scholarly journals The Use of SEM and Light Microscopy for the Characterization of Hypericum foliosum Aerial Part as a Medicinal Plant

2008 ◽  
Vol 14 (S3) ◽  
pp. 107-108
Author(s):  
R. Serrano ◽  
P. Ferreira ◽  
E.T. Gomes ◽  
O. Silva

The first step in quality control of herbal drugs is ensuring the correct identification of the plant intended for use. The required analytical procedures (macroscopic characterization of the entire or fragmentized material, microscopic characterization after pulverization of the plant material and chemical characterization), are usually described on quality monographs reported in authoritarian texts such as the European 6th Pharmacopoeia. Further information related to the name of the each herbal drug, the herbal drug definition, purity tests and assay are also provided.

Author(s):  
Ashashri Shinde ◽  
Pankaj Gupta ◽  
Sudipt Rath

A quality drug is central to the success of any therapeutic plan. The quality of drug is determined right from the collection to delivery to the patients. The commonest problem involving the medicinal plant stating materials is intentional or unintentional substitution and adulteration owing to multiple reasons like unavailability, higher costs, unfair trade etc. This trend was also present in the olden days, as evident from the concept of substitute drugs (Pratinidhi Dravya) as available in Yogratanakara, Bhavaprakasha and Bhaishajyaratnawali. Therefore, Charka and later Acharyas also have dealt with authentication and standardization of herbal drugs and formulations in detail by using four Pramanas (tools of knowledge) Ch.Vi.8/87. Nowadays the concept of substitution is entirely converted into intentional and unintentional malpractices of adulteration. The established authenticity parameters for plant material identification and standardization like organoleptic, physical, chemical and genetic parameters are relatively inaccessible for routine use. Not withstanding the accuracy and usefulness of these lab parameters and delay in the development of easy to perform parameters for reasonable drug authentication. These adulteration malpractices spoils the market of herbal industries. In this article we discuss about concept of substitution in ancient Ayurveda and at present intentional and unintentional adulteration practices.


2011 ◽  
Vol 2011 ◽  
pp. 1-9 ◽  
Author(s):  
V. F. Furletti ◽  
I. P. Teixeira ◽  
G. Obando-Pereda ◽  
R. C. Mardegan ◽  
A. Sartoratto ◽  
...  

The efficacy of extracts and essential oils fromAllium tuberosum, Coriandrum sativum, Cymbopogon martini, Cymbopogon winterianus,andSantolina chamaecyparissuswas evaluated againstCandidaspp. isolates from the oral cavity of patients with periodontal disease. The most active oil was fractionated and tested againstC. albicansbiofilm formation. The oils were obtained by water-distillation and the extracts were prepared with macerated dried plant material. The Minimal Inhibitory Concentration—MIC was determined by the microdilution method. Chemical characterization of oil constituents was performed using Gas Chromatography and Mass Spectrometry (GC-MS). C. sativum activity oil upon cell and biofilm morphology was evaluated by Scanning Electron Microscopy (SEM). The best activities against planktonicCandidaspp. were observed for the essential oil and the grouped F8–10fractions fromC. sativum. The crude oil also affected the biofilm formation inC. albicanscausing a decrease in the biofilm growth. Chemical analysis of the F8–10fractions detected as major active compounds, 2-hexen-1-ol, 3-hexen-1-ol and cyclodecane. Standards of these compounds tested grouped provided a stronger activity than the oil suggesting a synergistic action from the major oil constituents. The activity ofC. sativumoil demonstrates its potential for a new natural antifungal formulation.


CERNE ◽  
2016 ◽  
Vol 22 (3) ◽  
pp. 261-270 ◽  
Author(s):  
Claúdia Luizon Dias Leme

ABSTRACT Different medicinal plant species can be sold under the same common name. Considering the importance of the correct identification, this study aims to separate, using wood anatomy, seven species popularly known as pau-para-tudo. The results show that Drimys brasiliensis is separated from the others by the presence of tracheids. Capsicodendron dinisii hhas scalariform perforation plates and oil cells associated with the axial parenchyma. Axial parenchyma paratracheal vasicentric and in marginal bands beyond the rays' width, can separate Osteophoeum platyspermum from Simaba cedron. Handroanthus serratifolius has the unique presence of the axial unilateral paratracheal parenchyma and storied cell elements (parenchyma, fibers and vessel elements). Rauvolfia sellowii and Leptolobium dasycarpum can be separated by the number of square/upright marginal ray cells, greater in Rauvolfia sellowii. Thus, this work shows that wood anatomy is a valuable tool for species separation, helps with the identification and consequently is important for the quality control of plant product.


Planta Medica ◽  
2018 ◽  
Vol 84 (06/07) ◽  
pp. 465-474 ◽  
Author(s):  
Débora Frommenwiler ◽  
Jonghwan Kim ◽  
Chang-Soo Yook ◽  
Thi Tran ◽  
Salvador Cañigueral ◽  
...  

