Delayed sedimentary grains

Author(s):  
Sebastien Carretier ◽  
Laure Guerit ◽  
Rebekah Harries ◽  
Vincent Regard ◽  
Pierre Maffre ◽  
...  

<p>River sediment grains are transported and stored episodically in different reservoirs (terraces, alluvial fans, foreland basin, etc.). The residence time of sediment grains in each reservoir has important implications for the paleo-environmental interpretation established from these grains, and their stratigraphic record, as well as for soil contamination, when these grains come from contaminated sources. The recycling of old sediments, via erosion of an old reservoir (e.g. foreland basin erosion), is a known problem. What is less well recognised is that the recycling of a minority of very old grains can strongly bias the average residence time of a grain population deposited in a stratum. In this case, the time-dependent paleo-environmental properties of a population of grains, such as the degree of weathering, or the concentration of cosmogenic isotopes, can then be biased. Several lines of evidence for this phenomenon, inherent to fluvial transport processes, have emerged, though reconstructing the residence time distribution of a grain population over long times (>>ka) remains a challenge. Using a landscape evolution model coupled with grain transport, we show that at the scale of a piedmont, grains can remain several hundred ka before being evacuated. At the scale of a river in Northern Chile, we used the concentration of 10Be in individual pebbles to show that some pebbles remain stored for several tens of ka before being evacuated to the river outlet. In addition, the distribution of residence times can also provide information on the nature of the diffusive processes that control the fluxes of exported sediment. These results suggest that the characterisation of grain-by-grain properties in a grain population can not only help to avoid possible interpretation biases but also provide constraints for models of long-term fluvial sediment outfluxes.  </p>

Author(s):  
D.V. Lipatov ◽  
◽  
S.A. Skladchikov ◽  
N.P. Savenkova ◽  
V.V. Novoderezkin ◽  
...  

Background. The avalanche-like growth of intravitreal injections in the world has significantly increased interest in the hemodynamics of the processes that occur in the eye when a drug is injected into the vitreous cavity. Every year, the number of intravitreally used drugs and promising areas in which they can be used is growing. This also applies to the creation of new combined medicines and the development of drugs with a long-term therapeutic effect. Aims. Create mathematical model of eyeball to evaluate the movement of the drug substance in it; to estimate the time of the drug's presence in the eye cavity before its complete removal, to characterize the ways of its removal from the eye cavity; to assess the significance of posterior vitreous detachment during the time when the drug is present in the eye cavity; to evaluate the effect on the hydrodynamics of the depth of drug administration. Results. When the drug is administered closer to the center of the eyeball, its residence time increases in comparison with the parietal administration. With a complete posterior detachment of the vitreous body, the time of finding the drug in the eye is prolonged compared to its absence. The obtained results of mathematical modeling of the movement of the drug administered intravitreally cannot be mechanically transferred to the human eye, due to the more complex structure of the latter. Key words: intravitreal injections, vitreous body, mathematic computing.


2021 ◽  
Vol 34 (1) ◽  
pp. 23-27
Author(s):  
Heather K. Knych ◽  
Jennifer Janes ◽  
Laura Kennedy ◽  
Daniel S. McKemie ◽  
Rick M. Arthur ◽  
...  

Bisphosphonates are potent anti-resorptive agents that have the potential to adversely affect bone healing in equine athletes, and normal bone adaption in young racehorses. A concern exists that bisphosphonate inhibition of normal bone metabolism could lead to increased bone fractures during high-intensity exercise. We found only a single report describing concentrations of tiludronate in the bone of horses, and no studies describing clodronate. Knowledge of the residence time in bone could allow for a better understanding of the long-term effects of these compounds. Our objectives were to develop a method for detection of bisphosphonates in bone and add to the limited information available regarding the disposition of these drugs in the bone of horses. Two horses received clodronate and 2 tiludronate disodium. Postmortem collection of bones and teeth occurred either 4 or 30 d post drug administration. Additionally, postmortem blood, synovial fluid, aqueous humor, and bone samples from racehorses with various histories of bisphosphonate administration were collected, and concentrations determined using the developed LC-MS/MS method. Bisphosphonates were detected in bones and teeth tested at 4 and 30 d. In a postmortem sample, clodronate was detected in bone from a horse with reported administration 18 mo prior; clodronate was not detected in other sample types collected from this horse. Bisphosphonates reside in bone for extended periods of time, which could lead to potential long-term effects, increasing the potential for bone fractures in young and/or athletic horses.


