors of the development of deforming arthrosis in the workplaces of miners of the main occupations exceeded the approved hygienic standards: moving cargo over a considerable distance (more than 5 meters) among МSMM - to 2072 kg/m, among MWBF - by 1.62 - to 28424 kg/m; lifting and moving goods among MWBF - by 2.2 heavier loads than norm (33 kg against 15 kg, respectively); the static load of miners was excessive among МSMM by 1.22, among MWBF - by 2.31 (122040 kg/f; 231220 kg/f, respectively, against the norm of 100000 kg/f); prolonged stay in a forced working position among МSMM - by 2.52 longer than norm (63 kg/f against 25 kg/f, respectively), among MWBF - by 3.40 (85 kg/f against 25 kg/f, respectively); MWBF were in the working position on the knees - by 6.5 longer than norm (65 kg/f against 10 kg/f, respectively), МSMM - by 2,6 (26 kg/f against 10 kg/f, respectively). So, the mining and geological characteristic of deposits of the Lviv-Volyn coal basin promotes the creation of dangerous working conditions for miners of the main occupations, causing the risk of development of musculoskeletal system pathology, including deforming arthrosis. The main risk factors of development of deforming arthrosis among the miners of these occupations are defined such factors of the production environment as: the severity and intensity of the labor process.


2021 ◽  
Vol 100 (9) ◽  
pp. 975-979
Author(s):  
Alla V. Zheglova

Introduction. One of the main factors shaping the health of the working population is occupation conditions. According to official statistics, about a quarter of employees are exposed to production factors that do not meet sanitary standards. Materials and methods. A study of the working conditions and health of workers of the leading professional groups of mining and mechanical engineering enterprises, including an assessment of the occupational doses of noise and vibration, was conducted; morbidity with a temporary disability (TDA), occupational morbidity, clinical and laboratory indicators, including the leading indicators of hemodynamics, integral indicators of the cardiovascular system, the rate of acceleration of ageing, types of adaptive reactions of the body, the analysis of endothelin concentration, the state of the antioxidant status and lipid spectrum, indicators of rheovasography and stimulation electroneuromyography of the extremities, bone-dystrophic changes according to radiography and ultrasound bone sonometry, psychological testing data. Results. The main harmful factors of working conditions of workers of the leading professional groups of mining and machine-building enterprises are noise, vibration (general and local), and the labour process’s severity. According to the results of the analysis of the incidence of TDA, diseases of risk at all studied enterprises are the pathology of the respiratory and musculoskeletal systems. The first rank place in the structure of occupational pathology is occupied by vibration disease. An increase in the integral indicators of the cardiovascular system activity, characterizing the tension of adaptive mechanisms in the group of trained workers, was revealed. According to the study, the characteristic early signs of markers of the risk of developing occupational diseases are an increase in the concentration of endothelin and a decrease in the rate of excitation along with the motor and sensory fibres of the peripheral nerves. Conclusion. Based on the results obtained, prevention and rehabilitation programs have been developed, taking into account the calculated probationary doses of noise and vibration, the detected early signs of occupational diseases, aimed at preventing the development of health disorders and restoring damaged functions in workers exposed to physical factors of the production environment.


Author(s):  
A. V. Derevnina ◽  
N. I. Izmerova ◽  
I. Y. Chistova

To identify tumors and assess the risks of malignancy of different epithelial skin neoplasms working with industrial carcinogens, not only the influence of production factors was considered, but also visual diagnostic methods (dermatoscopy) were used, according to the assessment of working conditions.


Author(s):  
A. G. Chebotarev ◽  
O. V. Sokur

Metallurgy is exposed to a complex of production factors, the levels of which often exceed the hygienic standards. Working conditions are characterized by grade 3 (harmful) 2-4 degrees, which determine the level of occupational morbidity (PZ). The PP indicator at ferrous metallurgy plants in recent years has fluctuated from 11.9 to 20.2 cases per 10,000 employees that have passed their MEP. In the structure of PZ 59.5% of cases are respiratory diseases. A trend has been established in these enterprises to increase deaths in the workplace, mainly from diseases of the cardiovascular system.


Author(s):  
Vadim M. Vasilkevich ◽  
Ruslan V. Bogdanov ◽  
Elena V. Drozdova

Introduction. The working conditions of pharmaceutical industry workers are characterized by the combined effect of unfavorable factors of the production environment, among which the leading one is chemical. The aim of study is to substantiate the basic principles and criteria for hygienic regulation of pharmaceutical products in their production to ensure safe working conditions for employees based on the results of their own research and existing requirements of technical regulations. Materials and methods. Analysis of working conditions and the prevalence of health disorders in pharmaceutical workers (according to literature data), toxicological studies of pharmaceutical substances on laboratory animals, scientific justification of hygiene standards in the air of the working area. Results. Among employees of the pharmaceutical industry, the predominant forms of production-related health disorders are diseases of the respiratory system, as well as skin dermatitis of allergic origin, liver and biliary tract diseases. Based on the results of experimental studies of domestic pharmaceutical products for the treatment of cardiovascular, oncological and mental diseases that have priority socio-economic significance, the basic principles and features of the practice of justifying the hygienic standards of medicines in the air of the working area are developed and systematized. Conclusions. During hygienic rationing of medicines, it is necessary to use a differentiated approach that allows, based on the analysis of information about the chemical structure, physical and chemical characteristics, production conditions, pharmacotherapeutic activity, and the results of studying the toxic effect in an experiment on laboratory animals, to determine the maximum permissible content in the air of the working area of medicines or to justify the prohibition of isolation with reasoned recommendations for their safe production.


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