The release of hydrolytic enzymes by the salivary glands and their content in the blood after unilateral nephrectomy

We studied the mechanisms of transformation of some salivary enzymes and established the real contribution of the salivary glands to the enzymatic homeostasis of the body in unilateral nephrectomy.The results were obtained that with unilateral nephrectomy, the content of amylase and pepsinogen in the blood increases, but its lipolytic activity remains unchanged, the volume of basal secretion of the salivary glands, the content and release of amylase by the parotid salivary gland increases. Unilateral nephrectomy stimulates the increment of pepsinogen by the gastric glands, and, accordingly, enhances its recreation from the blood, by the salivary glands. After unilateral nephrectomy, lipolytic activity and its secretion in saliva remain unchanged

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The determination of specificity, sensitivity and accuracy of core needle biopsy in the diagnosis of parotid and submandibular salivary glands tumors

Vojnosanitetski pregled ◽

10.2298/vsp170320001o ◽

2019 ◽

Vol 76 (9) ◽

pp. 921-928

Author(s):

Aleksandar Oroz ◽

Zorana Bokun ◽

Djordje Antonijevic ◽

Jasna Jevdjic

Keyword(s):

Salivary Gland ◽

Salivary Glands ◽

Core Needle Biopsy ◽

Needle Biopsy ◽

Tumor Tissue ◽

Submandibular Salivary Gland ◽

Histopathological Analysis ◽

Core Needle ◽

Parotid Salivary Gland ◽

Submandibular Salivary Glands

Background/Aim. The diagnosis of tumors of salivary glands relies heavily on radiological examination and biopsy of pathological tissue. The aim of this study was to investigate the sensitivity, specificity and accuracy of core needle biopsy in diagnosis of tumors of parotid and submandibular glands. Methods. This study was designed as a crosssectional clinical trial performed between May 2008 and ?ay 2015 at the Department of Otorhinolaryngology and Maxillofacial Surgery, Clinical Center Zemun, Belgrade, Serbia. The examinations included 200 patients among which 100 were diagnosed with tumors of parotid salivary glands and 100 with tumors of submandibular salivary glands. The core needle biopsy was undertaken in all cases where tumor was smaller than 2 cm, far from blood vessels and far from the deep layer of parotid gland. The histopathological analysis was performed to identify histological type of the lesion. Upon performing the surgical procedure and consequently the tumor tissue extirpation, tissue samples obtained were investigated for the definitive diagnosis. Results. The sensitivity of the procedure was 90.9% for parotid salivary gland and 74% for submandibular salivary gland, the specificity was 95.9% for parotid salivary gland and 93% for submandibular salivary gland and the accuracy was 94.7% for parotid salivary gland and 87% for submandibular salivary gland. Based on the histopathological findings of the salivary glands obtained using core needle biopsy of the tumor tissue, it was possible to differentiate between malignant and benign lesions. Conclusion. Current investigation points to the advantages and efficiency of core needle biopsy in diagnosis of tumors of parotid and submandibular salivary glands.

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Epidemiologic Characteristics of Salivary Gland Tumors in an Iranian Population

Shiraz E-Medical Journal ◽

10.5812/semj.107675 ◽

2021 ◽

Vol In Press (In Press) ◽

Author(s):

Nafise Shamloo ◽

Alireza Ghanadan ◽

Fahimeh Sadat Hashemian ◽

Maedeh Ghorbanpour

Keyword(s):

