Hippotherapy as a comprehensive corrective-developing method for rehabilitation of children with ICP

2021 ◽  
pp. 66-75
Author(s):  
Helen Larina ◽  
Ya. S. Galant ◽  
P. R. Dorozhukova
Keyword(s):  
Developing Method

Pengembangan Bahan Ajar Mata Pelajaran Sosiologi Siswa Madrasah Aliyah

2017 ◽  
Vol 2 (1) ◽  
pp. 51
Author(s):  
Wagimin Wagimin
Keyword(s):  
High School ◽  
Small Group ◽  
Field Test ◽  
Instructional Material ◽  
Material Design ◽  
Teaching Sociology ◽  
One To One ◽  
Teaching Learning ◽  
Developing Method ◽  
Test Result

Abstract Penelitian ini bertujuan untuk mengembangkan perangkat materi pembelajaran untuk pengajaran sosiologi guna memotivasi siswa. Penelitian ini menggunakan metode penelitian dan pengembangan guna menformulasi produk dan mengukur efektifitasnya melalui validasi dan pengujian ahli di bidangnya. Ada tiga tipe test yang digunakan yaitu, one to one, small group, dan field test yang menunjukkan bahwa desain materi tersebut efektif. Setelah melalui revisi, desain meteri pembelajaran Sosiologi dianggap bermanfaat dan dapat digunakan dalam proses belajar mengajar Kata Kunci: Perangkat pembelajaran, mata pelajaran Sosiologi, siswa Madrasah Aliyah Abstract [Tittle: The Development of Sosiology Instructional Material for The Students fo Islamic Senior High School] . The research aims at developing a set of instructional material for teaching Sociology in order to motivate the students. The researcher employed a research and developing method to formulate a product and to measure its effectiveness through validation and trial-out by the experts of content-material and material-design. There were three types of trial to test the design; one to one, small group, and field test. Based on the test result, it was found that students in average can achieve 84% of overall score which indicate that the designed material is effective. After being revised several times in each stage, the design of instructional material for Sociology subject is considered as beneficial and able to be used in the teaching learning process

scholarly journals Development of a Selection Method for Discovering Irreversible (Covalent) Binders from a DNA-Encoded Library

2018 ◽  
Vol 24 (2) ◽  
pp. 169-174 ◽  
Author(s):  
Zhengrong Zhu ◽  
LaShadric C. Grady ◽  
Yun Ding ◽  
Kenneth E. Lind ◽  
Christopher P. Davie ◽  
...  
Keyword(s):  
Magnetic Beads ◽  
Chemical Probes ◽  
Lead Discovery ◽  
3C Protease ◽  
Discovery Research ◽  
Drug Discovery Research ◽  
Affinity Resin ◽  
Covalent Ligands ◽  
Developing Method ◽  
Unique Mechanism

DNA-encoded libraries (DELs) have been broadly applied to identify chemical probes for target validation and lead discovery. To date, the main application of the DEL platform has been the identification of reversible ligands using multiple rounds of affinity selection. Irreversible (covalent) inhibition offers a unique mechanism of action for drug discovery research. In this study, we report a developing method of identifying irreversible (covalent) ligands from DELs. The new method was validated by using 3C protease (3CP) and on-DNA irreversible tool compounds (rupintrivir derivatives) spiked into a library at the same concentration as individual members of that library. After affinity selections against 3CP, the irreversible tool compounds were specifically enriched compared with the library members. In addition, we compared two immobilization methods and concluded that microscale columns packed with the appropriate affinity resin gave higher tool compound recovery than magnetic beads.

