scholarly journals OMPARATIVE ANTIFUNGAL ACTIVITY OF WILD AND CULTIVATED LEAVES OF FICUS CARICA LINN

2021 ◽  
Vol 29 (03) ◽  
Author(s):  
Nangial Bashir Ullah
Keyword(s):  
Antifungal Activity ◽  
Aspergillus Niger ◽  
Aspergillus Fumigatus ◽  
Fungal Species ◽  
Ficus Carica ◽  
Zone Of Inhibition ◽  
Polar Solvents ◽  
Common Fig ◽  
Cultivated Species ◽  
Tube Dilution

Objective: To compare the antifungal activity of wild and cultivated Ficus carica Linn (common fig) leaves extract Materials and Methods: An experimental study was conducted in the department of Botany Islamia College Peshawar from June 2016 to December 2016 which was shaped in 2021 into a research study in the Department of Community Medicine, Khyber Medical College Peshawar. The agar tube dilution method was used for antifungal activity of the extracts. Results: Comparison of Zone of Inhibition (%) in both Aspergillus niger and Aspergillus fumigatus colonies revealed that cultivated species of Ficus carica Linn (common fig locally known as Anjeer ) had more antifungal property against both the fungal species (63% and higher compared that to wild species having maximum zone of inhibition of 54.54%) with the exception of wild plant extract in polar solvent such as chloroform which had high level of antifungal activity (61.53%) only against Aspegillus fumigatus. The experiment also revealed that extracts from both wild and cultivated Ficus carica Linn leaves in polar solvents such as methanol( also written and referred to methanolic in the article) and chloroform showed higher level of antifungal activity against both the fungal species compared to extract taken in non-polar solvents.   Conclusion: Extract from cultivated species of Ficus carica Linn had higher level of activity against both the fungal species i.e. Aspergillus niger and Aspergillus fumigatus, especially extract taken in polar solvents. Key words: Ficus carica Linn, antifungal, tube dilution, zone of inhibition   

scholarly journals Evaluation of the anti-mycotic activity of Rosemary Oil Against Candida al-bicans

2019 ◽  
Vol 10 (2) ◽  
pp. 1228-1232
Author(s):  
Shebi S ◽  
Geetha RV ◽  
Lakshmi Thangavelu Lakshmi Thangavelu
Keyword(s):  
Antifungal Activity ◽  
Fungal Growth ◽  
Fungal Species ◽  
Diffusion Method ◽  
Zone Of Inhibition ◽  
Disc Diffusion Method ◽  
Rosemary Oil ◽  
Athlete’S Foot ◽  
Systemic Infections ◽  
Sterile Filter

An antifungal medication, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycoses such as athlete's foot, ringworm, candidiasis, serious systemic infections such as Cryptococcal meningitis, and others. In traditional medicine, extracts and essential oil from flowers and leaves are used in the belief they may be useful to treat a variety of fungal disorders. The aim of this study was to analyse the antimycotic properties of rosemary oil and its principal components. The Rosemary oil was screened for antifungal activity by the disc diffusion method. Activated cultures of Candida albicans in Sabouraud’s broth was adjusted to 0.5 McFarland standards [108cfu/ml]. 100 µl of the inoculum was introduced to molten Sabourauds dextrose agar and poured in the sterile Petri plates and allowed to set. Sterile filter paper discs (6.0 mm diameter) impregnated with 25µl, 50µl and 100µl /disc were placed on fungal seeded plates and incubated at 28oC for 48 hrs. Clear zones within which fungal growth was absent were measured and recorded as the diameter (mm) of complete growth inhibition. All the concentrations of the test solution inhibited the fungal species with varying degree of sensitivity. The extract showed good antifungal activity at different concentrations with a maximum zone of inhibition of 38 mm at concentration 100µl. This study provides a sample large enough to determine the antifungal properties of Rosemary oil and suggests further studies for possible therapeutic use.

scholarly journals PRESENTATION PATTERN AND FUNGAL AGENTS SPECTRUM CAUSING OTOMMYCOSIS

