scholarly journals Bootstrap Aggregation for Model Selection in the Model-free Formalism

2021 ◽  
Author(s):  
Timothy Crawley ◽  
Arthur G. Palmer III

Abstract. The ability to make robust inferences about the dynamics of biological macromolecules using NMR spectroscopy depends heavily on the application of appropriate theoretical models for nuclear spin relaxation. Data analysis for NMR laboratory-frame relaxation experiments typically involves selecting one of several model-free spectral density functions using a bias-corrected fitness test. Here, advances in statistical model selection theory, termed bootstrap aggregation or bagging, are applied to 15N spin relaxation data, developing a multimodel inference solution to the model-free selection problem. The approach is illustrated using data sets recorded at four static magnetic fields for the bZip domain of the S. cerevisiae transcription factor GCN4.

2012 ◽  
Author(s):  
Kate C. Miller ◽  
Lindsay L. Worthington ◽  
Steven Harder ◽  
Scott Phillips ◽  
Hans Hartse ◽  
...  

2021 ◽  
Vol 13 (13) ◽  
pp. 2433
Author(s):  
Shu Yang ◽  
Fengchao Peng ◽  
Sibylle von Löwis ◽  
Guðrún Nína Petersen ◽  
David Christian Finger

Doppler lidars are used worldwide for wind monitoring and recently also for the detection of aerosols. Automatic algorithms that classify the lidar signals retrieved from lidar measurements are very useful for the users. In this study, we explore the value of machine learning to classify backscattered signals from Doppler lidars using data from Iceland. We combined supervised and unsupervised machine learning algorithms with conventional lidar data processing methods and trained two models to filter noise signals and classify Doppler lidar observations into different classes, including clouds, aerosols and rain. The results reveal a high accuracy for noise identification and aerosols and clouds classification. However, precipitation detection is underestimated. The method was tested on data sets from two instruments during different weather conditions, including three dust storms during the summer of 2019. Our results reveal that this method can provide an efficient, accurate and real-time classification of lidar measurements. Accordingly, we conclude that machine learning can open new opportunities for lidar data end-users, such as aviation safety operators, to monitor dust in the vicinity of airports.


1998 ◽  
Vol 30 (2) ◽  
pp. 227-243
Author(s):  
K. N. S. YADAVA ◽  
S. K. JAIN

This paper calculates the mean duration of the postpartum amenorrhoea (PPA) and examines its demographic, and socioeconomic correlates in rural north India, using data collected through 'retrospective' (last but one child) as well as 'current status' (last child) reporting of the duration of PPA.The mean duration of PPA was higher in the current status than in the retrospective data;n the difference being statistically significant. However, for the same mothers who gave PPA information in both the data sets, the difference in mean duration of PPA was not statistically significant. The correlates were identical in both the data sets. The current status data were more complete in terms of the coverage, and perhaps less distorted by reporting errors caused by recall lapse.A positive relationship of the mean duration of PPA was found with longer breast-feeding, higher parity and age of mother at the birth of the child, and the survival status of the child. An inverse relationship was found with higher education of a woman, higher education of her husband and higher socioeconomic status of her household, these variables possibly acting as proxies for women's better nutritional status.


2018 ◽  
Vol 7 (2.28) ◽  
pp. 312
Author(s):  
Manu Kohli

Asset intensive Organizations have searched long for a framework model that would timely predict equipment failure. Timely prediction of equipment failure substantially reduces direct and indirect costs, unexpected equipment shut-downs, accidents, and unwarranted emission risk. In this paper, the author proposes a model that can predict equipment failure by using data from SAP Plant Maintenance module. To achieve that author has applied data extraction algorithm and numerous data manipulations to prepare a classification data model consisting of maintenance records parameters such as spare parts usage, time elapsed since last completed maintenance and the period to the next scheduled maintained and so on. By using unsupervised learning technique of clustering, the author observed a class to cluster evaluation of 80% accuracy. After that classifier model was trained using various machine language (ML) algorithms and subsequently tested on mutually exclusive data sets with an objective to predict equipment breakdown. The classifier model using ML algorithms such as Support Vector Machine (SVM) and Decision Tree (DT) returned an accuracy and true positive rate (TPR) of greater than 95% to predict equipment failure. The proposed model acts as an Advanced Intelligent Control system contributing to the Cyber-Physical Systems for asset intensive organizations. 


