Epidemics and Human Mobility

2021 ◽  
Author(s):  
Theo Geisel
Keyword(s):  
Infectious Diseases ◽  
Recent Work ◽  
Statistical Data ◽  
Multiple Scales ◽  
Human Mobility ◽  
Traffic Networks ◽  
Epidemic Spreading ◽  
Endemic Diseases ◽  
And Control

<p>The severity of infectious diseases and epidemics increases drastically, when pathogens start being transmitted between humans, as thereby they can dispose of human traffic networks for their spreading. This can transform an epidemic into a worldwide threatening pandemic, as the current COVID-19 crisis has shown. Traffic networks exist on multiple scales and the spreading of pathogens exhibits superdiffusive properties. This talk will emphasize and analyze the key role of human mobility for the modeling, forecast, and control of epidemic spreading. A major problem is posed by the limited availability of statistical data on human mobility. Various proxies are now utilized since we suggested dollar bills as proxies for human moblity.  Recent work on endemic diseases in populations open to migration will be discussed. </p>

scholarly journals CHNS Modeling for Study and Management of Human–Water Interactions at Multiple Scales

Water ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1699 ◽  
Author(s):  
Kumaraswamy Ponnambalam ◽  
S. Jamshid Mousavi
Keyword(s):  
Large Scale ◽  
Multiple Scales ◽  
Water Cycle ◽  
Integrated Water Resources Management ◽  
Natural Systems ◽  
Institutional Issues ◽  
And Control ◽  
The Impact ◽  
Global Hydrology

This paper presents basic definitions and challenges/opportunities from different perspectives to study and control water cycle impacts on society and vice versa. The wider and increased interactions and their consequences such as global warming and climate change, and the role of complex institutional- and governance-related socioeconomic-environmental issues bring forth new challenges. Hydrology and integrated water resources management (IWRM from the viewpoint of an engineering planner) do not exclude in their scopes the study of the impact of changes in global hydrology from societal actions and their feedback effects on the local/global hydrology. However, it is useful to have unique emphasis through specialized fields such as hydrosociology (including the society in planning water projects, from the viewpoint of the humanities) and sociohydrology (recognizing the large-scale impacts society has on hydrology, from the viewpoint of science). Global hydrological models have been developed for large-scale hydrology with few parameters to calibrate at local scale, and integrated assessment models have been developed for multiple sectors including water. It is important not to do these studies with a silo mindset, as problems in water and society require highly interdisciplinary skills, but flexibility and acceptance of diverse views will progress these studies and their usefulness to society. To deal with complexities in water and society, systems modeling is likely the only practical approach and is the viewpoint of researchers using coupled human–natural systems (CHNS) models. The focus and the novelty in this paper is to clarify some of these challenges faced in CHNS modeling, such as spatiotemporal scale variations, scaling issues, institutional issues, and suggestions for appropriate mathematical tools for dealing with these issues.

scholarly journals SOCIAL DISTANCING STRATEGIES AGAINST DISEASE SPREADING

Fractals ◽  
2013 ◽  
Vol 21 (03n04) ◽  
pp. 1350019 ◽  
Author(s):  
L. D. VALDEZ ◽  
C. BUONO ◽  
P. A. MACRI ◽  
L. A. BRAUNSTEIN
Keyword(s):  
Infectious Diseases ◽  
Healthy Individual ◽  
Percolation Theory ◽  
Quenched Disorder ◽  
Epidemic Spreading ◽  
Heterogeneous Distribution ◽  
Percolation Process ◽  
Social Distancing ◽  
Disease Spreading

The recurrent infectious diseases and their increasing impact on the society has promoted the study of strategies to slow down the epidemic spreading. In this review we outline the applications of percolation theory to describe strategies against epidemic spreading on complex networks. We give a general outlook of the relation between link percolation and the susceptible-infected-recovered model, and introduce the node void percolation process to describe the dilution of the network composed by healthy individual, i.e., the network that sustain the functionality of a society. Then, we survey two strategies: the quenched disorder strategy where an heterogeneous distribution of contact intensities is induced in society, and the intermittent social distancing strategy where health individuals are persuaded to avoid contact with their neighbors for intermittent periods of time. Using percolation tools, we show that both strategies may halt the epidemic spreading. Finally, we discuss the role of the transmissibility, i.e., the effective probability to transmit a disease, on the performance of the strategies to slow down the epidemic spreading.

scholarly journals The effect of human mobility and control measures on the COVID-19 epidemic in China