Salivary Gland ◽

Adenoid Cystic Carcinoma ◽

Salivary Glands ◽

Pleomorphic Adenoma ◽

Malignant Tumors ◽

The Body ◽

Salivary Gland Tumors ◽

Benign Tumors ◽

Cross Sectional ◽

Adenoid Cystic

Background: Salivary gland tumors include a wide variety of benign and malignant tumors in the oral and maxillofacial region. Although these tumors are not common, they are not rare. The prevalence of these tumors varies with regard to age, gender, and their location in the body. Objectives: This study aimed to evaluate the frequency of benign and malignant salivary gland tumors in patients referred to three referral hospitals in Tehran, Iran. Methods: This retrospective cross-sectional study examined the demographic and pathologic records of the patients with salivary gland tumors submitted to the Department of Pathology of Amir Alam, Loghman Hakim, and Shohada Hospitals from 2005 to 2016. In this study, the histological variants of salivary gland tumors and clinical parameters such as age, gender, and the location of the tumor were examined. The clinical data were analyzed using SPSS software version 21. Results: Of 137632 patient records, 1180 cases were salivary gland tumors. Pleomorphic adenoma in 794 cases (67.3%) and adenoid cystic carcinoma in 109 cases (9.2%) were the most common tumors, respectively. Salivary gland tumors were more common in males, and the participants’ mean age was 42.86 ± 16.5 years. The most common site was parotid and minor salivary glands, with 937 (79.4%) and 137 (12%) cases, respectively. Conclusions: In this study, the most common benign tumor was pleomorphic adenoma in the parotid gland, and the most common malignant tumor was adenoid cystic carcinoma in the major salivary glands. Furthermore, benign tumors were more frequent than malignant tumors.

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Activity of hydrolytic enzyme in the poultry of different species

Scientific Messenger of LNU of Veterinary Medicine and Biotechnology ◽

10.32718/nvlvet8918 ◽

2018 ◽

Vol 20 (89) ◽

pp. 95-99

Author(s):

B. Ya. Kyryliv ◽

A. V. Hunchak ◽

О. М. Stefanyshyn

Keyword(s):

Digestive System ◽

Lipolytic Activity ◽

Physiological State ◽

Hydrolytic Enzyme ◽

Hydrolytic Enzymes ◽

The Body ◽

Free Access ◽

Critical Periods ◽

Metabolic Processes ◽

Organ Tissue

In the processes of digestion and assimilation of nutrients of feed in the body a special place belongs to the digestive system. Hydrolysis of nutrients in the gastrointestinal tract of farm poultry is closely linked to its physiological state, the intensity of metabolic processes in the body and its productivity. However, there are no significant differences in the course and regulation of digestive functions between individual poultry species. At the same time, for different types of poultry, certain distinctive patterns of the course of digestive processes and, in particular, the activity of hydrolytic enzymes, due to the peculiarities of the structure and functioning of the digestive system, are characteristic. In the article is given a fragment of complex systemic researches, which is concerning the proteolytic, amylolytic and lipolytic activity of enzymes in tissues of the organs of the digestive canal (mucous membrane of the glandular and duodenum, pancreas, liver) of the quail breed “Pharaoh”, as well as chicken egg productivity direction cross “Hayseks Brown” and the Beijing Broiler Duck Cross STAR 53 (heavy) selection of the French firm “GRIMAUD FRERES SELECTION” during the critical periods of their growth and development. Namely, in the period of adaptation of the organism after hatching (day-old chicks of all species), complete resorption of residual yolk (7-day quail and 6-day chickens and ducks) and puberty (120-day chickens, 42-day quails, 180-daily ducks) All poultry was kept in poultry farms and received balanced full-fodder feeds, taking into account its species, age and physiological condition. The technology of keeping quails and chickens in cellular batteries, and ducks – on the mesh floor, with free access to the feed and water. It was established, that the nature of changes in the activity of hydrolytic enzymes had organ-tissue and species specificity. This is due not only to the particularities of digestion in quails, chickens and ducks, but also the energy value of rations used in feeding each type of farm poultry, which significantly affects metabolic processes in the body.

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Route of a Multipartite Nanovirus across the Body of Its Aphid Vector

Journal of Virology ◽

10.1128/jvi.01998-19 ◽

2020 ◽

Vol 94 (9) ◽

Cited By ~ 6

Author(s):

Jérémy Di Mattia ◽

Marie-Stéphanie Vernerey ◽

Michel Yvon ◽

Elodie Pirolles ◽

Mathilde Villegas ◽

...