1983 ◽  
Vol 40 (10) ◽  
pp. 1829-1837 ◽  
Author(s):  
David A. Schlesinger ◽  
Henry A. Regier

Fishes inhabiting subarctic and temperate zone lakes exhibit distinct optimal growth temperatures and temperature preferenda. However, within regional data sets, attempts to correlate fish yields with temperature variables have generally been unsuccessful. In our study, curvilinear relationships between "long-term mean annual air temperature" (TEMP) and sustained yields of three species were fitted using data from 23 intensively fished lakes in Canada and the northern United States. Optimum TEMP values for sustained yield were approximately −1.0, 1.5, and 2 °C, respectively, for lake whitefish (Coregonus clupeaformis), northern pike (Esox lucius), and walleye (Stizostedion vitreum vitreum). These differences suggest that the influence of temperature on sustained fish yields from subarctic and temperate zone lakes may, in the past, have been underestimated.


1999 ◽  
Vol 55 (12) ◽  
pp. 2005-2012 ◽  
Author(s):  
Anirban Ghosh ◽  
Manju Bansal

AA·TT and GA·TC dinucleotide steps in B-DNA-type oligomeric crystal structures and in protein-bound DNA fragments (solved using data with resolution <2.6 Å) show very small variations in their local dinucleotide geometries. A detailed analysis of these crystal structures reveals that in AA·TT and GA·TC steps the electropositive C2—H2 group of adenine is in very close proximity to the keto O atoms of both the pyrimidine bases in the antiparallel strand of the duplex structure, suggesting the possibility of intra-base pair as well as cross-strand inter-base pair C—H...O hydrogen bonds in the DNA minor groove. The C2—H2...O2 hydrogen bonds in the A·T base pairs could be a natural consequence of Watson–Crick pairing. However, the cross-strand interactions between the bases at the 3′-end of the AA·TT and GA·TC steps obviously arise owing to specific local geometry of these steps, since a majority of the H2...O2 distances in both data sets are considerably shorter than their values in the uniform fibre model (3.3 Å) and many are even smaller than the sum of the van der Waals radii. The analysis suggests that in addition to already documented features such as the large propeller twist of A·T base pairs and the hydration of the minor groove, these C2—H2...O2 cross-strand interactions may also play a role in the narrowing of the minor groove in A-tract regions of DNA and help explain the high structural rigidity and stability observed for poly(dA)·poly(dT).


Author(s):  
D. J. Dowrick ◽  
S. Sritharan

The attenuation of peak ground accelerations was studied for eight New Zealand earthquakes which occurred in the period 1987 to 1991. These events were of medium size with moment magnitudes in the range Mw = 5.8 - 6.7, with depth to centroids of the fault rupture ranging from 4 to 60 km. Attenuation of peak ground accelerations was examined for each event, based on the slope distance from the rupture surface to each strong motion data site. The mean regression attenuation curve for each event was compared with those derived by others using data sets from other parts of the world, allowance being made for source mechanism and depth. Excepting the 1988 Te Anau event, the other seven New Zealand events as a set closely match a Japanese model, but give significantly stronger accelerations than those predicted by the models from western USA and Europe.


2022 ◽  
Vol 163 (2) ◽  
pp. 40
Author(s):  
Anusha Pai Asnodkar ◽  
Ji Wang ◽  
B. Scott Gaudi ◽  
P. Wilson Cauley ◽  
Jason D. Eastman ◽  
...  

Abstract Transiting hot Jupiters present a unique opportunity to measure absolute planetary masses due to the magnitude of their radial velocity signals and known orbital inclination. Measuring planet mass is critical to understanding atmospheric dynamics and escape under extreme stellar irradiation. Here we present the ultrahot Jupiter system KELT-9 as a double-lined spectroscopic binary. This allows us to directly and empirically constrain the mass of the star and its planetary companion without reference to any theoretical stellar evolutionary models or empirical stellar scaling relations. Using data from the PEPSI, HARPS-N, and TRES spectrographs across multiple epochs, we apply least-squares deconvolution to measure out-of-transit stellar radial velocities. With the PEPSI and HARPS-N data sets, we measure in-transit planet radial velocities using transmission spectroscopy. By fitting the circular orbital solution that captures these Keplerian motions, we recover a planetary dynamical mass of 2.17 ± 0.56 M J and stellar dynamical mass of 2.11 ± 0.78 M ⊙, both of which agree with the discovery paper. Furthermore, we argue that this system, as well as systems like it, are highly overconstrained, providing multiple independent avenues for empirically cross-validating model-independent solutions to the system parameters. We also discuss the implications of this revised mass for studies of atmospheric escape.


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