2020 ◽  
Author(s):  
Moritz U.G. Kraemer ◽  
Chia-Hung Yang ◽  
Bernardo Gutierrez ◽  
Chieh-Hsi Wu ◽  
Brennan Klein ◽  
...  
Keyword(s):  
Human Mobility ◽  
Control Measures ◽  
Human Populations ◽  
Travel History ◽  
Mobility Data ◽  
Travel Restrictions ◽  
State Interventions ◽  
And Control ◽  
The Impact

AbstractThe ongoing COVID-19 outbreak has expanded rapidly throughout China. Major behavioral, clinical, and state interventions are underway currently to mitigate the epidemic and prevent the persistence of the virus in human populations in China and worldwide. It remains unclear how these unprecedented interventions, including travel restrictions, have affected COVID-19 spread in China. We use real-time mobility data from Wuhan and detailed case data including travel history to elucidate the role of case importation on transmission in cities across China and ascertain the impact of control measures. Early on, the spatial distribution of COVID-19 cases in China was well explained by human mobility data. Following the implementation of control measures, this correlation dropped and growth rates became negative in most locations, although shifts in the demographics of reported cases are still indicative of local chains of transmission outside Wuhan. This study shows that the drastic control measures implemented in China have substantially mitigated the spread of COVID-19.

scholarly journals Megacities as drivers of national outbreaks: the role of holiday travel in the spread of infectious diseases

2019 ◽  
Author(s):  
Ayesha S. Mahmud ◽  
Md. Iqbal Kabir ◽  
Kenth Engø-Monsen ◽  
Sania Tahmina ◽  
Baizid Khoorshid Riaz ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Large Scale ◽  
Disease Risk ◽  
Human Mobility ◽  
Mobile Phone Data ◽  
Dhaka City ◽  
Population Mobility ◽  
Time Data ◽  
The Impact

AbstractHuman mobility connects populations and can lead to large fluctuations in population density, both of which are important drivers of epidemics. Measuring population mobility during infectious disease outbreaks is challenging, but is a particularly important goal in the context of rapidly growing and highly connected urban centers in low and middle income countries, which can act to amplify and spread local epidemics nationally and internationally. Here, we combine estimates of population movement from mobile phone data for over 4 million subscribers in the megacity of Dhaka, Bangladesh, one of the most densely populated cities globally. We combine mobility data with epidemiological data from a household survey, to understand the role of population mobility on the spatial spread of the mosquito-borne virus chikungunya within and outside Dhaka city during a large outbreak in 2017. The peak of the 2017 chikungunya outbreak in Dhaka coincided with the annual Eid holidays, during which large numbers of people traveled from Dhaka to their native region in other parts of the country. We show that regular population fluxes around Dhaka city played a significant role in determining disease risk, and that travel during Eid was crucial to the spread of the infection to the rest of the country. Our results highlight the impact of large-scale population movements, for example during holidays, on the spread of infectious diseases. These dynamics are difficult to capture using traditional approaches, and we compare our results to a standard diffusion model, to highlight the value of real-time data from mobile phones for outbreak analysis, forecasting, and surveillance.

Role of Clinical Microbiology Laboratories in the Management and Control of Infectious Diseases and the Delivery of Health Care

2001 ◽  
Vol 32 (4) ◽  
pp. 605-610 ◽  
Author(s):  
L. B. Reller ◽  
M. P. Weinstein ◽  
L. R. Peterson ◽  
J. D. Hamilton ◽  
E. J. Baron ◽  
...  
Keyword(s):  
Health Care ◽  
Infectious Diseases ◽  
Delivery Of Health Care ◽  
Clinical Microbiology ◽  
And Control

scholarly journals Recent Advances in Immunotherapies Against Infectious Diseases

2020 ◽  
Author(s):  
Dharanidharan Ramamurthy ◽  
Trishana Nundalall ◽  
Sanele Cingo ◽  
Neelakshi Mungra ◽  
Maryam Karaan ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Infectious Diseases ◽  
Management Strategies ◽  
Emerging Diseases ◽  
Checkpoint Inhibition ◽  
Widespread Implementation ◽  
Cytokine Levels ◽  
Recent Developments ◽  
And Control

