scholarly journals Pain and dysfunction in amiotrophic side sclerosis

2021 ◽  
Author(s):  
Danielle Antoniazzi Kirscht Auermann D'Allembert Costa Sousa ◽  
Julia Magalhães Waybe Gonçalves ◽  
Marcela Ferreira de Andrade Rangel ◽  
Igor Roque de Paula ◽  
Mariana Asmar Alencar

Background: Amyotrophic Lateral Sclerosis (ALS) is a progressive disease characterized by degenerative symptoms of motor neurons. Pain has been described as a frequent symptom and is associated with a negative impact on the life of the person with ALS, however it is often neglected in clinical practice. There is a need for a better understanding of its characteristics and its relationship with the clinical and functional aspects of ALS. Objective: To investigate the occurrence and characteristics of pain in individuals with sporadic ALS and to verify the association between pain and clinical, functional and mobility aspects. Design and setting: This is an exploratory cross-sectional study carried out at the Neuromuscular Diseases Clinic of HC / UFMG, located in Belo Horizonte, Minas Gerais, Brazil. Methods: Aspects about pain (occurrence, intensity, duration and location), mobility (turning in bed, sitting and standing, standing and walking) and functionality (ALSFRS-R) were evaluated. A descriptive and comparative analysis was carried out between the groups and a binary logistic regression analysis. SPSS was used and the significance level was 5%. Result: 51 people (56.9 ± 11.3 years) were evaluated. A total of 62.7% reported pain. Predominant characteristics of pain: chronic (n = 29; 90.6%), moderate intensity (n = 20; 62.5%), in the leg (n = 12; 37.5%), 50% in more than one location . The population in pain was composed of: women (p = 0.038), longer illness time (p = 0.001), worse results in the ability to sit and stand (p = 0.033), stand up (p = 0.024) and walk ( p = 0.001) and worse score in the ALSFRS-R (p = 0.021). In the present study, regression showed that the inability to walk functionally increases the chance of pain in ALS patients by 5.3 times. Conclusion: Pain is a frequent symptom among people with ALS, and a greater functional limitation seems to be associated with its presence. It is important that future studies investigate this relationship better.

2018 ◽  
Vol 23 (2) ◽  
pp. 46-53 ◽  
Author(s):  
Sônia Rodrigues Dutra ◽  
Henrique Pretti ◽  
Milene Torres Martins ◽  
Cristiane Baccin Bendo ◽  
Miriam Pimenta Vale

ABSTRACT Objective: The aim of the present cross-sectional study was to assess the impact of malocclusion on the quality of life of children aged 8 to 10 years attending public elementary schools in Belo Horizonte, State of Minas Gerais, Brazil. Methods: The Brazilian version of the Child Perceptions Questionnaire 8-10 (CPQ8-10) was used to evaluate oral health-related quality of life. The children were examined for the diagnosis of malocclusion using the Dental Aesthetic Index (DAI). The data were analyzed by bivariate and multivariate descriptive statistics using Poisson regression at a 5% significance level. A total of 270 children participated in the study. Results: Children with normal occlusion or mild malocclusion (DAI ≤ 25) were 56% less likely (95%CI: 0.258-0.758; p= 0.003) to have their quality of life affected compared with children diagnosed with extremely severe malocclusion (DAI ≥ 36). Children with a maxillary anterior overjet ≥ 3 mm had higher CPQ8-10 mean scores (19.4; SD = 17.1) than those with an overjet < 3 mm (13.6; SD = 11.7; p= 0.038). Conclusions: Extremely severe malocclusion and pronounced maxillary anterior overjet were associated with a negative impact on quality of life.


2020 ◽  
Vol 29 (10) ◽  
pp. 2669-2677
Author(s):  
Agnieszka Bień ◽  
Ewa Rzońca ◽  
Marta Zarajczyk ◽  
Katarzyna Wilkosz ◽  
Artur Wdowiak ◽  
...  

