Critical Study Of Ischemic Heart Disease W.S.R. To Ayurvedokta Shatkriyakala

Author(s):  
Subhash Waghe ◽  
Sanjay P. Deshmukh ◽  
Pradnya P. Thakre

The death due to ischemic heart disease is increasing in Indian population at an alarming rate and accounts for around 15-20% of all deaths. The number of factors play role in the development of ischemic heart diseases but over consumption of oily fatty food and unhealthy lifestyle (mithya ahar vihar) with mental stress are the important basic factors enumerated by both the science. Shatkriya Kala is a unique pathological concept in Ayurveda developed with aim of treating the diseases at various stages of pathogesnesis. Ancient Ayurvedic acharyas had stated 6 such stages of therapeutic intervention with reference to six stages of pathogenesis namely sanchaya, prakopa, prasara, sthansanshraya, vyakti and bheda.. If disease is treated in early stages, it does not lead to complications. Hence, it is essential to apply the Ayurvedic concept of pathogenesis like ‘Shat Kriyakala’  to ischemic heart disease so as to study it from Ayurvedic pathological point of view and to evolve a strategy to deal with it, based on the Ayurvedokta principles of treatment particularly in terms of shatkriyakalas. The study of ischemic heart disease with reference to Shat Kriyakala, showed that the pathogenesis of ischemic heart disease can very well be arranged in Ayurvedokta  six stages of Shat Kriyakala and treatment could be framed as per different stages. With the help of modern investigations, these six stages could be confirmed.

Author(s):  
Subhash Waghe

Valvular heart diseases leads to definite death by various complications if not treated early. Although it may start as the simple throat infection but eventually it may affect the heart valves if not treated early. Shatkriya Kala is a unique pathological concept in Ayurveda developed with aim of treating the diseases at various stages of pathogenesis. Ancient Ayurvediac acharyas had stated 6 such stages of therapeutic intervention with reference to six stages of pathogenesis namely sanchaya, prakopa, prasara, sthansanshraya, vyakti and bheda.. If disease is treated in early stages, it does not lead to complications. There are vishahra a,d aamhar drugs in Ayurveda which could be potentially used to treat valvular affections. Hence, it is essential to apply the Ayurvedic concept of pathogenesis like ‘Shat Kriyakala’  to valvular heart disease so as to study it from Ayurvedic pathological point of view and to evolve a strategy to deal with it based on the Ayurvedokta principles of treatment particularly in terms of shatkriyakalas. The study of valvular heart disease with reference to Shat Kriyakala, showed that the pathogenesis of valvular heart disease can very well be arranged in Ayurvedokta  six stages of Shat Kriyakala and treatment could be framed as per different stages. With the help of modern investigations, these six stages could be diagnostically confirmed.


2021 ◽  
Vol 19 (3) ◽  
pp. 130-132
Author(s):  
Sarath Kumar Reddy B ◽  

Background: Ischemic heart disease (IHD) is one of the principle causes of morbidity and of mortality in women1. Ischemic heart disease may manifest clinically as either chronic stable angina or acute coronary syndrome2 (ACS). Traditional risk factors (hypertension, diabetes, etc.) contribute to the development of IHD in both women and men. Some risk factors are unique to women (e.g., pregnancy-related complications, menopause), which cause increased mortality in women Aim: To study the risk factors and clinical profile of ischemic heart disease in women. Materials And Methods: Hospital-based prospective, cross-sectional study done in 50 patients with ischemic heart disease. Patients with a history of Chest pain suggestive of ischemic heart diseases and Electrocardiogram and cardiac biomarkers suggestive of ischemic heart disease were included in the study. Results: Maximum incidence of ischemic heart diseases is seen in the 6th decade. Mean age is 58.92 + 2.8years. 64%of the patients presented with chest pain, and 36% patients presented without any chest pain. After chest pain, the most common symptom was palpitations, seen in 56% patients, followed by sweating (44%). 30% presented to the medical facility within 3hours. 88% were diagnosed with acute coronary syndrome, and 12% were diagnosed with chronic stable angina. Women specific risk factors include the pregnancy-related complications seen in 10% patients, menopause attained in 86% patients, PCOS seen in 08% patients, use of oral contraceptive pills noticed in 08% patients, Other risk factors identified were hypothyroidism in 16% patients, connective tissue disorders like rheumatoid arthritis seen in 12% of the patients. Conclusion: Awareness regarding atypical symptoms as well as other symptoms of IHD should be created among women to avoid delayed complications. Simple lifestyle modifications like physical activity, diet modifications, etc., will reduce the number of women at risk for IHD.