Abstract Immunotherapies are disease management strategies that target or manipulate components of the immune system. Infectious diseases pose a significant threat to human health as evidenced by countries continuing to grapple with several emerging and re-emerging diseases, the most recent global health threat being the SARS-CoV2 pandemic. As such, various immunotherapeutic approaches are increasingly being investigated as alternative therapies for infectious diseases, resulting in significant advances towards the uncovering of pathogen-host immunity interactions. Novel and innovative therapeutic strategies are necessary to overcome the challenges typically faced by existing infectious disease prevention and control methods such as lack of adequate efficacy, drug toxicity and the emergence of drug resistance. As evidenced by recent developments and success of pharmaceuticals such as monoclonal antibodies, immunotherapies already show abundant promise to overcome such limitations while also advancing the frontiers of medicine. In this review we summarize some of the most notable inroads made to combat infectious disease, over mainly the last 5 years, through the use of immunotherapies such as vaccines, monoclonal antibody-based therapies, T-cell-based therapies, manipulation of cytokine levels and checkpoint inhibition. Whilst its most general applications are founded in cancer treatment, advances made towards the curative treatment of HIV, tuberculosis, malaria, zika virus and, most recently COVID-19, reinforce the role of immunotherapeutic strategies in the broader field of disease control. Ultimately, the comprehensive specificity, safety and cost of immunotherapeutics will impact its widespread implementation.

scholarly journals Infectious Disease: Protecting Workers and Organizations-The Role of Compensation & Benefits

2020 ◽  
Vol 53 (1) ◽  
pp. 43-55
Author(s):  
William Marty Martin ◽  
Yvette Lopez ◽  
Thomas P. Flannery ◽  
Bill Dixon
Keyword(s):  
Infectious Diseases ◽  
Prevention And Control ◽  
Infection Prevention ◽  
Seasonal Influenza ◽  
Infection Prevention And Control ◽  
The Novel ◽  
Health And Wellness ◽  
Novel Coronavirus ◽  
And Control

Infectious diseases at work can be endemic such as seasonal influenza and emerging such as the novel coronavirus 2019. Infectious diseases have an impact on employees and other types of workers. Compensation and benefits professionals are often at the forefront of preventing workplace infections, addressing workplace infections, and ensuring the continuity of talent when workplace outbreaks and business shutdowns occur. This article provides an overview of pertinent laws, key compensation decisions, and ways to refocus existing benefit programs to meet the challenge of not only just safety, health, and wellness but also infection prevention and control.

scholarly journals Multisectoral Approach to Address Chikungunya Outbreaks Driven by Human Mobility: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 222 (Supplement_8) ◽  
pp. S709-S716
Author(s):  
Rashad Abdul-Ghani ◽  
Florence Fouque ◽  
Mohammed A K Mahdy ◽  
Qingxia Zhong ◽  
Samira M A Al-Eryani ◽  
...  
Keyword(s):  
Systematic Review ◽  
Human Mobility ◽  
Meta Analysis ◽  
Health Sector ◽  
Mobility Patterns ◽  
Migrant Populations ◽  
Virus Genotypes ◽  
High Level ◽  
And Control

Abstract Background The role of human mobility in the epidemiology of emerging Aedes-transmitted viral diseases is recognized but not fully understood. The objective of this systematic review and meta-analysis was to examine how human mobility patterns are driving chikungunya outbreaks. Methods Literature was systematically reviewed for studies on chikungunya prevalence in countries/territories with high-level evidence of human mobility-driven outbreaks, based on: (1) emergence of chikungunya outbreaks with epidemic chikungunya virus genotypes among displaced/migrant populations and their hosting communities; and (2) identification of imported index case(s) with epidemic genotypes phylogenetically related to the genotypes circulating during emerging or subsequent outbreaks. Results The meta-analysis of extracted prevalence data revealed that a large proportion of the population in countries/territories afflicted by outbreaks is still at risk of infection during future outbreaks. On the other hand, approximately one-half of suspected chikungunya cases could be infected with other co-circulating acute febrile illnesses. Conclusions We discussed in this paper how human mobility-driven chikungunya outbreaks can be addressed, and how the involvement of several sectors in addition to the health sector in multisectoral approaches (MSAs) is important for prevention and control of chikungunya and other Aedes-transmitted arboviral outbreaks.

The role of epidemiology in the prevention, diagnosis, and control of infectious diseases of fish

2001 ◽  
Vol 48 (4) ◽  
pp. 287-302 ◽  
Author(s):  
M.P. Georgiadis ◽  
I.A. Gardner ◽  
R.P. Hedrick
Keyword(s):  
Infectious Diseases ◽  
And Control
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