2018 ◽  
Vol 11 (1) ◽  
pp. 408
Author(s):  
Kassim Dekhil
Keyword(s):  
Candida Albicans ◽  
Aspergillus Niger ◽  
Aspergillus Fumigatus ◽  
Influencing Factors ◽  
Aspergillus Flavus ◽  
Species Distribution ◽  
Alternaria Alternata ◽  
Otitis Externa ◽  
Fungal Species ◽  
The Public

 Objective: This study was aimed to identify the public pattern of presentation, influencing factors, and sort the fungal species, distribution of sex of patients with otomycosis.Results: The predominant complaints were pruritus and found in 76 patients (88.73%), discomfort and pain found in 62 patients (72.09%), aural fullness in 48 patients (55.81%), tinnitus in 34 patients (39.53%), hearing impairment in 50 cases (58.31%), ear discharge in 22 patients (25.58%), and most of the symptoms seen in 36 patients (68.14%). The results showed a total of eight fungal species belong to six different genera, namely, Aspergillus, Candida, Penicillium, Rhizopus, Alternaria, and Cephalosporium were isolated during this study. Among identified fungi, Aspergillus niger was found to be the most prevalent fungal species with 35.71% followed by Candida albicans (27.55%), Aspergillus flavus (10.20%), Aspergillus fumigatus (8.16), Penicillium digitatum (6.12%) and Cephalosporium species (4.08%), and Rhizopus species (5.1%), while Alternaria alternata had the lowest percentage (6.54%).Conclusion: Otomycosis/mycotic otitis externa is still a common problem and there is a rise in the occurrence of otomycosis in latest years, especially in tropical and subtropical humid climates.

scholarly journals Antifungal Activity of Plant Extracts against Aspergillus niger and Rhizopus stolonifer

2014 ◽  
Vol 9 (11) ◽  
pp. 1934578X1400901 ◽  
Author(s):  
Venkatasaichaitanya Surapuram ◽  
William N. Setzer ◽  
Robert L. McFeeters ◽  
Hana McFeeters
Keyword(s):  
Antifungal Activity ◽  
Aspergillus Niger ◽  
Human Health ◽  
Plant Extracts ◽  
Food Supply ◽  
Fungal Species ◽  
Rhizopus Stolonifer ◽  
Antifungal Properties ◽  
Recent Advances

Despite recent advances in antifungal development, fungi remain a devastating threat to human health and compromise viability of the food supply. Plant based antimicrobials represent a vast untapped source with tremendous potential. Herein we present the antifungal properties of more than 50 plant extracts against two important human and agricultural pathogens, Aspergillus niger and Rhizopus stolonifer. Multiple extracts exhibit promising MIC values of less than 100 μg/mL and are reported for both fungal species.

scholarly journals Fungal Diversity in Droppings of Spot- Billed Pelican, Pelecanus philippensis

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Kavitha N ◽  
Zehra Amtuz
Keyword(s):  
Public Health ◽  
Aspergillus Niger ◽  
Health Risk ◽  
Aspergillus Fumigatus ◽  
Aspergillus Flavus ◽  
Fungal Diversity ◽  
Fungal Species ◽  
Public Health Risk

Birds are potential vectors of some diseases as their droppings pose public health risk and cause illness. Dust containing dry faeces after inhaling can infects humans. The prevalence of fungi from the faeces of birds in wetlands has not been previously determined. Hence, the present study was carried out to isolate and identify different fungal species present in the droppings of spot-billed pelican, Pelecanus philippensis. Among the fungal species identified Aspergillus flavus, Aspergillus niger and Aspergillus fumigatus were found to be dominating.

Anti-Fungal Activity of Cressa cretica, Leptadenia pyrotechnica and Pulicaria crispa, indigenous plants of Cholistan desert, Pakistan

2020 ◽  
Vol 18 ◽  
Author(s):  
Faheem Hadi ◽  
Tahir Maqbool ◽  
Sameera Khurshid ◽  
Aisha Nawaz ◽  
Saira Aftab ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Antifungal Activity ◽  
Aspergillus Niger ◽  
Aspergillus Flavus ◽  
Fungal Infections ◽  
Fungal Species ◽  
Fungal Activity ◽  
Aspergillus Ustus ◽  
Mother Tincture ◽  
Anti Fungal