Author(s):  
Priyanka S. Gandhi ◽  
Bhavna N. Gamit

Background: In developing countries, Ischemic heart diseases (IHD) is one of the leading causes of morbidity and mortality. The underlying pathology of CAD is atherosclerosis. When this atherosclerotic plaque ruptures, platelets play a crucial role in the prothrombotic events and forms a thrombus on this plaque and as a result coronary artery gets occluded causing ischemia and infarction. Platelet contains many chemokines, cytokines and growth factors. Release of these factors along with interaction with endothelial cells and leukocytes promotes inflammation and progression of atherosclerosis. We aimed to investigate the association between platelet volume indices in patients with diagnosis of Ischemic heart disease in comparison with control group.Methods: By using automated cell counter platelet count and platelet volume indices - were compared with Normal healthy or non-cardiac chest pain patients with the use of unpaired t test.Results: In the present study, we demonstrated that platelet count is significantly low and MPV and PDW are significantly high in Ischemic heart disease as compared to patients with noncardiac chest pain or healthy subjects. The correlation of MPV with PC revealed an inverse correlation between the patients of IHD and healthy or non-cardiac chest pain patients which is statistically significant.Conclusions: The platelet volume indices are an important, simple, effortless and a cost-effective tool useful in predicting the development of an acute coronary event sometimes in the near future and therapeutic modification for improved patient’s cardiovascular care.


KYAMC Journal ◽  
2013 ◽  
Vol 3 (1) ◽  
pp. 223-234
Author(s):  
Md Saiful Islam ◽  
Md Annaz Mus Sakib ◽  
Ranjan Talukder ◽  
Sheikh Mohammed Taslim Yusuf

Background: Echocardiography is a non-invasive, on-injurious, relatively cheap and useful   imaging technique for the evaluation of cardiac diseases. The procedure has reliable levels of  accuracy. Echocardiography commenced at the Cardiology Department of Khawja Yunus Ali   Medical College Hospital,Enayetpur Sirajgonj,Bangladesh since 2004.The aim of this study is to  report our experience with the procedure, and to define the clinical cases seen in our setting.Methods: This is a retrospective analysis of a prospectively collected data. Echocardiography was  performed using Aloka Prosound-SSD 5500 SV echocardiograph equipped with 2.5-5.0 MHz   transducer.  Results: During the period of 6 months under review (July 2011-December 2011), 1883 procedures  were performed. Those reports were reviewed for demographic parameter, indications for the procedure and the main echocardiographic diagnoses. The mean age of the 1883 individuals   studied was 50 +/- 18.67 years (10-90). There were 1221 men and 662 women. Four hundred   ninety eight(498) (26.45%) had Ischemic Heart Disease, 229(12.16%) subjects were Hypertensive Heart disease,160 subjects (8.5%) had rheumatic heart disease while 62,(3.3%) had   cardiomyopathy. Pericardial diseases, corpulmonale, congenital heart diseases, were present in 36(1.92%), 35 (1.85%), 88(4.67%), respectively. Seven hundred and Seventy Five (41.1%) subjects had normal study.   Conclusion: Ischemic heart disease was found to be the most prevalent cardiac condition in this study. The relatively frequent diagnoses of Hypertensive heart Disease, valvular heart disease, cardiomyopathies and pericardial diseases reflect the impact of infections on the cardiovascular   health of adult Bangladeshis. We suggest that prevention and treatment of cardiac diseases in our setting should among other things focus on life style modification, Ceasation of smoking,regular exercise, blood pressure and blood glucose control and early treatment of infections causing heart   diseases.DOI: http://dx.doi.org/10.3329/kyamcj.v3i1.13657KYAMC Journal Vol. 3, No.-1, June 2012 p.223-224


Author(s):  
Hsin-I Shih ◽  
Tzu-Yuan Chao ◽  
Yi-Ting Huang ◽  
Yi-Fang Tu ◽  
Tzu-Ching Sung ◽  
...  