AbstractThe quality of herbal drugs is usually controlled using several tests recommended in a monograph. HPTLC is the method of choice for identification in many pharmacopoeias. If combined with a suitable reference material for comparison, HPTLC can provide information beyond identification and thus may simplify quality control. This paper describes, as a proof of concept, how HPTLC can be applied to define specifications for an herbal reference material and to control the quality of an herbal drug according to these specifications. Based on multiple batches of cultivated Angelica gigas root, a specific HPTLC method for identification was optimized. This method can distinguish 27 related species. It also can detect the presence of mixtures of A. gigas with two other Angelica species traded as “Dang gui” and is suitable as well for quantitative assessment of samples in a test for minimum content of the sum of decursin and decursinol angelate. The new concept of “comprehensive HPTLC fingerprinting” is proposed: HPTLC fingerprints (images), which are used for identification, are converted into peak profiles and the intensities of selected zones are quantitatively compared to those of the corresponding zones of the reference material. Following a collaborative trial involving three laboratories in three countries, the method was applied to check the quality of further candidates for establishing an appropriate reference material. In conclusion, this case demonstrates that a single HPTLC analysis can provide information about identity, purity, and minimum content of markers of an herbal drug.


2009 ◽  
Vol 15 (S3) ◽  
pp. 11-12 ◽  
Author(s):  
C. Curica ◽  
R. Serrano ◽  
E. T. Gomes ◽  
O. Silva

AbstractFrangula azorica V. Grubow (Rhamnaceae), locally known as “sanguinho”, is an Azorean endemism inscribed on the IUCN Red List of Threatened Species. Morphological, chemical and biological studies on F. azorica are scarce, but preliminary studies on the bark of this species enable the identification of anthraquinone derivatives as major compounds of this plant part. This kind of compounds are present and responsible for the laxative activity of Frangulae cortex and Rhamni purshianae cortex, two well known herbal drugs of the Western Pharmacopoeias belonging to the same botanical familly (Rhamnaceae).


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Neelofar Majid ◽  
Saduf Nissar ◽  
Weekar Younus Raja ◽  
Irshad A. Nawchoo ◽  
Zulfikar Ali Bhat

Abstract Background Aralia cachemirica Decne. is an endemic and an important medicinal plant species of Kashmir Himalaya. Despite having immense medicinal importance, little information is available on the standardization parameters of the species. For this reason, present work was carried out for providing comprehensive report on the quality control and standardization parameters of A. cachemirica. In this connection, different parts (leaves, stem, and root) of the plant were examined. Methods like microscopy and macroscopy, physicochemical parameters, extractive values, and fluorescence analysis were used to establish pharmacognostical standards. Results The macroscopic, microscopy, and physicochemical parameters of different parts of A. cachemirica revealed various diagnostic characteristics in the species. Conclusion This is the first study providing complete pharmacognostic profile of A. cachemirica and hence will be useful for correct identification and authentication of the species for future studies.


2020 ◽  
Vol 23 (6) ◽  
pp. 1422-1427
Author(s):  
Said Gharby ◽  
Ali Asdadi ◽  
Mohamed Ibourki ◽  
Aicha Hamdouch ◽  
Tarik Ainane ◽  
...  

Author(s):  
Dipika R. Turankar ◽  
Sneha Kubde

Ayurved has a long and strong heritage use of  Polyherbal drugs and formulations to treat various diseases. Standardization of Ayurvedic formulations is an important step for the establishment of a consistent biological activity, a consistent chemical profile or simply a quality assurance program for production and manufacturing of herbal drugs. It is a burning topic in Ayurvedic drug industry nowadays. Tremendous work is going on for standardization of Ayurvedic drugs to prove its reproducibility, compatibility and safety on modern parameters.                    Concept of churna is well established in Ayurvedic pharmaceutics for therapeutic purposes as well as for production of other formulations. There is sound description of its various method of preparation along with shelf life period in Ayurveda. Implication of latest analytical techniques is the demand of time to standardize different churna. Plant material may vary in physiochemical content and therefore in its therapeutic effect; according to different places of collection, with different times in a year for collection, with collection at the same time and places but in different years and with a particular medicinal plant. Adding to this variability is the fact that in herbal medicine several plants may be used together in the same preparation. It is very important that a system of standardization is established for every medicine in the market because the scope for variation in different batches of medicine is enormous. This means that there should be a quality control test for the entire preparation to ensure quality of the product.


2012 ◽  
Vol 454 ◽  
pp. 55-58
Author(s):  
Lian Wei Yang ◽  
Rui Jie Wang ◽  
Guo Sheng Gai

Honghua has been demonstrated useful for promoting blood circulation and stopping pain. The physicochemical characterization of Honghua powders was greatly influenced by ultrafine pulverization. To study the physicochemical characterization of Honghua, the raw plant material of Honghua was ground to powders by high speed centrifugal sheering (HSCS) pulverizer. The micron powders were characterized by laser scattering granulometric analyzer and scanning electron microscope (SEM). Hydroxysafflor yellow A is one of active ingredients of Honghua, and its dissolution speed was determined to evaluate the chemical characterization of Honghua powder. The results showed that after ultrafine pulverization, dissolution speed of hydroxysafflor yellow A was increased by 28.6% compared with the normal powders


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