Abstract Purpose The aim of the study was to assess QoL and identify and analyse its determinants in women with endometriosis. Methods The study was performed in 2019 in health centres in Lublin (Poland) on 309 women with diagnosed endometriosis. In order to verify which factors affect QoL of the study participants, regression for qualitative variables (CATREG) was used. The applied research instruments included the WHOQOL-BREF quality of life questionnaire, the Acceptance of Illness Scale (AIS), the Laitinen Pain Scale, and a general questionnaire. Results The overall QoL score of the respondents was 3.30, whereas their overall perceived health score was 2.37. The highest QoL scores were found for the psychological domain 13.33, whereas the lowest QoL were found for the physical domain 11.52. Women with endometriosis have a moderate level of illness acceptance (24.64) and experience daily pain of moderate intensity (5.83). Conclusion Women with endometriosis rate their overall QoL higher than their overall perceived health. Perceived QoL in women with endometriosis is most commonly associated with their acceptance of illness, BMI, negative impact of symptoms on the relationship with the partner, and dyspareunia. To improve these women’s lives, care should also respond to the social, emotional, and sexual issues resulting from the illness. Such interventions will contribute to improved comfort and QoL among these women.


2020 ◽  
Vol 73 (4) ◽  
Author(s):  
Nayara Figueiredo Vieira ◽  
José Ramón Martínez-Riera ◽  
Francisco Carlos Félix Lana

ABSTRACT Objectives: to evaluate the quality of primary care in leprosy control actions, to correlate effects on monitoring indicators. Methods: a cross-sectional study, conducted in Belo Horizonte, from July to September 2014. Interviews with 408 professionals were conducted through the application of a tool that assesses attributes of primary care in leprosy control actions, and monitoring indicators were calculated. Spearman correlation was used, significance level p < 0.05. Results: the overall score correlated with the percentage of cases treated in primary care and of family health staff coverage. The derived score correlated with the percentage of cases treated in primary care, and the essential score correlated with the proportion and rate of cases diagnosed, with grade 2 physical disability. Conclusions: the quality of leprosy control actions performed by primary care professionals produces impacts on health indicators, and developing strategies consistent with the reality of the territory is necessary.


2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Aline Mendes Silva de Pinho ◽  
Carolina Marques Borges ◽  
Mauro Henrique Nogueira Guimarães de Abreu ◽  
Efigênia Ferreira e Ferreira ◽  
Andréa Maria Duarte Vargas

The aim of this study was to determine the impact of periodontal disease on the quality of life of individuals with diabetes according to different clinical criteria (I-AAP, II-Beck, III-Machtei, IV-Lopez, V-Albandar, VI-Tonetti, and VII-CPI). This cross-sectional study sampled 300 individuals in Belo Horizonte, Brazil. The Oral Health Impact Profile was used to measure the impact of periodontal disease on quality of life. Prevalence of periodontal disease was 35.3%, 30.7%, 35.0%, 9.7%, 92.3%, 25.3%, and 75.3% using criteria I, II, III, IV, V, VI, and VII, respectively. The III-Machtei (P=0.043) and IV-Lopez (P<0.001) criteria were associated with OHIP-14; functional limitation was associated with IV-Lopez (P=0.006) and V-Albandar (P=0.018) criteria. Pain was only associated with V-Albandar criteria (P<0.001). Psychological discomfort was associated with the IV-Lopez (P=0.018) criteria. Physical disability was associated with the IV-Lopez (P=0.047) and V-Tonetti (P=0.046) criteria. Being handicapped was associated with the I-AAP (P=0.025) and II-Beck (P=0.041) criteria. Concepts of health and disease determined by clinical diagnostic criteria may influence the assessment of the impact of periodontal disease on diabetics' quality of life.


2014 ◽  
Vol 3 (3) ◽  
pp. 158
Author(s):  
Eny Retna Ambarwati ◽  
Ria Listiyani

Postpartum depression is a condition that may be experienced by women. If it is not addressed properly, it will have a negative impact. Determine the correlation between parity and the early stage of the marriage with the incidence of postpartum depression. This research used analytic observational method with cross sectional approach. The population in this research was postpartum mothers in Maternal Hospital Leonisa. The sampling was done using purposive sampling technique. The data analysis was done with univariate and bivariate analysis using Chi-square.The correlation between parity and the incidence of postpartum depression obtains the result of x<sup>2</sup> count of 22.864 and p value of 0.000 with df2 and the significance level of (α) at 5% (0.05) x table at 5.591. Therefore, Ho is rejected and Ha is accepted. The correlation between the early stage of the marriage variable with the incidence of postpartum depression obtains a result of x<sup>2</sup> count of 12.965 and p value of 0.000 with df 1, the significance level at 5% (0.05), x table at 3.481, therefore, Ho is rejected and Ha is accepted. There is a correlation between parity and the early stage of the marriage with the incidence of postpartum depression.