Natural disasters have negative health impacts on chronic diseases in affected populations. Severely affected areas are usually rural areas with limited basic infrastructure and a population have that has limited access to optimal healthcare after a disaster. Patients with cardiovascular diseases are required to maintain quality care, especially after disasters. A population-based case-control study enrolled adults from the National Health Insurance Registry who had ischemic heart disease and cerebrovascular disease histories and lived in the area affected by Typhoon Morakot in 2009. Monthly medical visits for acute cerebrovascular and ischemic heart diseases markedly increased at approximately 1–2 months after the typhoon. Survival analysis during the two years following the typhoon indicated a significant increase in mortality in adults with an acute ischemic heart disease history who lived in the severely affected area. Mortality hazard analysis showed that among affected adults with previous cerebrovascular diseases and acute ischemic heart diseases, patients with diabetes (adjusted hazard ratio [HR]: 1.3–1.7), Chronic Kidney Disease (CKD) (adjusted HR: 2.0–2.7), chronic obstructive pulmonary diseases (COPD) and asthma (adjusted HR: 1.7–2.1), liver cirrhosis (adjusted HR: 2.3–3.3) and neoplasms (adjusted HR: 1.1–2.1) had significantly increased mortality rates. Consequently, high-quality and accessible primary healthcare plans should be made available to maintain and support affected populations after disasters.


2018 ◽  
Vol 15 (2) ◽  
pp. 25-32
Author(s):  
Sangita Shrestha ◽  
Shova Laxmi Bajracharya

Background and Aims: Ischemic Heart Disease (IHD) is the number one cause of morbidity and mortality among the in-patient of different cardiac hospital of developing countries like Nepal. The prevalence of IHD is high with significant associated risk factors that include tobacco use, history of hypertension, family history and age. Though IHD can cause life-threatening conditions like myocardial infarction, yet it is preventable disease. The objective of the study was to study the risk factors associated with ischemic heart diseases among population attending selected cardiac hospitals of Kathmandu.Methods: Hospital- based pair matched case-control was conducted among the patients with IHD at Manmohan Cardiothoracic Vascular and Transplant Centre (MCTVC) and Shahid Gangalal National Heart Center (SGNHC). Non- random purposive sampling technique was applied and sample size was calculated as 105 (35 cases and 70 controls). Case and control were matched with age (Å} 2 years) and sex from the same hospitals. Ethical approval was taken from Institutional review board, Institute of medicine. Informed consent was obtained prior to information collection, after explaining about the purpose of the study to the entire participants. Only interested participants were included in the study. Confidentiality of the subject was ensured by collecting data in separate private room. Univariate associations between the risk factors and IHD under study was assessed by applying Chi-Square test and Fisher’s exact test and expressed as odds ratios with 95% confidence intervals. To assess the strength of association, the odds ratio was calculated.Results: 88.6% cases and 90% controls participants were of age 41 years and above and IHD was more common in male (60%) than female (40%). The participants who were not doing work-related moderate-intense activity are twice more likely to have IHD compared to controls (OR=2.276, p=0.049), similarly, hypertensive are two times (OR=2.276, p=0.049), obese are more than two times (OR=2.44, p=0.045), and participants with high waist to hip ratio are almost three times more likely to suffer from IHD (OR=2.88, p=0.013).Conclusions: The current smoking, physical inactivity, hypertension and waist to hip ratio tend to be the significant risk factors of IHD. Minimizing exposure to the identified risk factors can prevent burden of complex and expensive IHD treatment.


2016 ◽  
Vol 22 (2) ◽  
pp. 105-111 ◽  
Author(s):  
Na Li ◽  
Murugavel Ponnusamy ◽  
Meng-peng Li ◽  
Kun Wang ◽  
Pei-Feng Li

Approximately 2% of the human genome consists of protein-coding regions. Therefore, the majority of transcripts are noncoding RNAs, such as microRNA (miRNA) and long noncoding RNAs (lncRNAs). In ischemic heart disease, the majority of miRNAs are repressors or destabilizers of target messenger RNAs. The lncRNAs are a second class of noncoding RNAs that have recently gained attention for their roles in heart disease and in regulating the functions of miRNA. In this review, we summarize the role of miRNA in pathological cardiac hypertrophy and myocardial infarction. In addition, we discuss the functional interactions of miRNA and lncRNA and its impact on these ischemic heart diseases.


Sign in / Sign up

Export Citation Format

Share Document