Keyword(s):

Salivary Gland ◽

Salivary Glands ◽

Plant Viruses ◽

The Body ◽

Insect Vector ◽

Vector Transmission ◽

Aphid Vector ◽

Vector Interaction ◽

Salivary Gland Cells ◽

Mode Of Transmission

ABSTRACT Vector transmission plays a primary role in the life cycle of viruses, and insects are the most common vectors. An important mode of vector transmission, reported only for plant viruses, is circulative nonpropagative transmission whereby the virus cycles within the body of its insect vector, from gut to salivary glands and saliva, without replicating. This mode of transmission has been extensively studied in the viral families Luteoviridae and Geminiviridae and is also reported for Nanoviridae. The biology of viruses within these three families is different, and whether the viruses have evolved similar molecular/cellular virus-vector interactions is unclear. In particular, nanoviruses have a multipartite genome organization, and how the distinct genome segments encapsidated individually transit through the insect body is unknown. Here, using a combination of fluorescent in situ hybridization and immunofluorescence, we monitor distinct proteins and genome segments of the nanovirus Faba bean necrotic stunt virus (FBNSV) during transcytosis through the gut and salivary gland cells of its aphid vector Acyrthosiphon pisum. FBNSV specifically transits through cells of the anterior midgut and principal salivary gland cells, a route similar to that of geminiviruses but distinct from that of luteoviruses. Our results further demonstrate that a large number of virus particles enter every single susceptible cell so that distinct genome segments always remain together. Finally, we confirm that the success of nanovirus-vector interaction depends on a nonstructural helper component, the viral protein nuclear shuttle protein (NSP), which is shown to be mandatory for viral accumulation within gut cells. IMPORTANCE An intriguing mode of vector transmission described only for plant viruses is circulative nonpropagative transmission, whereby the virus passes through the gut and salivary glands of the insect vector without replicating. Three plant virus families are transmitted this way, but details of the molecular/cellular mechanisms of the virus-vector interaction are missing. This is striking for nanoviruses that are believed to interact with aphid vectors in ways similar to those of luteoviruses or geminiviruses but for which empirical evidence is scarce. We here confirm that nanoviruses follow a within-vector route similar to that of geminiviruses but distinct from that of luteoviruses. We show that they produce a nonstructural protein mandatory for viral entry into gut cells, a unique phenomenon for this mode of transmission. Finally, noting that nanoviruses are multipartite viruses, we demonstrate that a large number of viral particles penetrate susceptible cells of the vector, allowing distinct genome segments to remain together.

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MULTI-MODALITY IMAGING OF SALIVARY GLAND TUMORS

10.36106/ijsr/1704364 ◽

2021 ◽

pp. 39-41

Author(s):

Yashvant Singh ◽

Namrita Sachdev ◽

Akhila Prasad ◽

Rushil Jain ◽

Dinesh Sethi

Keyword(s):

Salivary Gland ◽

Salivary Glands ◽

Cell Cancer ◽

Myoepithelial Cells ◽

The Body ◽

Salivary Gland Tumors ◽

Upper Aerodigestive Tract ◽

Cross Sectional ◽

Cross Sectional Imaging

Background: Imaging of salivary gland tumors is a challenge for the radiologist due to varied histological features and overlapping clinical presentation.The salivary glands have a glandular structure with tubules, secretory acini and myoepithelial cells to produce and secrete saliva. They are divided into two types: major and minor. Parotid, submandibular, and sublingual glands are the major paired salivary glands of the body. Multiple small minor salivary glands are distributed in the upper aerodigestive tract including PNS & parapharyngeal spaces. Objective: This study evaluates the role of different modalities used to assess salivary gland tumors. Results: 50 patients presenting with suspected salivary gland masses were evaluated. 22 males and 28 females were assessed with age ranging from 15 to 66 years (mean age of 52 years). 27 cases were of pleomorphic adenoma, 10 warthin tumors, 2 intraductal papilloma,1 lipoma, 1 oncocytoma,1 intra parotid paraganglioma, 2 hemangioma, 3 muco-epidermoid carcinoma, 2 adeno cystic cancer and 1 acinic cell cancer of salivary gland. 90% of patients (45 out of 50) presented with swelling / lump. 26% of patients had pain /discomfort and 4% of patients (2 out of 50) had facial nerve palsy. Conclusion: The conventional radiological evaluation was carried out using Xray and ultrasound with USG as rst line of investigation.. Cross sectional imaging with CT and MRI is useful in assessing for local extension , invasion of neighbouring structures as well as lymph nodal and systemic metastasis.MRI is superior to CT in assesing for extent and perineural spread.