Author(s):  
Niels-Peter Brøchner Nygaard ◽  
Gert Frank Thomsen ◽  
Jesper Rasmussen ◽  
Lars Rauff Skadhauge ◽  
Bibi Gram

Background: The purpose of this study was to investigate the impact of age, musculoskeletal pain and ergonomic exposure on workability in the oldest group of workers. Methods: The study was a population based cross-sectional survey. The study population comprised citizens born between 1952–1966, living in Esbjerg municipality ultimo 2016 (n = 23,463). A questionnaire was sent electronically or by mail. The analysis included the working population only. A stereotype logistic regression was used with the primary dependent variable being workability and independent variables included age, musculoskeletal pain, and ergonomic exposure. Results: The response rate was 58% and the data demonstrated a significant negative association between age and workability. With excellent workability as a reference, the odds for poor workability increased by 97% being 60+ y compared to 50–55 y. Both moderate intensity and severe musculoskeletal pain in the back, shoulder and knee/hip all showed significantly higher odds for poor workability. Ergonomic exposures, such as standing/walking, working with back bent or twisted and carrying or lifting had a significant negative impact on workability. Conclusion: Age, musculoskeletal pain and ergonomic exposures showed a significant negative impact on workability in the oldest group of workers and should be targeted with preventive initiatives.


2015 ◽  
Vol 18 (2) ◽  
pp. 385-397 ◽  
Author(s):  
Luiz Fábio Machado Barbosa ◽  
Carla Jorge Machado

OBJECTIVE: To identify factors related to smoking among health workers of the National Health System in Belo Horizonte, Minas Gerais, Brazil. METHODS: A cross-sectional study based on a survey conducted between September 2008 and January 2009 with a stratified sample. Data on sociodemographic, health, employment, and work characteristics were analyzed. Poisson regression models with robust variance and estimation of unadjusted and adjusted prevalence ratios were used to establish associations at a 5% significance level for inclusion in the final model. RESULTS: In 1,759 questionnaires analyzed, in which the question related to smoking was answered, the overall prevalence of smoking was 15.7%. Reasonable relationship between requirements and available resources remained negatively correlated to smoking in the final model (PR = 0.75; 95%CI 0.58 - 0.96). The variables that remained positively associated with smoking were being male (PR = 1.75; 95%CI 1.36 - 2.25) and the following positions: community health workers (PR = 2.98; 95%CI 1.76 - 5.05), professionals involved in monitoring (PR = 3.86; 95%CI 1.63 - 5.01), administrative and other general services workers (PR = 2.47; 95%CI 1.51 - 4.05); technical mid-level workers (PR = 2.23; 95%CI 1.31 - 3.78), including nurses and practical nurses (PR = 2.07; 95%CI 1.18 - 3.64). CONCLUSION: Specific occupational subgroups were identified and should be prioritized in smoking cessation and prevention programs.


2014 ◽  
Vol 3 (3) ◽  
pp. 158
Author(s):  
Eny Retna Ambarwati ◽  
Ria Listiyani

Postpartum depression is a condition that may be experienced by women. If it is not addressed properly, it will have a negative impact. Determine the correlation between parity and the early stage of the marriage with the incidence of postpartum depression. This research used analytic observational method with cross sectional approach. The population in this research was postpartum mothers in Maternal Hospital Leonisa. The sampling was done using purposive sampling technique. The data analysis was done with univariate and bivariate analysis using Chi-square.The correlation between parity and the incidence of postpartum depression obtains the result of x<sup>2</sup> count of 22.864 and p value of 0.000 with df2 and the significance level of (α) at 5% (0.05) x table at 5.591. Therefore, Ho is rejected and Ha is accepted. The correlation between the early stage of the marriage variable with the incidence of postpartum depression obtains a result of x<sup>2</sup> count of 12.965 and p value of 0.000 with df 1, the significance level at 5% (0.05), x table at 3.481, therefore, Ho is rejected and Ha is accepted. There is a correlation between parity and the early stage of the marriage with the incidence of postpartum depression.


Author(s):  
Mohadese Saffari ◽  
Milad Salaj Mahmoudi ◽  
Ehsan Razyani ◽  
Mina Shayestefar