Development of Parametric CAD System Based on Pro / Toolkit and Database Technology

2011 ◽  
Vol 55-57 ◽  
pp. 2235-2241 ◽  
Author(s):  
Hui Lan Zhou
Keyword(s):  
User Interface ◽  
Dynamic Link Library ◽  
Cad System ◽  
Mechanical Part ◽  
Data Object ◽  
Standard Part Library ◽  
Database Technology ◽  
Parametric Cad ◽  
Developing Method ◽  
Dynamic Link

With Pro/Toolkit of Pro/E and ADO(ActiveX Data Object) database technology, part parametric CAD system is developed and an successful instance is introduced in the paper. In the CAD system, interface between Pro/E and VC++6.0 is created correctly using Pro / Toolkit and user interface for part parametric designing can be achieved by means of dll( dll dynamic link) library built in VC++6.0 .Meanwhile ADO database is applied in the CAD system to manage all part parameters and thus part revising and updating can be realized quickly. The developing method in the CAD system not only is applicable to typical mechanical part designing but also be helpful to establishing standard part library.

scholarly journals DEVELOPMENT OF FLOW INJECTION METHOD FOR ONLINE DETERMINATION OF THIOCYANATE BASED ON OXIDATION BY PERMANGANATE

2010 ◽  
Vol 10 (2) ◽  
pp. 167-171 ◽  
Author(s):  
Hermin Sulistyarti ◽  
Spas D. Kolev ◽  
Stephanie Lim
Keyword(s):  
Detection Limit ◽  
Thyroid Gland ◽  
Flow Injection ◽  
Hydrogen Cyanide ◽  
Figures Of Merit ◽  
Sample Throughput ◽  
Teflon Membrane ◽  
Developing Method ◽  
Analytical Figures Of Merit

The importance of developing method for thiocyanate becomes obvious, because thiocyanate can inhibit iodine uptake of thyroid gland leading to mumps disease. In this work, thiocyanate is oxidized by permanganate in the acid donor stream to cyanide, which is directly converted to hydrogen cyanide. Then, hydrogen cyanide diffuses through a Teflon membrane into acceptor stream containing nickel(II) in ammoniacal buffer to form tetracyanonickelate(II) which is detected spectrophotometrically at 267 nm. Analytical figures of merit were linear up to 50 mg L-1 for thiocyanate, with RSD of 1.34%, and detection limit of 0.07 mg L-1, respectively. Interfering anions were eliminated under stoichiometric amount of permanganate and sample throughput was 20 h-1. The method was validated for determining thiocyanate samples from synthetic and gold process waters with satisfactory results.   Keywords: Thiocyanate, flow injection, permanganate, spectrophotometry

scholarly journals Confirmation of aflatoxin in fish and shrimp by LC/MS-MS (ZEVO TQD)

2020 ◽  
Vol 4 (1) ◽  
pp. 14-21
Author(s):  
Mohammed Anwar Parvez ◽  
Md Barkatul Alam ◽  
Md Manik Mia
Keyword(s):  
Prolonged Exposure ◽  
Raw Materials ◽  
Human Consumption ◽  
Detection Capability ◽  
Species Sensitivity ◽  
Chronic Effects ◽  
Agricultural Contaminants ◽  
High Humidity Environment ◽  
Acute And Chronic Effects ◽  
Developing Method

Mycotoxins are agricultural contaminants of fungal origin occurring at all latitudes worldwide and being characterized by acute and chronic effects on human health and animal wellness, depending on the species sensitivity. Various types of crops like maize, wheat, soybeans etc are used as raw materials for preparing feed of fish and shrimp. They are particularly susceptible to infection by Aspergillus following prolonged exposure to a high humidity environment. For this reason, the fish and shrimp samples should be tested for identifying and quantifying mycotoxin. The major mycotoxins of food concern are aflatoxin (B1, B2, G1, G2) for its toxicity. This paper focus on the confirmation of aflatoxin in fish and shrimp by developing method and validated it by LC/MS-MS (ZEVO TQD) which is important for ensuring the safety of fishery product for human consumption. The monitored MRM transitions for B1, B2, G1, G2 were m/z 31357 and m/z 31371, m/z 31888 and m/z 318256, m/z 328.75242.99 and m/z 328.75199.9, m/z 330.3488 and m/z 330.34106 respectively. Limit of decision (CCα) for B1, B2, G1, G2 were 0.59 μg/kg, 0.70 μg/kg, 0.68 μg/kg, 0.83 μg/kg respectively and detection capability (CCβ) for B1, B2, G1, G2 were 1.01μg/kg, 1.19 μg/kg, 1.15 μg/kg, 1.40 μg/kg respectively. Asian Australas. J. Food Saf. Secur. 2020, 4 (1), 14-21

