Review on Standardization Parameters of Churna

Ayurved has a long and strong heritage use of Polyherbal drugs and formulations to treat various diseases. Standardization of Ayurvedic formulations is an important step for the establishment of a consistent biological activity, a consistent chemical profile or simply a quality assurance program for production and manufacturing of herbal drugs. It is a burning topic in Ayurvedic drug industry nowadays. Tremendous work is going on for standardization of Ayurvedic drugs to prove its reproducibility, compatibility and safety on modern parameters. Concept of churna is well established in Ayurvedic pharmaceutics for therapeutic purposes as well as for production of other formulations. There is sound description of its various method of preparation along with shelf life period in Ayurveda. Implication of latest analytical techniques is the demand of time to standardize different churna. Plant material may vary in physiochemical content and therefore in its therapeutic effect; according to different places of collection, with different times in a year for collection, with collection at the same time and places but in different years and with a particular medicinal plant. Adding to this variability is the fact that in herbal medicine several plants may be used together in the same preparation. It is very important that a system of standardization is established for every medicine in the market because the scope for variation in different batches of medicine is enormous. This means that there should be a quality control test for the entire preparation to ensure quality of the product.

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Evaluation of standardization parameter of polyherbal digestive “churna”

Indian Journal of Pharmaceutical and Biological Research ◽

10.30750/ijpbr.5.2.8 ◽

2017 ◽

Vol 5 (02) ◽

pp. 39-44

Author(s):

Abhishek Bhardwaj ◽

K. K. Jha ◽

A. Panka ◽

Anuj Agarwal ◽

Bhuvnesh Singh ◽

...

Keyword(s):

Quality Control ◽

Quality Assurance ◽

Fine Powder ◽

Routine Analysis ◽

Control Test ◽

One Year ◽

Evaluation Parameters ◽

Quality Control Test

The development in these traditional systems of medicine leads to maintain proper quality of the product. India is rich in its flora and fauna. These plants are being used for curing many diseases as such in raw condition rather the being prepared as formulation. Churana is defined as a fine powder of drug or drugs in Ayurvedic system of medicine. Drugs mentioned in patha, are cleaned properly, dried thoroughly, pulverised and then sieved. The churana is free flowing and retains its potency for one year, if preserved in air tight containers. Churna formulations are similar to powder formulations in Allopathic system of medicine. In recent days churna is formulated into tablets in order to fix the dose easily. The churana was evaluated depending on various evaluation parameters and from the results obtained it was found to be within the standards. These preliminary tests can be prescribed as standards to fix the quality control test the churana and can be used in routine analysis of the same. The can also be used to perform quality control and quality assurance in the laboratory.

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The real concept of substitution in Ayurveda literature and adulteration the misleading concept of modern era

Journal of Ayurveda and Integrated Medical Sciences (JAIMS) ◽

10.21760/jaims.v3i3.12890 ◽

2018 ◽

Vol 3 (3) ◽

Author(s):

Ashashri Shinde ◽

Pankaj Gupta ◽

Sudipt Rath

Keyword(s):

Medicinal Plant ◽

Plant Material ◽

Genetic Parameters ◽

Herbal Drugs ◽

Material Identification ◽

The Real ◽

Physical Chemical ◽

Unfair Trade ◽

Modern Era

A quality drug is central to the success of any therapeutic plan. The quality of drug is determined right from the collection to delivery to the patients. The commonest problem involving the medicinal plant stating materials is intentional or unintentional substitution and adulteration owing to multiple reasons like unavailability, higher costs, unfair trade etc. This trend was also present in the olden days, as evident from the concept of substitute drugs (Pratinidhi Dravya) as available in Yogratanakara, Bhavaprakasha and Bhaishajyaratnawali. Therefore, Charka and later Acharyas also have dealt with authentication and standardization of herbal drugs and formulations in detail by using four Pramanas (tools of knowledge) Ch.Vi.8/87. Nowadays the concept of substitution is entirely converted into intentional and unintentional malpractices of adulteration. The established authenticity parameters for plant material identification and standardization like organoleptic, physical, chemical and genetic parameters are relatively inaccessible for routine use. Not withstanding the accuracy and usefulness of these lab parameters and delay in the development of easy to perform parameters for reasonable drug authentication. These adulteration malpractices spoils the market of herbal industries. In this article we discuss about concept of substitution in ancient Ayurveda and at present intentional and unintentional adulteration practices.