Background: Internet addiction, which is a result of increasing inevitable use of the Internet and smart phones, causes discomfort and serious social and occupational problems, consequently that can lead to some mental disorders such as depression. On the other hand, depression and Internet addiction are factors affecting students' academic performance. Objective: This study aimed to investigate Internet addiction, depression and their relation with academic failure in students of Semnan Allied Medical Sciences. Methods: In this cross-sectional study, all students who were in the 3rd and higher semesters were examined. Three questionnaires (demographic, Beck Depression Inventory, and the Internet Addiction Test by Young) were used. The academic failure was assessed using the student's grade point average in the previous 3 semesters. Collected data was analyzed through descriptive and inferential statistics methods at significance level of 0.05. Results: 170 students participated in this study. The correlation between depression and grade point average changes was negative (r=-0.19) and significant (p=0.01). Moreover, a positive (r=0.39) and significant (p=0.01) correlation was observed between depression and Internet addiction scores. Binary logistic regression analysis also indicated that students' depression score (P=0.04, OR1.04, CI 95%=1-1.08) and sex (P=0.008, OR=0.37, CI 95% = 0.17-0.77) can predict academic failure. Conclusion: Due to the observation of Internet addiction and depression in the students and effects of these disorders on their academic performance, it is necessary to educate students and families, identify risk factors and provide solutions to deal with it.


2020 ◽  
Vol 7 (2) ◽  
pp. 844-849
Author(s):  
Eti Sumiati ◽  
Herlinawati Herlinawati

Peningkatan kebutuhan akan air minum yang sehat dan praktis mendorong tumbuhnya Depot Air Minum Isi Ulang (DAMIU) dan hal ini merupakan dasar pilihan masyarakat untuk menggunakan air isi ulang, DAMIU berpotensi menimbulkan dampak negatif bagi kesehatan konsumen jika tidak ada regulasi yang efektif, Isu yang terjadi saat ini adalah rendahnya jaminan kualitas terhadap air minum yang dihasilkan. Jika tidak dikendalikan dengan maksimal, akan menimbulkan kerugian bagi kesehatan konsumen. Misalnya keracunan zat kimia persisten maupun penyebaran penyakit melalui air (water borne disease). Tujuan pada penelitian ini adalah untuk mengetahui  hubungan hygiene penjamah dengan jumlah coliform air minum pada DAMIU di Kecamatan Gunung Jati Kabupaten Cirebon Tahun 2016. Penelitian ini adalah explanatory research dengan rancangan cross sectional study, populasi penelitian adalah seluruh  Depot Air Minum Isi Ulang (DAMIU) yang berada di wilayah Kecamatan Gunung Jati Kabupaten Cirebon yang terdiri dari 28 DAMIU. Penentuan sampel dilakukan dengan menggunakan teknik Total sampling yaitu sebanyak 28 DAMIU. Metode pengumpulan data menggunakan wawancara, observasi dan pemeriksaan laboratorium. Instrumen yang digunakan adalah lembar kuesioner dan observasi serta botol sampel yang sudah disteril untuk pengambilan sampel pengujian mikrobiologis air minum. Data dalam penelitian ini dianalisis secara statistik dengan  menggunakan Uji Chi Square dengan tingkat kemaknaan 5% (0,05). Hasil uji statistik didapatkan bahwa variabel hygiene penjamah DAMIU (p=0,000) berhubungan dengan variabel coliform (p=0,05) atau dikatakan juga bahwa meningkatnya jumlah coliform pada DAMIU di Kecamatan Gunung Jati berhubungan dengan tingkat higyene penjamahnya.Kata Kunci : Hygiene Penjamah, Coliform, DAMIU ABSTRACTIncreased demand for safe drinking water and practically encourage the growth Depot Water Refill (DAMIU) and this is the basis of people's choice to use water refill, DAMIU potentially negative impact on the health of consumers if there is no effective regulation, Issue happened today is the low quality assurance of the drinking water produced. If not controlled to the maximum, it will cause harm to the health of consumers. Eg persistent chemical poisoning and the spread of disease through water (water borne disease). The purpose of this research was to determine the relationship of hygiene handlers by the number of coliform in drinking water in DAMIU Gunung Jati Subdistrict Cirebon Regency Year 2016. This research is explanatory research with cross sectional study, the study population was the whole Depot Water Refill (DAMIU) which located in the District Gunung Jati Cirebon comprising 28 DAMIU. The sampling was done by using total sampling as many as 28 DAMIU. Methods of data collection using interviews, observations and laboratory tests. The instruments used are questionnaires and observation sheets and sample bottles that have been sterilized for sampling microbiological testing of drinking water. The data were statistically analyzed using Chi Square test with significance level of 5% (0.05) The results of statistical test showed that the variables handlers DAMIU hygiene (p = 0.000) associated with coliform variables (p = 0.05) or say also that increasing the number of coliform DAMIU in District Gunung Jati associated with penjamahnya higyene level.Keywords: Hygiene handlers, Coliform, Depot Water Refill


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