Computer-Aided Development of Shape Memory Actuators as an Approach Towards a Standardized Developing Method

2011 ◽  
Author(s):  
Horst Meier ◽  
Alexander Czechowicz
Keyword(s):  
Numerical Model ◽  
Shape Memory ◽  
Smart Materials ◽  
Fatigue Behavior ◽  
Design Tool ◽  
Thermally Activated ◽  
Shape Memory Actuators ◽  
Computer Aided ◽  
Actual Shape ◽  
Developing Method

Shape memory alloys (SMA) are thermally activated smart materials. Due to their ability to change into a previously imprinted actual shape through the means of thermal activation, they are suitable as actuators for mechatronical systems. Despite of the advantages shape memory alloy actuators provide (lightweight-actuators, lower costs…etc.) these elements are only seldom integrated by engineers into mechatronical systems. The reason for this phenomenon is the insufficiently described dynamic behavior, especially at different boundary conditions. Also the lack of empirical data (like fatigue behavior and thermal balances) is a reason why development projects with shape memory actuators lead often to failures. Therefore a need of developing methods, standardized testings of empirical properties and computer aided actuator development systems is motivated. Based on an analysis of energy fluxes into and out of the actuator, a numerical model, implemented in MATLAB/SIMULINK is presented. The numerical model includes also a configuration and design tool which allows simulating different solutions to a problem. Additionally, this paper describes a development method for SMA which is fitted to uniqueness of these smart materials. In conclusion, this paper compares the conventional developing process to the presented method applying a mechatronical SMA-device.

Development of Numerical Simulation for Jet Breakup Behavior in Complicated Structure of BWR Lower Plenum: 1 — Preliminary Analysis of Jet Breakup Behavior in Complicated Structure by TPFIT

2013 ◽  
Author(s):  
Takayuki Suzuki ◽  
Hiroyuki Yoshida ◽  
Fumihisa Nagase ◽  
Yutaka Abe ◽  
Akiko Kaneko
Keyword(s):  
High Speed ◽  
Measured Data ◽  
Severe Accident ◽  
Interface Tracking ◽  
Phase Flow ◽  
Complicated Structure ◽  
Support Plate ◽  
Jet Breakup ◽  
Multi Phase ◽  
Developing Method

In order to improve the safety of Boiling Water Reactor (BWR), it is required to know the behavior of the plant when an accident occurred as can be seen at Fukushima Daiichi nuclear power plant accident. Especially, it is important to estimate the behavior of molten core jet in the lower part of the containment vessel at severe accident. In the BWR lower plenum, the flow characteristics of molten core jet are affected by many complicated structures, such as control rod guide tubes, instrument guide tubes and core support plate. However, it is difficult to evaluate these effects on molten core jet experimentally. Therefore, we considered that multi-phase computational fluid dynamics approach is the best way to estimate the effects on molten core jet by complicated structure. The objective of this study is to develop the evaluation method for the flow characteristic of molten core jet including the effects of the complicated structures in the lower plenum. So we are developing a simulation method to estimate the behavior of molten core jet falling down through the core support plate to the lower plenum of the BWR. The method has been developed based on interface tracking method code TPFIT (Two Phase Flow simulation code with Interface Tracking). To verify and validate the applicability of the developed method in detail, it is necessary to obtain the experimental data that can be compared with detailed numerical results by the TPFIT. Thus, in this study, we are carrying out experimental works by use of multi-phase flow visualization technique. In the experiments, time series of interface shapes are observed by high speed camera and velocity profiles in/out of the jet will be measured by the PIV method. In this paper, the outline of the developing method based on the TPFIT was explained. And, the developing method was applied to preliminary experiment with/without modeled complicated structures. As the results, predicted interface shapes were almost agreed with measured data. However, predicted falling down velocity of the jet was lower than measured data. We considered causes of this underestimation and improved the method and simulation conditions to resolve this problem.

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