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Common immunophenotypic features of submandibular salivary glands and thymus in rats

Srpski arhiv za celokupno lekarstvo ◽

10.2298/sarh1206270d ◽

2012 ◽

Vol 140 (5-6) ◽

pp. 270-277

Author(s):

Ivan Dozic ◽

Tatjana Todorovic ◽

Miodrag Colic

Keyword(s):

Salivary Gland ◽

Epithelial Cells ◽

Salivary Glands ◽

Endocrine System ◽

Immunohistochemical Analysis ◽

The Body ◽

Thymic Epithelial Cells ◽

Submandibular Salivary Gland ◽

Phenotypic Similarity ◽

Submandibular Salivary Glands

Introduction. Submandibular salivary gland is a part of the neuro-immune-endocrine system. It contains biological factors which regulate a number of functions in the body including the modulation of thymus function. Objective. The aim of the study was to investigate immunophenotypic characteristics of submandibular salivary glands of rats during ontogenesis, using the panels of monoclonal antibodies and to compare with the phenotypic characteristics of epithelial components of the thymus. Methods. Submandibular salivary glands and thymus were obtained from 1, 30 and 60 days old male AO (Albino, Oxford) rats. Streptavidin-biotin peroxidase method was used for staining. Results. Immunohistochemical analysis of rat submandibular salivary glands showed phenotypic heterogeneity of particular components of this gland during the postnatal development. We demonstrated that rat submandibular salivary glands share common antigens with rat thymic epithelial cells, but the observed phenotypic similarity between the individual regions was considered much more significant. Our data showed that the phenotypic similarity between duct epithelial cells and subcapsular epithelial cells and most medullary cells, whereas cortical epithelial cells are phenotypically similar to acinar cells. Conclusion. This immunohistological study showed phenotypic complexity of the submandibular salivary gland and similarity to the thymus that opens new perspectives in studying phenotypic similarities between this gland and lymphatic organs.

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Electrical potentials of the parotid salivary gland recorded from the body surface in cats

Bulletin of Experimental Biology and Medicine ◽

10.1007/bf00801801 ◽

1978 ◽

Vol 86 (6) ◽

pp. 1563-1565

Author(s):

M. A. Sobakin ◽

V. P. Makhnev

Keyword(s):

Salivary Gland ◽

Body Surface ◽

The Body ◽

Electrical Potentials ◽

Parotid Salivary Gland

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February 9 — Dentist Day in Russia

Spravočnik vrača obŝej praktiki (Journal of Family Medicine) ◽

10.33920/med-10-2002-10 ◽

2020 ◽

pp. 78-81

Author(s):

Oksana Rybachok

Keyword(s):

Early Childhood ◽

Oral Cavity ◽

Salivary Glands ◽

Spiritual Development ◽

The Body ◽

Mechanical Processing ◽

Normal Functioning ◽

Digestion Process ◽

Quality Of Food

«Man is what he eats,» these words belong to the great Pythagoras. He meant by these words the connection of the origin of consumed food with the spiritual development of man. In fact, a lot depends on the nature of nutrition, the quality of food and, of course, on the degree of its perception by the body. Digestion process begins not in the stomach, but directly in the oral cavity as a result of mechanical processing of products with teeth and under the influence of the secretion of the salivary glands. That is why healthy teeth are the key to the normal functioning of the whole organism — people should start taking care of their teeth from the early childhood and dentists, who are far from being beloved by everybody and are often carelessly evaded, are called upon to help keep the teeth healthy.

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