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DRUG REGULATORY PROCEDURES IN TANZANIA: A GLIMPSE

International Journal of Drug Regulatory Affairs ◽

10.22270/ijdra.v3i2.12 ◽

2015 ◽

Vol 3 (2) ◽

pp. 1-7 ◽

Cited By ~ 1

Author(s):

Achin Jain ◽

M P Venkatesh M P ◽

Pramod T.M. Kumar

Keyword(s):

Quality Control ◽

Medical Devices ◽

Emerging Market ◽

Well Being ◽

New Drugs ◽

Regulatory Body ◽

Herbal Drugs ◽

Drug Products ◽

Set Up

In Tanzania, Tanzania Food and Drugs Authority (TFDA), is a regulatory body responsible for controlling the quality,safety and effectiveness of food, drugs, herbal drugs, cosmetics and medical devices. The Authority has been ensuringsafety, efficacy and quality of medicines by quality control tests; in addition to other quality assessment mechanisms.The guidelines laid by TFDA have also emanated from commitment to democracy and gives strong emphasis to thefulfilment of the needs of the less privileged rural population.Tanzania is an emerging market; the pharmaceutical market is valued at over US$250 million, and is growing at anannual rate of around 16.5% and is expected to reach approximately US$550 billion in 2020. Currently, the market ishighly dependent on imports, which account for around 75% of the total pharmaceutical market.The procedures and approval requirements of new drugs, variations, import, export and disposal have been set up bythe TFDA, which help in maintaining quality of the drug products that are imported as well being produced locally

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A quality-control test for predatory journals

Nature ◽

10.1038/d41586-018-00403-z ◽

2018 ◽

Vol 553 (7687) ◽

pp. 155-155 ◽

Cited By ~ 4

Author(s):

Steven N. Goodman

Keyword(s):

Quality Control ◽

Control Test ◽

Predatory Journals ◽

Quality Control Test

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Review on Standardization of Ayurvedic Medicine

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i57a33986 ◽

2021 ◽

pp. 194-199

Author(s):

Janmejay Pant ◽

. Ripudhaman

Keyword(s):

Quality Control ◽

Raw Materials ◽

Dosage Forms ◽

Classical Literature ◽

Scientific Methods ◽

Ayurvedic Drugs ◽

Drug Manufacturing ◽

And Storage ◽

Current Guidelines

Standardization in Ayurvedic formulations ensures the establishment of standards for the quality and purity of raw materials, quality control during the drug manufacturing process, production of a good quality finished product, storage and distribution to maintain the quality of the final product. It is an essential tool for establishing quality control methods for Ayurvedic drugs. In Ayurveda, standardization has been well defined and documented in the classical and contemporary texts. Still, these have been written with an individualistic intent and not for industrial or commercial purposes. Careful contemplation of the classical literature of Ayurveda was done, the current guidelines of WHO on standardization of herbal drugs, latest researches on the same via the internet were explored and examined in the purview of the newest standardization procedures. In this article, an attempt has been made to bring to light the classical references related to standardization, the milestones in this on-going pursuit have been exhibited, with the use of the latest scientific methods being incorporated for a standardized Ayurvedic drug. It can be concluded from the review that standardization in Ayurveda is an on-going process where one needs to be strictly vigilant about the new scientific methods to study the fine chemical procedures and the intermediate compounds formed, but at the same time be aware of the classical. Ayurvedic methods concepts of the procedure. Asava-arista's medicinal characteristics of Ayurvedic classical dosage forms, liquid dosage forms based on self-generated alcohol with faster absorption, long shelf life, and increased market conformity have led to a continuous rise in demand. New fermentation methods and packaging innovations tend to have been embraced by many Ayurvedic processing units. The importance of standardization of such goods is underlined by these advances in manufacturing, distribution and storage. Therefore, it is of concern to examine the latest manufacturing situation and the standardization of the dosage type regarding the procedure and the consistency and effectiveness of the finished product. In addition to the effort to include criteria of consistency and standardization, the study consists of an overview and deliberates on the importance of improvements made to the conventional preparation processes, ingredients and material used in the process and the potential impact on its efficacy.

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A rapid quality control test to foster the development of the sterile insect technique against Anopheles arabiensis

Malaria Journal ◽

10.1186/s12936-020-3125-z ◽

2020 ◽

Vol 19 (1) ◽

Cited By ~ 1

Author(s):

Nicole J. Culbert ◽

Nanwintoum Séverin Bimbilé Somda ◽

Maiga Hamidou ◽

Dieudonné Diloma Soma ◽

Silvana Caravantes ◽

...

Keyword(s):

Quality Control ◽

Sterile Insect Technique ◽

Anopheles Arabiensis ◽

Control Test ◽

Quality Control Test

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The Use of SEM and Light Microscopy for the Characterization of Hypericum foliosum Aerial Part as a Medicinal Plant

Microscopy and Microanalysis ◽

10.1017/s1431927608089551 ◽

2008 ◽

Vol 14 (S3) ◽

pp. 107-108

Author(s):

R. Serrano ◽

P. Ferreira ◽

E.T. Gomes ◽

O. Silva

Keyword(s):

Quality Control ◽

Medicinal Plant ◽

Light Microscopy ◽

Plant Material ◽

Aerial Part ◽

Chemical Characterization ◽

Correct Identification ◽

Herbal Drugs ◽

Herbal Drug

The first step in quality control of herbal drugs is ensuring the correct identification of the plant intended for use. The required analytical procedures (macroscopic characterization of the entire or fragmentized material, microscopic characterization after pulverization of the plant material and chemical characterization), are usually described on quality monographs reported in authoritarian texts such as the European 6th Pharmacopoeia. Further information related to the name of the each herbal drug, the herbal drug definition, purity tests and assay are also provided.

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