Background: Fungal infections have always remain a problem and they are getting worse with passage of each year due to their resistance against available antibiotics. Natural ways of treatment with homoeopathic medicines made of mother tinctures of plants have no reported side effects and have been proved effective against many bacterial and fungal infections. Materials & Methods: Preparation of mother tinctures of plants Cressa cretica, Leptadenia pyrotechnica and Pulicaria crispa was done and used to evaluate the anti-fungal potential of these plants against potentially pathogenic fungal species like Aspergillus niger, Aspergillus flavus, Aspergillus ustus and Candida albicans by agar disc diffusion method. Each tincture was evaluated at 0.25 ml, 0.5 ml and 1 ml volume per disc and zone of inhibition was measured in millimetres and compared with commercial drug Fluconazole (2 mg/ml) which was used as standard. Results: The results showed that satisfactory anti-fungal activity of these plants in comparison to standard drug Fluconazole. The ratio of antifungal activity of Cressa cretica measured as the zone of growth inhibition of these cultures against Aspergillus niger, Aspergillus flavus, Aspergillus ustus and Candida albicans was 24 mm / 27 mm, 30mm / 28 mm, 23 mm/ 30 mm and 32 mm/ 30 mm respectively. In the case of Leptadenia pyrotechnica, the mother tincture’s antifungal activity was 32 mm / 27 mm, 30 mm / 28 mm, 17 mm/ 30 mm and 24 mm/ 30 mm. In case of our third plant Pulicaria crispa, antifungal activity came out to be 23 mm/ 27 mm, 26 mm/ 28 mm, 26 mm / 30 mm and 24 mm/ 30 mm. Conclusion: Our study proved that mother tincture of these plants can be a potential new therapy to treat fungal infections and has the potential to rule out fungal problems. Further research using mother tincture of these plants against other fungal species has the potential to prove them a safer and widespread anti-fungal homoeopathic medicine.

scholarly journals PRESENTATION PATTERN AND FUNGAL AGENTS SPECTRUM CAUSING OTOMMYCOSIS

2018 ◽  
Vol 11 (1) ◽  
pp. 408
Author(s):  
Kassim Dekhil
Keyword(s):  
Candida Albicans ◽  
Aspergillus Niger ◽  
Aspergillus Fumigatus ◽  
Influencing Factors ◽  
Aspergillus Flavus ◽  
Species Distribution ◽  
Alternaria Alternata ◽  
Otitis Externa ◽  
Fungal Species ◽  
The Public

 Objective: This study was aimed to identify the public pattern of presentation, influencing factors, and sort the fungal species, distribution of sex of patients with otomycosis.Results: The predominant complaints were pruritus and found in 76 patients (88.73%), discomfort and pain found in 62 patients (72.09%), aural fullness in 48 patients (55.81%), tinnitus in 34 patients (39.53%), hearing impairment in 50 cases (58.31%), ear discharge in 22 patients (25.58%), and most of the symptoms seen in 36 patients (68.14%). The results showed a total of eight fungal species belong to six different genera, namely, Aspergillus, Candida, Penicillium, Rhizopus, Alternaria, and Cephalosporium were isolated during this study. Among identified fungi, Aspergillus niger was found to be the most prevalent fungal species with 35.71% followed by Candida albicans (27.55%), Aspergillus flavus (10.20%), Aspergillus fumigatus (8.16), Penicillium digitatum (6.12%) and Cephalosporium species (4.08%), and Rhizopus species (5.1%), while Alternaria alternata had the lowest percentage (6.54%).Conclusion: Otomycosis/mycotic otitis externa is still a common problem and there is a rise in the occurrence of otomycosis in latest years, especially in tropical and subtropical humid climates.

scholarly journals Synthesis and antimicrobial activity of new 3,5-diarylidene-4-piperidone derivatives

2016 ◽  
Vol 81 (8) ◽  
pp. 859-870 ◽  
Author(s):  
Kulathooran Singaram ◽  
Dhamodaran Marimuthu ◽  
Selvakumar Baskaran ◽  
Venkataraman Ramaswamy
Keyword(s):  
Antimicrobial Activity ◽  
Antifungal Activity ◽  
Aspergillus Niger ◽  
Aspergillus Fumigatus ◽  
Structural Elucidation ◽  
Spectroscopic Methods ◽  
Microbial Strains