2020 ◽  
pp. 1733-1740 ◽  
Author(s):  
A. Millares ◽  
J. Herrero ◽  
M. Bermúdez ◽  
J.F. Leiva ◽  
M. Cantalejo

Materials ◽  
2020 ◽  
Vol 13 (12) ◽  
pp. 2709 ◽  
Author(s):  
Nicole Bandow ◽  
Michael D. Aitken ◽  
Anja Geburtig ◽  
Ute Kalbe ◽  
Christian Piechotta ◽  
...  

The potential release of hazardous substances from polymer-based products is currently in the focus of environmental policy. Environmental simulations are applied to expose such products to selected aging conditions and to investigate release processes. Commonly applied aging exposure types such as solar and UV radiation in combination with water contact, corrosive gases, and soil contact as well as expected general effects on polymers and additional ingredients of polymer-based products are described. The release of substances is based on mass-transfer processes to the material surfaces. Experimental approaches to investigate transport processes that are caused by water contact are presented. For tailoring the tests, relevant aging exposure types and release quantification methods must be combined appropriately. Several studies on the release of hazardous substances such as metals, polyaromatic hydrocarbons, flame retardants, antioxidants, and carbon nanotubes from polymers are summarized exemplarily. Differences between natural and artificial exposure tests are discussed and demonstrated for the release of flame retardants from several polymers and for biocides from paints. Requirements and limitations to apply results from short-term artificial environmental exposure tests to predict long-term environmental behavior of polymers are presented.


Author(s):  
Michael J. Truex ◽  
Amoret L. Bunn ◽  
Mart Oostrom ◽  
K. C. Carroll ◽  
Dawn M. Wellman

The U.S. Department of Energy is responsible for risk reduction and cleanup of its nuclear weapons complex. Remediation strategies for some of the contamination may include techniques that mitigate risk, but leave contaminants in place. Monitoring to verify remedy performance and long-term mitigation of risk is key to implementing these strategies and can be a large portion of the total cost of remedy implementation. Especially in these situations, there is a need for innovative monitoring approaches that move away from the cost- and labor-intensive point-source monitoring. In this paper, alternative approaches for monitoring are presented for vadose zone, groundwater, groundwater/surface water interface, and surface water. To illustrate integrated, systems-based monitoring, this paper focuses on vadose zone contaminant remediation to mitigate impact to groundwater. In this context, vadose zone contamination is a source, or potential source, to groundwater plumes. The monitoring design uses a systems-based approach focused on developing a conceptual site model that highlights key features that control contaminant flux to groundwater. These features are derived considering the unsaturated flow and contaminant transport processes in the vadose zone and the nature of the waste discharge. Diagnostic properties and/or parameters related to both short- and long-term contaminant flux to groundwater can be identified and targeted for monitoring. The resolution of monitoring data needed to correspond to a functionally useful indicator of flux to groundwater can be estimated using quantitative analyses and the associated unsaturated flow properties relevant to the targeted site and vadose zone features. This monitoring design approach follows the process of developing a quantitative conceptual model suitable for supporting projections of future flux to groundwater. Support for such projections is important because it is likely that, in many cases, remediation decisions for the vadose zone will need to be made based all or in part on projected impacts to groundwater, and monitoring will then be applied to verify that remedy goals are being met.


2020 ◽  
Author(s):  
Shlomi Ziskin Ziv ◽  
Chaim I. Garfinkel

<p>Understanding the sinks, sources and transport processes of stratospheric trace gases can improve our prediction of mid to long term climate change. In this study we consider the processes that lead to variability in stratospheric water vapor. We perform a Multiple Linear Regression(MLR) on the SWOOSH combined anomaly filled water vapor product with ENSO, QBO, BDC, mid-tropospheric temperature, and CH4 as predictors, in an attempt to find the factors that most succinctly explain observed water vapor variability. We also consider the fraction of entry water vapor variability that can be accounted for by variations of the cold point temperature as an upper bound on how much water vapor variability is predictable from large scale processes. Several periods in which the MLR fails to account for interannual variability are treated as case studies in order to better understand variability in entry water not governed by these large scale processes.</p>


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