Three series of heteroaromatic analogs (twenty seven compounds) with monoketone linkers have been synthesized and evaluated for their antimicrobial activity against six microbial strains. Among them, 3,5-dibenzylidene-1-(3,5-dichloro-2-hydroxyphenylsulfonyl)piperidin-4-one 5e showed best antifungal activity against Aspergillus niger and Aspergillus fumigatus. Structural elucidation of the synthesized compounds was determined on the basis of various spectroscopic methods.

scholarly journals IN VITRO ANTIFUNGAL ACTIVITY OF FLOWER EXTRACT OF PANDANUS ODORATISSIMUS AGAINST DERMATOPHYTIC FUNGI

2018 ◽  
Vol 11 (9) ◽  
pp. 325
Author(s):  
Geethavani Babu ◽  
Balamuruganvelu Singaravelu ◽  
Sreenivasalu Reddy Vallapu ◽  
Srikumar Ramasundaram
Keyword(s):  
Antifungal Activity ◽  
Inhibitory Concentration ◽  
Diffusion Method ◽  
Zone Of Inhibition ◽  
Epidermophyton Floccosum ◽  
Dermatophytic Fungi ◽  
Pandanus Odoratissimus ◽  
In Vitro Antifungal Activity ◽  
Tube Dilution

Objective: The present study aimed to evaluate the antifungal activity of Pandanus odoratissimus oil against dermatophytic fungi, and it was compared against the two commonly used antifungal agent’s fluconazole and griseofulvin.Methods: A total of seven strains of dermatophytes were tested for antifungal activity using oil extracted from the flower of P. odoratissimus by using agar-well diffusion method and the zone of inhibition was compared with antifungal agent’s fluconazole and griseofulvin. Minimum inhibitory concentration (MIC) was determined using the tube-dilution method.Results and Conclusion: The zone of inhibition varied from 16.32 to 19.76 mm for fluconazole, 12.12–18.16 mm for griseofulvin, and 2.5–9.59 mm and 7.63–12.88 mm for 2.5 mg/ml and 5 mg/ml of P. odoratissimus extract, respectively. Epidermophyton floccosum and Trichophyton violaceum showed the lowest MIC value of 0.15 mg/ml. The results of our study have shown that the extract from P. odoratissimus can work significantly better against fungal diseases caused by dermatophytes. It was also found that it acts as a perfect alternative to the currently available antifungals such as fluconazole and griseofulvin. 

scholarly journals Antibacterial and Antifungal Activity of Ficus carica Plant Extract

2021 ◽  
pp. 1-9
Author(s):  
Firza Shafique ◽  
Uzma Naureen ◽  
Annam Zikrea ◽  
Qurban Ali ◽  
Rumana Sadiq ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Aspergillus Niger ◽  
Chloroform Extract ◽  
Fungal Species ◽  
Gram Negative Bacteria ◽  
Zone Of Inhibition ◽  
Gram Negative ◽  
Gram Positive Bacteria ◽  
Highly Sensitive

The development of antibiotic resistant bacteria causes many harmful effects on human and animal lives. In developing countries many expensive synthetic drugs are being used to cure diseases but they have many side effects. Therefore, there is need to develop new strategies to control microbial infections. Therefore, we decided to work on extracts of different parts of Ficus carica which have good activity against gram positive bacteria, gram negative bacteria and fungal species. Methanol and chloroform extracts of root, stem, leaves and fruits were prepared and zone of inhibition was measured by using well diffusion method against gram negative bacteria (Escherichia coli, Pseudomonas aeruginosa) two gram positive bacteria (Staphylococcus aureus, Bacillus cereus) and two fungal species Aspergillus niger and Aspergillus oryzae. methanol extract of leaves has high % yield (5.86%) and high zone of inhibition (23mm) against bacteria Escherichia coli and fungus Aspergillus niger (34mm). Bacteria Staphylococcus aureus was highly sensitive to chloroform extract with zone of inhibition 74mm while Escherichia coli was highly sensitive to metabolic extract with zone of inhibition 82mm. Chloroform extract has average zone of inhibition (56mm) and methanolic extract has average zone of inhibition (63mm).

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